Latest k news

[ASAP] Combined Peptide and Small-Molecule Approach toward Nonacidic THIQ Inhibitors of the KEAP1/NRF2 Interaction

By feedproxy.google.com
Published On :: Fri, 10 Apr 2020 04:00:00 GMT

ACS Medicinal Chemistry Letters

DOI: 10.1021/acsmedchemlett.9b00594

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[ASAP] New Dual CK2/HDAC1 Inhibitors with Nanomolar Inhibitory Activity against Both Enzymes

By feedproxy.google.com
Published On :: Fri, 10 Apr 2020 04:00:00 GMT

ACS Medicinal Chemistry Letters

DOI: 10.1021/acsmedchemlett.9b00561

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[ASAP] Discovery of an Atropisomeric PI3Kß Selective Inhibitor through Optimization of the Hinge Binding Motif

By feedproxy.google.com
Published On :: Wed, 15 Apr 2020 04:00:00 GMT

ACS Medicinal Chemistry Letters

DOI: 10.1021/acsmedchemlett.0c00095

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[ASAP] Can Drug Repositioning Work as a Systematical Business Model?

By feedproxy.google.com
Published On :: Fri, 17 Apr 2020 04:00:00 GMT

ACS Medicinal Chemistry Letters

DOI: 10.1021/acsmedchemlett.0c00122

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[ASAP] PROTAC Compounds Targeting a-Synuclein Protein for Treating Neurogenerative Disorders: Alzheimer’s and Parkinson’s Diseases

By feedproxy.google.com
Published On :: Tue, 28 Apr 2020 04:00:00 GMT

ACS Medicinal Chemistry Letters

DOI: 10.1021/acsmedchemlett.0c00192

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[ASAP] Scaffold Repurposing of in-House Chemical Library toward the Identification of New Casein Kinase 1 d Inhibitors

By feedproxy.google.com
Published On :: Mon, 04 May 2020 04:00:00 GMT

ACS Medicinal Chemistry Letters

DOI: 10.1021/acsmedchemlett.0c00028

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[ASAP] De-risking Drug Discovery of Intracellular Targeting Peptides: Screening Strategies to Eliminate False-Positive Hits

By feedproxy.google.com
Published On :: Tue, 05 May 2020 04:00:00 GMT

ACS Medicinal Chemistry Letters

DOI: 10.1021/acsmedchemlett.0c00022

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Germany Facing Mass Blackouts Because The Wind And Solar Won’t Cooperate

By latestsolarnews.com
Published On :: Sat, 04 Mar 2017 19:59:09 +0000

Germany’s energy network nearly broken down in January because of poor execution from wind turbines and sun based boards, as indicated by information from a noteworthy exchange union. Wind and sunlight based power plants failed to meet expectations in January, 2017, as a result of shady climate with almost no wind, setting the phase for …

The post Germany Facing Mass Blackouts Because The Wind And Solar Won’t Cooperate appeared first on LatestSolarNews.

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News

Solar Trees Powering The Park Of South Florida

By latestsolarnews.com
Published On :: Sun, 23 Jul 2017 23:58:07 +0000

Joining South Florida’s lush, green canopy of real trees are a new crop of solar trees. These “trees” have blue trunks and bear no fruit, but supply clean energy to whoever needs it. If you’re at the beach and your phone starts to die, you can charge it right here using Solar Power. Here’s how …

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News

4 Benefits Of Solar LED Lights For Parking Lots

By latestsolarnews.com
Published On :: Sun, 08 Jul 2018 21:32:34 +0000

The future is solar LED lights. You will see them in the parking lots and other large areas around a city. They are cheap and save a good deal of money on electricity bills. Nowadays, the majority of parking lots feature the conventional lights that get their power from the grid. These products are not …

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Power Generation

Ugly Duckling Presse

By uglyducklingpresse.org
Published On ::

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Moving to Jekyll

By simurai.com
Published On :: Sun, 02 Feb 2014 00:00:00 +0000

I haven’t redesigned my site for years, can’t even remember exactly. Also, haven’t been posting for a while. So as a New Year’s resolution I redid my site using Jekyll and am hosting it as a GitHub page.

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FrontLinks

By simurai.com
Published On :: Wed, 01 Oct 2014 00:00:00 +0000

This is my (living) collection of front-end links. It’s not complete by all means, in fact, there isn’t any of the obvious ones, like Can I use or so. Just some links that I need occasionally but can’t remember their names, so I saved them here for quick access. Also, they’re somewhat randomly ordered.

