ng

[ASAP] Effect of Temperature on <sup>1</sup>H NMR Spectra, Antitrypanosomal Activity, Conformational Analysis, and Molecular Docking of Curine Derivatives from <italic toggle="yes">Berberis brevissima</italic>

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.9b00397




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[ASAP] A Grand Challenge. 3. Unbiased Phenotypic Function of Metabolites from Australia Plants <italic toggle="yes">Gloriosa superba</italic> and <italic toggle="yes">Alangium villosum</italic> against Parkinson

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.9b00880




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How tiny dependencies can topple the JavaScript Jenga tower

#486 — May 1, 2020

Unsubscribe  :  Read on the Web

JavaScript Weekly

???? I18n Ally: An All-in-One i18n Extension for VS Code — Got some internationalization work to do? I18n Ally gives you inline annotations, automated translations via Google Translate (which you can review), progress indication, etc. Supports React, Angular, Vue and other frameworks.

Anthony Fu

How a Few Lines of Code Broke Lots of Packages — Just under a week ago, people were reporting that create-react-app was broken. The culprit? A tiny change in a tiny dependency: is-promise. Luckily a fix was out very quickly and the creator of is-promise reflects on what happened here. Liran Tal also has some analysis of the situation.

Forbes Lindesay

Identify Front-End Issues Like JavaScript or Network Errors Fast — Datadog’s algorithmic alerts will proactively alert on any client-side issues such as JavaScript and network errors. Optimize the load time of your front-end resources, and detect any UI issues that affect critical user journeys. Try it free with Datadog Synthetics.

Datadog sponsor

Q: A JavaScript 'Quantum Circuit' Simulator — Bring quantum computing to your browser with this JavaScript simulation. If you were never quite sure what your JavaScript code was going to do, now you can formally explore the concept ????

Stewart Smith

Quick bytes:

???? Jobs

Find a Job Through Vettery — Vettery specializes in tech roles and is completely free for job seekers. Create a profile to get started.

Vettery

Senior Full-Stack Developer (Malmö/Sweden) — Every day is different from the next. Join our upbeat Team and work on exciting, major projects using a modern JavaScript stack.

Ortelius AB

???? Tutorials

A Guide to window.location — A breakdown that covers most of the methods and properties available on the DOM’s window.location object.

samantha ming

Implementing Dark Mode in React Apps Using styled-components

Blessing Krofegha

▶  Let's Build a Financial Dashboard App with React (Webinar On‑Demand) — Join TJ VanToll as he walks you through building a responsive Bootstrap-themed Stocks Portfolio app. Check it out today.

Progress KendoReact sponsor

Getting Started with NuxtJS — Learn how to create Vue.js-powered server-side rendered apps with NuxtJS including configuring an app and deploying it on Heroku.

Timi Omoyeni

▶  Learn Svelte: A 16-Part Course on Learning the Popular UI Framework — The course centers around building a chatbot, which is a nice change from the todos and other overused tutorial examples.

noah kaufman

10 Practical JavaScript Tricks — These kinds of lists are usually pretty run of the mill, but this one actually contains some lesser-known quick tips that you may not have seen before.

zander shirley

Moving TinyMCE to Modern JavaScript — The creators of TinyMCE (a popular WYSIWYG HTML editor) have been refactoring its rather legacy JavaScript (the first version came out 17 years ago!) to modern practices.

Joakim Lindkvist

7 JavaScript Design Patterns Every Developer Should Know — This is sort of like a (very) mini version of Addy Osmani’s 2017 book on JS design patterns (which is referenced at the end of the post).

deven rathore

▶  An Introduction to State Machines Using XStateXState is a neat way to work with state machines in JavaScript, Kyle is a neat teacher, and Egghead is a neat platform for unlocking these videos for us too.

