re LncRNA <i>SNORD3A</i> specifically sensitizes breast cancer cells to 5-FU by sponging miR-185-5p to enhance UMPS expression By feeds.nature.com Published On :: 2020-05-07 Full Article
re NF-kappa B interacting long noncoding RNA enhances the Warburg effect and angiogenesis and is associated with decreased survival of patients with gliomas By feeds.nature.com Published On :: 2020-05-07 Full Article
re MicroRNA let-7c (MIRLET7C; let-7c), miR-99a and miR-125b as prognostic markers of luminal breast cancer By feeds.nature.com Published On :: 2014-12-18 Studies in patient samples and cell culture suggest let-7c, miR-99a and miR-125b could serve as prognostic markers in patients with estrogen receptor–positive luminal breast cancers. Full Article
re Chromosome 11 open reading frame 30 (C11orf30), calpain small subunit 1 (CAPNS1; CAPN4), signal transducer and activator of transcription 6 (STAT6) and ankyrin repeat domain 27 (ANKRD27) as diagnostic markers for eosinophilic esophagitis (EoE) By feeds.nature.com Published On :: 2014-12-18 Genomewide association studies identified four genes that could serve as diagnostic markers and/or therapeutic targets for EoE. Full Article
re Extending therapeutic protein half-lives via fusion to affibodies with pH-dependent binding to neonatal Fc receptor By feeds.nature.com Published On :: 2014-12-18 Fusing therapeutic proteins to affibodies with pH-dependent binding to neonatal Fc receptor could improve the proteins' half-lives. Full Article
re VEGF receptor (VEGFR) By feeds.nature.com Published On :: 2014-12-18 Zebrafish studies suggest VEGFR inhibitors could help treat tuberculosis. Full Article
re HIV reverse transcriptase By feeds.nature.com Published On :: 2014-12-18 In vitro studies have identified indolylarylsulfone derivatives that could help treat HIV infection. Full Article
re Epidermal growth factor receptor 1 (EGFR1; ErbB1; HER1); HER2 (EGFR2; ErbB2; neu); HER3 (EGFR3; ErbB3); VEGF By feeds.nature.com Published On :: 2014-12-18 Tumor cell and mouse studies suggest tetravalent antibodies that target four different antigens could help treat cancers resistant to HER-targeted therapies. Full Article
re Cyclin dependent kinase 7 (CDK7); v-myc myelocytomatosis viral related oncogene neuroblastoma derived (MYCN; NMYC) By feeds.nature.com Published On :: 2014-12-18 In vitro and mouse studies suggest THZ1, a covalent CDK7 inhibitor, could help treat neuroblastoma and other cancers driven by MYCN and other c-MYC (MYC)-family oncoproteins. Full Article
re Estrogen receptor; LYN kinase (LYN); phosphoinositide 3-kinase (PI3K) By feeds.nature.com Published On :: 2014-12-18 Studies in mice and human samples suggest inhibiting LYN could help treat estrogen receptor–positive breast cancers resistant to anti-estrogen therapy. Full Article
re Resurrecting a magic bullet By feeds.nature.com Published On :: 2014-12-18 Heidelberg Pharma has resuscitated a long-dead ADC toxin with updated conjugation techniques, and its partner Roche has thrown the company a lifeline that could help validate the platform. Full Article
re Tissue-resident ductal macrophages survey the mammary epithelium and facilitate tissue remodelling By feeds.nature.com Published On :: 2020-04-27 Full Article
re In vitro capture and characterization of embryonic rosette-stage pluripotency between naive and primed states By feeds.nature.com Published On :: 2020-05-04 Full Article
re Differentiation of transplanted haematopoietic stem cells tracked by single-cell transcriptomic analysis By feeds.nature.com Published On :: 2020-05-04 Full Article
re FBP1 loss disrupts liver metabolism and promotes tumorigenesis through a hepatic stellate cell senescence secretome By feeds.nature.com Published On :: 2020-05-04 Full Article
re MicroRNA binding site polymorphism in inflammatory genes associated with colorectal cancer: literature review and bioinformatics analysis By feeds.nature.com Published On :: 2020-03-23 Full Article
re Oncolytic adenovirus encoding LIGHT (TNFSF14) inhibits tumor growth via activating anti-tumor immune responses in 4T1 mouse mammary tumor model in immune competent syngeneic mice By feeds.nature.com Published On :: 2020-04-20 Full Article
