in Screening for Glucose Perturbations and Risk Factor Management in Dysglycemic Patients With Coronary Artery Disease--A Persistent Challenge in Need of Substantial Improvement: A Report From ESC EORP EUROASPIRE V By care.diabetesjournals.org Published On :: 2020-03-20T11:50:34-07:00 OBJECTIVE Dysglycemia, in this survey defined as impaired glucose tolerance (IGT) or type 2 diabetes, is common in patients with coronary artery disease (CAD) and associated with an unfavorable prognosis. This European survey investigated dysglycemia screening and risk factor management of patients with CAD in relation to standards of European guidelines for cardiovascular subjects. RESEARCH DESIGN AND METHODS The European Society of Cardiology’s European Observational Research Programme (ESC EORP) European Action on Secondary and Primary Prevention by Intervention to Reduce Events (EUROASPIRE) V (2016–2017) included 8,261 CAD patients, aged 18–80 years, from 27 countries. If the glycemic state was unknown, patients underwent an oral glucose tolerance test (OGTT) and measurement of glycated hemoglobin A1c. Lifestyle, risk factors, and pharmacological management were investigated. RESULTS A total of 2,452 patients (29.7%) had known diabetes. OGTT was performed in 4,440 patients with unknown glycemic state, of whom 41.1% were dysglycemic. Without the OGTT, 30% of patients with type 2 diabetes and 70% of those with IGT would not have been detected. The presence of dysglycemia almost doubled from that self-reported to the true proportion after screening. Only approximately one-third of all coronary patients had completely normal glucose metabolism. Of patients with known diabetes, 31% had been advised to attend a diabetes clinic, and only 24% attended. Only 58% of dysglycemic patients were prescribed all cardioprotective drugs, and use of sodium–glucose cotransporter 2 inhibitors (3%) or glucagon-like peptide 1 receptor agonists (1%) was small. CONCLUSIONS Urgent action is required for both screening and management of patients with CAD and dysglycemia, in the expectation of a substantial reduction in risk of further cardiovascular events and in complications of diabetes, as well as longer life expectancy. Full Article
in Glucosamine Use, Inflammation, and Genetic Susceptibility, and Incidence of Type 2 Diabetes: A Prospective Study in UK Biobank By care.diabetesjournals.org Published On :: 2020-03-20T11:50:34-07:00 OBJECTIVE Glucosamine is a widely used supplement typically taken for osteoarthritis and joint pain. Emerging evidence suggests potential links of glucosamine with glucose metabolism, inflammation, and cardiometabolic risk. We prospectively analyzed the association of habitual glucosamine use with risk of type 2 diabetes (T2D) and assessed whether genetic susceptibility and inflammation status might modify the association. RESEARCH DESIGN AND METHODS This study analyzed 404,508 participants from the UK Biobank who were free of diabetes, cancer, or cardiovascular disease at baseline and completed the questionnaire on supplement use. Cox proportional hazards models were used to evaluate the association between habitual use of glucosamine and risk of incident T2D. RESULTS During a median of 8.1 years of follow-up, 7,228 incident cases of T2D were documented. Glucosamine use was associated with a significantly lower risk of T2D (hazard ratio 0.83, 95% CI 0.78–0.89) after adjustment for age, sex, BMI, race, center, Townsend deprivation index, lifestyle factors, history of disease, and other supplement use. This inverse association was more pronounced in participants with a higher blood level of baseline C-reactive protein than in those with a lower level of this inflammation marker (P-interaction = 0.02). A genetic risk score for T2D did not modify this association (P-interaction = 0.99). CONCLUSIONS Our findings indicate that glucosamine use is associated with a lower risk of incident T2D. Full Article
