li Coimbatore District Police arrest two men for robbing Kerala jeweller of ₹54 lakh By www.thehindu.com Published On :: Wed, 13 Nov 2024 19:29:30 +0530 Full Article Coimbatore
li Legal battle over permanent English teacher appointments in high school continues By www.thehindu.com Published On :: Wed, 13 Nov 2024 20:27:56 +0530 Govt cites financial problems; PSC rank-holders say posts are being created for other language subjects Full Article Kerala
li State Library Council Awards declared, M. Leelavathy wins I.V. Das award for overall contributions By www.thehindu.com Published On :: Wed, 13 Nov 2024 20:44:33 +0530 Full Article Kerala
li Supreme Court verdict on bulldozer demolitions: Jamiat hails verdict, victims seek compensation By www.thehindu.com Published On :: Wed, 13 Nov 2024 20:55:56 +0530 It is a significant step towards safeguarding the rule of law and fundamental rights of citizens, say Jamiat leaders Full Article India
li Food prices rising due to failed policies of Modi govt., says Congress By www.thehindu.com Published On :: Wed, 13 Nov 2024 21:03:46 +0530 Tomatoes, onions, and potatoes disappearing from common man’s plate, says Jairam Ramesh Full Article India
li Revise OBC creamy layer limit, say MPs at House panel meeting By www.thehindu.com Published On :: Wed, 13 Nov 2024 21:27:44 +0530 They say that many OBC candidates have been unable to join the Civil Services despite clearing the exam Full Article India
li Children’s Day: public meet, rally led by girls to be held in Thiruvananthapuram By www.thehindu.com Published On :: Wed, 13 Nov 2024 21:41:04 +0530 25,000 students from 200 schools will be part of the rally Full Article Kerala
li BJP’s win in recent polls is expression of people’s faith in govt. policies: Haryana Governor By www.thehindu.com Published On :: Thu, 14 Nov 2024 07:50:35 +0530 Full Article Haryana
li Use fog safety devices to ensure punctuality and safety of trains in winters: SCR GM By www.thehindu.com Published On :: Wed, 13 Nov 2024 14:13:21 +0530 Full Article Telangana
li Nirmal Municipality junior assistant in ACB net By www.thehindu.com Published On :: Wed, 13 Nov 2024 19:03:40 +0530 Full Article Telangana
li Govt. charges BRS with hatching conspiracies to stall development projects for political gains By www.thehindu.com Published On :: Wed, 13 Nov 2024 19:17:30 +0530 Dy CM says involvement of BRS leader in Lagacharla incident exposes the party’s intentions Full Article Telangana
li Indian households accumulated USD 9.7 trillion in wealth over last ten years: Morgan Stanley By www.newkerala.com Published On :: Wed, 13 Nov 2024 17:34:02 +0530 Full Article
li 'Any relief on bank guarantee will be provided across the sector': Scindia on Vodafone Idea request for waiver of bank guarantees for spectrum By www.newkerala.com Published On :: Wed, 13 Nov 2024 17:36:01 +0530 Full Article
li India IT spending to reach USD 160 billion in 2025 fueled by application and infrastructure software market growth: Gartner By www.newkerala.com Published On :: Wed, 13 Nov 2024 17:38:01 +0530 Full Article
li Public Sector Banks records strong performance in 1st half of FY25 By www.newkerala.com Published On :: Wed, 13 Nov 2024 17:50:02 +0530 Full Article
li India will continue to be vocal about climate finances at COP29 By www.newkerala.com Published On :: Wed, 13 Nov 2024 17:52:02 +0530 Full Article
li FSSAI discusses various sets of compliances with e-commerce food operators By www.newkerala.com Published On :: Wed, 13 Nov 2024 17:54:01 +0530 Full Article
li Centre to deliberate on plans to achieve 500 GW green energy target by 2030 By www.newkerala.com Published On :: Wed, 13 Nov 2024 18:02:02 +0530 Full Article
li LTIMindtree expands footprint in US with new innovation facility By www.newkerala.com Published On :: Wed, 13 Nov 2024 18:04:02 +0530 Full Article
li India set to become 'major producer' of electric vehicles like China: Mark Mobius By www.newkerala.com Published On :: Wed, 13 Nov 2024 18:50:02 +0530 Full Article
li Coal import for blending purposes in power generation declines by 8.5% during April-Sept 2024 By www.newkerala.com Published On :: Wed, 13 Nov 2024 19:02:02 +0530 Full Article