Kyle Shevlin

Ride Down Into JavaScript Dependency Hell

AppSignal sponsor

A Collection of Challenging TypeScript Exercises“The goal: Let everyone play with many different TypeScript features and get an overview of TypeScript capabilities and principles.”

Marat Dulin

A Visual Guide to React Mental Models — Different people learn in different ways but good mental models are always valuable and can be helpful if you need to juggle all of the pieces involved in a framework like React.

Obed Parlapiano

Turning Vue Components Into Reusable npm Packages — Outlines how you can reuse Vue components across your projects by automating your process to bundle, test, document, and publish your components.

Sjoerd de voorhoede

???? Code & Tools

jExcel v4: A Vanilla JS Interactive Table / Spreadsheet Control — 4.0 adds support for tabs/workbooks, updating a remote data source with JSON, formula support in a sheet footer, and more. There are lots of demos and examples on the official homepage.

Paul Hodel

Will It CORS? — A handy online tool/wizard for establishing how your (potential) use case will (or won’t!) operate alongside CORS (Cross-Origin Resource Sharing).

HTTP Toolkit

Get Great Visual Feedback & Bug Reports, Even from Non-Technical Folk — Simply click a page element to pin visual feedback with screenshots & metadata. BugHerd = fast and easy bug tracking.

BugHerd sponsor

utfu: Replace Busted Characters From Legacy Text with UTF-8 — Useful when old content contains characters like “— in place of a single quote, and similar legacy text issues.

Daniel Sieradski

Middy 1.0: A Node Middleware Framework for AWS Lambda — Middy’s aim is to make writing serverless functions (hosted on AWS Lambda) easier by providing a familiar middleware abstraction to Node developers.

Luciano Mammino

useWorker() 3.0: A React Hook for Blocking-Free Background Tasks — Makes it easier to throw tasks off to a Web Worker in React.

Alessio Koci

webpack-blocks: Configure webpack using Functional Feature Blocks

Andy Wermke

JZZ: A MIDI Library for Node and the Browser — Send, receive and play MIDI messages from both Node and the browser on Linux, macOS and Windows.

Sema

MDX 1.6: Use JSX in Markdown Documents — This version introduces initial Vue support.

Compositor and Vercel

???? Upcoming Online Events

  • JavaScript Remote Conf 2020 (May 14-15) — Speakers lined up already include Raymond Camden, Christian Heilmann, and Aleksandra Sikora.
  • ESNEXT CONF 2020 (May 18-22) — From the Pika folks (of Snowpack fame). 12 speakers over 5 days so it's a gradual pace.
  • ForwardJS (May 26-29) — A real world event (ForwardJS Ottawa) that has now become a virtual event.
  • CascadiaJS 2020 (September 1-2) — This upcoming online conference is set to take place in September, and the CFP is open now through May 15.




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Jest 26, JS one liners, and comparing Ember to React

#487 — May 8, 2020

Unsubscribe  :  Read on the Web

JavaScript Weekly

Jest 26 Released: The Popular Testing Framework — Jest is a popular testing framework that works with pretty much everything. This release focuses on getting the dependency count and install size down (this causes some breaking changes, unsurprisingly), adds a new fake timer implementation, drops Node 8 support, and initial, experimental ESM support to play with.

Christoph Nakazawa

1LOC: A Collection of One-Line JS Snippets — A neat little collection of vanilla JavaScript one-liners divided into various categories (arrays, date/time, checking objects, DOM work, etc.) You can submit your own for inclusion too.

Nguyen Huu Phuoc

Hardcore Functional Programming in JavaScript — Brian Lonsdorf teaches you functional programming concepts in JavaScript such as pure functions, currying, composition, functors, monads and more.

Frontend Masters sponsor

Debug Anything: The Basics — A six part series (all ready to read now) on debugging your JavaScript and TypeScript code with the debugger built into Visual Studio Code.

Charles Szilagyi

Comparing Ember Octane and React — This is about as detailed a comparison as you could hope for and a demonstration of just how much Ember contributes to the JavaScript ecosystem. Octane really kicks things up a notch for Ember, too.