in Targeting CXCR1/2 Does Not Improve Insulin Secretion After Pancreatic Islet Transplantation: A Phase 3, Double-Blind, Randomized, Placebo-Controlled Trial in Type 1 Diabetes By care.diabetesjournals.org Published On :: 2020-03-20T11:50:34-07:00 OBJECTIVE Reparixin is an inhibitor of CXCR1/2 chemokine receptor shown to be an effective anti-inflammatory adjuvant in a pilot clinical trial in allotransplant recipients. RESEARCH DESIGN AND METHODS A phase 3, multicenter, randomized, double-blind, parallel-assignment study (NCT01817959) was conducted in recipients of islet allotransplants randomized (2:1) to reparixin or placebo in addition to immunosuppression. Primary outcome was the area under the curve (AUC) for C-peptide during the mixed-meal tolerance test at day 75 ± 5 after the first and day 365 ± 14 after the last transplant. Secondary end points included insulin independence and standard measures of glycemic control. RESULTS The intention-to-treat analysis did not show a significant difference in C-peptide AUC at both day 75 (27 on reparixin vs. 18 on placebo, P = 0.99) and day 365 (24 on reparixin vs. 15 on placebo, P = 0.71). There was no statistically significant difference between treatment groups at any time point for any secondary variable. Analysis of patient subsets showed a trend for a higher percentage of subjects retaining insulin independence for 1 year after a single islet infusion in patients receiving reparixin as compared with patients receiving placebo (26.7% vs. 0%, P = 0.09) when antithymocyte globulin was used as induction immunosuppression. CONCLUSIONS In this first double-blind randomized trial, islet transplantation data obtained with reparixin do not support a role of CXCR1/2 inhibition in preventing islet inflammation-mediated damage. Full Article
in What math professors and k-12 teachers think of each other By blogs.ams.org Published On :: Mon, 18 Nov 2019 14:00:32 +0000 By Michael Pershan, St. Ann’s School I. What do primary/secondary math educators think of the teaching that happens in colleges? And — the other way around — what do mathematics professors think of primary and secondary math teaching? I’m nearing … Continue reading → Full Article Communication Graduate Education K-12 Education
in The Dysfunction of Functions in Abstract Algebra By blogs.ams.org Published On :: Thu, 21 Nov 2019 12:00:56 +0000 Kathleen Melhuish & Kristen Lew Texas State University “[Functions] are completely different, which is what makes this course so challenging.” – Abstract Algebra Student Functions are hard for students, even students in abstract algebra courses. Even if students have seen … Continue reading → Full Article testing
in Teaching math in prison By blogs.ams.org Published On :: Thu, 06 Feb 2020 15:56:09 +0000 By: Kristin Pfabe, Nebraska Wesleyan University “I am sad this class is going to be over,” said one student. “What am I going to do with myself?” asked another during the last week of an Intermediate Algebra class that I … Continue reading → Full Article Faculty Experiences Prison
in Help! I need to teach my course online and I’ve never done this before By blogs.ams.org Published On :: Mon, 16 Mar 2020 16:05:52 +0000 By: Yvonne Lai, University of Nebraska-Lincoln Ray Levy, Mathematical Association of America This is cross-posted in MathValues and Abbe Herzig has written a companion post. Additional resources and future meetings are also available here: https://tinyurl.com/OnlineTalkshop. In times of crisis we … Continue reading → Full Article Faculty Experiences Online Education
in Surprise! Transitioning to online teaching By blogs.ams.org Published On :: Mon, 16 Mar 2020 19:17:51 +0000 By Abbe Herzig, AMS Director of Education Many of us are experiencing stress as schools, colleges and universities move instruction out of the classroom. Fortunately, even if distance learning is new to you, it isn’t new, and there is a … Continue reading → Full Article Classroom Practices Communication Faculty Experiences Mathematics Education Research Online Education Distance Learning education Mathematics Education
in Online learning in the time of Coronavirus: Tips for students and the instructors who support them By blogs.ams.org Published On :: Mon, 30 Mar 2020 10:00:26 +0000 Abbe Herzig, AMS Director of Education In the midst of the upheaval due to the Coronavirus, students and faculty are transitioning to new virtual classrooms. Many of us haven’t chosen to learn or teach, but here we are, making the … Continue reading → Full Article Graduate Education Mathematics Education Research Online Education Student Experiences education Mathematics Education online learning
in Square peg in an octagonal hole By blogs.ams.org Published On :: Tue, 14 Apr 2020 14:48:56 +0000 Interview with Ari Nieh, with commentary from Yvonne Lai Like many of us, I began teaching online this Spring. Unlike many of us, I began doing so at the start of the semester. I am co-teaching a class at Michigan … Continue reading → Full Article testing
