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Linking local microstructure to fracture location in a two-dimensional amorphous solid under isotropic strain

Soft Matter, 2024, Advance Article
DOI: 10.1039/D4SM00486H, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Max Huisman, Axel Huerre, Saikat Saha, John C. Crocker, Valeria Garbin
Machine learning predicts possible crack location in experiments of a fracturing colloid monolayer, shown along with the actual crack path.
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Src kinase slows collective rotation of confined epithelial cell monolayers

Soft Matter, 2024, Accepted Manuscript
DOI: 10.1039/D4SM00827H, Paper
Nastassia Pricoupenko, Flavia Marsigliesi, Philippe Marcq, Carles Blanch-Mercader, Isabelle A Bonnet
Collective cell migration is key during development, wound healing and metastasis and relies on coordinated cell behaviors at the group level. Src kinase is a key signalling protein for physiological...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Enhanced gravitational trapping of bottom-heavy Janus particles over parallel microgrooves

Soft Matter, 2024, Accepted Manuscript
DOI: 10.1039/D4SM00989D, Paper
Yan Wen, Jiayu Liu, Wei Wang, Pik-Yin Lai, Penger Tong
We report a systematic study of barrier-crossing dynamics of bottom-heavy self-propelled particles (SPPs) over a one-dimensional periodic potential landscape $U_0(x)$, which is fabricated on a microgroove-patterned polydimethylsiloxane (PDMS) substrate. From...
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Banana DNA derivatives as homeotropic alignment layers in optical devices

Soft Matter, 2024, 20,8561-8569
DOI: 10.1039/D4SM00322E, Paper
Rafał Węgłowski, Anna Spadło, Dorota Węgłowska
In this study, DNA extracted from bananas was functionalized and used as a homeotropic alignment layer for liquid crystals.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Enhanced chemotaxis efficiency of Escherichia coli in viscoelastic solutions

Soft Matter, 2024, 20,8675-8683
DOI: 10.1039/D4SM01094A, Paper
Shaoying Zhu, Rui He, Caijuan Yue, Rongjing Zhang, Junhua Yuan
E. coli shows enhanced chemotaxis in viscoelastic media, with faster migration and higher accumulation in attractant-rich areas compared to Newtonian conditions.
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Dynamics of switching processes: general results and applications to intermittent active motion

Soft Matter, 2024, Accepted Manuscript
DOI: 10.1039/D4SM01054J, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Ion Santra, Deepak Gupta, Kristian S Olsen
Systems switching between different dynamical phases is an ubiquitous phenomenon. The general understanding of such a process is limited. To this end, we present a general expression that captures fluctuations...
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Fibrotaxis: gradient-free, spontaneous and controllable droplet motion on soft solids

Soft Matter, 2024, Accepted Manuscript
DOI: 10.1039/D4SM01022A, Paper
Open Access
Sthavishtha Bhopalam, Jesus Bueno, Hector Gomez
Most passive droplet transport strategies rely on spatial variations of material properties to drive droplet motion, leading to gradient-based mechanisms with intrinsic length scales that limit the droplet velocity or...
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Biomimetic mineralization of positively charged silica nanoparticles templated by thermoresponsive protein micelles: applications to electrostatic assembly of hierarchical and composite superstructures

Soft Matter, 2024, Advance Article
DOI: 10.1039/D4SM00907J, Paper
Nada Y. Naser, William C. Wixson, Helen Larson, Brandi M. Cossairt, Lilo D. Pozzo, François Baneyx
Exploiting the ability of a solid-binding elastin-like peptide to micellize, we mineralize monodisperse silica nanoparticles whose positive surface charge enables one-step electrostatic assembly of various mono- and bi-material superstructures.
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Individual Closed-Loop Control of Micromotors by Selective Light Actuation

Soft Matter, 2024, Accepted Manuscript
DOI: 10.1039/D4SM00810C, Communication
Open Access
David Rivas, Max Sokolich, Sambeeta Das
Control of individual micromotors within a group would allow for improved efficiency, greater ability to accomplish complex tasks, higher throughput, and increased adaptability. However, independent control of micromotors remains a...
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The influence of active agent motility on SIRS epidemiological dynamics

Soft Matter, 2024, Advance Article
DOI: 10.1039/D4SM00864B, Paper
Open Access
R. Kailasham, Aditya S. Khair
Motility induced phase separation of active disks with SIRS epidemiological dynamics.
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Z’s Still Not Dead Baby, Z’s Still Not Dead

Andy Clarke digs deep into snow to find ways flat design can be brought back to life in CSS with the use of techniques to create a sense of depth. Like spring after an everlasting winter, perhaps it’s time to let a different style of design flourish. What a relief.


