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Nanoscopic visualization of microgel-immobilized cytochrome P450 enzymes and their local activity

Nanoscale, 2024, 16,20194-20201
DOI: 10.1039/D4NR03435J, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Lukas Schubert, Chiara Nenninger, Maximilian Nöth, Thomke Belthle, Robert Dirk de Lange, Andrij Pich, Ulrich Schwaneberg, Dominik Wöll
The distribution and local catalytic activity of Cytochrome P450 enzymes immobilized in microgels by electrostatic interaction has been determined with a combination of in situ super-resolution fluorescence microscopy experiments.
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Rationalization of the light-induced electron injection mechanism in a model 1D ZnO nanowire-dye complex: insights from real-time TD-DFTB simulations

Nanoscale, 2024, 16,20280-20287
DOI: 10.1039/D3NR06557J, Paper
Dalma M. Márquez, Carlos R. Lien-Medrano, Germán J. Soldano, Cristián G. Sánchez
Zinc oxide nanowires (ZnO NWs) possess a unique one-dimensional (1D) morphology that offers a direct pathway for charge transport.
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Folic acid-targeted redox responsive polylactic acid-based nanoparticles co-delivering pirarubicin and salinomycin suppress breast cancer tumor growth in vivo

Nanoscale, 2024, 16,20131-20146
DOI: 10.1039/D4NR02365J, Paper
Priya Gupta, Ankushi Bansal, Harshdeep Kaur, Mohd Anees, Neetu Singh, Harpal Singh
Schematic illustration of design, administration, and mechanism of action of Pira/Sal dual-loaded FA-conjugated redox responsive [S-(PLA-b-PEG-CONH)]2 block copolymeric nanoparticles.
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“Sergeants-and-soldiers” principle in the synthesis of intrinsically chiral Au13 clusters

Nanoscale, 2024, Advance Article
DOI: 10.1039/D4NR03810J, Paper
Open Access
Katsuya Mutoh, Sonomi Kawakita, Teppei Yahagi, Takuya Nakashima
Single chiral ligand coordination effectively deracemizes intrinsically chiral Au13 clusters with binary mixed ligands of chiral and achiral diphosphines.
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Glycosylated AIE-active Fe (III) photosensitizer activated by tumor microenvironment for synergistic type I photodynamic and chemodynamic therapy

Nanoscale, 2024, Accepted Manuscript
DOI: 10.1039/D4NR03871A, Paper
Gai-li Feng, Wei Zhou, Jinping Qiao, Guang-Jian Liu, Guo-Wen Xing
Photodynamic therapy (PDT) and chemodynamic therapy (CDT) are both promising cancer treatments to inhibit tumor cells by generating highly cytotoxic reactive oxygen species (ROS). Herein, we report a novel tumor...
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Refined Design of DNA Logic Gate for Implementing DNA-based Three-level Circuit

Nanoscale, 2024, Accepted Manuscript
DOI: 10.1039/D4NR03606A, Paper
Yuanpeng Zhang, Bei Yan, Xingge Li, Huan Liu, Xiao Liu, Xianjin Xiao, Zenghui Mao, Zhihao Ming
DNA computing circuits are favored by researchers due to their high density, high parallelism, and biocompatibility. However, compared with electronic circuits, current DNA circuits have significant errors in understanding the...
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Macroscopic chiral symmetry breaking in gelation of Fmoc-amino acids: homochiral selective secondary nucleation promoted by the choice of solvent or stirring

Nanoscale, 2024, Advance Article
DOI: 10.1039/D4NR04011B, Communication
Kentaro Tashiro
Homochiral selective secondary nucleation, promoted by the choice of solvent or stirring, was suggested as the key process for the emergence of macroscopic chiral symmetry breaking in the gelation of Fmoc amino acids.
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Enhanced antifungal activity of siRNA-loaded anionic liposomes against the human pathogenic fungus Aspergillus fumigatus

Nanoscale, 2024, Advance Article
DOI: 10.1039/D4NR03225J, Communication
Open Access
Yidong Yu, Theresa Vogel, Sina Hirsch, Jürgen Groll, Krystyna Albrecht, Andreas Beilhack
Application of anionic liposomes co-loaded with amphotericin B and siRNA demonstrates a temporary antifungal effect lasting 3–4 days, highlighting their therapeutic potential.
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Photoemission spectroscopy and microscopy for Ta@Si16 superatoms and their assembled layers

Nanoscale, 2024, Advance Article
DOI: 10.1039/D4NR02778G, Paper
Open Access
Masahiro Shibuta, Tsutomu Ohta, Toshiaki Kamoshida, Kana Yamagiwa, Hironori Tsunoyama, Tomoya Inoue, Tsugunosuke Masubuchi, Atsushi Nakajima
An alkaline-like Ta-encapsulating Si16 superatom film was fabricated on a C60 substrate. Charge transfer between Ta@Si16 and C60 lowers the work function. In the multilayer film, the central Ta atom's positive charge is compensated by the Si16 cage.
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Polylactic acid/chitosan-IKVAV Janus film serving as a dual functional platform for spinal cord injury repair

