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Escape sites from the endo-lysosomal trafficking route manipulate exocytosis of nanoparticles in polar epithelium

Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM00174E, Paper
Lingling Wang, Yuting Li, Xi Liu, Liyun Xing, Ruinan Wu, Yuan Huang
MNPs escaping from early endosomes and late endosomes are prone to entering the ER/GA for efficient basolateral exocytosis. However, MNPs escaping from lysosomes are detained within cells by autophagosomes.
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Photothermal therapy: a novel potential treatment for prostate cancer

Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM00057A, Review Article
Zirui Dong, Kaming Xue, Anushikha Verma, Jian Shi, Zhihao Wei, Xiaotian Xia, Keshan Wang, Xiaoping Zhang
This review discussed photothermal therapy from basic information to its circumstances and potential in protate cancer treatment.
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Bioinspired ginsenoside Rg3 PLGA nanoparticles coated with tumor-derived microvesicles to improve chemotherapy efficacy and alleviate toxicity

Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM00159A, Paper
Shulei Zhang, Bo Zheng, Yiqi Wei, Yuhao Liu, Lan Yang, Yujiao Qiu, Jing Su, Mingfeng Qiu
Breast cancer, a pervasive malignancy affecting women, demands a diverse treatment approach including chemotherapy, radiotherapy, and surgical interventions.
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Telomerase: a nexus between cancer nanotherapy and circadian rhythm

Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM00024B, Minireview
Pramit Kumar Ghosh, Maddila Jagapathi Rao, Chandra Lekha Putta, Sandipan Ray, Aravind Kumar Rengan
The use of nanoparticles for identifying and suppressing telomerase presents promising opportunities for anticancer strategies, particularly in relation to circadian regulation.
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Exosomes encapsulated in hydrogels for effective central nervous system drug delivery

Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D3BM01055D, Review Article
Ziba Zakeri, Morteza Heiderzadeh, Azra Kocaarslan, Ecem Metin, Seyed Nasir Hosseini Karimi, Sepideh Saghati, Atay Vural, Göktuğ Akyoldaş, Kemal Baysal, Yusuf Yağcı, Yasemin Gürsoy-Özdemir, Savaş Taşoğlu, Reza Rahbarghazi, Emel Sokullu
The targeted delivery of pharmacologically active molecules, metabolites, and growth factors to the brain parenchyma has become one of the major challenges following the onset of neurodegeneration and pathological conditions.
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Correction: Clodronate-nintedanib-loaded exosome–liposome hybridization enhances the liver fibrosis therapy by inhibiting Kupffer cell activity

Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM90028F, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Keqin Ji, Mingrui Fan, Dong Huang, Lingna Sun, Bingqin Li, Ruoting Xu, Jiajing Zhang, Xuan Shao, Yanzuo Chen
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Recent progress in nanomaterials for bacteria-related tumor therapy

Biomater. Sci., 2024, 12,1965-1980
DOI: 10.1039/D3BM01952G, Review Article
Fuping Zhang, Shuyu Wang, Shuo Yang, Feihe Ma, Hui Gao
Recent progress in nanomaterials for bacteria-related tumor therapy in terms of chemotherapy, immunotherapy and synergistic therapy is summarized in this review in order to provide some insights into this emerging and rapidly growing research area.
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Nanotechnology-based delivery of therapeutics through the intranasal pathway and the blood–brain barrier for Alzheimer's disease treatment

Biomater. Sci., 2024, 12,2007-2018
DOI: 10.1039/D3BM02003G, Review Article
Mark-Jefferson Buer Boyetey, Yonghyun Choi, Hee-Young Lee, Jonghoon Choi
Drugs for Alzheimer's disease (AD) fail to exhibit efficacy in clinical trials for a number of reasons, a major one being blood–brain barrier (BBB) permeability.
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Recent advances in shape memory polymeric nanocomposites for biomedical applications and beyond

Biomater. Sci., 2024, 12,2033-2040
DOI: 10.1039/D4BM00004H, Review Article
Yifan Zheng, Yudi Du, Ling Chen, Wei Mao, Yuan Pu, Steven Wang, Dan Wang
Shape memory polymers (SMPs), which initiate shape transformation in response to environmental stimuli, have attracted significant attention in both academic research and technological innovation.
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Optimization of lipid assisted polymeric nanoparticles for siRNA delivery and cancer immunotherapy

