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Bilberry anthocyanin extracts enhance anti-PD-L1 efficiency by modulating gut microbiota

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Food Funct., 2020, 11,3180-3190
DOI: 10.1039/D0FO00255K, Paper
Luoyang Wang, Guoqiang Jiang, Nan Jing, Xuerun Liu, Qicheng Li, Wei Liang, Zheng Liu
Bilberry anthocyanin extracts change the gut microbiota and enhance the anti-tumor efficiency of the PD-L1 antibody.
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Capsaicin—the major bioactive ingredient of chili peppers: bio-efficacy and delivery systems

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Food Funct., 2020, 11,2848-2860
DOI: 10.1039/D0FO00351D, Review Article
Muwen Lu, Chengyu Chen, Yaqi Lan, Jie Xiao, Run Li, Junqing Huang, Qingrong Huang, Yong Cao, Chi-Tang Ho
The mechanisms of bio-efficacy of capsaicin and delivery systems with enhanced bioavailability were reviewed.
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Untargeted metabolomics revealed therapeutic mechanisms of icariin on low bone mineral density in older caged laying hens

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Food Funct., 2020, 11,3201-3212
DOI: 10.1039/C9FO02882J, Paper
Jie Huang, Yanping Hu, Xiaofeng Tong, Lei Zhang, Zhengwang Yu, Zhongxin Zhou
Untargeted metabolomics revealed the therapeutic effects and mechanisms of icariin on low bone mineral density in older caged laying hens.
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Tilapia head glycolipids reduce inflammation by regulating the gut microbiota in dextran sulphate sodium-induced colitis mice

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Food Funct., 2020, 11,3245-3255
DOI: 10.1039/D0FO00116C, Paper
Zhipeng Gu, Yujie Zhu, Shuaiming Jiang, Guanghua Xia, Chuan Li, Xueying Zhang, Jiachao Zhang, Xuanri Shen
Tilapia head glycolipids reduce inflammation by regulating the gut microbiota in dextran sulphate sodium-induced colitis mice.
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Girinimbine from curry leaves promotes gastro protection against ethanol induced peptic ulcers and improves healing via regulation of anti-inflammatory and antioxidant mechanisms

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Food Funct., 2020, 11,3493-3505
DOI: 10.1039/D0FO00053A, Paper
Syam Mohan, Yahya Hasan Hobani, Emad Shaheen, Alaa Sayed Abou-Elhamd, Aymen abdelhaleem, Hassan A. Alhazmi, Siddig Ibrahim Abdelwahab
Curry leaves (Murraya koenigii) are a leafy spice used in Indian cookery for its fragrant aroma.
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Purification, characterization and molecular cloning of a dicaffeoylquinic acid-hydrolyzing esterase from human-derived Lactobacillus fermentum LF-12

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Food Funct., 2020, 11,3235-3244
DOI: 10.1039/D0FO00029A, Paper
Yujin Liu, Minhao Xie, Peng Wan, Guijie Chen, Chunxu Chen, Dan Chen, Shijie Yu, Xiaoxiong Zeng, Yi Sun
Dicaffeoylquinic acids (DiCQAs), the main components of kudingcha made from the leaves of Ilex kudingcha, could be transformed by gut microbiota.
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Inducing secondary structural interplays between scallop muscle proteins and soy proteins to form soluble composites

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Food Funct., 2020, 11,3351-3360
DOI: 10.1039/C9FO03106E, Paper
Chao Wu, Jiamei Wang, Xiaokang Na, Zhenyu Wang, Xianbing Xu, Tao Wang
Scallop muscle proteins and soya proteins were packed into a composite with tunable internal, molecular arrangements of the secondary structures.
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Quantifying dietary vitamin K and its link to cardiovascular health: a narrative review