A reaction to overly ornamental designs, flat design has been the dominant aesthetic for almost a decade. As gradients, patterns, shadows, and three-dimensional skeuomorphism fell out of fashion, designers embraced solid colours, square corners, and sharp edges.

Anti-skeuomorphism no doubt helped designers focus on feature design and usability without the distraction of what some might still see as flourishes. But, reducing both product and website designs to a bare minimum has had unfortunate repercussions. With little to differentiate their designs, products and websites have adopted a regrettable uniformity which makes it difficult to distinguish between them.

Still, all fashions fade eventually. I’m hopeful that with the styling tools we have today, we’ll move beyond flatness and add an extra dimension. Here are five CSS properties which will bring depth and richness to your designs.

To illustrate how you might use them, I’ve made this design for the 1961 Austin Seven 850, the small car which helped define the swinging sixties.

The original Mini. Red, (British Racing) green, blue designs.

Transparency with alpha values

The simplest way to add transparency to a background colour, border, or text element is using alpha values in your colour styles. These values have been available in combination with RGB (red, green, blue) for years. In RGBA, decimal values below 1 make any colour progressively more transparent. 0 is the most transparent, 1 is the most opaque:

body {
  color: rgba(255, 0, 153, .75); 
}
Alpha values allow colour from a background to bleed through.

Alpha values also combine with HSL (hue, saturation, lightness) to form HSLA:

body {
  color: hsla(0, 0, 100, .75);
}

Currently a Working Draft, CSS Color Module Level 4 enables alpha values in RGB and HSL without the additional “A”:

body {
  color: rgb(255, 0, 153, .75);
  /* color: hsl(0, 0, 100, .75); */
}

This new module also introduces hexadecimal colours with alpha values. In this new value, the last two digits represent the transparency level, with FF producing 100% opacity and 00 resulting in 100% transparency. For the 75% opacity in my design, I add BF to my white hexadecimal colour:

body {
  color: #ffffffbf;
}

Although there’s already wide support for hexadecimal, HSL, and RGB with alpha values in most modern browsers, the current version of Microsoft Edge for Windows has lagged behind. This situation will no doubt change when Microsoft move Edge to Chromium.

2. Use opacity

Using the opacity property specifies the amount of opacity of any element (obviously) which allows elements below them in the stacking order to be all or partially visible. A value of 0 is most transparent, whereas 1 is most opaque.

Opacity tints images with colour from elements behind them.

This property is especially useful for tinting the colour of elements by allowing any colour behind them to bleed through. The British Motor Corporation logo in the footer of my design is solid white, but reducing its opacity allows it to take on the colour of the body element behind:

[src*="footer"] {
  opacity: .75; 
}

You might otherwise choose to use opacity values as part of a CSS filter. 0% opacity is fully transparent, while 100% is fully opaque and appears as if no filter has been applied. Applying a CSS filter is straightforward. First, declare the filter-function and then a value in parentheses:

[src*="footer"] {
  filter: opacity(75%); 
}

3. Start blending

Almost universally, contemporary browsers support the same compositing tools we’ve used in graphic design and photo editing software for years. Blend modes including luminosity, multiply, overlay, and screen can easily and quickly add depth to a design. There are two types of blend-mode.

background-blend-mode defines how background layers blend with the background colour behind them, and with each other. My layered design requires three background images applied to the body element:

body {
  padding: 2rem;
  background-color: #ba0e37;
  background-image:
    url(body-1.png),
    url(body-2.png),
    url(body-3.png);
  background-origin: content-box;
  background-position: 0 0;
  background-repeat: no-repeat;
  background-size: contain;
}
From left: Three background images. Far right: How images combine in a browser.

You can apply different background-blend modes for each background image. Specify them in the same order as your background images and separate them with a comma:

body {
  background-blend-mode: multiply, soft-light, hard-light;
}
Six background-blend-mode variations.

When I need to apply an alternative colour palette, there’s no need to export new background assets. I can achieve results simply by changing the background colour and these background-blend modes.

Backgrounds blend behind this brilliant little car.

Sadly, there’s not yet support for blending modes in Edge, so provide an alternative background image for that browser:

@supports not (background-blend-mode: normal) {
  body {
    background-image: url(ihatetimvandamme.png); 
  }
}

mix-blend-mode, on the other hand, defines how an element’s content should blend with its ancestors.

From left: Screen, overlay, and soft-light mix-blend-mode.