in Starting Earlier on Lifelong Learning By blogs.ams.org Published On :: Fri, 01 May 2020 07:00:56 +0000 By: Matt Stamps, Yale-NUS College When Yale-NUS College reviewed the curriculum for its Mathematical, Computational, and Statistical (MCS) Sciences major in the autumn of 2018, I spent several weeks reading about mathematics programs at similar institutions. A common learning objective … Continue reading → Full Article testing
in Soccer: Germany's Bundesliga approved to return in mid-May By www.upi.com Published On :: Wed, 06 May 2020 12:13:09 -0400 The Bundesliga -- Germany's top soccer league -- will be allowed to resume in May after German Chancellor Angela Merkel lifted some lockdown restrictions in the country on Wednesday amid the coronavirus pandemic. Full Article
in Dallas Cowboys sign former first-round pick Cameron Erving By www.upi.com Published On :: Wed, 06 May 2020 19:14:49 -0400 The Dallas Cowboys agreed to terms with free-agent offensive lineman Cameron Erving, the team announced Wednesday. Full Article
in Cleveland Cavaliers planning to reopen training facility Friday By www.upi.com Published On :: Wed, 06 May 2020 21:52:33 -0400 The Cleveland Cavaliers are planning to reopen their training facility for limited individual workouts amid the coronavirus pandemic. Full Article
in Taiwan baseball league to allow fans back in ballparks amid pandemic By www.upi.com Published On :: Wed, 06 May 2020 23:05:02 -0400 A limited number of fans will be allowed to enter ballparks for games in Taiwan for the first time this season as stay-at-home orders continue to loosen amid the coronavirus pandemic. Full Article
in NFL lays out protocols for reopening of team facilities By www.upi.com Published On :: Wed, 06 May 2020 23:33:40 -0400 The NFL outlined protocols Wednesday for the gradual reopening of team facilities amid the coronavirus pandemic. Full Article
in Ex-MLB players in spotlight as world turns to Asia for baseball By www.upi.com Published On :: Thu, 07 May 2020 03:00:08 -0400 Playing in Taiwan once was a last option Justin Nicolino had to continue a professional baseball career. Now the former Miami Marlins pitcher is one of many ex-MLB players who provide entertainment for U.S. sports fans. Full Article
in Soccer: Bundesliga return includes Dortmund on May 16, Bayern Munich, May 17 By www.upi.com Published On :: Thu, 07 May 2020 11:22:58 -0400 The German Bundesliga released its full soccer schedule Thursday after German officials announced that the league is allowed to resume games after they were suspended due to the coronavirus pandemic. Full Article
in Weekend live sports include UFC 249, 14 baseball games in Asia By www.upi.com Published On :: Fri, 08 May 2020 03:00:10 -0400 UFC 249 will be sandwiched between 14 live baseball broadcasts out of South Korea and Taiwan this weekend for American sports fans to watch as they wait for major sports leagues to return. Full Article
in Peyton Manning trash talks Tom Brady before May 24 golf match By www.upi.com Published On :: Fri, 08 May 2020 07:59:36 -0400 Former star quarterback Peyton Manning delivered some trash talk to Tampa Bay Buccaneers star Tom Brady while they promoted their May 24 charity golf match. Full Article
in Korea's K-League soccer returns with rules against spitting, talking By www.upi.com Published On :: Fri, 08 May 2020 10:49:47 -0400 K-League soccer resumed with a game behind closed doors Friday in South Korea, with players prohibited from spitting and talking. Full Article
in Japan offers weekend's only top-level event as horse racing struggles to resume By www.upi.com Published On :: Fri, 08 May 2020 11:10:39 -0400 Coronavirus brings worldwide horse racing almost to a halt, with only one Grade 1 event on the weekend schedule, but rays of hope exist. Full Article
in New Orleans Saints release Pro Bowl OL Larry Warford By www.upi.com Published On :: Fri, 08 May 2020 18:46:39 -0400 The New Orleans Saints released Pro Bowl offensive lineman Larry Warford after three seasons, the team announced Friday. Full Article
in Smartphone-Based Glucose Monitors and Applications in the Management of Diabetes: An Overview of 10 Salient "Apps" and a Novel Smartphone-Connected Blood Glucose Monitor By clinical.diabetesjournals.org Published On :: 2012-10-01 Joseph TranOct 1, 2012; 30:173-178Practical Pointers Full Article
in Diabetes in the Emergency Department: Acute Care of Diabetes Patients By clinical.diabetesjournals.org Published On :: 2011-04-01 Candace D. McNaughtonApr 1, 2011; 29:51-59Feature Articles Full Article
in Elevated Liver Function Tests in Type 2 Diabetes By clinical.diabetesjournals.org Published On :: 2005-07-01 Elizabeth H. HarrisJul 1, 2005; 23:115-119Feature Articles Full Article
