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Interfacing human induced pluripotent stem cell-derived neurons with designed nanowire arrays as a future platform for medical applications

By pubs.rsc.org
Published On ::

Biomater. Sci., 2020, 8,2434-2446
DOI: 10.1039/D0BM00182A, Paper
Jann Harberts, Undine Haferkamp, Stefanie Haugg, Cornelius Fendler, Dennis Lam, Robert Zierold, Ole Pless, Robert H. Blick
Nanostructured substrates such as nanowire arrays form a powerful tool for building next-generation medical devices.
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A novel peptide targeting gastrin releasing peptide receptor for pancreatic neoplasm detection

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Biomater. Sci., 2020, 8,2682-2693
DOI: 10.1039/D0BM00162G, Paper
Yuanbiao Tu, Ji Tao, Fang Wang, Peifei Liu, Zhihao Han, Zhaolun Li, Yi Ma, Yueqing Gu
The designed novel peptide GB-6 with targeted GRPR-binding possesses more favorable pharmacokinetic properties and metabolic stability, as well as superior tumor-targeting ability in pancreatic cancer models, relative to BBN7–14.
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An intelligent vancomycin release system for preventing surgical site infections of bone tissues

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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00255K, Paper
Yuan Li, Guang Li, Xiaoling Sha, Litao Li, Kuo Zhang, Daohong Liu, Yanfei Hao, Xu Cui, Lei Wang, Hao Wang
An intelligent anti-bacterial system can be constructed on implants during surgery.
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Outstanding Reviewers for Biomaterials Science in 2019

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Biomater. Sci., 2020, 8,2343-2343
DOI: 10.1039/D0BM90031A, Editorial

We would like to take this opportunity to highlight the Outstanding Reviewers for Biomaterials Science in 2019, as selected by the editorial team for their significant contribution to the journal.
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A multifunctional metal-biopolymer coordinated double network hydrogel combined with multi-stimulus responsiveness, self-healing, shape memory and antibacterial properties

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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00425A, Paper
Kun Yan, Feiyang Xu, Chunyu Wang, Yingying Li, Yuanli Chen, Xiufang Li, Zhentan Lu, Dong Wang
A universal, straightforward macroscale assembly technology has been presented for fabrication of polysaccharide-based multifunctional DN gels based on metal coordination chemistry.
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Modulating neutrophil extracellular traps for wound healing

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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00355G, Paper
Tejinder Kaur, Shweta Dumoga, Veena Koul, Neetu Singh
An alginate-GelMa scaffold for modulating neutrophil extracellular traps using a PAD4 inhibitor could be a novel therapeutic approach for wound healing.
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A super-stretchable, self-healing and injectable supramolecular hydrogel constructed by a host–guest crosslinker

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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00290A, Paper
Yang Zhou, Yuanhao Zhang, Zhaobo Dai, Fang Jiang, Jia Tian, Weian Zhang
Supramolecular hydrogels based on host–guest interactions have drawn considerable attention due to their unique properties and promising applications.
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Coupling PEG-LZM Polymer Network with Polyphenol Yields Suturable Biohydrogel for Tissue Patching

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Biomater. Sci., 2020, Accepted Manuscript
DOI: 10.1039/D0BM00429D, Paper
Haoqi Tan, Junjie Sun, Dawei Jin, Jialin Song, Miao Lei, Artem Antoshin, Xin Chen, Meng Yin, Xue Qu, Changsheng Liu
Poor mechanical performances severely limit the application of hydrogel in vivo, for example, it is difficult to perform a very common suturing operation on hydrogel during surgery. There is a...
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Optically controlled hybrid metamaterial of plasmonic spiky gold inbuilt graphene sheets for bimodal imaging guided multimodal therapy