To blend my Mini image with the background colours and images on the body, I add a value of hard-light, plus a filter which converts my full-colour picture to greyscale:

[src*="figure"] {
  filter: grayscale(100%);
  mix-blend-mode: hard-light; 
}

You can also use mix-blend-mode to add depth to text elements, like this headline and large footer paragraph in a green and yellow version of my design:

.theme-green h1,
.theme-green footer p:last-of-type {
  color: #f8Ef1c;
  mix-blend-mode: difference;
}
Text elements blend to add interest in my design.

4. Overlap with CSS Grid

Whereas old-fashioned layout methods reinforced a rigid structure on website designs, CSS Grid opens up the possibility to layer elements without positioning or resorting to margin hacks. The HTML for my design is semantic and simple:

<body>

<p>You’ve never seen a car like it</p>

<h1><em>1961:</em> small car of the year</h1>

<figure>
  <img src="figure.png" alt="Austin Seven 850">
  <figcaption>
    <ul>
      <li>Austin Super Seven</li>
      <li>Morris Super Mini-Minor</li>
      <li>Austin Seven Cooper</li>
      <li>Morris Mini-Cooper</li>
    </ul>
  <figcaption>
</figure>

<footer>
  <p>Today’s car is a Mini</p>
  <p>Austin Seven 850</p>
  <img src="footer.png" alt="Austin Seven 850">
<footer>

</body>

I begin by applying a three-column symmetrical grid to the body element:

@media screen and (min-width : 48em) {

  body {
    display: grid;
    grid-template-columns: 1fr 1fr 1fr; 
  }

}
Three-column symmetrical grid with column and row lines over my design.

Then, I place my elements onto that grid using line numbers:

body > p {
  grid-column: 1 / -1; 
}

h1 {
  grid-column: 1 / 3; 
}

figure {
  grid-column: 1 / -1; 
}

footer {
  display: contents; 
}

footer div {
  grid-column: 1 / 3; 
}  

[src*="footer"] {
  grid-column: 3 / -1;
  align-self: end; 
}

As sub-grid has yet to see wide adoption, I apply a second grid to my figure element, so I may place my image and figcaption:

figure {
  display: grid;
  grid-template-columns: 1fr 3fr; 
}

figcaption {
  grid-column: 1; 
}

[src*="figure"] {
  grid-column: 2; 
}
Left: This conventional alignment lacks energy. Right: Overlapping content adds movement which makes my design more interesting overall.

Previewing the result in a browser shows me the energy associated with driving this little car is missing. To add movement to my design, I change the image’s grid-column values so it occupies the same space as my caption:

figcaption {
  grid-column: 1;
  grid-row: 3; 
}

[src*="figure"] {
  grid-column: 1 / -1; 
  grid-row: 3;
  padding-left: 5vw; 
}

5. Stack with z-index

In geometry, the x axis represents horizontal, the y axis represents vertical. In CSS, the z axis represents depth. Z-index values can be either negative or positive and the element with the highest value appears closest to a viewer, regardless of its position in the flow. If you give more than one element the same z-index value, the one which comes last in source order will appear on top.

Visualisation of z-index illustrates the depth in this design.

It’s important to remember that z-index is only applied to elements which have their position property set to either relative or absolute. Without positioning, there is no stacking. However, z-index can be used on elements placed onto a grid.

All techniques combined to form a design which has richness and depth.

As the previous figure image and figcaption occupy the same grid columns and row, I apply a higher z-index value to my caption to bring it closer to the viewer, despite it appearing before the picture in the flow of my content:

figcaption {
  grid-column: 1;
  grid-row: 3;
  z-index: 2; 
}

[src*="figure"] {
  grid-column: 1 / -1; 
  grid-row: 3;
  z-index: 1; 
}

Z’s not dead baby, Z’s not dead

While I’m not advocating a return to the worst excesses of skeuomorphism, I hope product and website designers will realise the value of a more vibrant approach to design; one which appreciates how design can distinguish a brand from its competition.


I’m incredibly grateful to Drew and his team of volunteers for inviting me to write for this incredible publication every year for the past fifteen years. As I closed my first article here on this day all those years ago, “Have a great holiday season!” Z’s still not dead baby, Z’s still not dead.


About the author

Andy Clarke is one of the world’s best-known website designers, consultant, speaker, and writer on art direction and design for products and websites. Andy founded Stuff & Nonsense in 1998 and for 20 years has helped companies big and small to improve their website and product designs. Andy’s the author of four web design books including ‘Transcending CSS,’ ‘Hardboiled Web Design’ and ‘Art Direction for the Web’. He really, really loves gorillas.

More articles by Andy




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Four Ways Design Systems Can Promote Accessibility – and What They Can’t Do

Amy Hupe prepares a four bird roast of tasty treats so we can learn how the needs of many different types of users can be served through careful implementation of components within a design system.