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Food Funct., 2020, 11,2826-2837
DOI: 10.1039/C9FO02321F, Review Article
Claire R. Palmer, Lauren C. Blekkenhorst, Joshua R. Lewis, Natalie C. Ward, Carl J. Schultz, Jonathan M. Hodgson, Kevin D. Croft, Marc Sim
Potential beneficial pathways by which vitamin K may reduce the risk of cardiovascular disease mortality.
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Protocatechuic acid and quercetin glucosides in onions attenuate changes induced by high fat diet in rats

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Food Funct., 2020, 11,3585-3597
DOI: 10.1039/C9FO02633A, Paper
Katarzyna Grzelak-Błaszczyk, Joanna Milala, Krzysztof Kołodziejczyk, Michał Sójka, Andrzej Czarnecki, Monika Kosmala, Robert Klewicki, Bartosz Fotschki, Adam Jurgoński, Jerzy Juśkiewicz
Yellow onion waste from industrial peeling was used to obtain three pure preparations: protocatechuic acid (PA), quercetin diglycosides (QD) and quercetin monoglycosides (QM).
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Integrated anti-hyperlipidemic bioactivity of whole Citrus grandis [L.] osbeck fruits—multi-action mechanism evidenced using animal and cell models

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Food Funct., 2020, 11,2978-2996
DOI: 10.1039/C9FO02290B, Paper
Li-Yun Lin, Boa-Chan Huang, Kuan-Chou Chen, Robert Y. Peng
Multi- antihyperlipidemic mechanism revealed by the pomelo phytonutrients. Both the sterol synthesis and lipogenesis pathways are affected by the pomelo phytonutrients. Dotted line: from citation. Solid line: verified in this experiment.
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Proteomic landscape of liver tissue in old male mice that are long-term treated with polysaccharides from Sargassum fusiforme

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Food Funct., 2020, 11,3632-3644
DOI: 10.1039/D0FO00187B, Paper
Peichao Chen, Ya Zhang, Man Xu, Hongjun Chen, Huixi Zou, Xu Zhang, Haibin Tong, Cuiping You, Mingjiang Wu
The polysaccharides extracted from Sargassum fusiforme delays the aging process via mitochondria-associated anti-oxidation.
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Chronic flavanol-rich cocoa powder supplementation reduces body fat mass in endurance athletes by modifying the follistatin/myostatin ratio and leptin levels

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Food Funct., 2020, 11,3441-3450
DOI: 10.1039/D0FO00246A, Paper
Jose Ángel García-Merino, Diego Moreno-Pérez, Beatriz de Lucas, Maria Gregoria Montalvo-Lominchar, Elsa Muñoz, Lara Sánchez, Fernando Naclerio, Karen Marlene Herrera-Rocha, Martha Rocío Moreno-Jiménez, Nuria Elisabeth Rocha-Guzmán, Mar Larrosa
Flavanols-rich cocoa reduced body fat composition in athletes through modulation of follistatin and leptin levels.
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Addition of flavonols and polysaccharides as excipient ingredients into epicatechin rich green tea extract inhibited free radical formation and glucose uptake

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Food Funct., 2020, 11,3105-3111
DOI: 10.1039/C9FO03020D, Paper
So-Hee Yoo, Yeong-Eun Lee, Jin-Oh Chung, Chan-Su Rha, Yong-Deog Hong, Mi-Young Park, Soon-Mi Shim
Results from the current study suggested that whole green tea components rich in flavonols and polysaccharides could be potential hypoglycemic excipient ingredients into green tea catechins by enhancing catechin absorption.
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cis 9, trans 11, but not trans 10, cis 12 CLA isomer, impairs intestinal epithelial barrier function in IPEC-J2 cells and mice through activation of GPR120-[Ca2+]i and the MLCK signaling pathway