Note to self: Edit source

Docs

HTML reference
DevDocs
Native HTML Elements
jQuery -> JS
Default Font Family
Shadow DOM
- The list
- Form Pseudo Elements
Device sizes
SVG PocketGuide

CSS

CSS reference
All CSS properties
All CSS values
CSS Triggers (perf)
Stats
- StyleStats
- CSS Stats
CSS Preprocessors
- Roole
- CSS to SCSS
FlexBox
Animation
- Bounce.js
- Stylie
Easing:
nth-child
- nth-test
- :kids
Color
- Color converter
- Contrast tester
Clip Path
px to em
Cursors
Live Edit
- Takana
- Emmet

Libs + Frameworks

Utils + Tools

Wireframes
HTML symbols
- ☺ Characters
- Draw Chars
Placeholder Image
FavIcon Editor
SVG
- SVG Optimizer
- Paths (editor)
GitHub Editor

Resources

Color schemes
Fonts
Icons
- Feather
- Icomoon
- Material
- Entypo
Photos
Subtle Patterns
UI Sounds

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Back to the :roots

By simurai.com
Published On :: Wed, 09 Sep 2015 00:00:00 +0000

The cascade in CSS is a curse and blessing at the same time. It usually works quite well, but there are issues that let people get all worked up and ask the question Do We Even Need CSS Anymore. I can somewhat relate to that - but I also think it’s not the cascade alone and also about fighting specificity. Not running into issues with specificity is hard. Almost as hard as pronouncing that word.

In this post I’ll try to show a few ways how you can make the cascade be your friend and maybe reduce the need of overriding and thus encounter less fighting with specificity.

Tip 1:

For every CSS property that you write, try to move it up the tree as far as possible. In other words: Back to the :root.

For example, our site has a side bar and we want to add a short bio to it. The markup might look something like this:

<body>
	<main class=“Posts”>
	<aside class=“SideBar”>
		<nav class=“Nav”>
		<p class=“Bio”>

And the CSS:

.Bio {
	font-size: .8em;
	line-height: 1.5;
	color: #888;
}

That would work. But if we look at the Nav that is already in the SideBar, chances are good that some of the styles are the same. In our case it’s font-size and color. So let’s remove those properties from Nav and Bio and add it to the shared parent element, the SideBar.

.SideBar {
	font-size: .8em;
	color: #888;
}

And as it turns out, that line-height: 1.5; is already defined for our Posts. So since it seems that the whole page uses the same line-height, let’s remove it from the Bio and Post elements and move it all up to the root node.

:root {
	line-height: 1.5;
}

This probably sounds like common sense, but often it’s tempting to just style your new thing without even looking if some of the sibling elements define the same thing. This also happens when you copy&paste styles from another section or when pasting some snippets you found online. It might take a bit more time to refactor and seems scary, but it should keep our CSS in a healthier state.

Style the branches, not each leaf

Tip 2:

Style certain properties always as a combo.

A good example is the color and background-color combo. Unless you make only small tweaks, it’s probably a good idea to always change them together. When adding a background color to an element, it might not contain any text, but probably some child will. Therefore if we set foreground and background color together, we can always be sure we won’t run into any legibility and contrast issues. Also, next time we change a background color, we don’t have to hunt for all the text colors that need to be changed too, it’s right there in the same place.

Screenshot from Colorable

Tip 3:

Use “dynamic” values, such as currentColor and ems.

Sometimes it might make sense to use the text color for other properties. Like for border, box-shadow or for the fill of SVG icons. Instead of defining them directly you can use currentColor and it will be the same the color property. And since color inherits by default, you might can change it in only one place.

Similarly ems are mapped to font-size allowing you to scale everything by just changing the :root font size.

Here a few more details on currentColor and EMs.

Tip 4:

Override UA Styles to inherit from its parents.

Form controls like buttons, inputs get styled by the browser in a certain way. Overriding them with inherit makes them adapt to your own styles.

button,
input,
select,
textarea {
	color: inherit;
	font-family: inherit;
	font-style: inherit;
	font-weight: inherit;
}

The example above is taken from sanitize.css. normalize.css does the same, so if you use them, you’re already covered.

You can also try to restyle other inputs like a range slider, radio, checkbox etc. And as seen above, by using currentColor, make them automatically match the color property. And maybe move them from a light into a dark theme without changing anything.

