da Complicit: On India and the U.S and Canada cases By www.thehindu.com Published On :: Mon, 21 Oct 2024 00:30:00 +0530 India must come clean on its stance on transnational killings Full Article Editorial
da Allow for deliberation: On the legitimate demands of Ladakh By www.thehindu.com Published On :: Tue, 22 Oct 2024 00:15:00 +0530 The lack of a legislature and regional autonomy in Ladakh has led to the current protests Full Article Editorial
da What Makes <I>Andaz Apna Apna</I> Such Fun Even Today By www.rediff.com Published On :: Andaz Apna Apna is practically the most quoted film since Sholay, observes Sukanya Verma, as she celebrates 30 years of this cult classic movie. Full Article
da Alia-Ranbir's Daughter Raha Turns 2 By www.rediff.com Published On :: Alia Bhatt and Ranbir Kapoor's little girl Raha turned two on November 6, and we were treated to the most adorable pictures on social media. Full Article
da Why Abhishek Missed Aishwarya's Birthday By www.rediff.com Published On :: When Aishwarya celebrated her birthday in Dubai on November 1, the speculation regarding the Abhishek-Aishwarya marital rift ran even higher. Full Article
da Design, synthesis, inhibitory activity, and molecular simulations study for D-glucose-conjugated thioureas containing pyrimidine ring as multitarget inhibitors against α-amylase, α-glucosidase, DDP-4, and PTP1B in Type 2 diabetes mellitus By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3395-3417DOI: 10.1039/D4MD00334A, Research ArticleVu Ngoc Toan, Do Son Hai, Hoang Thi Kim Van, Nguyen Minh Tri, Duong Ngoc Toan, Nguyen Thi Thanh Mai, Nguyen Dinh ThanhD-Glucose-conjugated thioureas from 2-aminopyrimidines had inhibitory activity against α-amylase, α-glucosidase, DPP-4, PTP1B. The cytotoxicity, inhibitory kinetics, and molecular simulations of the most potent inhibitors 8k, 8j, 8f, and 8h were studied.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
da Pyridazinone-based derivatives as anticancer agents endowed with anti-microbial activity: molecular design, synthesis, and biological investigation By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3529-3557DOI: 10.1039/D4MD00481G, Research ArticleMohamed K. S. El-Nagar, Mai I. Shahin, Mohammed F. El-Behairy, Ehab S. Taher, Mohamed F. El-Badawy, Marwa Sharaky, Dalal A. Abou El Ella, Khaled A. M. Abouzid, Mai AdelDiscovery of novel pyridazinone derivatives with dual antimicrobial and anticancer activities.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
da Exploring 7β-amino-6-nitrocholestens as COVID-19 antivirals: in silico, synthesis, evaluation, and integration of artificial intelligence (AI) in drug design: assessing the cytotoxicity and antioxidant activity of 3β-acetoxynitrocholestane By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00257A, Research Article Shahabuddin, Uzma, Mohammad Azam, Mehtab Parveen, Nurul Huda Abd Kadir, Kim Min, Mahboob AlamIn light of the ongoing pandemic caused by SARS-CoV-2, effective and clinically translatable treatments are desperately needed for COVID-19 and its emerging variants.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
da Inhibition of monoamine oxidases by heterocyclic derived conjugated dienones: synthesis and in vitro and in silico investigations By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00608A, Research ArticleSunil Kumar, Bishnu Prasad Pandey, Mohamed A. Abdelgawad, Mohammed M. Ghoneim, Rania B. Bakr, Hoon Kim, Bijo MathewA total of 18 heterocyclic derived conjugated dienones (CD1–CD18) were evaluated for their potential monoamine oxidase (MAO)-A/-B inhibitory activity.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
da Synthesis and biological evaluation of novel D-ring fused steroidal N(2)-substituted-1,2,3-triazoles By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00297K, Research ArticleBranislava Tenjović, Sofija Bekić, Andjelka Ćelić, Edward Petri, Julia Scholda, Florian Kopp, Marija Sakač, Andrea NikolićIn this study, a series of 13 new D-ring fused steroidal N(2)-substituted-1,2,3-triazoles were synthesized, characterized and evaluated for their biological activities.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