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Food Funct., 2020, 11,3657-3667
DOI: 10.1039/D0FO00376J, Paper
Han Su, Weijie Zhao, Fenglin Zhang, Min Song, Fangfang Liu, Jisong Zheng, Mingfa Ling, Xiaohua Yang, Qiang Yang, Haiwen He, Lin Chen, Xumin Lai, Xiaotong Zhu, Lina Wang, Ping Gao, Gang Shu, Qingyan Jiang, Songbo Wang
In vitro and in vivo studies show that c9, t11-CLA, but not t10, c12-CLA isomer, impairs intestinal epithelial barrier function in IPEC-J2 cells and mice via activation of GPR120-[Ca2+]i and the MLCK pathway.
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Cloning, expression and comparison of the properties of Scy p 9, a Scylla paramamosain allergen

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Food Funct., 2020, 11,3006-3019
DOI: 10.1039/D0FO00004C, Paper
Xin-Rong He, Yi-Meng Cheng, Yang Yang, Jie-Jing Xie, Ka-Hou Chu, Yong-Xia Zhang, Gui-Xia Chen, Hong Liu, Min-Jie Cao, Guang-Ming Liu
This study investigated the properties of Scy p 9 in mud crab (Scylla paramamosain).
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Molecular mechanisms of selenium-biofortified soybean protein and polyphenol conjugates in protecting mouse skin damaged by UV-B

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Food Funct., 2020, 11,3563-3573
DOI: 10.1039/C9FO02560J, Paper
Xing Zhang, Hui He, Tao Hou
A new selenium-biofortified protein and polyphenol conjugate with high antioxidant activity and stability for the treatment of photooxidation-related diseases.
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Correction: 5-Heptadecylresorcinol attenuates oxidative damage and mitochondria-mediated apoptosis through activation of the SIRT3/FOXO3a signaling pathway in neurocytes

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Food Funct., 2020, 11,3749-3749
DOI: 10.1039/D0FO90012E, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Jie Liu, Yu Wang, Yiming Hao, Zongwei Wang, Zihui Yang, Ziyuan Wang, Jing Wang
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Lycium barbarum polysaccharides ameliorate intestinal barrier dysfunction and inflammation through the MLCK-MLC signaling pathway in Caco-2 cells

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Food Funct., 2020, 11,3741-3748
DOI: 10.1039/D0FO00030B, Paper
Wei Li, Mingbo Gao, Ting Han
Impairment of the intestinal barrier often occurs in inflammatory bowel diseases, and pro-inflammatory factors play a vital role in the pathogenesis of intestinal diseases.
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Correction: Matrix-mediated distribution of 4-hydroxy-2-hexanal (nonenal) during deep-frying of chicken breast and potato sticks in vegetable oil

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Food Funct., 2020, 11,3750-3750
DOI: 10.1039/D0FO90018D, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Lukai Ma, Guoqin Liu, Weiwei Cheng, Xinqi Liu, Huifan Liu, Qin Wang
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Dietary intakes of flavonoids and carotenoids and the risk of developing an unhealthy metabolic phenotype

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Food Funct., 2020, 11,3451-3458
DOI: 10.1039/C9FO02852H, Paper
Nazanin Moslehi, Mahdieh Golzarand, Farhad Hosseinpanah, Parvin Mirmiran, Fereidoun Azizi
This study was designed to investigate prospective associations between dietary habitual intakes of flavonoids and carotenoids and the development of an unhealthy metabolic phenotype separately in normal-weight and excess weight individuals.
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Hot-water extract of ripened Pu-erh tea attenuates DSS-induced colitis through modulation of the NF-κB and HIF-1α signaling pathways in mice

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Food Funct., 2020, 11,3459-3470
DOI: 10.1039/C9FO02803J, Paper
Yina Huang, Liang Qiu, Xuan Mi, Zhihong Zhang, Di Xu, Xueying Tao, Keyu Xing, Qinglong Wu, Hua Wei
There was lots of information on anti-obesity and reduced risk of cardiovascular disease, to our best knowledge, little was known about the prevention of colitis by RPT. We firstly assessed effects of RPT on phenotypic improvements of DSS-induced colitis in mice.
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Potential neurotoxicity of 5-hydroxymethylfurfural and its oligomers: widespread substances in carbohydrate-containing foods

