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Variants in the ATP-Binding Cassette Transporter (ABCA7), Apolipoprotein E ε4, and the Risk of Late-Onset Alzheimer Disease in African Americans

Interview with Richard Mayeux, MD, MSc, author of Variants in the ATP-Binding Cassette Transporter (ABCA7), Apolipoprotein E ε4, and the Risk of Late-Onset Alzheimer Disease in African Americans




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Prevalence of a Healthy Lifestyle Among Individuals With Cardiovascular Disease in High-, Middle- and Low-Income Countries: The Prospective Urban Rural Epidemiology (PURE) Studyterview

Interview with Koon Teo, MB, PhD, author of Prevalence of a Healthy Lifestyle Among Individuals With Cardiovascular Disease in High-, Middle- and Low-Income Countries: The Prospective Urban Rural Epidemiology (PURE) Study




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Prenatal Valproate Exposure and Risk of Autism Spectrum Disorders and Childhood Autism

Interview with Jakob Christensen, PhD, author of Prenatal Valproate Exposure and Risk of Autism Spectrum Disorders and Childhood Autism




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Immunogenicity of 2 Doses of Human Papillomavirus Vaccine in Younger Adolescents Versus 3 Doses in Young Women: A Randomized Clinical Trial

Interview with Simon R. M. Dobson, MD, author of Immunogenicity of 2 Doses of Human Papillomavirus Vaccine in Younger Adolescents Versus 3 Doses in Young Women: A Randomized Clinical Trial




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Effect of Different Dosages of Oral Vitamin D Supplementation on Vitamin D Status in Healthy, Breastfed Infants: A Randomized Trial

Interview with Hope Weiler, RD, PhD, author of Effect of Different Dosages of Oral Vitamin D Supplementation on Vitamin D Status in Healthy, Breastfed Infants: A Randomized Trial




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Lutein + Zeaxanthin and Omega-3 Fatty Acids for Age-Related Macular Degeneration: The Age-Related Eye Disease Study 2 (AREDS2) Randomized Clinical Trial

Interview with Emily Y. Chew, MD, author of Lutein + Zeaxanthin and Omega-3 Fatty Acids for Age-Related Macular Degeneration: The Age-Related Eye Disease Study 2 (AREDS2) Randomized Clinical Trial




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Effect of Escitalopram on Mental Stress-Induced Myocardial Ischemia: Results of the REMIT Trial

Interview with Christopher O'Connor, MD, author of Effect of Escitalopram on Mental Stress-Induced Myocardial Ischemia: Results of the REMIT Trial




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Roux-en-Y Gastric Bypass vs Intensive Medical Management for the Control of Type 2 Diabetes, Hypertension, and Hyperlipidemia: The Diabetes Surgery Study Randomized Clinical Trial

Interview with Sayeed Ikramuddin, MD, author of Roux-en-Y Gastric Bypass vs Intensive Medical Management for the Control of Type 2 Diabetes, Hypertension, and Hyperlipidemia: The Diabetes Surgery Study Randomized Clinical Trial




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Short-term vs Conventional Glucocorticoid Therapy in Acute Exacerbations of Chronic Obstructive Pulmonary Disease: The REDUCE Randomized Clinical Trial

Interview with Jonas Rutishauser, MD, author of Short-term vs Conventional Glucocorticoid Therapy in Acute Exacerbations of Chronic Obstructive Pulmonary Disease: The REDUCE Randomized Clinical Trial




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Effect of an Outpatient Antimicrobial Stewardship Intervention on Broad-Spectrum Antibiotic Prescribing by Primary Care Pediatricians: A Randomized Trial

Interview with Jeffrey S. Gerber, MD, PhD, author of Effect of an Outpatient Antimicrobial Stewardship Intervention on Broad-Spectrum Antibiotic Prescribing by Primary Care Pediatricians: A Randomized Trial




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Use of Advanced Treatment Technologies Among Men at Low Risk of Dying From Prostate Cancer