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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00312C, Paper
Kunnumpurathu Jibin, Jayaram S. Prasad, Giridharan Saranya, Sachin J. Shenoy, Kaustabh K. Maiti, Ramapurath S. Jayasree
Gold–graphene nanohybrid for simultaneous dual-imaging guided triple therapy as a new paradigm in light-triggered cancer theranostics. The material demonstrates excellent therapeutic efficacy and treatment monitoring features.
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Surface engineering of titanium alloy using metal-polyphenol network coating with magnesium ions for improved osseointegration

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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00566E, Paper
Sangmin Lee, Yun-Young Chang, Jinkyu Lee, Sajeesh Kumar Madhurakkat Perikamana, Eun Mi Kim, Yang-Hun Jung, Jeong-Ho Yun, Heungsoo Shin
Although titanium-based implants are widely used in orthopedic and dental clinics, improved osseointegration at the bone–implant interface is still required.
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Effective intracellular delivery of bevacizumab via PEGylated polymeric nanoparticles targeting CD44v6 receptor in colon cancer cells

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Published On ::

Biomater. Sci., 2020, Accepted Manuscript
DOI: 10.1039/D0BM00556H, Paper
Ana Baião, Flávia Sousa, Ana Oliveira, Carla Oliveira, Bruno Sarmento
Colorectal cancer (CRC) is one of the most incident and mortal cancers in the world, mainly due to its metastatic and metabolic ability. CD44 receptor isoform containing exon 6 (CD44v6)...
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miR-140-5p mediates bevacizumab-induced cytotoxicity to cardiomyocytes by targeting the VEGFA/14-3-3γ signal pathway

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Toxicol. Res., 2019, 8,875-884
DOI: 10.1039/C9TX00100J, Paper
Xuan-Ying Chen, Wei-Lin Huang, Xiao-Ping Peng, Yan-Ni Lv, Jun-He Li, Jian-Ping Xiong
Bevacizumab (BVZ) is a widely investigated angiogenesis inhibitor in cancer patients. Although the anti-tumor effects has been verified, cardiotoxicity may be the most serious side-effect for BVZ.
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Comment on “Acetylcysteine in paracetamol poisoning: a perspective of 45 years of use” by D. N. Bateman and J. W. Dear, Toxicol. Res., 2019, 8, 489

By pubs.rsc.org
Published On ::

Toxicol. Res., 2019, 8,1057-1058
DOI: 10.1039/C9TX00158A, Comment
Michael E. Mullins, Mark C. Yarema, Marco L. A. Sivilotti, Margaret Thompson, D. Adam Algren, Michael C. Beuhler, Christopher P. Holstege
We point out an acetylcysteine protocol that a previous article (D. N. Bateman and J. W. Dear, Toxicol. Res., 2019, 8, 489–498) overlooked.
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Characteristic synergistic cytotoxic effects toward cells in graphene oxide dressing with cadmium and copper ions

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Toxicol. Res., 2019, 8,908-917
DOI: 10.1039/C9TX00146H, Paper
Yiyang Dong, Yulin Chang, Haidi Gao, Victoria Arantza León Anchustegui, Qiang Yu, Haifang Wang, Jia-Hui Liu, Shihui Wang
Cadmium ions exerted synergistic toxic effects with graphene oxide on Hela cells.
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Gynura divaricata ameliorates hepatic insulin resistance by modulating insulin signalling, maintaining glycolipid homeostasis and reducing inflammation in type 2 diabetic mice

By pubs.rsc.org
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Toxicol. Res., 2019, 8,928-938
DOI: 10.1039/C9TX00191C, Paper
Xuan Dong, Shu-Xiang Zhao, Bing-Qing Xu, Yu-Qing Zhang
Oral lyophilized powder of Gynura divaricata, an edible medicinal plant, can alleviate both hyperglycaemia and hepatic insulin resistance in type 2 diabetic mice.
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Lipoic acid antagonizes paraquat-induced vascular endothelial dysfunction by suppressing mitochondrial reactive oxidative stress