li An Efficient All-Visible Light-Activated Photoswitches Based on Diarylethenes and CdS Quantum Dots By pubs.rsc.org Published On :: Chem. Sci., 2024, Accepted ManuscriptDOI: 10.1039/D4SC06110A, Edge Article Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Kezhou Chen, Jiayi Liu, Joakim Andréasson, Bo Albinsson, Tiegen Liu, Lili HouAll-visible light-activated diarylethene (DAE) photoswitches are highly attractive for applications in smart photoresponsive materials. Photocyclization of DAE via the low-lying excited triplet state through triplet energy transfer (TET) from a...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
li Phase transition induced hydrogen activation for enhanced furfural reductive amination over CoCu bimetallic catalyst By pubs.rsc.org Published On :: Chem. Sci., 2024, Accepted ManuscriptDOI: 10.1039/D4SC05885B, Edge Article Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Yilin Wei, Zixu Ma, Beibei Liu, Jialin Yang, Dan Wu, Yongsheng Zhang, Yuexing Zhang, Charles Chunbao Xu, Renfeng NieThe synthesis of primary amines from renewable biomass and its derivatives through reductive amination has garnered significant attention. How to construct efficient non-noble-metal catalysts that enable low-temperature catalysis still remains...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
li Synthesis of highly condensed phospholes by Lewis acid-assisted dehydrogenative Mallory reaction under visible light irradiation By pubs.rsc.org Published On :: Chem. Sci., 2024, Accepted ManuscriptDOI: 10.1039/D4SC05657D, Edge Article Open Access This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Ikki Kamiyoshi, Yuki Kojima, Shibo Xu, Kosuke Yasui, Yuji Nishii, Koji HiranoA photo-promoted oxidative cyclization, that is, Mallory reaction of 2,3-diarylbenzophopholes has been developed. With an assistance of Bi(OTf)3 Lewis acid, the reaction proceeds smoothly under visible light irradiation even without...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
li Chandigarh's air quality continues to be worse than Punjab, Haryana By www.newkerala.com Published On :: Wed, 13 Nov 2024 18:22:02 +0530 Full Article
li Vistara's last flight from Odisha takes off for Delhi ahead of merger with Air India By www.newkerala.com Published On :: Wed, 13 Nov 2024 19:06:02 +0530 Full Article
li DRDO conducts maiden flight test of Long-Range Land Attack Cruise Missile (LRLACM) By www.newkerala.com Published On :: Wed, 13 Nov 2024 19:44:02 +0530 Full Article
li HC quashes magistrate court’s directive to register FIR against police officers By www.thehindu.com Published On :: Wed, 13 Nov 2024 19:36:51 +0530 Magistrate court’s order to file FIR against police officers, including IPS officer and former Malappuram Superintendent of Police Sujith Das, in connection with an alleged sexual assault case quashed Full Article Kerala
li Afghanistan attends U.N. climate talks for first time since Taliban return to power By www.thehindu.com Published On :: Wed, 13 Nov 2024 11:33:16 +0530 Afghanistan’s first delegation at United Nations climate talks since the Taliban’s return to power in 2021 has arrived in Baku, Azerbaijan Full Article Environment
li Fifth storm in a month bears down on the Philippines By www.thehindu.com Published On :: Wed, 13 Nov 2024 11:49:22 +0530 The local government also reported knee-high floods across Santiago, a city of 1,50,000 people along an upper bank of the Cagayan river Full Article Environment
li ‘Anti-war’ comedy play riles Bulgarian nationalists By www.thehindu.com Published On :: Wed, 13 Nov 2024 11:50:04 +0530 Last week’s premiere of Arms and the Man by renowned Irish-born playwright George Bernard Shaw sparked raucous protests by nationalist groups Full Article World
li Cold War-era H-6 bomber enhances China’s ability to strike U.S. bases By www.thehindu.com Published On :: Wed, 13 Nov 2024 12:14:26 +0530 The H-6 long-range bomber was used in China’s October war games around Taiwan; it flew close to the U.S. mainland for first time in June Full Article World
li COP29: India, other developing countries demand fair climate finance commitments By www.thehindu.com Published On :: Wed, 13 Nov 2024 13:33:21 +0530 India, LMDCs advocate for equitable climate finance at COP29, pushing for transparency, fairness, and flexibility in financial commitments Full Article Environment
