Boston Bruins goaltender Jaroslav Halak signed a one-year contract worth $2.25 million US, the team announced Friday. He was playing in the final season of a two-year contract.

The NHL is hoping to convince teams the league should move the 2020 draft to early June and hold it virtually, according to a report.

Veteran forward Kelly Babstock signed with the new Toronto franchise of the National Women's Hockey League on Saturday. The two-time all-star has 27 goals and 60 points in 65 games over four seasons.

A normal draft year would see NHL scouts and executives spend the spring crisscrossing Europe and North America collecting information. The circumstances surrounding a 2020 draft and the COVID-19 pandemic, however, aren't anything resembling normal.

Former Montreal Canadiens enforcer Georges Laraque's biggest challenge is trying to breathe clearly as he fights COVID-19 at a Montreal hospital. "The nights are the worst. I have fevers a couple times a night. I have to get up and take pills."

Pittsburgh Penguins superstar Sidney Crosby is easing the burden for many Pennsylvania families struggling during the COVID-19 virus.

The coronavirus pandemic has forced major professional sports leagues across North America to push the pause button. But even if the NHL, CFL, NBA or MLS are given the green light, many fans have reservations about returning to arenas until a vaccine for the virus is available.

While players are stuck in self isolation, they don’t need to worry about trying to stop Alexander Ovechkin’s “knuckleball” type shot.

Ontario Premier Doug Ford says the Toronto Maple Leafs' parent company has been in contact with the province about the possibility of Canada's biggest city serving as a so-called "hockey pod" for teams should the NHL resume its season.

Montreal Canadiens goaltender Carey Price has reached out to give support to two boys who lost their parents during the Nova Scotia mass shooting last month.

Avid curler Dale Kohlenberg, 64, got a lucky break when he was seconded to Iqaluit — and was quickly scouted for Team Nunavut.

It wasn’t all that long ago Brad Gushue wondered if he’d ever be a Brier champion after 13 appearances without ever hoisting the historic Tankard trophy. Times have changed in a hurry. Gushue is now a three-time Brier champion.

Team Homan, Canada’s 2018 Olympic women’s curling team and the 2017 World Women’s Curling Champions have announced that the team has parted ways with lead Lisa Weagle. 

Team Homan's decision to part ways with Lisa Weagle dramatically changed the look of one of the country's top rinks and put the all-star lead at the top of curling's free agent list.

The men's curling world championship in Glasgow was cancelled Saturday morning to prevent the spread of COVID-19. Brad Gushue and his rink from Newfoundland and Labrador was going to represent Canada after winning the Brier.

In the span of a few days, Canada's curling landscape has shifted dramatically. The country's past women's and men's Olympic teams and last year's women's world champion team have all split.

John Morris will play second for the Kevin Koe's team for at least the next 18 months heading into the Olympic trials in 2021.

The bonspiel took place in Edmonton March 11-14, starting the same day COVID-19 was declared a global pandemic.

The World Curling Federation announced Thursday it is proposing to the International Olympic Committee that the 2021 world curling championships will determine which countries will book their tickets to Beijing 2022.

Colleen Jones, Sidney Crosby among many preeminent local sports figures reacting in the aftermath of Sunday's killing rampage.

The time was right for Lisa Weagle to join forces with Olympic champion Jennifer Jones. Jones told CBC Sports' Anastasia Bucsis that the latest addition to her five-person rink "was like the clouds parted and the sun came out."

Will he, given his obsession with the economy?

I just hate it when my fellow Italian-Americans squabble.

He’s not rising to the challenge of the coronavirus pandemic. He’s shriveling into nothingness.

They’re pandemic partners, and that’s double trouble.

The notion that he is bound for four more years is pure superstition.

Is the Republican indulgence of the president bottomless?

Join our Facebook live on Thursday at noon with Dr. Roselyn Wilson a psychiatrist at St. Joseph’s Healthcare Hamilton’s Youth Wellness Centre. She'll talk with us about how COVID-19 is heightening anxiety in some young people. We'll talk about how to help the young people in your life through the pandemic.