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Toxicol. Res., 2019, 8,918-927
DOI: 10.1039/C9TX00186G, Paper
Li Pang, Ping Deng, Yi-dan Liang, Jing-yu Qian, Li-Chuan Wu, Ling-ling Yang, Zheng-ping Yu, Zhou Zhou
α-Lipoic acid antagonizes paraquat toxicity.
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Reply to the ‘Comment on “Acetylcysteine in paracetamol poisoning: a perspective of 45 years of use”’ by M. E. Mullins, M. C. Yarema, M. L. A. Sivilotti, M. Thompson, D. A. Algren, M. C. Beuhler and C. P. Holstege, Toxicol. Res., 2019, 8, DOI: 10.1039/C9T

By pubs.rsc.org
Published On ::

Toxicol. Res., 2019, 8,1059-1059
DOI: 10.1039/C9TX00216B, Comment
Open Access
D. Nicholas Bateman, James W. Dear
Mullins et al. made a comment on our article (DOI: 10.1039/C9TX00002J) stating they noticed the omission of the one-bag, standard concentration protocol which is shared by several centers in North America when we discussed IV acetylcysteine protocols.
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Biogenic Aspergillus tubingensis silver nanoparticles’ in vitro effects on human umbilical vein endothelial cells, normal human fibroblasts, HEPG2, and Galleria mellonella

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Toxicol. Res., 2019, 8,789-801
DOI: 10.1039/C9TX00091G, Paper
Cristiane Angélica Ottoni, Durvanei Augusto Maria, Priscila Jane Romano de Oliveira Gonçalves, Welington Luiz de Araújo, Ana Olívia de Souza
Biogenic silver nanoparticles are ecofriendly and offers valuable possibilities of applications in several industrial areas.
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Astilbin attenuates cerebral ischemia/reperfusion injury by inhibiting the TLR4/MyD88/NF-κB pathway

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Published On ::

Toxicol. Res., 2019, 8,1002-1008
DOI: 10.1039/C9TX00222G, Paper
Jing Li, Zhaowei Gu, Yue Liu, Yu Wang, Min Zhao
Ischemic stroke is the second most common cause of death worldwide and cerebral ischemia/reperfusion (I/R) injury also leads to serious tissue damage.
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Nanoparticle induced barrier function assessment at liquid–liquid and air–liquid interface in novel human lung epithelia cell lines

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Published On ::

Toxicol. Res., 2019, 8,1016-1027
DOI: 10.1039/C9TX00179D, Paper
Open Access
Lars Leibrock, Sandra Wagener, Ajay Vikram Singh, Peter Laux, Andreas Luch
To answer questions about nanoparticle toxicity, translocation and biokinetics following inhalation exposure, in vitro models should have functional barrier properties to mimic the in vivo situation as closely as possible.
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Phytochemicals protect L02 cells against hepatotoxicity induced by emodin via the Nrf2 signaling pathway

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Toxicol. Res., 2019, 8,1028-1034
DOI: 10.1039/C9TX00220K, Paper
Yan Yan, Kang Wang, Xu Tang, Jun-feng Gao, Bin-yu Wen
Dihydromyricetin (DMY), hyperoside and silybin are phytochemicals that belong to a class called flavonoids, and they have been used in liver protection pharmaceutical preparations, but the specific mechanism of these chemicals is still unclarified.
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Amarinder Singh asks administration to ensure welfare of migrant workers

By www.business-standard.com
Published On :: Fri, 08 May 2020 17:53:00 +0530

The chief minister asked the industry ministry to "aggressively" pursue the development of the four industrial parks already announced by the state government in the budget for this fiscal.


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Govt hikes market borrowing limit by over 50% to Rs 12 trillion

By www.business-standard.com
Published On :: Fri, 08 May 2020 20:04:00 +0530

The government resorts to market borrowing to make up for the mismatch between its revenue and expenditure.