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Food Funct., 2020, Advance Article
DOI: 10.1039/C9FO02526J, Paper
Cheng Wang, Zhenru Liu, Tian Hu, Youjia Li, Rui Liu, Junjie Zhang, Huaizhen He
5-Hydroxymethylfurfural (5-HMF) and its acid-catalyzed oligomers can inhibit nerve cell proliferation and induce neurological deficits at near or below the reported 24 h dietary intake of 5-HMF in humans.
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Alleviating effects of noni fruit polysaccharide on hepatic oxidative stress and inflammation in rats under a high-fat diet and its possible mechanisms

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Food Funct., 2020, 11,2953-2968
DOI: 10.1039/D0FO00178C, Paper
Xiaobing Yang, Wenjing Mo, Chuanjin Zheng, Wenzhi Li, Jian Tang, Xiaoyong Wu
Non-alcoholic fatty liver disease is associated with gut microbiota, oxidative stress, and inflammation.
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Flavonoids isolated from loquat (Eriobotrya japonica) leaves inhibit oxidative stress and inflammation induced by cigarette smoke in COPD mice: the role of TRPV1 signaling pathways

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Food Funct., 2020, 11,3516-3526
DOI: 10.1039/C9FO02921D, Paper
Tunyu Jian, Jian Chen, Xiaoqin Ding, Han Lv, Jiawei Li, Yuexian Wu, Bingru Ren, Bei Tong, Yuanyuan Zuo, Kelei Su, Weilin Li
Total flavonoids isolated from loquat leaves inhibit inflammation and oxidative stress by regulating TRPV1 and the related pathway in cigarette smoke-induced COPD mice.
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A rapid protocol to distinguish between Citri Exocarpium Rubrum and Citri Reticulatae Pericarpium based on the characteristic fingerprint and UHPLC-Q-TOF MS methods

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Food Funct., 2020, 11,3719-3729
DOI: 10.1039/D0FO00082E, Paper
Liqiang Shi, Rongjin Wang, Tianshu Liu, Jiajie Wu, Hongxu Zhang, Zhiqiang Liu, Shu Liu, Zhongying Liu
Citri Exocarpium Rubrum and Citri Reticulatae Pericarpium were successfully distinguished by the characteristic fingerprint and UHPLC-Q-TOF MS methods.
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A lupine (Lupinus angustifolious L.) peptide prevents non-alcoholic fatty liver disease in high-fat-diet-induced obese mice

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Food Funct., 2020, 11,2943-2952
DOI: 10.1039/D0FO00206B, Paper
Open Access
Ana Lemus-Conejo, Elena Grao-Cruces, Rocio Toscano, Lourdes M. Varela, Carmen Claro, Justo Pedroche, Francisco Millan, Maria C. Millan-Linares, Sergio Montserrat-de la Paz
A lupine (Lupinus angustifolious L.) peptide prevents non-alcoholic fatty liver disease in high-fat-diet-induced obese mice.
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Kaempferol modulates TCDD- and t-BHQ-induced drug-metabolizing enzymes and luteolin enhances this effect

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Food Funct., 2020, 11,3668-3680
DOI: 10.1039/C9FO02951F, Paper
Tomoya Kitakaze, Atsushi Makiyama, Rika Nakai, Yuki Kimura, Hitoshi Ashida
Co-treatment with kaempferol and luteolin inhibits AhR- and Nrf2-induced expression of drug-metabolizing enzymes.
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tert-Butyl-p-benzoquinone induces autophagy by inhibiting the Akt/mTOR signaling pathway in RAW 264.7 cells

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Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00281J, Paper
Xianghe Meng, Chaosheng Xia, Qin Ye, Xiaohua Nie
Autophagy mediate by p53/Akt/mTOR signaling was linked to overproduction of ROS by tert-butyl-p-benzoquinone.
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Comparison of the effects of resveratrol and its derivative pterostilbene on hepatic oxidative stress and mitochondrial dysfunction in piglets challenged with diquat