da Breaking boundaries in diabetic nephropathy treatment: design and synthesis of novel steroidal SGLT2 inhibitors By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00645C, Research ArticleGeetmani Singh Nongthombam, Semim Akhtar Ahmed, Kangkon Saikia, Sanjib Gogoi, Jagat Chandra BorahVirtual screening and synthetic modification of natural product-derived steroidal precursors as potential SGLT2 inhibitors for the treatment of diabetic nephropathy.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
da A decade of pyridine-containing heterocycles in US FDA approved drugs: a medicinal chemistry-based analysis By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00632A, Review ArticleAshish Ranjan Dwivedi, Shivani Jaiswal, Deepak Kukkar, Roshan Kumar, Thakur Gurjeet Singh, Mahendra Pratap Singh, Abhay M. Gaidhane, Sorabh Lakhanpal, K. Nagendra Prasad, Bhupinder KumarThe present review is a concerted effort to cover drugs bearing pyridine rings approved in the last decade, and it provides thorough discussion and commentary on their pharmacokinetics and pharmacodynamics together with in-depth structural analysis.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
da Generation and capture of naphthoquinonynes: a new frontier in the development of trypanocidal quinones via aryne chemistry By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00558A, Research ArticleLaura P. R. Figueroa, Renato L. de Carvalho, Renata G. Almeida, Esther R. S. Paz, Emilay B. T. Diogo, Maria H. Araujo, Warley S. Borges, Victor F. S. Ramos, Rubem F. S. Menna-Barreto, James M. Wood, John F. Bower, Eufrânio N. da Silva JúniorThis article presents A-ring functionalized quinones via a modern and efficient new strategy involving the generation and capture of benzyne quinones and their evaluation against Trypanosoma cruzi.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
da Water level in Mettur Dam stands at 107.04 feet By www.thehindu.com Published On :: Tue, 05 Nov 2024 16:35:38 +0530 Full Article Tiruchirapalli
da Data crucial for building climate resilience, says ISRO scientist By www.thehindu.com Published On :: Tue, 05 Nov 2024 19:40:51 +0530 Full Article Tiruchirapalli
da Water level in Mettur dam stands at 106.89 feet By www.thehindu.com Published On :: Wed, 06 Nov 2024 18:06:24 +0530 Full Article Tiruchirapalli
da Tiruchi Today (November 7, 2024) By www.thehindu.com Published On :: Wed, 06 Nov 2024 18:16:44 +0530 Full Article Tiruchirapalli
da TNSTC Kumbakonam Division mops up ₹17.13 crore in four days By www.thehindu.com Published On :: Wed, 06 Nov 2024 18:59:26 +0530 Full Article Tiruchirapalli
da Pumping stations to be set up in eight low-lying areas in Tiruchi to prevent inundation By www.thehindu.com Published On :: Wed, 06 Nov 2024 19:30:58 +0530 Full Article Tiruchirapalli
da Govt. urged to extend last date to pay crop insurance premium by farmers By www.thehindu.com Published On :: Thu, 07 Nov 2024 17:45:02 +0530 Full Article Tiruchirapalli
da Farmers demand withdrawal of Tamil Nadu Land Consolidation Act By www.thehindu.com Published On :: Thu, 07 Nov 2024 17:59:18 +0530 The Coordination Committee of All Farmers’ Associations of Tamil Nadu says the State government has created a situation where industries can acquire fertile lands Full Article Tiruchirapalli
da Udhayanidhi lays foundation stone for infrastructure development projects in Thanjavur district By www.thehindu.com Published On :: Thu, 07 Nov 2024 18:48:04 +0530 Buildings at the Government Arts and Science College, Thirukkattupalli, construction of compound wall and an indoor stadium at the Government Rajah Serfoji College, Thanjavur, are among the projects Full Article Tiruchirapalli
da Man attempts to end life, kills his wife and daughter By www.thehindu.com Published On :: Sat, 09 Nov 2024 18:03:18 +0530 Full Article Tiruchirapalli
da Water level in Mettur Dam stands at 106.58 feet By www.thehindu.com Published On :: Sat, 09 Nov 2024 18:10:37 +0530 Full Article Tiruchirapalli
da 546: Ryan Dahl and Deno By shoptalkshow.com Published On :: Mon, 19 Dec 2022 09:11:01 +0000 Ryan Dahl stops by to talk about Node, Deno, JavaScript, testing, V8, and thoughts around getting started with Deno. Full Article All Episodes Deno Javascript node