Biomater. Sci., 2024, 12,2057-2066
DOI: 10.1039/D3BM02071A, Paper
Song Lin, Houjin Jing, Xiaojiao Du, Xianzhu Yang, Jun Wang
A siRNA delivery system was developed using clinically approved mPEG-b-PLGA, cationic lipid and ionizable lipid for siRNA delivery and cancer immunotherapy.
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Correction: A Y1 receptor ligand synergized with a P-glycoprotein inhibitor improves the therapeutic efficacy of multidrug resistant breast cancer

Biomater. Sci., 2024, 12,2165-2166
DOI: 10.1039/D4BM90022G, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Yinjie Wang, Zhenqi Jiang, Bo Yuan, Yuchen Tian, Lingchao Xiang, Yanying Li, Yong Yang, Juan Li, Aiguo Wu
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Type I and Type II Chemical Biology Toolbox to Overcome the Hypoxic Tumour Microenvironment for Photodynamic Therapy

Biomater. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D4BM00319E, Review Article
Minzi Ju, Lu Yang, Guowei Wang, Feng Zong, Yu Shen, Shuangshuang Wu, Xuna Tang, Decai Yu
Photodynamic therapy (PDT) is a minimally invasive therapeutic modality employed for the treatment of various types of cancers, localized infections, and other diseases. Upon illumination, the photo-excited photosensitizer generates singlet...
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A universal strategy to enhance photothermal conversion efficiency by regulating the molecular aggregation states for safe photothermal therapy of bacterial infections

Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM00412D, Paper
Hao Fu, Yongxin Zhang, Cheng Wang, Zhencheng Sun, Shuyi Lv, Minghui Xiao, Kaiyu Wu, Linqi Shi, Chunlei Zhu
A universal strategy is developed to remarkably enhance the photothermal conversion efficiency of photothermal materials. This advancement enables effective treatment of drug-resistant bacterial infections through safe photothermal therapy.
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Ultrasmall catechol-PEG-anchored ferrite nanoparticles for highly sensitive magnetic resonance angiography

Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D3BM02074F, Paper
Yanzhi Dong, Jiaojiao Wang, Ting Zhou, Jinbing Pan, Xu Wang, Shao-Kai Sun
We developed ultrasmall catechol-PEG-anchored ferrite nanoparticles for highly sensitive MRA. The probe enables the diagnosis of carotid artery stenosis and subsequent evaluation of reperfusion through a single injection.
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Applications of hydrogels in tissue-engineered repairing of temporomandibular joint diseases

Biomater. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D3BM01687K, Review Article
Xuan Wang, Fushuang Liu, Tianyi Wang, Yikai He, Yongwen Guo
Epidemiological studies reveal that symptoms of TMD occur in 60-70% of adults. The inflammatory damage caused by TMD can easily lead to defects in the articular disc, condylar cartilage, subchondral...
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Porphyrin-Based Covalent Organic Frameworks from Design, Synthesis to Biological Applications

Biomater. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D4BM00214H, Review Article
Open Access
Xin-Gui Li, Junjian Li, Jinfeng Chen, Liangmei Rao, Libin Zheng, Fei Yu, Yijing Tang, Jie Zheng, Jie Ma
Covalent organic frameworks (COFs) constitute a class of highly functional porous materials characterized by ordered structures, high crystallinity, and a substantial specific surface area, primarily composed of light atoms such...
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Exploring therapy transport from implantable medical devices using experimentally informed computational methods

Biomater. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D4BM00107A, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Lesley Trask, Niamh A. Ward, Ruth Tarpey, Rachel Beatty, Eimear Wallace, Joanne O'Dwyer, William Ronan, Garry P. Duffy, Eimear B. Dolan
Implantable medical devices that can facilitate therapy transport to localized sites are being developed for a number of diverse applications, including the treatment of diseases such as diabetes and cancer,...
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Vivo X100 Pro review: Capturing bison and bonfires, with the first flagship launched in 2024

The smartphone with its 225 grams isn’t exactly lightweight, but it looks classy with its trademark graphite glass finish rear panel




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Apple MacBook Pro M3: Polishing up, like a pro!