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Vizag gas leak: NGT orders LG Polymers to deposit Rs 50 cr pending probe

By www.business-standard.com
Published On :: Fri, 08 May 2020 20:07:00 +0530

NGT bench set up fact-finding committee, to be headed by former AP High Court judge


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Gujarat eases labour laws, offers land to firms shifting base from China

By www.business-standard.com
Published On :: Fri, 08 May 2020 20:28:00 +0530

The state government also offered land and infrastructure for companies and projects that were looking to shift base from China to other destinations


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Govt must work to revive consumption, not worry about rating: Rahul Gandhi

By www.business-standard.com
Published On :: Fri, 08 May 2020 20:44:00 +0530

Congress wants lockdown lifted across country on May 18, save hotspots; Gandhi urges Centre to make citizens 'psychologically' prepared to for lockdown exit


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Govt hikes borrowing limit by over 50% to Rs 12 trn as virus grips economy

By www.business-standard.com
Published On :: Fri, 08 May 2020 20:56:00 +0530

Sources say the Centre has asked RBI to do whatever to keep yields in check, which may result in massive secondary market bond purchases


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Lockdown period not to be counted for determining residency of NRIs: CBDT

By www.business-standard.com
Published On :: Fri, 08 May 2020 23:12:00 +0530

There were apprehensions that this extended stay could lead to these individuals becoming Indian residents as per Section 6 of the Income Tax Act


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Working closely with states on labour reforms to help industry: Centre

By www.business-standard.com
Published On :: Fri, 08 May 2020 23:24:00 +0530

The Confederation of Indian Industry (CII) suggested to the Labour Ministry to "direct workers to join back to their workplace" by issuing a circular


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Additional borrowing to widen fiscal deficit, but help govt perk up economy

By www.business-standard.com
Published On :: Fri, 08 May 2020 23:50:00 +0530

He did not think that the move will crowd out borrowings of the private sector, saying demand of the government and the private sector are not contradictory in these circumstances


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Sitharaman launches two exchanges to take on offshore currency market

By www.business-standard.com
Published On :: Sat, 09 May 2020 00:20:00 +0530

The launch comes amid the world's most expansive coronavirus lockdown, which has crippled businesses and hurt trading volumes in the country's financial markets.


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Lockdown worsening poverty levels among workers in informal economy: ILO

By www.business-standard.com
Published On :: Sat, 09 May 2020 13:07:00 +0530

In high-income countries, relative poverty levels among informal workers are estimated to increase by 52 percentage points


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Assam latest to go for labour reforms, plans raising work hours by 50%

By www.business-standard.com
Published On :: Sat, 09 May 2020 15:08:00 +0530

Unlike other BJP-ruled states, it isn't doing away with most existing laws, but seeks to introduce fixed-term employment to facilitate direct hiring of contract labour by firms


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UP steps up efforts to reach out to 74 global firms looking to exit China

By www.business-standard.com
Published On :: Sat, 09 May 2020 15:38:00 +0530

European Business Group hails covid-19-induced labour reforms in UP; state goes online to connect with five nations and companies like Microsoft, Dow and IBM and showcase investment opportunities


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Miners want mandatory capex rule relaxed as workers stay away fearing Covid

By www.business-standard.com
Published On :: Sat, 09 May 2020 17:43:00 +0530

None of the merchant mines in Odisha whose lease validity expired by March 31 has been able to restart. Though the successful bidders have got LoI, they awaiting formal vesting orders


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Probing permanent dipoles in CdSe nanoplatelets with transient electric birefringence

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Nanoscale, 2020, Advance Article
DOI: 10.1039/D0NR00884B, Paper
Ivan Dozov, Claire Goldmann, Patrick Davidson, Benjamin Abécassis
Transient electric birefringence experiments with colloidal suspensions of zinc-blende CdSe semiconducting nanoplatelets prove that these particles bear a large ground-state electric dipole despite the cubic structure of bulk zinc-blende CdSe.
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RGD functionalized chitosan nanoparticle mediated targeted delivery of raloxifene selectively suppresses angiogenesis and tumor growth in breast cancer