Chris Garrett

Deno 1.0 is Due Next Week: Here's What You Need to Know — In 2018 Node's creator Ryan Dahl told us 10 Things I Regret About Node.js and revealed a prototype of Deno, a new V8-based runtime, and here's what you need to know about it. Short of time? This two-minute video sums up the biggest wins quickly.

David Else

Our newest newsletter..

Carrying on from the Deno item above, yes, we've started Deno Weekly, a new newsletter dedicated to the newest runtime in the JavaScript/TypeScript world. Issue 2 goes out just after 1.0 is released next week.

Even if you don't stick with Deno long term, feel free to subscribe then unsubscribe at any time — we won't take offence ????

Subscribe to Deno Weekly here or enjoy issue 1 here.

???? Jobs

JavaScript Developer at X-Team (Remote) — Join X-Team and work on projects for companies like Riot Games, FOX, Coinbase, and more. Work from anywhere.

X-Team

Find a Job Through Vettery — Vettery specializes in tech roles and is completely free for job seekers. Create a profile to get started.

Vettery

???? Tutorials

How To Build a Vue Survey App Using Firebase — A step-by-step guide to building a functional survey app using Vue.js and Firebase for both authentication and as a database.

David Atanda

A Brief Look at ES2020's Promise.any — When you need to know when at least 1 promise got resolved among an iterable of Promise objects, Promise.any() is the solution.

Marios Fakiolas

ES2020: Everything You Need to Know — An ES2020 roundup!

Martin McKeaveney

Building a Crossword Puzzle Generator — As a NY Times crossword addict, I love a good crossword, but if you’d rather figure out how to make your computer solve them, be my guest ???? This post guides you on how to approach the problem.

Mitchum

Git Best Practices for SOC 2 Compliance Quick Wins — Get quick wins for your SOC 2 compliance audit, and raise developer productivity at the same time.

Datree.io sponsor

Getting Started with Sapper and SvelteSapper is a Svelte-powered framework.

Chris Boakes

A ES2015+ Cheatsheet — A one-page guide to ES2015+ features based around brief example snippets.

Devhints.io

How to Fix ESLint Errors Upon Save in VS Code — A quick-fire tip.

David Walsh

How to Build a Blog with Next 9.3, Netlify, and Markdown — Learn how to build a Next.js-powered Markdown blog and deploy it to the Netlify platform.

Cassidy Williams

A Canvas Engine Comparison: PixiJS vs Two.js vs Paper.js — A benchmark of three popular 2D rendering engines/drawing APIs. Note: This will tax your system.

SlayLines

???? BTW, if you like videos, we need to shout out Florin Pop's YouTube channel as he's just passed 20k subscribers by posting neat JavaScript videos and live streams nearly every day for the past six months! ???? Lots of great stuff on there for JavaScript developers of all skill levels.

???? Code & Tools

Selecto.js: Make Elements Selectable Within an Area — Let’s say you have a number of elements that represent choices, data, whatever, and you want users to be able to select a subset of them by clicking/pointing and dragging. That’s what this does. Live examples here.

Daybrush (Younkue Choi)

Visual Studio Code April 2020 Released — Probably the most widely used editor in the JavaScript space now and April brings some neat new features like being able to work on GitHub issues within the editor.

Microsoft

Stream Chat API & JavaScript SDK for Custom Chat Apps — Build real-time chat in less time. Rapidly ship in-app messaging with our highly reliable chat infrastructure.

Stream sponsor

Majestic 1.7: A Zero Config GUI for Jest — A tool to help make your JavaScript testing life a little easier. Run npx majestic in the folder of any project that uses Jest to give it a quick try.

Raathi Kugarajan

Pico: Take Browser Screenshots Client-Side with JavaScript — Different from capturing a webpage using Puppeteer or a similar tool in that the screenshot taking happens entirely client side.

