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A quest to drug the undruggable

Listen to the latest Stereo Chemistry episode that explores why certain drug targets are so vexing, and the cutting edge approaches chemists are taking to finally crack them




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Oil and gas wastewater is a cheap fix for road dust but comes at a toxic cost

Treating roads with the wastewater may pollute the environment with radium and oil and gas compounds




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Volunteer service award to Carolyn Ribes

Chemist honored for her tireless efforts on behalf of diversity, inclusion, and volunteerism in the society




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Novacap to enter the U.S. by acquiring PCI Synthesis

French pharmaceutical services firm is latest to move into the U.S.




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Indorama pushes into Egypt with PET acquisition




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Expanding the glucose meter’s repertoire

Molecular logic gates allow personal glucose meters to respond to many other targets




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Oil and gas wastewater is a cheap fix for road dust, but it comes at a toxic cost

Treating roads with wastewater may pollute the environment with radium




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Topological materials move from the world of theoretical physics to experimental chemistry

These exotic materials could find applications in electronics, catalysis, and quantum computing




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LyondellBasell in talks to buy stake in Braskem

A deal would give LyondellBasell control of Brazil’s largest chemical maker




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Donald Ingber is leading efforts to develop organ-on-a-chip devices to replace animal tests

Widespread adoption of the chips will require mass production and finding the right questions to ask with the devices




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Out of the sea and into the factory for Acasti’s heart drug ingredient

Acasti picks CordenPharma to extract omega-3s from krill




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Sea, land, factory: 3 tales of pharmaceutical outsourcing

Drugs can be made by more than just chemical synthesis. Here are stories of three from the sea, the land, and yes, the factory




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Celgene partners with Skyhawk Therapeutics to drug RNA with small molecules

Skyhawk will receive $60 million up front to develop drug candidates that target RNA in neurological diseases




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Averiguan por qué a ciertos medicamentos les cuesta disminuir el tamaño de los tumores

Un estudio muestra cómo bloquear una enzima podría hacer más efectivos los tratamientos de un importante tipo de cánceres




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Ferreting out why some cancer drugs struggle to shrink tumors

Study shows how stopping one enzyme could help drugs treat an important class of cancers more effectively




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Decoding how insects use visual and chemical cues to find food

Chemical ecologist Shannon Olsson and neuroscientist Karin Nordström employ 3-D printing and virtual reality to answer pressing questions about pollinators




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Akero debuts with $65 million to tackle NASH




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How to foster a diverse workplace




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Boehringer Ingelheim to build a biologics research center




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EC investigates sale of Solvay’s nylon unit to BASF




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AkzoNobel, Thomas Swan to develop coatings for metal packaging




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Career Ladder: Chloe Poston

This chemist carved a path away from the bench to become an expert on the scientific workforce




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Honeywell and Chemours ask U.S. Supreme Court to hear appeal in HFC case




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Pot purveyors get wise to instrumentation; steelhead trout shift their genetic gears




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3-D printing start-up Carbon seeks to be found everywhere

The start-up is taking the technology deeper into manufacturing




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Thermo Fisher to buy electron microscopy supplies maker Gatan

Acquisition builds on recent purchases of electron microscope makers FEI and Phenom-World




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Meet <i>Science</i> magazine editor Jeremy Berg, chemist and proud data wonk

Policy leader talks about publishing, the scientific enterprise, and how chemistry fits into it all




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Canada moving to update environmental protection regulations

Actions may include requiring industry to demonstrate safety of substances, akin to Europe’s REACH program




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Canada moves to update environmental protection regulations




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Volunteer service award to Carolyn Ribes




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Organic photovoltaic window device generates electricity and blocks heat

Improvements to device may eventually cut external power demands for buildings by 50%




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Italmatch is sold by one private equity firm to another




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Silver nanowires make transparent fingerprint sensor prototype for smartphones

Sensor material outperforms conventional material by combining high transparency and low resistance




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Synthetic lava brings eruption into the lab

To learn more about lava’s unpredictable behavior and to mitigate its damage, scientists are creating and manipulating their own molten rock




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Ineos to build first European cracker in 20 years




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Calculations suggest flea and tick medications for pets could benefit people by controlling mosquitoes

These drugs could have beneficial population-wide effects in areas at risk for malaria and Zika, according to modeling study




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Single atoms catalyze Suzuki reactions

Flow chemistry process takes place on carbon nitride surface




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Mussels, potatoes, ‘Anne of Green Gables,’ and now microbial fermentation

How BioVectra became a world-scale pharmaceutical contractor on Prince Edward Island




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Thermo Fisher to buy electron microscopy supplies maker Gatan

Acquisition builds on recent purchases of electron microscope makers FEI and Phenom-World




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The unwritten rules of sharing in the laboratory

Chemjobber on when hoarding chemicals and lab equipment becomes a problem




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U.S. Supreme Court nominee Brett Kavanaugh likely to limit regulatory authority

Current district judge is viewed as reliably conservative, deferent to presidential power




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Genes found in the desert inspire drought-tolerant crop trial

PlantArcBio, an Israeli start-up, will try out its new soybean genes at the University of Wisconsin




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Trump’s tweets prompt Pfizer to postpone drug price hikes

The president deemed the price rollback a victory, but industry watchers say Pfizer could benefit in the long run




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Big data mining predicts toxicity better than animal tests




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Novartis to end anti-infectives R&D




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FTC takes Tronox and Cristal to federal court




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Brexit expected to spur emigration of scientists




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Zinc and manganese from batteries turned into nutrients




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South Korea’s SK to acquire Ampac Fine Chemicals




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Chemists fracture rings to install fluorine

Reaction opens unstrained nitrogen rings furnishing alkyl fluorine compounds