da 550: Sanity with Simen Svale Skogsrud and Espen Hovlandsdal By shoptalkshow.com Published On :: Mon, 30 Jan 2023 10:11:40 +0000 Simen and Espen from Sanity stop by to talk about the origins of Sanity, how Sanity Studio works, good use cases for Sanity, how Sanity does real time updates, what Groq is, and where to start with Sanity. Full Article All Episodes CMS data sanity
da 561: Web Perf News, Web Sommelier, Data Analytics, and Passkeys By shoptalkshow.com Published On :: Mon, 17 Apr 2023 08:00:36 +0000 Topics for this one include how do you learn about web performance news? Do you need a web components sommelier? Our thoughts on Syntax going to Sentry, and being able to focus on the things you want to focus on. Passkeys, Arc split screen, and vibe driven development. Full Article All Episodes arc passkey sommelier Web Components
da 563: Getting Pulled by the Algorithm, AI Training Data, and SVG Drawing By shoptalkshow.com Published On :: Mon, 01 May 2023 08:51:30 +0000 There's a special guest on the show who takes aim at the billionaires in web dev, do we know better than the algorithm for news, why is AI training data such a secret, Chris and Dave discover JetBrains, monorepo struggles, and SVG drawing tools. Full Article All Episodes AI JetBrains PHP
da 570: Haircut Maintenance, Dave’s Bookshelf, Lazy Loading, and APIs By shoptalkshow.com Published On :: Mon, 19 Jun 2023 08:00:42 +0000 We're talking Dave's new haircut, playing Hondo, what Dave uses for images on his bookshelf page, lazy-loading thoughts, vh vw follow up, eyeball tracking updates, loading website with js, Vue transitions, charging for API access, and do you cross post, one post, or no post on social media in 2023? Full Article All Episodes api lazyloading transition
da 578: Customer Support, P3 Color, Dave on Productivity, and Mobile vs Desktop By shoptalkshow.com Published On :: Mon, 14 Aug 2023 07:24:25 +0000 Is Apple's Numbers amazing or the worst? Customer support at various levels of software, Figma and P3 color, imagining a colorspace property in CSS, what's Dave doing for productivity, how has offloading CSS Tricks affected Chris, and should we build different websites for mobile vs desktop? Full Article All Episodes css tricks p3 Productivity Tools
da 579: One Day Builds, Spicy Slugs, and What Next for CSS? By shoptalkshow.com Published On :: Mon, 21 Aug 2023 20:00:21 +0000 Have you ever been an auctioneer? Sometimes when God closes a shed, he opens a sauna. Dave's working on the one day build theory, how to market with fake data, an update on the Discord, marketing with a spicy slug, what we want to see next in CSS, and thoughts on component libraries. Full Article All Episodes CSS marketing slug
da 607: Astro Launches an Integrated Database By shoptalkshow.com Published On :: Mon, 18 Mar 2024 08:39:41 +0000 Fred K. Schott stops by to talk about Astro announcement of Astro DB, the pluses and minuses of it, whether you have to always use the database with Astro DB, how to migrate data, seeding your database, upgrading the database, and what about Astro DB pricing? Full Article All Episodes Astro astro db database
da 614: CSS Grid Level 3 aka Masonry with Adam Argyle By shoptalkshow.com Published On :: Mon, 06 May 2024 08:00:02 +0000 Adam Argyle stops by to chat about the conversation that's happening around CSS Grid / Masonry. What do we want? What might Apple's response to Google be? And nitpicking the spec just for fun. Full Article All Episodes CSS css grid masonry
da 615: Dave Goes Windows For Real By shoptalkshow.com Published On :: Mon, 13 May 2024 22:33:10 +0000 Dave's got job news to share, as well as insight into the process of what applying for a job in tech is like in 2024. We also talk about styling, scoping, positioning, and floating UI. Full Article All Episodes applying for a job employment microsoft windows
da 622: Website Rendering, Updating Software, and Edge Gets Faster By shoptalkshow.com Published On :: Mon, 01 Jul 2024 08:26:04 +0000 We're talking website rendering, server side rendering, Astro's server islands, perf hits for navigation elements, updating software because the docs aren't available for older versions, and a new Microsoft Edge was released. Full Article All Episodes microsoft edge rendering server islands