Nanoscale, 2024, Advance Article
DOI: 10.1039/D4NR02248C, Paper
Liyang Yu, Haoyong Jin, He Xia, Xiaoxiong Wang, Liang Wang, Dezheng Li, Jiangli Zhao, Yuanhua Sang, Jichuan Qiu, Ning Lu, Hong Liu, Ning Yang
Schematic showing the PLA/CS-IKVAV Janus film for promoting neuronal differentiation and SCI repair.
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Electrochemical chiral recognition of tryptophan enantiomers by using chiral polyaniline and β-CD-MOF

Nanoscale, 2024, Advance Article
DOI: 10.1039/D4NR02854F, Paper
Jiamin Liang, Yuxin Song, Huan Xing, Liang Ma, Fengxia Wang, Mingfang Zhang, Hongli Zhang, Gang Zou, Guang Yang
A electrochemical sensor for the chiral recognition of Trp based on chiral polyaniline (D-PANI) and β-CD-MOF was designed. It displayed higher affinity of L-Trp, and the oxidation peak current ratio (IL/ID) of DPV could be reached at 2.26.
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A liposome-based assay for cancer biomarker detection: exploring the correlation between platelet-derived microvesicles and NSCLC-associated miRNAs

Nanoscale, 2024, Advance Article
DOI: 10.1039/D4NR03704A, Paper
Mohamed Aimene Benariba, Kanza Hannachi, Sha Zhu, Yuting Zhang, Xiaoli Wang, Nandi Zhou
This research reveals a significant correlation between PMVs and their associated miRNA. Additionally, the liposome-based assay demonstrates enhanced sensitivity with calcium-induced platelet activation.
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Electrode Informatics Accelerated Optimization for Catalyst Layer Key Parameters in Direct Methanol Fuel Cells

Nanoscale, 2024, Accepted Manuscript
DOI: 10.1039/D4NR03026E, Paper
Lishou Ban, Danyang Huang, Yanyi Liu, Pengcheng Liu, Xihui Bian, Kaili Wang, Yifan Liu, Xijun Liu, Jia He
As the core component of direct methanol fuel cell, the catalyst layer plays the key role of material, proton and electron transport channels. However, due to the complexity of its...
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Emerging chiral sulfur-based nanomaterials for chiroptical applications

Nanoscale, 2024, Advance Article
DOI: 10.1039/D4NR03736G, Review Article
Hammad Hasan, Md Ifzal Azhar, Santosh Kumar Behera, Md Palashuddin Sk
This review covers fundamental principles and techniques for measuring chiral properties as well as the synthesis of chiral sulfur-based nanomaterials, their optical and chiroptical properties, and possible applications.
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Factors influencing the chiral imprinting in perovskite nanoparticles

Nanoscale, 2024, Advance Article
DOI: 10.1039/D4NR03329A, Minireview
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Nazifa Tabassum, Brian P. Bloom, Gouranga H. Debnath, David H. Waldeck
This work discusses the imprinting of optoelectronic chirality on hybrid-organic inorganic perovskites, which are a new class of chiral nanomaterials for manipulation and control of spin polarized current and circularly polarized light.
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Expression of concern: Iron oxide magnetic nanoparticles with versatile surface functions based on dopamine anchors

Nanoscale, 2024, Advance Article
DOI: 10.1039/D4NR90209B, Expression of Concern
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Mykola Mazur, Alexandre Barras, Victor Kuncser, Andrei Galatanu, Vladimir Zaitzev, Kostiantyn V. Turcheniuk, Patrice Woisel, Joel Lyskawa, William Laure, Aloysius Siriwardena, Rabah Boukherroub, Sabine Szunerits
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Optimization of hair follicle spheroids for hair-on-a-chip

Biomater. Sci., 2024, 12,1693-1706
DOI: 10.1039/D3BM02012F, Paper
Subin Jeong, Hyeon-Min Nam, Gun Yong Sung
We report spheroids prepared by injecting LEF1 and Wnt1 into DPCs via transfection and then adding KCs and HUVECs. Through SEM, we observed a part extending outward from the TK and TKH surfaces, as indicated by white arrows.
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Bioinspired ginsenoside Rg3 PLGA nanoparticles coated with tumor-derived microvesicles to improve chemotherapy efficacy and alleviate toxicity

Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM00159A, Paper
Shulei Zhang, Bo Zheng, Yiqi Wei, Yuhao Liu, Lan Yang, Yujiao Qiu, Jing Su, Mingfeng Qiu
Breast cancer, a pervasive malignancy affecting women, demands a diverse treatment approach including chemotherapy, radiotherapy, and surgical interventions.
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Telomerase: a nexus between cancer nanotherapy and circadian rhythm

Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM00024B, Minireview
Pramit Kumar Ghosh, Maddila Jagapathi Rao, Chandra Lekha Putta, Sandipan Ray, Aravind Kumar Rengan
The use of nanoparticles for identifying and suppressing telomerase presents promising opportunities for anticancer strategies, particularly in relation to circadian regulation.
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Correction: ECM-based bioadhesive hydrogel for sutureless repair of deep anterior corneal defects

Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM90027H, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Safieh Boroumand, Faraz Sigaroodi, Seyed Mohsen Ahmadi Tafti, Keyvan Khoshmaram, Masoud Soleimani, Mohammad-Mehdi Khani
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Correction: Hybrid protein microspheres and their responsive release behaviors and inhibitory effects on melanin synthesis

Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM90029D, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Ee Taek Hwang, Yeahwa Yoon, Ka Ram Kim, Chan Hee Lee, Kyung Chan Jeon, Ji Ho Min, Jae Won Lee, Jangyong Kim
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Macrophage membrane-camouflaged nanoclusters of ultrasmall iron oxide nanoparticles for precision glioma theranostics

Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM00357H, Paper
Bin Zhang, Rui Yang, Hongwei Yu, Yamin Peng, Haoyu Huang, Meera Moydeen Abdul Hameed, Han Wang, Guixiang Zhang, Mohamed EL-Newehy, Mingwu Shen, Xiangyang Shi, Shaojun Peng
Macrophage membrane-camouflaged nanoclusters of ultrasmall iron oxide nanoparticles can be developed to cross the blood–brain barrier for magnetic resonance imaging and chemo/chemodynamic therapy.
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Liquid–liquid phase separation-inspired design of biomaterials

Biomater. Sci., 2024, 12,1943-1949
DOI: 10.1039/D3BM02008H, Minireview
Yang Song
Biological liquid–liquid phase separation (LLPS) provides novel insights for the assembly of biomaterials with tailored structure and intrinsic functionality.
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Transplantation of a bioengineered tissue patch promotes uterine repair in the sheep

Biomater. Sci., 2024, 12,2136-2148
DOI: 10.1039/D3BM01912H, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Edina Sehic, Lucía de Miguel Gómez, Hardis Rabe, Emy Thorén, Ingigerdur Gudmundsdottir, Mihai Oltean, Randa Akouri, Mats Brännström, Mats Hellström
Innovative bioengineering strategies utilizing extracellular matrix (ECM) based scaffolds derived from decellularized tissue offer new prospects for restoring damaged uterine tissue.
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Optimization of lipid assisted polymeric nanoparticles for siRNA delivery and cancer immunotherapy

Biomater. Sci., 2024, 12,2057-2066
DOI: 10.1039/D3BM02071A, Paper
Song Lin, Houjin Jing, Xiaojiao Du, Xianzhu Yang, Jun Wang
A siRNA delivery system was developed using clinically approved mPEG-b-PLGA, cationic lipid and ionizable lipid for siRNA delivery and cancer immunotherapy.
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Collagen / polyester-polyurethane porous scaffolds for use in meniscal repair

Biomater. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D4BM00234B, Paper
Open Access
Gaëlle Savin, Sylvain Caillol, Audrey Bethry, Eric Rondet, Michel Assor, Ghislain David, Benjamin Nottelet
Focusing on the regeneration of damaged knee meniscus, we propose a hybrid scaffold made of a poly(ester-urethane) (PEU) and collagen that combines suitable mechanical properties and degradability with enhanced biological...
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Type I and Type II Chemical Biology Toolbox to Overcome the Hypoxic Tumour Microenvironment for Photodynamic Therapy

Biomater. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D4BM00319E, Review Article
Minzi Ju, Lu Yang, Guowei Wang, Feng Zong, Yu Shen, Shuangshuang Wu, Xuna Tang, Decai Yu
Photodynamic therapy (PDT) is a minimally invasive therapeutic modality employed for the treatment of various types of cancers, localized infections, and other diseases. Upon illumination, the photo-excited photosensitizer generates singlet...
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A thermally reversible injectable adhesive for intestine tissue repair and anti-postoperative adhesion

Biomater. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D4BM00164H, Paper
Wenmo Zhang, Runze Zhang, Rong Yang, Yage Sun, Qian Zhang, Xuequan Feng, Chunyan Cui, Wenguang Liu
Intestine damage is an acute abdominal disease that usually requires emergency sealing. However, traditional surgical suture not only causes secondary damage to the injured tissue, but also results in adhesion...
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Applications of hydrogels in tissue-engineered repairing of temporomandibular joint diseases

