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A robust data analytical method to investigate sequence dependence in flow-based peptide synthesis

React. Chem. Eng., 2024, 9,825-832
DOI: 10.1039/D3RE00494E, Paper
Open Access
Bálint Tamás, Pietro Luigi Willi, Héloïse Bürgisser, Nina Hartrampf
A new data analytical method for flow-based peptide synthesis enables robust and quantitative analysis of sequence-dependent difficult couplings.
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A safe and new strategy for N-arylation of 2,4-thiazolidinediones via microwave irradiation using base catalyst K2CO3 in DMF

React. Chem. Eng., 2024, 9,842-848
DOI: 10.1039/D3RE00641G, Paper
Ragini C. Patil, Nita M. Khiratkar, Sumeer Ahmed, Joazaizulfazli Jamalis, Aso Hameed Hasan, Malika Berredjem, Sarkar M. A. Kawsar, Ajmal R. Bhat
Green efforts as an alternative to existing conventional methods for providing new tools, knowledge and design of organic synthesis, will contribute to the economy and protecting the environment and health.
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Machine-learning assisted optimisation during heterogeneous photocatalytic degradation utilising a static mixer under continuous flow

React. Chem. Eng., 2024, 9,872-882
DOI: 10.1039/D3RE00570D, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Thomas M. Kohl, Yan Zuo, Benjamin W. Muir, Christian H. Hornung, Anastasios Polyzos, Yutong Zhu, Xingdong Wang, David L. J. Alexander
Machine-learning assisted optimisation of a continuous photodegradation reaction, using a TiO2 coated catalytic static mixer successfully accounting for catalyst degradation.
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Continuous flow synthesis of the ionizable lipid ALC-0315

React. Chem. Eng., 2024, 9,959-966
DOI: 10.1039/D3RE00630A, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Jakob B. Wolf, Ju Weon Lee, Matthew B. Plutschack, Dario Cambié, Andreas Seidel-Morgenstern, Peter H. Seeberger
The ionizable lipid ALC-0315 is the major component of the lipid nanoparticles used to encapsulate the mRNA in the Biontech–Pfizer COVID-19 vaccine.
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Merging inline crystallization and pulsed flow operation to enable enantiospecific solid state photodecarbonylation

React. Chem. Eng., 2024, Advance Article
DOI: 10.1039/D4RE00058G, Paper
Open Access
Bavo Vandekerckhove, Bart Ruttens, Bert Metten, Christian V. Stevens, Thomas S. A. Heugebaert
Photoelimination of α-chiral ketones in the solid state results in highly regio- and enantiospecific C–C bond formation. By combining inline crystallisation and pulsatile flow, the photochemistry of these slurries can now be run fully continuously.
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Comprehensive Study of Lumped Kinetic Models and Bio-Oil Characterization in Microwave-Assisted Pyrolysis of Sargassum sp.

React. Chem. Eng., 2024, Accepted Manuscript
DOI: 10.1039/D3RE00674C, Paper
Teta Fathya Widawati, Muhammad Fuad Refki, Rochmadi Rochmadi, Arief Budiman
Indonesia, renowned for its tropical marine environments, boasts a rich diversity of macroalgae, with Sargassum being a major contributor. Currently, Sargassum's primary application revolves around alginate extraction, prompting a systematic...
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Thermokinetic analyses of metal-sensitive reactions in a ceramic flow calorimeter

React. Chem. Eng., 2024, Advance Article
DOI: 10.1039/D4RE00014E, Paper
Open Access
Soritz S., Sommitsch A., Irndorfer S., Brouczek D., Schwentenwein M., Priestley I. J. G., Iosub A. V., Krieger J. P., Gruber-Woelfler H.
A ceramic flow calorimeter for metal-sensitive reactions is characterized and used to obtain thermokinetic data on highly exothermic reactions.
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Photochemical organocatalytic heteroarylation of anilines and secondary alicyclic amines in continuous-flow

React. Chem. Eng., 2024, Advance Article
DOI: 10.1039/D4RE00130C, Paper
Egor N. Boronin, Milena M. Svetlakova, Ilya I. Vorobyov, Yulia B. Malysheva, Yuri V. Polushtaytsev, Sergey N. Mensov, Andrey V. Vorotyntsev, Alexey Yu. Fedorov, Timothy Noël, Alexander V. Nyuchev
Photoorganocatalytic arylation of amines in continuous-flow enables scaling up including decreasing of both reaction time and catalyst loading.
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On a seamlessly replicable circular photoreactor for lab-scale continuous flow applications