A versatile powerhouse with a stunning display, smooth gaming experience and long-lasting battery




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MWC 2024: Lenovo showcases transparent laptop, new ThinkBook lineup and more

The focus is on seamless connectivity and AI-experiences 




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Apple unveils new iPad Pro with advanced M4 chip and Apple Pencil Pro

Slimmer than ever, the device features a new Ultra Retina XDR display




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OPPO Find X7 Ultra review: A photographic powerhouse 

With Hasselblad-approved imaging prowess, this starrer on this phone is its quad-camera setup




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A shapeshifting sidekick! ASUS Zenbook Duo (2024)

The dual screen delight is back and updated to offer even more!




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AI laptops — the next big thing or more FOMO?

Reflecting on the week that was at Computex 2024, with all things AI coming our way!




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Snappy, but stumbles too! POCO F6 review

Does this sleek budget flagship punch above its weight?




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Google Pixel 9 Pro Fold review: A snapper that doesn’t shy away! 

Does the tech giant’s first foldable stack up well against its featherweight rivals?




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Apple Watch Series 10 review: Deeper dive into health, and water too!

With the arrival of Apple Watch Series 10, is it finally time for you to upgrade?




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Apple MacBook Pros... with more prowess

The laptop is now powered by the new M4 chip, which supports Apple Intelligence




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TSPSC extends date for submission of Group-IV applications




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Tips to prepare for the Sociology paper in the UPSC CSE Mains

Sociology is a popular choice for the optional subject in the UPSC Civil Services Exams (Mains). Here are a few tips on how to prepare for this subject




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Central universities faculty appointments to shift to CU-Chayan portal

The portal will provide a common platform for listing of vacancies, advertisements and jobs across all CUs




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The day of the apprentice 

A multi-city report reveals that during financial year 2022 various industries in India had been generous with their stipend payouts




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Employee resource groups shape the inclusion narrative  

Across companies, these units are proving their effectiveness in promoting the LGBTQ+ cause




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PM distributes 51,000 appointment letters via online Rozgar Mela

Government reached the doorsteps of those who had never received any benefits: Modi




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‘PSEs face a huge gap in technology training’




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New apprenticeship platform marked by extensive features

The upgraded platform manages the entire apprenticeship lifecycle




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Language, culture remain hurdles as Japan opens its doors to Indian professionals

Even if companies do not insist on knowledge of Japanese, experts say Indians must learn the language and adjust to the country’s culture




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Unemployed youth can apply for PM internship scheme from October 12

The number of opportunities posted to the portal of the PM Internship Scheme surged to 90,849 on October 11, 2024.




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What’s behind the widening gender wage gap in the US?

The first widening of the gender wage in 20 years is the latest indication that many women have paid a price for leaving the workforce at the height of the COVID-19 pandemic, either because they lost their jobs or because they quit because of caretaking responsibilities




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Officials plan express road network between Visakhapatnam and Bhogapuram for the upcoming international airport

Chief Minister mentioned about this road project in a recent meeting and we are currently preparing preliminary plans, says a senior VMRDA official




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Religious fervour marks Nagula Chavithi in Visakhapatnam

Many people visit snake pits at various places in the city and perform pujas




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NAMAHA Marathon to be organised in Visakhapatnam on November 10




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13-year-old boy found dead at home in Visakhapatnam




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Police Commissioner urges GVMC chief to fix street lights, CCTV issues to combat crime effectively in Visakhapatnam

He raises the issue of increasing road encroachments causing traffic snarls in the city at a review meet; GVMC Commissioner promises to solve all the problems




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Chhath Puja to be organised at RK Beach in Visakhapatnam on November 7




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Resident associations in Visakhapatnam urge State govt. to revoke levying of true-up charges

The announcement to levy the additional charges is surprising, given the NDA govt.’s pre-poll assurance that electricity rates would not be hiked, say association leaders




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Call to bridge the gap between the youth and elderly




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Andhra CM Chandrabu Naidu to virtually lay stone for 220KV sub-station in Anakapalli district




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Four-day national conference of ESICON in Visakhapatnam from November 7




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Stone laid for PV Sindhu Badminton Centre in Visakhapatnam

The government had allocated 2 acres of land in June 2021 to set up a center to promote sports