Interview with Brent K. Hollenbeck, MD, MS, author of Use of Advanced Treatment Technologies Among Men at Low Risk of Dying From Prostate Cancer




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Effect of Home Blood Pressure Telemonitoring and Pharmacist Management on Blood Pressure Control: A Cluster Randomized Clinical Trial

Interview with Karen L. Margolis, MD, MPH, author of Effect of Home Blood Pressure Telemonitoring and Pharmacist Management on Blood Pressure Control: A Cluster Randomized Clinical Trial




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The Paradox of Disease Prevention: Celebrated in Principle, Resisted in Practice

Interview with Harvey V. Fineberg, MD, PhD, author of The Paradox of Disease Prevention: Celebrated in Principle, Resisted in Practice




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Geographic Variation in Cardiovascular Procedure Use Among Medicare Fee-for-Service vs Medicare Advantage Beneficiaries

Interview with Daniel D. Matlock, MD, MPH, author of Geographic Variation in Cardiovascular Procedure Use Among Medicare Fee-for-Service vs Medicare Advantage Beneficiaries




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The State of US Health, 1990-2010: Burden of Diseases, Injuries, and Risk Factors

Interview with Christopher J. L. Murray, MD, DPhil, author of The State of US Health, 1990-2010: Burden of Diseases, Injuries, and Risk Factors




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Risk Factors Associated With Suicide in Current and Former US Military Personnel

Interview with Cynthia A. LeardMann, MPH, author of Risk Factors Associated With Suicide in Current and Former US Military Personnel




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Concurrent Naltrexone and Prolonged Exposure Therapy for Patients With Comorbid Alcohol Dependence and PTSD: A Randomized Clinical Trial

Interview with Edna B. Foa, PhD, author of Concurrent Naltrexone and Prolonged Exposure Therapy for Patients With Comorbid Alcohol Dependence and PTSD: A Randomized Clinical Trial




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Sofosbuvir and Ribavirin for Hepatitis C Genotype 1 in Patients With Unfavorable Treatment Characteristics: A Randomized Clinical Trial

Interview with Anthony S. Fauci, MD, author of Sofosbuvir and Ribavirin for Hepatitis C Genotype 1 in Patients With Unfavorable Treatment Characteristics: A Randomized Clinical Trial




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Effects of a Fixed-Dose Combination Strategy on Adherence and Risk Factors in Patients With or at High Risk of CVD: The UMPIRE Randomized Clinical Trial

Interview with Simon Thom, MB,BS, MD, author of Effects of a Fixed-Dose Combination Strategy on Adherence and Risk Factors in Patients With or at High Risk of CVD: The UMPIRE Randomized Clinical Trial




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Industry-Sponsored Clinical Trials in Emerging Markets: Time to Review the Terms of Engagement

Interview with Stephen MacMahon, DSc, FMedSci, author of Industry-Sponsored Clinical Trials in Emerging Markets: Time to Review the Terms of Engagement




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Menopausal Hormone Therapy and Health Outcomes During the Intervention and Extended Poststopping Phases of the Women's Health Initiative Randomized Trials

Interview with JoAnn E. Manson, MD, author of Menopausal Hormone Therapy and Health Outcomes During the Intervention and Extended Poststopping Phases of the Women's Health Initiative Randomized Trials




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Universal Glove and Gown Use and Acquisition of Antibiotic-Resistant Bacteria in the ICU: A Randomized Trial

Interview with Anthony D. Harris, MD, author of Universal Glove and Gown Use and Acquisition of Antibiotic-Resistant Bacteria in the ICU: A Randomized Trial




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Metoclopramide in Pregnancy and Risk of Major Congenital Malformations and Fetal Death

Interview with Björn Pasternak, MD, PhD, author of Metoclopramide in Pregnancy and Risk of Major Congenital Malformations and Fetal Death




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World Medical Association's Declaration of Helsinki: Ethical Principles for Medical Research Involving Human Subjects