Gripeless

React Flow: A Library for Rendering Interactive Graphs — If you have a need to lay out graphs in a visual way and be able to smoothly pan and zoom around such graphs, this is an interesting new library. Live demo here.

Moritz Klack

MongoDB Is Easy. Now Make It Powerful. Free Download for 30 Days.

Studio 3T sponsor

NeutralinoJS: Build Cross-Platform Apps Using JS, HTML and CSS — Sounds just like Electron, right? Not quite. NeutralinoJS use less memory and are smaller as they don’t ship a full browser inside. 1.4.0 just dropped.

Neutralinojs

Slugify 1.0: Simply Turns Strings into URL/Filename-Friendly 'Slugs' — e.g. ‘I ♥ Dogs’ becomes ‘i-love-dogs’

Sindre Sorhus

RxJS Primitives: A Set of Libraries That Provide Operators for RxJS

Tane Piper

⚡️ Quick releases:




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Long-term growth narrative has been set by Sitharaman: BofA's Kaku Nakhate

The government's decision of upholding power purchase agreements as well as the opening up of railways, city gas distribution, and electricity supply to the private sector, are welcome steps




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Budget 2020: NRI tax to only impact India earnings, govt clarifies

The Union Budget had proposed on Saturday that NRIs have to pay up taxes on global earnings, if they're not paying in any other jurisdiction or country, generating much debate




ng

Decoding Budget 2020: Nirmala Sitharaman's fiscal maths gone awry

Slowdown in economic growth has taken a clear toll on revenue growth




ng

Govt has put out a progressive Budget aimed at boosting infra: Sujeet Kumar

It has restored confidence of businesses as well as provided on-ground support that MSMEs need and farmers deserve, Co-founder of Udaan said




ng

LIC listing may take about a year, says Finance Secretary Rajiv Kumar

Kumar said the idea behind the listing of LIC was to "bring in more transparency and allow the company to share gains with its stakeholders"




ng

Budget 2020: Selling pressure on stock market may continue, say experts

On Saturday, the benchmark indices closed near their day's lows, indicating further selling pressure on the following trading day




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Govt very transparent in setting new fiscal deficit target: FM Sitharaman

She further said that many people have been speculating that the fiscal deficit would cross 4%




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Power industry hails proposal for smart prepaid metering across the country

Power ministry has been planning it for two years, but with limited success




ng

RBI MPC starts meeting to decide new rates amid slowdown, rising inflation

The retail inflation that for several months remained in the comfort zone of the central bank has started inching up and crossed the 7 per cent mark during December 2019




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Wanted to keep Budget Speech shorter but ended up breaking own record: FM

In July presenting her maiden Budget, Sitharaman had spoken for 2 hours 17 minutes




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Economy fundamentals strong; markets show faith in Budget 2020: Sitharaman

FM says country's macroeconomic parameters are sound




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Open to tweaking Budget to address concerns of the industry, says FM

Finance ministry to come out with detailed rules on Vivad Se Vishwas Bill in a couple of days




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Objective of kick-starting growth not addressed effectively in Budget: Garg

"All these expenditures are unlikely to be imparting any fresh growth stimulus to the Indian economy," he argued




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Budget disappointing; but fiscal, taxation measures welcome: EAC member

India's GDP growth is expected to slip to a decadal low of 5 per cent this fiscal, pressured by domestic factors like drop in consumption, as well as global issues




ng

Understanding Depression and Distress Among Medical Students

Interview with Laura Weiss Roberts, MD, MA, author of Understanding Depression and Distress Among Medical Students




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Putting the Public Back in Public Reporting of Health Care Quality

Interview with Tara Lagu, MD, MPH, author of Putting the Public Back in Public Reporting of Health Care Quality




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Substituted Interests and Best Judgments: An Integrated Model of Surrogate Decision Making