da 631: Dave’s Second Brain Idea, Notion Thoughts, and Google’s LLM in Chrome By shoptalkshow.com Published On :: Mon, 02 Sep 2024 08:01:07 +0000 Dave's got an idea for a second brain app that's customized to his brain, where we're at with Notion and other notes apps, and accessibility on LLM's in browsers. Full Article All Episodes Chrome LLM notion second brain
da 632: Adam Coster on Game Development and Crashlands 2 By shoptalkshow.com Published On :: Mon, 09 Sep 2024 08:00:41 +0000 Adam Coster talks with us about working with his family in game development, how they get started making games, what all is involved with publishing games, deciding to go Steam and Netflix only for Crashlands 2, how web tech is involved in game development, and the fun of testing and doing Q&A for games. Full Article All Episodes Apple Arcade Development netflix Publishing steam video games
da 639: DX, JSON, XML, HTML, and Databases! Oh My! By shoptalkshow.com Published On :: Mon, 28 Oct 2024 08:49:04 +0000 How important is the DX of software vs how important is the person showing off the software, Douglas Crockford and JSON, remembering XML, trying to write better HTML for email, new TC39 proposal, workshopping t-shirts, and what do you do if you want a little bit of database on your website? Full Article All Episodes database dx Javascript
da Sunny days are here again By www.thehindu.com Published On :: Fri, 02 Jan 2015 16:22:45 +0530 Despite the cost, a solar energy system is a great energy saver and a boon during power cuts, says Anamika Mukherjee Full Article Green Living
da Alternatives and affordability By www.thehindu.com Published On :: Fri, 04 Sep 2015 16:56:02 +0530 Each housing project has to be site-specific, culturally appropriate and climatically conforming. Full Article Property Plus
da Idukki project leapfrogs ‘endangered’ list By www.thehindubusinessline.com Published On :: Sun, 13 Oct 2024 20:06:56 +0530 Local enthusiasts pitch in to bring amphibian species back from the brink of extinction Full Article Clean Tech
da Morning runs, protein-packed breakfast, and a rest day By www.thehindubusinessline.com Published On :: Sun, 20 Oct 2024 20:19:00 +0530 The daily quest to balance work, health, and personal life Full Article Pulse
da How Ratan Tata pushed for evidence-led ayurveda By www.thehindubusinessline.com Published On :: Sun, 20 Oct 2024 20:38:00 +0530 Ratan Tata sought to promote research that could validate ayurveda through contemporary science Full Article Pulse
da Jamiat cautions NDA partners, says ‘crutches’ cannot escape responsibility for Waqf Bill By www.thehindu.com Published On :: Mon, 04 Nov 2024 21:07:19 +0530 The Jamiat Ulama-i-Hind urged NDA partners TDP and JD(U) to heed Muslim sentiments on the contentious issue surrounding the Waqf (Amendment) Bill, 2024 Full Article India
da Govt., BJP spar over Chhath planning as festivities begin today By www.thehindu.com Published On :: Tue, 05 Nov 2024 00:56:12 +0530 Full Article Delhi
da Attempts to douse Alipur warehouse fire continue on second day By www.thehindu.com Published On :: Tue, 05 Nov 2024 01:00:26 +0530 Full Article Delhi
da Delhi govt. to start drive against burning of waste in open today By www.thehindu.com Published On :: Wed, 06 Nov 2024 01:18:55 +0530 Delhi, neighbouring States likely to experience ‘very poor’ quality air over next 10 days, have placed the depts. concerned on high alert: Gopal Rai Full Article Delhi
da Delhi election: AAP to hold nine-day convention for party workers By www.thehindu.com Published On :: Thu, 07 Nov 2024 01:05:04 +0530 Full Article Delhi
da Amit Shah to unveil Birsa Munda statue in Delhi on November 15 By www.thehindu.com Published On :: Thu, 07 Nov 2024 01:06:47 +0530 Full Article Delhi
da Delhi’s air quality remains ‘very poor’, layer of smog over city for ninth day post-Diwali By www.thehindu.com Published On :: Sat, 09 Nov 2024 10:26:29 +0530 Delhi’s air quality reaches severe levels, blamed on stubble-burning, Diwali fireworks, and low wind speed Full Article Delhi