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Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00732C, Paper
Hao Zhang, Yanan Chen, Yueping Chen, Peilu Jia, Shuli Ji, Jianxiong Xu, Yue Li, Tian Wang
Pterostilbene is more effective than resveratrol in alleviating liver injury, facilitating redox status, and improving mitochondrial function of piglets.
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Bergaptol from blossoms of Citrus aurantium L. var. amara Engl inhibits LPS-induced inflammatory responses and ox-LDL-induced lipid deposition

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Food Funct., 2020, Accepted Manuscript
DOI: 10.1039/C9FO00255C, Paper
Chun-Yan Shen, Tian-Xing Wang, Jian-Guo Jiang, Chun-Ling Huang, Wei Zhu
Aberrant activation of inflammation and excess accumulation of lipids play pivotal roles in atherosclerosis (AS) progression. Constituents from Citrus aurantium Linn variant amara Engl (CAVA) were effectively investigated for their...
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Targets and Underlying Mechanisms for Sedative and Hypnotic Activities of Saponins from Semen Ziziphus jujube

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Food Funct., 2020, Accepted Manuscript
DOI: 10.1039/D0FO00098A, Paper
Chun-Yan Shen, Lin Wan, Jing-Jing Zhu, Jian-Guo Jiang
Semen Ziziphus jujube (SZJ) has been widely consumed as edible resources in China to treat insomnia disorders. However, the underlying mechanisms and potential therapeutic targets remained obscure. SZJ-I and SZJ-II...
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Red ginseng protects against cisplatin-induced intestinal toxicity by inhibiting apoptosis and autophagy via the PI3K/AKT and MAPK signaling pathways

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Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00469C, Paper
Jun-jie Zhang, Jian-qiang Wang, Xing-yue Xu, Jia-yu Yang, Zi Wang, Shuang Jiang, Ying-ping Wang, Jing Zhang, Rui Zhang, Wei Li
Although growing evidence has shown that ginseng (Panax ginseng C.A. Meyer.) exerts strong protective and preventive effects on cisplatin-induced side effects, the ameliorative effects of ginseng on intestinal damage caused by cisplatin are unknown to date.
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Superior hypoglycemic activity of mulberry lacking monosaccharides is accompanied by better activation of the PI3K/Akt and AMPK signaling pathways

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Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00427H, Paper
Xiao-Shan Long, Sen-Tai Liao, Peng Wen, Yu-Xiao Zou, Fan Liu, Wei-Zhi Shen, Teng-Gen Hu
Mulberry removed monosaccharides (FM) displayed better hypoglycemic activity than untreated mulberry (MP), which may be attributed the stronger effects of FM on activating PI3K/Akt and AMPK signaling pathways.
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Production of GABA-enriched idli with ACE inhibitory and antioxidant properties using Aspergillus oryzae: the antihypertensive effects in spontaneously hypertensive rats

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Food Funct., 2020, Advance Article
DOI: 10.1039/C9FO02854D, Paper
Mohsen Zareian, Ehsan Oskoueian, Marjan Majdinasab, Bita Forghani
The present study aimed to develop a fermented food (idli) with enhanced γ-aminobutyric acid (GABA) and angiotensin I-converting enzyme (ACE) inhibitory properties using a GABA-producing fungus.
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Structural and physicochemical changes in almond milk during in vitro gastric digestion: impact on the delivery of protein and lipids

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Food Funct., 2020, Advance Article
DOI: 10.1039/C9FO02465D, Paper
Xin Wang, Aiqian Ye, Harjinder Singh
The gastric digestion of almond milk in a human gastric simulator resulted in major structural and physicochemical changes. The changes had significant impact on the rate of delivery of protein and lipids to the small intestine.
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Lactic acid bacteria alleviates polycystic ovarian syndrome by regulating sex hormone related gut microbiota