Interview with Daniel P. Sulmasy, MD, PhD, author of Substituted Interests and Best Judgments: An Integrated Model of Surrogate Decision Making




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Discussing Radiation Risks Associated With CT Scans With Patients

Interview with Mark Otto Baerlocher, MD, author of Discussing Radiation Risks Associated With CT Scans With Patients




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he United States' Engagement in Global Tobacco Control

Interview with Lawrence O. Gostin, JD, author of The United States' Engagement in Global Tobacco Control




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Biosafety Concerns Involving Genetically Modified Mosquitoes to Combat Malaria and Dengue in Developing Countries

Interview with Lawrence O. Gostin, JD, author of Biosafety Concerns Involving Genetically Modified Mosquitoes to Combat Malaria and Dengue in Developing Countries




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Curtailing Diversion and Abuse of Opioid Analgesics Without Jeopardizing Pain Treatment

Interview with Nora D. Volkow, MD, author of Curtailing Diversion and Abuse of Opioid Analgesics Without Jeopardizing Pain Treatment




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Improving Postdischarge Outcomes in Patients Hospitalized for Acute Heart Failure Syndromes

Interview with Mihai Gheorghiade, MD, author of Improving Postdischarge Outcomes in Patients Hospitalized for Acute Heart Failure Syndromes




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Interventions for War-Related Posttraumatic Stress Disorder: Meeting Veterans Where They Are

Interview with Charles Hoge, MD, author of Interventions for War-Related Posttraumatic Stress Disorder: Meeting Veterans Where They Are




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Implementation of Medicare Part D and Nondrug Medical Spending for Elderly Adults With Limited Prior Drug Coverage

Interview with J. Michael McWilliams, MD, Phd, author of Implementation of Medicare Part D and Nondrug Medical Spending for Elderly Adults With Limited Prior Drug Coverage




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Sleep-Disordered Breathing, Hypoxia, and Risk of Mild Cognitive Impairment and Dementia in Older Women

Interview with Katie L. Stone, PhD, author of Sleep-Disordered Breathing, Hypoxia, and Risk of Mild Cognitive Impairment and Dementia in Older Women




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Implementing Accountable Care Organizations: Ten Potential Mistakes and How to Learn From Them

Interview with Stephen M. Shortell, PhD, MPH, MBA, author of Implementing Accountable Care Organizations: Ten Potential Mistakes and How to Learn From Them




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Effect of a Dietary Portfolio of Cholesterol-Lowering Foods Given at 2 Levels of Intensity of Dietary Advice on Serum Lipids in Hyperlipidemia: A Randomized Controlled Trial

Interview with David J. A. Jenkins, MD, author of Effect of a Dietary Portfolio of Cholesterol-Lowering Foods Given at 2 Levels of Intensity of Dietary Advice on Serum Lipids in Hyperlipidemia: A Randomized Controlled Trial




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Quality of Life, Burnout, Educational Debt, and Medical Knowledge Among Internal Medicine Residents

Interview with Colin P. West, MD, PhD, author of Quality of Life, Burnout, Educational Debt, and Medical Knowledge Among Internal Medicine Residents




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Graduated Driver Licensing and Fatal Crashes Involving 16- to 19-Year-Old Drivers

Interview with Scott V. Masten, PhD, author of Graduated Driver Licensing and Fatal Crashes Involving 16- to 19-Year-Old Drivers




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Prediction of Erectile Function Following Treatment for Prostate Cancer

Interview with Martin G. Sanda, MD, author of Prediction of Erectile Function Following Treatment for Prostate Cancer




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Effect of Increasing Doses of Saw Palmetto Extract on Lower Urinary Tract Symptoms: A Randomized Trial

Interview with Kevin T. McVary, MD, author of Effect of Increasing Doses of Saw Palmetto Extract on Lower Urinary Tract Symptoms: A Randomized Trial




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Prevalence and Outcomes of Same-Day Discharge After Elective Percutaneous Coronary Intervention Among Older Patients