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Nanoscale, 2020, Advance Article
DOI: 10.1039/C9NR10673A, Paper
Amit S. Yadav, N. Naga Venkata Radharani, Mahadeo Gorain, Anuradha Bulbule, Dattatrya Shetti, Gaurab Roy, Thejus Baby, Gopal C. Kundu
Peptide functionalized pH sensitive raloxifene-chitosan nanoparticles with high biocompatibility synergistically inhibit tumor growth and angiogenesis in breast cancer.
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Efficient sub-15 nm cubic-phase core/shell upconversion nanoparticles as reporters for ensemble and single particle studies

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Nanoscale, 2020, Advance Article
DOI: 10.1039/D0NR02172E, Paper
Meiling Tan, Melissa-Jane Monks, Dingxin Huang, Yongjun Meng, Xuewen Chen, Ying Zhou, Shuang-Fang Lim, Christian Würth, Ute Resch-Genger, Guanying Chen
A set of sub-15 nm ytterbium-enriched α-NaYbF4:Er3+@CaF2 core/shell upconversion nanoparticles have been developed for both ensemble- and single particle-level imaging studies, presenting a high quantum yield of 0.77% at a low saturation power density of 110 W cm−2.
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Conductive-bridging random-access memories for emerging neuromorphic computing

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Nanoscale, 2020, Advance Article
DOI: 10.1039/D0NR01671C, Review Article
Jun-Hwe Cha, Sang Yoon Yang, Jungyeop Oh, Shinhyun Choi, Sangsu Park, Byung Chul Jang, Wonbae Ahn, Sung-Yool Choi
This review covers CBRAM-based artificial synapses and neurons towards emerging computing applications from the operation principles of CBRAMs to state-of-the-art experimental demonstrations.
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Dual-sensitized Upconversion-assisted, Triple-band Absorbing Luminescent Solar Concentrators

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Nanoscale, 2020, Accepted Manuscript
DOI: 10.1039/D0NR01008A, Paper
Sung Kyung Nam, Kiwon Kim, Ji-Hwan Kang, Jun Hyuk Moon
Luminescent solar concentrator-photovoltaic systems (LSC-PV) harvest solar light by using transparent photoluminescent plates, which is expected to be particularly useful for building-integrated PV applications. LSC panels that absorb multiple wavelength...
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Dy2@C79N: A New Member of Dimetalloazafullerenes with Strong Single Molecular Magnetism

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Nanoscale, 2020, Accepted Manuscript
DOI: 10.1039/D0NR02519D, Paper
Yuanyuan Wang, Jin Xiong, Jie Su, Zi-Qi Hu, Fang Ma, Rong Sun, Xue-You Tan, Hao-Ling Sun, Bingwu Wang, Zujin Shi, Song Gao
Enhancing the exchange interaction between magnetic ions is a long-term target in molecular magnetism. Endohedral metallofullerenes (EMFs) provide a possibility for achieving such a goal by imprisoning multiple magnetic centers...
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Multi-praseodymium-and-tungsten bridging octameric tellurotungstate and its 2D honeycomb composite film for detecting estrogen

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Nanoscale, 2020, Accepted Manuscript
DOI: 10.1039/D0NR01901A, Paper
Yan Zhang, Jun JIang, Yifan Liu, Pan Li, Yong Liu, Lijuan Chen, Junwei Zhao
Under coordination driving force of tungsten and rare-earth (RE) bridges, we synthesized a novel giant multi-tungsten-and-RE—bridging octameric tellurotungstate (TT) [H2N(CH3)2]16K8Na6H10[Pr8(H2O)20W16O48][B-α-TeW9O33]8·70H2O (1) in CH3CN-H2O mixed solvent. The cluster anion {[Pr8(H2O)20W16O48][B-α-TeW9O33]8}40– features...
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Facile fabrication of sponge-like porous micropillar arrays via an electrochemical process