li Iran executes in public a serial rapist convicted in dozens of cases By www.thehindu.com Published On :: Wed, 13 Nov 2024 14:43:02 +0530 Iran’s state media say authorities have executed in public a man convicted of raping dozens of women over two decades Full Article World
li Lebanon media claims Israeli strike hit apartment south of Beirut By www.thehindu.com Published On :: Wed, 13 Nov 2024 15:10:43 +0530 Israeli warplanes launched a strike at dawn targeting a residential apartment in a building in the Dawhet Full Article World
li IndiGo, Air India cancel flights to Bali following volcanic eruption By www.thehindu.com Published On :: Wed, 13 Nov 2024 17:23:06 +0530 The Mount Lewotobi Laki Laki volcano located in a remote island in East Nusa Tenggara province erupted earlier this month and has resulted in ash clouds Full Article India
li Sri Lanka to hold key parliamentary vote on November 14 By www.thehindu.com Published On :: Wed, 13 Nov 2024 20:35:59 +0530 President Anura Kumara Dissanayake’s ruling alliance is looking to secure a majority in Parliament Full Article World
li Indonesia and Australia hold joint military drills after signing a new defense agreement By www.thehindu.com Published On :: Wed, 13 Nov 2024 21:32:15 +0530 The Indonesian and Australian militaries are holding joint combat drills off Indonesia’s main island of Java with about 2,000 troops training in air, maritime, amphibious and land operations Full Article World
li New ATP-competitive inhibitors of E. coli GyrB obtained from the mapping of the hydrophobic floor at the binding site: synthesis and biological evaluation By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3759-3777DOI: 10.1039/D4MD00498A, Research ArticleLucas Gutierrez, Peter Peršolja, Rodrigo Tosso, Nace Zidar, Danijel Kikelj, Ricardo D. EnrizA diagram of the active site of E. coli gyrase B, highlighting the hydrophobic subsite, including key residues relevant to ligand binding.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
li Stachydrine, a pyrrole alkaloid with promising therapeutic potential against metabolic syndrome and associated organ dysfunction By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3652-3673DOI: 10.1039/D4MD00425F, Review ArticleSemim Akhtar Ahmed, Prasenjit Manna, Jagat Chandra BorahMetabolic syndrome is a multifaceted condition marked by interconnected risk factors, significantly increasing the risk of serious diseases like cardiovascular disease, type 2 diabetes, and stroke.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
li A photoswitchable CENP-E inhibitor with single blue-green light to control chromosome positioning in mitotic cells By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3795-3799DOI: 10.1039/D4MD00458B, Research ArticleKazuya Matsuo, Takashi Kikukawa, Tomonori Waku, Akio Kobori, Nobuyuki TamaokiA photoswitchable centromere-associated protein E (CENP-E) inhibitor based on the 4-methylaminoazobenzene photoswitch is reported, which is characterized with cis–trans photoisomerization with blue-green light and fast thermal relaxation.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
li Pyridinyl 4-(2-oxoalkylimidazolidin-1-yl)benzenesulfonates and their hydrochloride salts as novel water soluble antimitotic prodrugs bioactivated by cytochrome P450 1A1 in breast cancer cells By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3728-3745DOI: 10.1039/D4MD00476K, Research ArticleVincent Ouellette, Chahrazed Bouzriba, Atziri Corin Chavez Alvarez, Quentin Bruxelles, Geneviève Hamel-Côté, Sébastien FortinNew water soluble antimitotic CYP1A1-activated prodrugs named PYRAIB-SOs and their hydrochlorides targeting breast cancers.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