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Food Funct., 2020, Accepted Manuscript
DOI: 10.1039/C9FO02554E, Paper
Yufeng He, Qianqian Wang, Xiu Li, Gang Wang, Jianxin Zhao, Hao Zhang, Wei Chen
Polycystic ovarian syndrome (PCOS) is a common endocrine disease across the world. Because gut microbiota play a key role in the pathogenesis of PCOS, probiotics may alleviate PCOS symptoms through...
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The cognitive effects of an acute wild blueberry intervention on 7 – 10 year olds using extended memory and executive function task batteries.

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Food Funct., 2020, Accepted Manuscript
DOI: 10.1039/C9FO02284H, Paper
Adrian Robert Whyte, Daniel J Lamport, Graham Schafer, Claire M. Williams
Evidence for the health benefits of blueberries is well documented. In particular memory and executive function benefits have both been found for children aged 7 – 10 in the 6...
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Sugar matters: sugar moieties as reactivity-tuning factors in quercetin O-glycosides

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Food Funct., 2020, Accepted Manuscript
DOI: 10.1039/D0FO00319K, Paper
Cezara Zagrean-Tuza, Augustin C Moţ, Tomasz Chmiel, Attila Bende, Ioan Turcu
Quercetin, one of the most abundant flavonoids in plant-based foods, commonly occurs in nature in various glycosylated forms. There is still a less explored aspect regarding the cause of its...
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Unveiling the bioactivity potential of Allium triquetrum L. lipophilic fraction: chemical characterization and in vitro antibacterial activity against methicillin-resistant Staphylococcus aureus

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Food Funct., 2020, Accepted Manuscript
DOI: 10.1039/D0FO00769B, Paper
Samia Rabah, Kahina Kouachi, Patricia Ramos, Ana T. P. C. Gomes, Adelaide Almeida, Hayate Haddadi-Guemghar, Khodir Madani, Armando Silvestre, Sónia A. O. Santos
The lipophilic composition of Allium triquetrum L. bulbs, flowers and leaves was studied for the first time, by GC-MS. Sixty-two compounds were firstly identified in A. triquetrum L. Fatty acids...
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Evaluation of Tenebrio molitor protein as a source of peptides for modulating physiological processes

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Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00734J, Paper
Fernando Rivero Pino, Raúl Pérez Gálvez, F. Javier Espejo Carpio, Emilia M. Guadix
Tenebrio molitor hydrolysates produced with commercial proteases showed improved ACE inhibitory and antioxidant properties. This source could be employed as functional ingredient in food preparations.
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Pedro Ximenez sun-dried grape must: a dietary supplement for a healthy longevity

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Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00204F, Paper
Noelia Morales-Prieto, Paula V. Huertas-Abril, Nieves López de Lerma, Isabel. L. Pacheco, José Pérez, Rafael Peinado, Nieves Abril
Sun-dried Pedro Ximénez white grapes must (PXM) is a potent antioxidant that regularizes apoptosis, proliferation, and regeneration of the structure and the function of aged mice liver. PXM consumption contributes to a healthy aging process.
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Dietary supplementation of L-arginine and N-carbamylglutamate enhances duodenal barrier and mitochondrial functions and suppresses duodenal inflammation and mitophagy in suckling lambs suffering from intrauterine-growth-restriction

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Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00019A, Paper
Hao Zhang, Yi Ma, Mengzhi Wang, Mabrouk Elsabagh, Juan J. Loor, Hongrong Wang
The work aimed at investigating the effects of N-carbamylglutamate (NCG) or L-arginine (Arg) supplementation on the duodenal mitophagy, inflammation, and barrier function in suckling lambs suffering from intrauterine-growth-retardation (IUGR).
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The role of extensional rheology in the oral phase of swallowing: an in vitro study