re TMB: a promising immune-response biomarker, and potential spearhead in advancing targeted therapy trials By feeds.nature.com Published On :: 2020-04-28 Full Article
re UNC5B mediates G2/M phase arrest of bladder cancer cells by binding to CDC14A and P53 By feeds.nature.com Published On :: 2020-05-06 Full Article
re Author Correction: Quantum wave–particle superposition in a delayed-choice experiment By feeds.nature.com Published On :: 2020-04-28 Full Article
re Cardamonin protects against lipopolysaccharide-induced myocardial contractile dysfunction in mice through Nrf2-regulated mechanism By feeds.nature.com Published On :: 2020-04-21 Full Article
re Nintedanib inhibits keloid fibroblast functions by blocking the phosphorylation of multiple kinases and enhancing receptor internalization By feeds.nature.com Published On :: 2020-04-23 Full Article
re Diabetes downregulates peptide transporter 1 in the rat jejunum: possible involvement of cholate-induced FXR activation By feeds.nature.com Published On :: 2020-04-27 Full Article
re An in vitro Förster resonance energy transfer-based high-throughput screening assay identifies inhibitors of SUMOylation E2 Ubc9 By feeds.nature.com Published On :: 2020-04-27 Full Article
re Compound LM9, a novel MyD88 inhibitor, efficiently mitigates inflammatory responses and fibrosis in obesity-induced cardiomyopathy By feeds.nature.com Published On :: 2020-04-27 Full Article
re Head-to-head trials in inflammatory bowel disease: past, present and future By feeds.nature.com Published On :: 2020-04-17 Full Article
re Microbiota and colorectal cancer: colibactin makes its mark By feeds.nature.com Published On :: 2020-04-21 Full Article
re Colons or semi-colons: punctuating the regional variation of intestinal microbial–immune interactions By feeds.nature.com Published On :: 2020-04-22 Full Article
re Inducing senescence sensitizes pancreatic tumours to therapies By feeds.nature.com Published On :: 2020-04-28 Full Article
re Universal screening for hepatitis C virus infection should be linked to universal treatment access By feeds.nature.com Published On :: 2020-04-29 Full Article
re Author Correction: Management of IBD during the COVID-19 outbreak: resetting clinical priorities By feeds.nature.com Published On :: 2020-05-06 Full Article
re Effects of acute and repeated treatment with methocinnamox, a mu opioid receptor antagonist, on fentanyl self-administration in rhesus monkeys By feeds.nature.com Published On :: 2020-05-06 Full Article
re A novel multidimensional reinforcement task in mice elucidates sex-specific behavioral strategies By feeds.nature.com Published On :: 2020-05-06 Full Article
re Cannabinoid CB<sub>2</sub> receptors mediate the anxiolytic-like effects of monoacylglycerol lipase inhibition in a rat model of predator-induced fear By feeds.nature.com Published On :: 2020-05-06 Full Article
re A roadmap for development of neuro-oscillations as translational biomarkers for treatment development in neuropsychopharmacology By feeds.nature.com Published On :: 2020-05-06 Full Article
re Correction: Ketamine metabolites, clinical response, and gamma power in a randomized, placebo-controlled, crossover trial for treatment-resistant major depression By feeds.nature.com Published On :: 2020-05-06 Full Article
re Nesfatin-1 puts the brakes on reward-based feeding By feeds.nature.com Published On :: 2020-05-06 Full Article
re Evaluating the impact of trauma and PTSD on epigenetic prediction of lifespan and neural integrity By feeds.nature.com Published On :: 2020-05-07 Full Article
re Nuclear receptor crosstalk — defining the mechanisms for therapeutic innovation By feeds.nature.com Published On :: 2020-04-17 Full Article
re Author Correction: Insights into parathyroid hormone secretion By feeds.nature.com Published On :: 2020-04-20 Full Article
re Obesity and impaired metabolic health in patients with COVID-19 By feeds.nature.com Published On :: 2020-04-23 Full Article
re Author Correction: Vitamin lipid nanoparticles enable adoptive macrophage transfer for the treatment of multidrug-resistant bacterial sepsis By feeds.nature.com Published On :: 2020-04-28 Full Article
re Publisher Correction: Optomechanical detection of vibration modes of a single bacterium By feeds.nature.com Published On :: 2020-04-29 Full Article