Biomater. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D3BM01687K, Review Article
Xuan Wang, Fushuang Liu, Tianyi Wang, Yikai He, Yongwen Guo
Epidemiological studies reveal that symptoms of TMD occur in 60-70% of adults. The inflammatory damage caused by TMD can easily lead to defects in the articular disc, condylar cartilage, subchondral...
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Bioactive microgel-coated electrospun membrane with cell-instructive interfaces and topology for abdominal wall defect repair

Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM00182F, Paper
Renquan Xing, Rui Gao, Yini Huangfu, Yufeng Zhang, Shuangyang Li, Chuangnian Zhang, Pingsheng Huang, Weiwei Wang, Anjie Dong, Zujian Feng
A promising bioactive microgel-coated electrospun membrane with cell-instructive interfaces and topology for abdominal wall defect repair.
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css-tricks.com and FOUC on latest Firefox

Hi guys. I am experiencing FOUC when visiting css-tricks.com on latest Firefox Developer Edition. Do you have the same problem?

Here is the video demo video




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RSS Meets the Needs of Direct Marketers

Contrary to general opinion, RSS meets the needs of even the most demanding direct marketer, actually providing most of what e-mail marketing does, except for the strong push factor.

Most direct marketing reasons against RSS are in fact the result of inadequate understanding of RSS by most marketers.

a] Scheduled and autoresponder messages
There are already a few services and software packages on the market that allow for scheduled and autoresponder messages via RSS feeds. Once your visitor subscribes to your special RSS feed, he can receive a pre-determined set of messages in a specific time frame, determined by you. Use these messages to welcome your new reader to your RSS feed; thank your new customer after the purchase, send him additional information about the ordered product and give him the opportunity to buy an additional product at a lower price tag a couple of days later, and so on.

Complete Article - RSS Meets the Needs of Direct Marketers




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The Full Circle of RSS Marketing Power

RSS is a many-in-one marketing & publishing tool, although unfortunatelly most marketers still fail to understand this powerful concept.

While RSS does provide a number of benefits when used for each individual marketing function, best results are achieved when it is fully integrated in your internet marketing strategy. In more simpler terms --- when you use it to power most of your marketing online.

The key point is that RSS makes various marketing functions work together, in order to generate the best possible end result.

Complete Article - The Full Circle RSS Marketing




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Understanding Fair Use and RSS

Keep in mind that fair use is based on the belief that the general public and media are entitled to freely use portions of copyrighted materials. The fair use extends to commentary on the creative works, criticism of creative works, or even the creation of a parody that relates to the copyrighted material. Understanding the intent of the copyright laws help publishers interpret them.

What is Fair Use?




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POCO X6 Pro review: Performance prowess and a smudge of quirks 

The POCO X6 Pro delivers on multiple fronts which include great performance, a nice display and decent battery life. It makes for an interesting value-for-money choice for those looking for a gaming-forward device




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Vivo X100 Pro review: Capturing bison and bonfires, with the first flagship launched in 2024

The smartphone with its 225 grams isn’t exactly lightweight, but it looks classy with its trademark graphite glass finish rear panel




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OnePlus 12 review - First Impressions 

One of the first flagships of the year, what about the OnePlus 12 really stands out? 




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Fit for health, flickering in flair - Honor Choice watch review

The smartwatch offers vivid display, health tracking features, and decent battery life, but suffers from glitchy app




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Small wonder, big on power! MacBook Air with M3 review

Powerful, portable, and long-lasting battery, perfect for productivity on the go




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Bringing in that flagship flair! Samsung Galaxy S24+ review

Does this flagship have what it takes to charm its way into our hearts?




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Twist & shout! Lenovo Auto Twist AI PC - Exclusive first glance

A concept device that shifts shape, and listens to every command you say




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Five careers in the environment sector

For those who want to make the world a better place to live in, here are some options in the environment sector




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The pandemic years to impact hiring in 2023

With job seekers having recalibrated the “instruments” for evaluating organisations, employers have to revisit their hiring strategies in the new year 




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An interview with Dhuwarakha Sriram of YuWaah

As society and workplaces transform, the skills required of youngsters must also evolve, says the Chief of Generation Unlimited (YuWaah), Adolescent/Youth Development and Partnerships at UNICEF India




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‘The question of building stakeholder trust can have more airtime in the boardroom’




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Centre to recruit private sector specialists as joint secretaries, directors and deputy secretaries

The number of vacancies, to be filled through this lateral recruitment, will be advertised on May 20.




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Career counselling, a focal point for students aspiring to join professional courses




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Railways MoU with Airbus to create 15,000 job opportunities for Indian students




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Are resumes losing their relevance? 




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‘Corporates need to make their DE&I narratives more detailed’ 

A new study reveals that only 30% of the companies share the outcomes of the initiatives they have taken to create a level playing field for the various groups that constitute their workforce