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Food Funct., 2020, Advance Article
DOI: 10.1039/C9FO02327E, Paper
Marco Marconati, Marco Ramaioli
In vitro swallowing experiments suggest that thin, viscoelastic liquids with strong apparent extensional viscosity lead to fast transit, lower oral residues and a compact bolus leaving the oral cavity.
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Supplementation of Bacillus amyloliquefaciens AS385 culture broth powder containing 1-deoxynojirimycin in a high-fat diet altered the gene expressions related to lipid metabolism and insulin signaling in mice epididymal white adipose tissue

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Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00271B, Paper
Isabella Supardi Parida, Soo Takasu, Junya Ito, Ryoichi Ikeda, Kenji Yamagishi, Toshiyuki Kimura, Takahiro Eitsuka, Kiyotaka Nakagawa
Supplementation of Bacillus amyloliquefaciens AS385 culture broth powder in high-fat diet restored adiposity, glucose tolerance and insulin sensitivity in mice.
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Deciphering calcium-binding behaviors of casein phosphopeptides by experimental approaches and molecular simulation

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Food Funct., 2020, Accepted Manuscript
DOI: 10.1039/D0FO00844C, Paper
Minna Luo, Jie Xiao, Shengwei Sun, Fengchao Cui, Wei Li, Guo Liu, Yunqi Li, Yong Cao
Although specific groups in casein phosphopeptides (CPPs) have been identified to be essential for the calcium-binding capacity, how calcium binds with CPPs remains unclear. In the present study, experimental methods...
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Pterostilbene prevents LPS-induced early pulmonary fibrosis by suppressing oxidative stress, inflammation and apoptosis in vivo

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Food Funct., 2020, Advance Article
DOI: 10.1039/C9FO02521A, Paper
Huahong Yang, Cong Hua, Xiaolin Yang, Xiaoye Fan, Hongyu Song, Liping Peng, Xinxin Ci
Schematic model of the protective effects by Pts on LPS-induced lung fibrosis.
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Polysaccharides from Enteromorpha prolifera protect against carbon tetrachloride-induced acute liver injury in mice via activation of Nrf2/HO-1 signaling, and suppression of oxidative stress, inflammation and apoptosis

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Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00575D, Paper
Fuchuan Guo, Xinyun Zhuang, Mengyuan Han, Wenting Lin
EPP protected against hepatic injury induced by CCl4-derived reactive intermediates through the suppression of hepatic oxidative stress, inflammation, and apoptosis.
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Unsaturated alginate oligosaccharides attenuated obesity-related metabolic abnormalities by modulating gut microbiota in high-fat-diet mice

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Food Funct., 2020, Accepted Manuscript
DOI: 10.1039/C9FO02857A, Paper
Shangyong Li, Linna Wang, Bo Liu, Ningning He
Gut microbiota plays an important role in the high-fat diet (HFD)-induced obesity and related metabolic syndrome (MetS). Our previous study has demonstrated that unsaturated alginate oligosaccharides (UAOS) degraded by alginate...
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Protective effects of Bifidobacterium adolescentis on collagen-induced arthritis in rats depend on timing of administration

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Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00077A, Paper
Zhexin Fan, Bo Yang, R. Paul Ross, Catherine Stanton, Guoxun Shi, Jianxin Zhao, Hao Zhang, Wei Chen
Early probiotics adminitration is a key timing to alleviate inflammation in rats with arthritis.
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Adjunctive vitamin A and D during pulmonary tuberculosis treatment: a randomized controlled trial with a 2×2 factorial design

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Food Funct., 2020, Accepted Manuscript
DOI: 10.1039/C9FO02751C, Paper
Jinyu Wang, Ke Xiong, Qiuzhen Wang, Shanliang Zhao, Yufeng Liu, Aiguo Ma
Background and objective: Vitamin A and D have immunoregulatory effects and may improve the response to pulmonary tuberculosis treatment. The interaction of vitamin A and D on pulmonary tuberculosis treatment...
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