React. Chem. Eng., 2024, Accepted Manuscript
DOI: 10.1039/D4RE00109E, Paper
Yi-Hsuan Tsai, Martin Cattoen, Guillaume Masson, Gabrielle Christen, Lisa Traber, Morgan Donnard, Frederic R. Leroux, Guillaume Bentzinger, Sylvain Guizzetti, Jean-Christophe M. Monbaliu
A cost effective and replicable continuous flow circular photoreactor system is introduced. All body parts of the reactor are 3D-printed and the electronics are purchased from various mainstream suppliers. The...
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LatentView Analytics Q2FY25 net profit grows 17%

The acquisition of Decision Point Analytics has concluded and integration of the GTM and delivery teams is underway




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PFC turns down $2.4 billion debt to Shapoorji

With the latest move, the company may have to find new ways to raise money




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Industrial AI firm Avathon to focus on India for R&D growth, aims to triple workforce in two years

India will play a pivotal role in our expansion, serving as a hub for product engineering, delivery, support and R&D, says CEO Johan




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HCG records 33% consolidated PAT growth in Q2FY25

The company attributed this growth to increased volumes across modalities, which drove operational leverage




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Hindalco Q2 net up 78% on lower cost, better realisation

The revenue of Hindalco increased seven per cent to Rs ₹58,203 crore (Rs ₹54,169 crore)




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Grow your own grub

If the price of vegetables and concern about chemicals worries you, it’s time you turned an urban farmer and grew your own food. Your balcony, terrace, or your backyard can be your farm, says BHUMIKA K. August 25 is celebrated as World Kitchen Gardeners’ Day




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The glam girl among flowers

Gardening: Welcome the sturdy anthuriums and be assured of splashes of colour




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The time to sow

… is now, so start that garden today, says Hema Vijay




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Garden in a bowl

Anusha Babbar teaches people the art of creating terrariums, ideal for a world starved of green




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How does my garden grow?

From every corner and crevice of Elsy Joseph’s little home blooms a flower or a vegetable




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Bamboo power

Bamboo produces 35 per cent more oxygen than other trees, is an effective carbon sink, and its biomass is a cheap and efficient fuel for power generation units.




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How to choose the right vine

Vines are among the most versatile of landscaping elements, lending themselves to a wide range of uses, says garden expert Vrinda Kumble




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How does your garden grow?

Or rather where would be a better question as Bangaloreans increasingly explore balcony gardens




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How much is too much?

When can water become too much of a good thing? Enthusiastic gardeners often make the mistake of over-watering their plants




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Country of flowers

Britain is blooming mad. And it shows. The writer visited London this summer and describes its garden policy




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Home-grown solutions to life’s little problems

Subashree has proved a home garden is all it takes to have good health, good looks and a good life




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Say it with flowers

How do you give your rooms a feminine touch without being too girly?




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‘Planned’ growth for trees

Existing trees should be pruned at frequent intervals to have the required crown shape and to enhance the aesthetics of the roadscape




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Gingery flowers

Ginger lilies offer everything you would want in a flower — a great presence, fragrance, and they can last real long in a vase.




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City is now under denser tree cover

Bengaluru’s arboreal history records that trees were initially planted for spiritual reasons. They have followed the ornamental, archival and commercial trajectory since then




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Along the gut-bone marrow signaling pathway: use of longan polysaccharides to regenerate blood cells after chemotherapy-induced myelosuppression

Food Funct., 2024, Advance Article
DOI: 10.1039/D4FO03758H, Paper
Shiai Zeng, Lan Gao, Kai Wang, Xuwei Liu, Zhuoyan Hu, Lei Zhao
TLPL promoted the production of Lactobacillus in myelosuppressed mice, and promoted the haematopoiesis of bone marrow cells via the gut-bone marrow axis.
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Pentadecanoic acid (C15:0, PA) induces mild maternal glucose intolerance and promotes the growth of the offspring partly through up-regulating liver PPARα and MAPK signaling pathways

Food Funct., 2024, Advance Article
DOI: 10.1039/D4FO03970J, Paper
Jun Wang, Shiqi Zheng, Ziying Li, Yimei Tang, Yanhua Huang, Junwen Wang, Rui Li, Jie Peng
1% PA can induce a mild decrease in the maternal glucose tolerance and lipolysis mainly by activated MAPK and PPARα signaling.
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Specific vegetable types are associated with lower long-term risk for late-life dementia: the Perth Longitudinal Study of Aging Women

Food Funct., 2024, 15,10885-10895
DOI: 10.1039/D4FO03239J, Paper
Negar Ghasemifard, Simone Radavelli-Bagatini, Simon M. Laws, Helen Macpherson, Emma Stevenson, Jonathan M. Hodgson, Richard L. Prince, Joshua R. Lewis, Marc Sim
This study found an association between total vegetable intake as well as specific types of vegetables including yellow/orange/red, green leafy, and allium vegetables with lower long-term risk for late-life dementia in older women.
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Inhibitory effect of tea flower polysaccharides on oxidative stress and microglial oxidative damage in aging mice by regulating gut microbiota