Flattening the curve has been so successful and two areas around Hamilton — Brant and Haldimand-Norfolk — haven't had a new case of COVID-19 in three days, and Burlington has only had two.

The province says no one has to tell others if they get COVID-19. The same goes for businesses or landlords, should employees or tenants get sick. But should you tell?

Two additional men have been charged with first-degree murder in the death of a 17-year-old Brampton boy shot and killed on New Year's Eve.

Curbside pickups offer a bit of hope after months of being shuttered by COVID-19, but while retailers are happy to start getting back to business some are raising questions of fairness and access to opportunity.

A Toronto law firm has filed to launch a class action lawsuit against a Niagara Falls long-term care home where 18 residents have died from COVID-19, saying the home had a pub night in the midst of the pandemic.

The COVID-19 pandemic may be keeping families physically distant, but that doesn't mean you can't show someone you care.

Flurries or rain showers are in the forecast for Hamilton on Friday, Environment Canada says.

Sofina Foods plants in Burlington and Mississauga have each had an employee test positive.

Dr. Roselyn Wilson, a psychiatrist at St. Joseph’s Healthcare Hamilton’s Youth Wellness Centre, offers some tips to help young people cope with the stress and anxiety they face while on lockdown under COVID-19.

Hamilton Conservation Authority is re-opening the Hamilton-to-Branford Rail Trail, while the city announced the reopening of the Hamilton Waterfront Trail, between Confederation Park and the Burlington Lift Bridge.

Normal life is slowly resuming as the city of Hamilton begins to relax tight measures set in place because of COVID-19. Mayor Fred Eisenberger said now it's up to the public to help the city move in the right direction by continuing to stay two metres apart from each other and be cautious.

McMaster University is planning for fewer international students, more deferred acceptance offers and online teaching for the thousands who are attending as the start of a new school year looms in the near future and in the middle of the COVID-19 pandemic.

The general field of quantitative biology has advanced significantly on the back of recent improvements in both sequencing technology and proteomics methods. The development of high-throughput, short-read sequencing has revolutionized RNA-based expression studies, while improvements in proteomics methods have enabled quantitative studies to attain better resolution. Here we introduce methods to undertake global analyses of gene expression through RNA and protein quantification in Xenopus embryos and tissues.

Quantifying RNA is an important and necessary step before most RNA analysis techniques. Methods for quantifying RNA can be classified into two categories: ultraviolet (UV) spectrophotometric methods, which are based on the absorption spectra of the purine and pyrimidine bases; and fluorescent dye-based methods, which measure the fluorescence intensity of dyes that selectively fluoresce when bound to nucleic acids. If the RNA sample is pure (i.e., without significant amounts of contaminants such as proteins, phenol, agarose, or other nucleic acids), UV spectrophotometric measurement of the amount of UV irradiation absorbed by the bases is simple and accurate. However, if the sample contains significant quantities of impurities or if the concentration of RNA is very low, it is better to use fluorescent dye-based methods. An overview of spectrophotometric and fluorescent dye-based RNA quantification methods is given here, as are several options for storing purified RNA preparations. Proper storage of RNA samples is important; it can help minimize RNase contamination and consequent sample degradation.

The Xenopus oocyte is a unique model system, allowing both the study of complex biological processes within a cellular context through expression of exogenous mRNAs and proteins, and the study of the cell, molecular, and developmental biology of the oocyte itself. During oogenesis, Xenopus oocytes grow dramatically in size, with a mature oocyte having a diameter of ~1.3 mm, and become highly polarized, localizing many mRNAs and proteins. Thus, the mature oocyte is a repository of maternal mRNAs and proteins that will direct early embryogenesis prior to zygotic genome transcription. Importantly, the Xenopus oocyte also has the capacity to translate exogenous microinjected RNAs, which has enabled breakthroughs in a wide range of areas including cell biology, developmental biology, molecular biology, and physiology. This introduction outlines how Xenopus oocytes can be used to study a variety of important biological questions.

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