Conclusion

That’s all nice stuff, but who is it for? Well, of course it can’t be forced upon every situation. I would say small and simple web sites benefit the most. But even when using a preprocessor, it might not hurt if it reduces the amount of CSS that gets output or when a few variables aren’t even needed.

Also it seems suited for the “single purpose class” approach like Tachyons. It might reduce complexity and the amount of classes that are needed.

Another interesting thing could be the upcoming custom properties a.k.a. CSS variables. Unlike variables in preprocessors, when overriding a custom property, it will only affect the current selector scope. So in a sense they will be “cascading variables”. But I still have to try that out and see how it works in practice.

ps. It is possible that this post is inspired by this tweet.

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Unlock Your Team’s Potential With Teamstack

By www.webdesignerdepot.com
Published On :: Tue, 21 Apr 2020 10:45:38 +0000

Teamstack is a password manager for your whole team. Running in the cloud it allows you to manage your tools and resources, and seamlessly scale your teams’ access, from a single, easy-to-use control panel. Teamstack is powerful, and secure with multi-factor authentication, single sign-in, SAML and form-based authentication. It works with desktop and mobile apps, […]

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Popular Design News of the Week: April 20, 2020 – April 26, 2020

By www.webdesignerdepot.com
Published On :: Sun, 26 Apr 2020 10:45:05 +0000

Every week users submit a lot of interesting stuff on our sister site Webdesigner News, highlighting great content from around the web that can be of interest to web designers. The best way to keep track of all the great stories and news being posted is simply to check out the Webdesigner News site, however, […]

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Popular Design News of the Week: April 27, 2020 – May 3, 2020

By www.webdesignerdepot.com
Published On :: Sun, 03 May 2020 10:45:45 +0000

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Thanks to Covid-19, Website Accessibility Has Never Been More Important

By www.webdesignerdepot.com
Published On :: Thu, 07 May 2020 10:45:59 +0000

The first global pandemic of the digital era is upon us. We’re living in unprecedented and uncomfortable times. For our senior citizens, these past several weeks have been particularly discomforting. According to the CDC, men and women over the age of 65 are significantly more likely to develop complications from COVID-19. As we seek to […]

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Interactive Design
a11y
design for seniors
older web users
web design for elderly
website accessibility

Women’s squad raises ₹20 lakh

By www.thehindu.com
Published On :: Mon, 04 May 2020 23:17:41 +0530

The Indian women’s hockey team’s efforts to crowd-fund support for poor and migrant workers has raised ₹20,01,130 through an 18-day online challenge.T

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Sport

Hockey | HI asks for bids to host various Nationals

By www.thehindu.com
Published On :: Tue, 05 May 2020 22:53:48 +0530

State units can take part across age-groups

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Hockey

The matter of photography in the Americas / Natalia Brizuela and Jodi Roberts ; with contributions by Lisa Blackmore, Amy Sara Carroll, Marianela D'Aprile, María Fernanda Domínguez, Heloisa Espada, Rachel Price, Diana Ruiz, Tatiane Santa Ro

By library.mit.edu
Published On :: Sun, 16 Feb 2020 06:00:01 EST

Rotch Library - TR184.B75 2018

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Design: the key concepts / D.J. Huppatz

By library.mit.edu
Published On :: Sun, 16 Feb 2020 06:00:01 EST

Barker Library - NK1510.H87 2019

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How art can be thought: a handbook for change / Allan deSouza

By library.mit.edu
Published On :: Sun, 16 Feb 2020 06:00:01 EST

Rotch Library - N7425.D459 2018

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The women of Atelier 17: modernist printmaking in midcentury New York / Christina Weyl

By library.mit.edu
Published On :: Sun, 16 Feb 2020 06:00:01 EST

Rotch Library - NE538.N5 W49 2019

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Huguette Caland / edited by Anne Barlow, Sara Matson and Giles Jackson ; texts by Anne Barlow, Brigitte Caland and Negar Azimi

By library.mit.edu
Published On :: Sun, 16 Feb 2020 06:00:01 EST

Rotch Library - N6537.C329 A4 2019

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Legacy of the masters: painting and calligraphy of the Islamic world from the Shavleyan family collection / Will Kwiatkowski ; with contributions by John Seyller

By library.mit.edu
Published On :: Sun, 16 Feb 2020 06:00:01 EST

Rotch Library - N6260.K87 2019

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