Howard Bauchner, MD interviews Ramin W. Parsa-Parsi, MD, MPH and Heikki Pälve, MD, PhD about the World Medical Association's Declaration of Helsinki: Ethical Principles for Medical Research Involving Human Subjects




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Association Between Influenza Vaccination and Cardiovascular Outcomes in High-Risk Patients: A Meta-analysis

Interview with Jacob A. Udell, MD, MPH, FRCPC, author of Association Between Influenza Vaccination and Cardiovascular Outcomes in High-Risk Patients: A Meta-analysis




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JEffect of Weight Reduction and Cardiometabolic Risk Factor Management on Symptom Burden and Severity in Patients With Atrial Fibrillation: A Randomized Clinical Trial

Interview with Prashanthan Sanders, MBBS, PhD, author of Effect of Weight Reduction and Cardiometabolic Risk Factor Management on Symptom Burden and Severity in Patients With Atrial Fibrillation: A Randomized Clinical Trial




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Effect of Micronutrient Supplementation on Disease Progression in Asymptomatic, Antiretroviral-Naive, HIV-Infected Adults in Botswana

Interview with Marianna K Baum, PhD, author of Effect of Micronutrient Supplementation on Disease Progression in Asymptomatic, Antiretroviral-Naive, HIV-Infected Adults in Botswana




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Effect of Communication Skills Training for Residents and Nurse Practitioners on Quality of Communication With Patients With Serious Illness: A Randomized Trial

Interview with J. Randall Curtis, MD, MPH, author of Effect of Communication Skills Training for Residents and Nurse Practitioners on Quality of Communication With Patients With Serious Illness: A Randomized Trial




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Weight Change and Health Outcomes at 3 Years After Bariatric Surgery Among Individuals With Severe Obesity

Interview with Anita P. Courcoulas, MD, MPH, author of Weight Change and Health Outcomes at 3 Years After Bariatric Surgery Among Individuals With Severe Obesity




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Calcium-Channel Blocker-Clarithromycin Drug Interactions and Acute Kidney Injury

Interview with Amit X. Garg, MD, PhD, author of Calcium-Channel Blocker-Clarithromycin Drug Interactions and Acute Kidney Injury




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Cognitive Behavioral Therapy Plus Amitriptyline for Chronic Migraine in Children and Adolescents

Interview with Scott W. Powers, PhD, author of Cognitive Behavioral Therapy Plus Amitriptyline for Chronic Migraine in Children and Adolescents




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Effect of Vitamin E and Memantine on Functional Decline in Alzheimer Disease: The TEAM-AD VA Cooperative Randomized Trial

Interview with Maurice W. Dysken, MD, author of Effect of Vitamin E and Memantine on Functional Decline in Alzheimer Disease: The TEAM-AD VA Cooperative Randomized Trial




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Calcium Density of Coronary Artery Plaque and Risk of Incident Cardiovascular Events

Interview with Michael H. Criqui, MD, MPH, author of Calcium Density of Coronary Artery Plaque and Risk of Incident Cardiovascular Events




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Effect of 3 to 5 Years of Scheduled CEA and CT Follow-up to Detect Recurrence of Colorectal Cancer: The FACS Randomized Clinical Trial

Interview with John N. Primrose, MD, FRCS, author of Effect of 3 to 5 Years of Scheduled CEA and CT Follow-up to Detect Recurrence of Colorectal Cancer: The FACS Randomized Clinical Trial




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Clinical Trial Evidence Supporting FDA Approval of Novel Therapeutic Agents, 2005-2012

Interview with Joseph S. Ross, MD, MHS, author of Clinical Trial Evidence Supporting FDA Approval of Novel Therapeutic Agents, 2005-2012




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Blood Pressure Trajectories in Early Adulthood and Subclinical Atherosclerosis in Middle Age

Interview with Norrina B. Allen, PhD, MPH, author of Blood Pressure Trajectories in Early Adulthood and Subclinical Atherosclerosis in Middle Age