li Fexinidazole optimization: enhancing anti-leishmanial profile, metabolic stability and hERG safety By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3837-3852DOI: 10.1039/D4MD00426D, Research ArticleAbdrrahman Shemsu Surur, Chin Fung Chan, Frieda-Marie Bartz, Iris L. K. Wong, Van T. D. Nguyen, Lukas Schulig, Andreas Link, Tak Hang Chan, Larry M. C. Chow, Patrick J. BednarskiStructure-guided optimization of fexinidazole led to analog (S)-51, a promising lead compound with superior activity, improved metabolic stability, and enhanced hERG safetyThe content of this RSS Feed (c) The Royal Society of Chemistry Full Article
li Design and synthesis of novel multi-target tetrabromophthalimides as CBS and Topo-II inhibitors and DNA intercalators By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3800-3816DOI: 10.1039/D4MD00585F, Research ArticleMarwa Abdel-Motaal, Dalal Ali Aldakhili, Ayman B. Farag, Ayman Abo Elmaaty, Marwa Sharaky, Nadia A. Mohamed, Saad Shaaban, Abdullah Yahya Abdullah Alzahrani, Ahmed A. Al-KarmalawyNovel multi-target tetrabromophthalimides as CBS and Topo-II inhibitors and DNA intercalators.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
li Novel PROTAC probes targeting KDM3 degradation to eliminate colorectal cancer stem cells through inhibition of Wnt/β-catenin signaling By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3746-3758DOI: 10.1039/D4MD00122B, Research Article Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Shadid U. Zaman, Piyusha P. Pagare, Hongguang Ma, Rosalie G. Hoyle, Yan Zhang, Jiong LiWe designed and synthesized novel IOX1-based PROTACs, which can selectively degrade KDM3A and KDM3B to eliminate colorectal cancer stem cells through inhibition of Wnt signaling.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
li Evaluating the therapeutic potential of genetically engineered probiotic Zbiotics (ZB183) for non-alcoholic steatohepatitis (NASH) management via modulation of the cGAS-STING pathway By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3817-3836DOI: 10.1039/D4MD00477A, Research ArticleMaha Saad, Walaa Ibrahim, Amany Helmy Hasanin, Aya Magdy Elyamany, Marwa MatboliZBiotics administration in the NASH model downregulated the RNA panel (MAPK3, EDN1, TNF, miR-6888-5p, lncRNA RABGAP1L-DT-206), restored intestinal barrier integrity, reduced hepatic inflammation, and improved lipid profiles and liver enzymes.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
li Hydrophobic CPP/HDO conjugates: a new frontier in oligonucleotide-warheaded PROTAC delivery By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3695-3703DOI: 10.1039/D4MD00546E, Research ArticleMiyako Naganuma, Nobumichi Ohoka, Motoharu Hirano, Daishi Watanabe, Genichiro Tsuji, Takao Inoue, Yosuke DemizuA novel hydrophobic cell-penetrating peptide (CPP) and heteroduplex oligonucleotide (HDO)-conjugated PROTAC, CPP/HDO-PROTAC, was designed to enhance its intracellular delivery and degradation efficiency.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
li Anticancer potential of copper(I) complexes based on isopropyl ester derivatives of bis(pyrazol-1-yl)acetate ligands By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4MD00610K, Research Article Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Maura Pellei, Carlo Santini, Miriam Caviglia, Jo' Del Gobbo, Chiara Battocchio, Carlo Meneghini, Simone Amatori, Chiara Donati, Eleonora Zampieri, Valentina Gandin, Cristina MarzanoIn this paper, the isopropyl ester derivatives LOiPr and L2OiPr of bis(pyrazol-1-yl)acetic acid and bis(3,5-dimethyl-pyrazol-1-yl)acetic acid were used as chelators for the preparation of the new Cu(I) phosphane complexes 1-4....The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
li Advances in Detecting Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) Using Molecular Receptors and Nanostructured Assemblies By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4MD00661E, Review ArticleAvijit Kumar DasThe detection and quantification of non-steroidal anti-inflammatory drugs (NSAIDs) are crucial due to their widespread use and potential impact on human health and the environment. This review provides a comprehensive...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
li IIT Madras to conduct two-day summit on extended reality By www.thehindu.com Published On :: Wed, 13 Nov 2024 13:19:23 +0530 The aim is to develop academic partnership programmes to boost research in XR or extended reality Full Article Chennai