Interview with Sunil V. Rao, MD, author of Prevalence and Outcomes of Same-Day Discharge After Elective Percutaneous Coronary Intervention Among Older Patients




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Identification of Chronic Obstructive Pulmonary Disease in Lung Cancer Screening Computed Tomographic Scans

Interview with Pim A. de Jong, MD, PhD, author of Identification of Chronic Obstructive Pulmonary Disease in Lung Cancer Screening Computed Tomographic Scans




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Moderate Alcohol Consumption During Adult Life, Drinking Patterns, and Breast Cancer Risk

Interview with Wendy Y. Chen, MD, MPH, author of Moderate Alcohol Consumption During Adult Life, Drinking Patterns, and Breast Cancer Risk




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Association Between Physician Billing and Cardiac Stress Testing Patterns Following Coronary Revascularization

Interview with Bimal R. Shah, MD, MB, author of Association Between Physician Billing and Cardiac Stress Testing Patterns Following Coronary Revascularization




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Effect of Intracoronary Delivery of Autologous Bone Marrow Mononuclear Cells 2 to 3 Weeks Following Acute Myocardial Infarction on Left Ventricular Function: The LateTIME Randomized Trial

Interview with Jay H. Traverse, MD, author of Effect of Intracoronary Delivery of Autologous Bone Marrow Mononuclear Cells 2 to 3 Weeks Following Acute Myocardial Infarction on Left Ventricular Function: The LateTIME Randomized Trial




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Association Between Valvular Surgery and Mortality Among Patients With Infective Endocarditis Complicated by Heart

Interview with Andrew Wang, MD, author of Association Between Valvular Surgery and Mortality Among Patients With Infective Endocarditis Complicated by Heart Failure




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Association of Antenatal Corticosteroids With Mortality and Neurodevelopmental Outcomes Among Infants Born at 22 to 25 Weeks' Gestation

Interview with Waldemar A. Carlo, MD, author of Association of Antenatal Corticosteroids With Mortality and Neurodevelopmental Outcomes Among Infants Born at 22 to 25 Weeks' Gestation




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Causes of Death Among Stillbirths

Interview with Robert M. Silver, MD, author of Causes of Death Among Stillbirths




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Prostate Cancer Screening-The Evidence, the Recommendations, and the Clinical Implications

Interview with Roger Chou, MD, author of Prostate Cancer Screening-The Evidence, the Recommendations, and the Clinical Implications




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ADHD Medications and Risk of Serious Cardiovascular Events in Young and Middle-aged Adults

Interview with Laurel A. Habel, PhD, author of ADHD Medications and Risk of Serious Cardiovascular Events in Young and Middle-aged Adults




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Where Are the Health Care Cost Savings?

Interview with Ezekiel J. Emanuel, MD, PhD, author of Where Are the Health Care Cost Savings?




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Effect of Dietary Protein Content on Weight Gain, Energy Expenditure, and Body Composition During Overeating: A Randomized Controlled Trial

Interview with George A. Bray, MD, author of Effect of Dietary Protein Content on Weight Gain, Energy Expenditure, and Body Composition During Overeating: A Randomized Controlled Trial




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Universal Screening and Drug Treatment of Dyslipidemia in Children and Adolescents

Interview with Frederick P. Rivara, MD, MPH, author of Universal Screening and Drug Treatment of Dyslipidemia in Children and Adolescents




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Antiplatelet Therapy With Cangrelor in Patients Undergoing Cardiac Surgery: A Randomized Controlled Trial

Interview with Eric J. Topol, MD, author of Bridging Antiplatelet Therapy With Cangrelor in Patients Undergoing Cardiac Surgery: A Randomized Controlled Trial




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Variability in Reexcision Following Breast Conservation Surgery

Interview with Laurence E. McCahill, MD, author of Variability in Reexcision Following Breast Conservation Surgery