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Nanoscale, 2020, Advance Article
DOI: 10.1039/D0NR01518K, Paper
Deyin Zheng, Chang-Hwan Choi, Xin Zhao, Guangyi Sun
Highly ordered and aligned pore structures perpendicular to the exposed surfaces are achieved on the surfaces of 3D Si microstructures.
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Plasma-assisted filling electron beam lithography for high throughput patterning of large area closed polygon nanostructures

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Nanoscale, 2020, Advance Article
DOI: 10.1039/D0NR01032D, Paper
You Sin Tan, Hailong Liu, Qifeng Ruan, Hao Wang, Joel K. W. Yang
The PFEBL process allows enhancement of electron beam writing efficiency for patterning of closed polygon structures using a post-exposure plasma treatment.
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Proton exchange membrane with plasmon-active surface for enhancement of fuel cell effectivity

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Published On ::

Nanoscale, 2020, Accepted Manuscript
DOI: 10.1039/D0NR00295J, Paper
Roman Elashnikov, Kristina Zahorjanova, Elena Miliutina, Zdenka Kolska, Miroslav Cieslar, Václav Švorčík, Oleksiy Lyutakov
The action of fuel cells with proton-exchanged membrane (PEM) requires the implementation of hydrogen oxidation reaction (HOR) and oxygen reduction reaction (ORR) on the opposite sides of PEM. Recently, based...
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Mechanistic Insight in Site-selective and Anisotropic Etching of Prussian Blue Analogues toward Designable Complex Architectures for Efficient Energy Storage

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Published On ::

Nanoscale, 2020, Accepted Manuscript
DOI: 10.1039/D0NR02241A, Paper
Hai Xu, Xi Zhao, Chenyang Yu, Yue Sun, Zengyu Hui, Ruicong Zhou, Jialu Xue, Henghan Dai, Yue Zhao, Lumin Wang, Yujiao Gong, Jin Yuan Zhou, Jianing An, Qiang Chen, Gengzhi Sun, Wei Huang
Engineering coordination compounds, e.g., prussian blue (PB) and its analogues (PBAs), with designable complex nanostructures via chemical etching holds great opportunities for improving energy storage performances by adjusting topological geometry,...
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Correction: Anomalous polarization dependence of Raman scattering and crystallographic orientation of black phosphorus

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Published On ::

Nanoscale, 2020, Advance Article
DOI: 10.1039/D0NR90098B, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Jungcheol Kim, Jae-Ung Lee, Jinhwan Lee, Hyo Ju Park, Zonghoon Lee, Changgu Lee, Hyeonsik Cheong
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Pristine Graphene Induces Innate Immune Training

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Nanoscale, 2020, Accepted Manuscript
DOI: 10.1039/C9NR09661B, Paper
Filipa Lebre, John B Boland, Pedro Gouveia, Aoife Gorman, Mimmi Lundahl, Fergal J O'Brien, Jonathan N Coleman, Ed Lavelle
Graphene-based materials are of increasing interest for their potential use in biomedical applications. However, there is a need to gain a deeper understanding of how graphene modulates biological responses before...
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Functional nanoarrays for investigating stem cell fate and function

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Published On ::

Nanoscale, 2020, 12,9306-9326
DOI: 10.1039/C9NR10963C, Review Article
Jin-Ho Lee, Jeffrey Luo, Hye Kyu Choi, Sy-Tsong Dean Chueng, Ki-Bum Lee, Jeong-Woo Choi
An overview of the recent progress of nanoarray synthesis and applications for controlling stem cell fate and monitoring live cell functions.
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Self-responsive co-delivery system for remodeling tumor intracellular microenvironment to promote PTEN-mediated anti-tumor therapy

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Nanoscale, 2020, 12,9392-9403
DOI: 10.1039/D0NR00563K, Paper
Yifei Wang, Ruiting Wang, Sixuan Wu, Jingyi An, Yan Liang, Lin Hou, Zhenzhong Zhang
Delivering the pten gene into tumor cells to reacquire PTEN functionality is considered to be an attractive method for cancer treatment.
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