in Opportunities and Challenges for Biosimilars: What's on the Horizon in the Global Insulin Market? By clinical.diabetesjournals.org Published On :: 2012-10-01 Lisa S. RotensteinOct 1, 2012; 30:138-150Features Full Article
in Case Study: A 43-Year-Old Man With Perineal Pain and Swelling By clinical.diabetesjournals.org Published On :: 2001-10-01 David J. MeierOct 1, 2001; 19:Case Studies Full Article
in Case Study: Renal Disease in Type 1 Diabetes By clinical.diabetesjournals.org Published On :: 2001-04-01 William H. HermanApr 1, 2001; 19:Case Studies Full Article
in Insulin Therapy: A Personal Approach By clinical.diabetesjournals.org Published On :: 2015-07-01 Mayer B. DavidsonJul 1, 2015; 33:123-135Feature Articles Full Article
in Injecting Insulin: Taking shots safely, correctly, and with little or no pain By clinical.diabetesjournals.org Published On :: 2013-01-01 Jan 1, 2013; 31:46-46Patient Information Full Article
in Type 2 Diabetes in Children and Young Adults: A "New Epidemic" By clinical.diabetesjournals.org Published On :: 2002-10-01 Francine Ratner KaufmanOct 1, 2002; 20:President's Pen Full Article
in Food, Culture, and Diabetes in the United States By clinical.diabetesjournals.org Published On :: 2004-10-01 Karmeen D. KulkarniOct 1, 2004; 22:190-192Practical Pointers Full Article
in International Classification of Diseases, 10th Revision, Coding for Diabetes By clinical.diabetesjournals.org Published On :: 2017-10-01 Joy DuganOct 1, 2017; 35:232-238Practical Pointers Full Article
in Treatment of Onychomycosis in Diabetic Patients By clinical.diabetesjournals.org Published On :: 2006-10-01 Jason A. WinstonOct 1, 2006; 24:160-166Feature Articles Full Article
in A 52-Year-Old Woman With Hypertension and Diabetes Who Presents With Chest Pain By clinical.diabetesjournals.org Published On :: 2007-07-01 George D. HarrisJul 1, 2007; 25:115-118Case Studies Full Article
in Hypoglycemia in Type 1 and Type 2 Diabetes: Physiology, Pathophysiology, and Management By clinical.diabetesjournals.org Published On :: 2006-07-01 Vanessa J. BriscoeJul 1, 2006; 24:115-121Feature Articles Full Article
in Improving Patient Adherence By clinical.diabetesjournals.org Published On :: 2006-04-01 Alan M. DelamaterApr 1, 2006; 24:71-77Feature Articles Full Article
in A Review of the Pathophysiology, Classification, and Treatment of Foot Ulcers in Diabetic Patients By clinical.diabetesjournals.org Published On :: 2009-03-01 Warren ClaytonMar 1, 2009; 27:52-58Features Full Article
in Treatment Approach to Patients With Severe Insulin Resistance By clinical.diabetesjournals.org Published On :: 2016-04-01 Timothy J. ChurchApr 1, 2016; 34:97-104Feature Articles Full Article
in Self-Monitoring of Blood Glucose: The Basics By clinical.diabetesjournals.org Published On :: 2002-01-01 Evan M. BenjaminJan 1, 2002; 20:Practical Pointers Full Article
in Standards of Medical Care in Diabetes--2018 Abridged for Primary Care Providers By clinical.diabetesjournals.org Published On :: 2018-01-01 American Diabetes AssociationJan 1, 2018; 36:14-37Position Statements Full Article
in Case Study: Treating Hypertension in Patients With Diabetes By clinical.diabetesjournals.org Published On :: 2004-07-01 Evan M. BenjaminJul 1, 2004; 22:137-138Case Studies Full Article
in Good to Know: Factors Affecting Blood Glucose By clinical.diabetesjournals.org Published On :: 2018-04-01 Apr 1, 2018; 36:202-202Patient Education Full Article
in Using U-500 Insulin By clinical.diabetesjournals.org Published On :: 2012-04-01 Apr 1, 2012; 30:86-86Patient Information Full Article
in Inpatient Management of Hyperglycemia and Diabetes By clinical.diabetesjournals.org Published On :: 2011-01-01 Vasudev MagajiJan 1, 2011; 29:3-9Feature Articles Full Article
in Case Study: Diabetic Ketoacidosis in Type 2 Diabetes: "Look Under the Sheets" By clinical.diabetesjournals.org Published On :: 2004-10-01 Brian J. WelchOct 1, 2004; 22:198-200Case Studies Full Article
in Diabetes and Your Joints By clinical.diabetesjournals.org Published On :: 2001-07-01 Jul 1, 2001; 19:Patient Information Full Article
in Obesity in America: It's Getting Worse By clinical.diabetesjournals.org Published On :: 2004-01-01 Jennifer B. MarksJan 1, 2004; 22:Editorials Full Article
in The Disparate Impact of Diabetes on Racial/Ethnic Minority Populations By clinical.diabetesjournals.org Published On :: 2012-07-01 Edward A. ChowJul 1, 2012; 30:130-133Diabetes Advocacy Full Article