Food Funct., 2024, Advance Article
DOI: 10.1039/D4FO03484H, Paper
Yidan Cai, Siyu Liu, Xing Ge, Lu Cheng, Xin Zhang
Tea flower polysaccharides (TFPS) can improve the disorder of gut microbiota, alleviate oxidative damage to glial cells, alleviate neuroinflammation, and play a role in delaying aging.
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Summer–autumn tea promotes adipocyte browning and thermogenesis in association with gut microbiota regulation in high-fat diet-fed mice

Food Funct., 2024, Advance Article
DOI: 10.1039/D4FO03826F, Paper
Chengcheng Yang, Luyao Liu, Yao Du, Lu Zhao, Lu Liu, Xingbin Yang, Yan Zhao
This study revealed for the first time the anti-obesity effect of summer–autumn tea aqueous extract (SATE) and its underlying mechanism.
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Allergenicity evaluation of an extensively hydrolyzed infant formula based on cow milk protein

Food Funct., 2024, 15,11036-11046
DOI: 10.1039/D4FO03582H, Paper
Hongbo Li, Lin Yang, Jiayi Li, Quan Gao, Tiantian Liu, Yang Zou, Xiaohong Chen, Hongjuan Li, Jinghua Yu
We developed an extensively hydrolyzed infant formula (EHF) with a protein composition similar to breast milk (whey protein-to-casein ratio of 6 : 4) and evaluated its sensitization in vitro and in vivo.
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Development of Pickering water-in-oil emulsions using a dual stabilization of candelilla wax and acylated EGCG derivatives to enhance the survival of probiotics (Lactobacillus plantarum) powder

Food Funct., 2024, 15,11141-11157
DOI: 10.1039/D4FO01342E, Paper
Zhaojuan Shi, Jun Wu, Xingting Wang, Tongqiao Nie, Qingmei Zeng, Chuanxun Yuan, Risheng Jin
Candelilla wax reinforced the stability of Pickering W/O emulsions with a three-dimensional crystal network. The oil phase volume fraction of the emulsions showed dramatic differences in protecting probiotic viability from environmental stresses.
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Correction: Using integrated transcriptomics and metabolomics to explore the effects of infant formula on the growth and development of small intestinal organoids

Food Funct., 2024, Advance Article
DOI: 10.1039/D4FO90094D, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Xianli Wang, Yuxin Jing, Chengdong Zheng, Chenxuan Huang, Haiyang Yao, Zimo Guo, Yilun Wu, Zening Wang, Zhengyang Wu, Ruihong Ge, Wei Cheng, Yuanyuan Yan, Shilong Jiang, Jianguo Sun, Jingquan Li, Qinggang Xie, Xiaoguang Li, Hui Wang
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New Zealand makes history, and how

Notching up a Test series win in India for the first time, the Kiwis were dominant, thanks largely to the contributions of Rachin Ravindra and Mitchell Santner




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Below the Line




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Editorial. India needs to focus on being a global AI power

The country’s vast pool of skilled professionals in engineering, data science and software development puts it in a position to become a global AI hub




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The angst over China’s slowdown

Though China’s growth has slowed in recent years, its dire consequences and impact on world economy are exaggerated




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How costly is it to produce money?

Cost-benefit analyses key to determining the features and designs that go into making various notes




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Which States are leading the race towards renewables in India?

India with 300 days of sunshine each year, possesses vast solar energy potential. The National Institute of Energy estimated the country’s solar potential at 748 GW, assuming solar PV modules cover 3% of the geographical surface. Solar energy is expected to be the main driver pushing India closer to its renewable energy targets. Diving deep into the state-wise push towards solar energy. Rajasthan, Gujarat, Tamil Nadu and Karnataka are the leading States in India, both in terms of installed capacities and power generation, in the solar segment. Also, with respect to solar energy projects, Rajasthan and Gujarat lead in terms of the capacities added since FY22 and projects in pipeline




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Tepid FDI flows call for a policy review

The government must look beyond rules and procedures and rationalise taxation, particularly in sectors like electronics




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Below the line




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Understanding the election process: How is the US President elected?

While citizens cast their votes, the actual selection of the president is determined by the Electoral College




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How discoms have spurred renewables

Long term power purchase agreements have de-risked investments by private developers in renewables. But discoms need to invest in storage now




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Empower seniors digitally

It’s vital for wellness, full participation in society




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Growth matters more than inflation now

The global post-Covid fight against inflation is over, while India’s growth has slipped. It’s time for the RBI to take stock




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Editorial. Growing rice acreage points to need for PDS reform

A household of five individuals does not need 25 kg of free grain per month. Instead, with the same level of food subsidy, pulses and oils can be introduced, where they don’t find a place in the PDS already