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Association of Varying Number of Doses of Quadrivalent Human Papillomavirus Vaccine With Incidence of Condyloma

Interview with Lisen Arnheim-Dahlström, PhD, author of Association of Varying Number of Doses of Quadrivalent Human Papillomavirus Vaccine With Incidence of Condyloma




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Associations of Housing Mobility Interventions for Children in High-Poverty Neighborhoods With Subsequent Mental Disorders During Adolescence

Interview with Ronald C. Kessler, PhD, author of Associations of Housing Mobility Interventions for Children in High-Poverty Neighborhoods With Subsequent Mental Disorders During Adolescence




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Warfarin, Kidney Dysfunction, and Outcomes Following Acute Myocardial Infarction in Patients With Atrial Fibrillation

Interview with Juan Jesús Carrero, PhD(Pharm and Med), author of Warfarin, Kidney Dysfunction, and Outcomes Following Acute Myocardial Infarction in Patients With Atrial Fibrillation




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Comparison of 2 Transvaginal Surgical Approaches and Perioperative Behavioral Therapy for Apical Vaginal Prolapse

Interview with Matthew D. Barber, MD, MHS, author of Comparison of 2 Transvaginal Surgical Approaches and Perioperative Behavioral Therapy for Apical Vaginal Prolapse




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Psychiatric Diagnoses and Psychoactive Medication Use Among Nonsurgical Critically Ill Patients Receiving Mechanical Ventilation

Interview with Derek C. Angus, MD, MPH, author of Psychiatric Diagnoses and Psychoactive Medication Use Among Nonsurgical Critically Ill Patients Receiving Mechanical Ventilation




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Web-Based Alcohol Screening and Brief Intervention for University Students: A Randomized Trial

Interview with Nicholas J. Horton, ScD, author of Web-Based Alcohol Screening and Brief Intervention for University Students: A Randomized Trial




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Interview with Henry Waxman (D, Calif), retiring from Congress after 20 terms.

Interview with Henry Waxman (D, Calif) who is retiring from Congress after 20 terms.




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A Systematic Assessment of Benefits and Risks to Guide Breast Cancer Screening Decisions

Interview with Nancy L. Keating, MD, MPH, author of A Systematic Assessment of Benefits and Risks to Guide Breast Cancer Screening Decisions




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Comparison of Balloon-Expandable vs Self-expandable Valves in Patients Undergoing Transcatheter Aortic Valve Replacement: The CHOICE Randomized Clinical Trial

Interview with Mohamed Abdel-Wahab, MD, author of Comparison of Balloon-Expandable vs Self-expandable Valves in Patients Undergoing Transcatheter Aortic Valve Replacement: The CHOICE Randomized Clinical Trial




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The Familial Risk of Autism

Interview with Sven Sandin, MSc, author of The Familial Risk of Autism




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Medical and legalized marijuana in Colorado

Interview with Larry Wolk, MD, MSPH, chief medical officer for the Colorado Department of Public Health, about medical and legalized marijuana in Colorado.




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Using Multiplexed Assays of Oncogenic Drivers in Lung Cancers to Select Targeted Drugs

Interview with Mark G. Kris, MD, author of Using Multiplexed Assays of Oncogenic Drivers in Lung Cancers to Select Targeted Drugs




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Effect of Physical Therapy on Pain and Function in Patients With Hip Osteoarthritis: A Randomized Clinical Trial

Interview with Kim L. Bennell, PhD, author of Effect of Physical Therapy on Pain and Function in Patients With Hip Osteoarthritis: A Randomized Clinical Trial




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Effect of Structured Physical Activity on Prevention of Major Mobility Disability in Older Adults: The LIFE Study Randomized Clinical Trial

Interview with Marco Pahor, MD, author of Effect of Structured Physical Activity on Prevention of Major Mobility Disability in Older Adults: The LIFE Study Randomized Clinical Trial