Design systems help us to make our products consistent, and to make sure we’re creating them in the most efficient way possible. They also help us to ensure our products are designed and built to a high quality; that they’re not only consistent in appearance, and efficiently-built, but that they are good. And good design means accessible design.

1 in 5 people in the UK have a long term illness, impairment or disability – and many more have a temporary disability. Designing accessible services is incredibly important from an ethical, reputational and commercial standpoint. For EU government websites and apps, accessibility is also a legal requirement.

With that in mind, I’ll explain the four main ways I think we can use design systems to promote accessible design within an organisation, and what design systems can’t do.

1. Bake it in

Design systems typically provide guidance and examples to aid the design process, showing what best practice looks like. Many design systems also encompass code that teams can use to take these elements into production. This gives us an opportunity to build good design into the foundations of our products, not just in terms of how they look, but also how they work. For everyone.

Let me give an example.

The GOV.UK Design System contains a component called the Summary list. It’s used in a few different contexts on GOV.UK, to summarise information. It’s often used at the end of a long or complex form, to let users check their answers before they send them, like this:

Users can review the information and, if they’ve entered something incorrectly, they can go back and edit their answer by clicking the “Change” link on the right-hand side. This works well if you can see the change link, because you can see which information it corresponds to.

In the top row, for example, I can see that the link is giving me the option to change the name I’ve entered because I can see the name label, and the name I put in is next to it.

However, if you’re using a screen reader, this link – and all the others – will just say “change”, and it becomes harder to tell what you’re selecting. So to help with this, the GOV.UK Design System team added some visually-hidden text to the code in the example, to make the link more descriptive.

Sighted users won’t see this text, but when a screen reader reads out the link, it’ll say “change name”. This makes the component more accessible, and helps it to satisfy a Web Content Accessibility Guidelines (WCAG 2.1) success criterion for links which says we must “provide link text that identifies the purpose of the link without needing additional context”.

By building our components with inclusion in mind, we can make it easier to make products accessible, before anyone’s even had to think about it. And that’s a great starting point. But that doesn’t mean we don’t have to think about it – we definitely do. And a design system can help with that too.

2. Explain it

Having worked as the GOV.UK Design System’s content designer for the best part of 3 years, I’m somewhat biased about this, but I think that the most valuable aspect of a design system is its documentation.

(Here’s a shameless plug for my patterns Day talk on design system documentation earlier this year, if you want to know more about that.)

When it comes to accessibility, written documentation lets us guide good practice in a way that code and examples alone can’t.

By carefully documenting implementation rules for each component, we have an opportunity to distribute accessible design principles throughout a design system. This means design system users encounter them not just once, but repeatedly and frequently, in various contexts, which helps to build awareness over time.

For instance, WCAG 2.1 warns against using colour as “the only visual means of conveying information, calling an action, prompting a response or distinguishing a visual element”. This is a general principle to follow, but design system documentation lets us explain how this relates to specific components.

Take the GOV.UK Design System’s warning buttons. These are used for actions with serious, often destructive consequences that can’t easily be undone – like permanently deleting an account.

The example doesn’t tell you this, but the guidance explains that you shouldn’t rely on the red colour of warning buttons to communicate that the button performs a serious action, since not all users will be able to see the colour or understand what it signifies.

Instead, it says, “make sure the context and button text makes clear what will happen if the user selects it”. In this way, the colour is used as an enhancement for people who can interpret it, but it’s not necessary in order to understand it.

Making the code in our examples and component packages as accessible as possible by default is really important, but written documentation like this lets us be much more explicit about how to design accessible services.

3. Lead by example

In our design systems’ documentation, we’re telling people what good design looks like, so it’s really important that we practice what we preach.

Design systems are usually for members of staff, rather than members of the public. But if we want to build an inclusive workplace, we need to hold them to the same standards and ensure they’re accessible to everyone who might need to use them – today and in the future.

One of the ways we did this in my team, was by making sure the GOV.UK Design System supports users who need to customise the colours they use to browse the web. There are a range of different user needs for changing colours on the web. People who are sensitive to light, for instance, might find a white background too bright. And some users with dyslexia find certain colours easier to read than others.

My colleague, Nick Colley, wrote about the work we did to ensure GOV.UK Design System’s components will work when users change colours on GOV.UK. To ensure we weren’t introducing barriers to our colleagues, we also made it possible to customise colours in the GOV.UK Design System website itself.

Building this flexibility into our design system helps to support our colleagues who need it, but it also shows others that we’re committed to inclusion and removing barriers.

4. Teach it

The examples I’ve drawn on here have mostly focused on design system documentation and tooling, but design systems are much bigger than that. In the fortuitously-timed “There is No Design System”, Jina reminds us that tooling is just one of the ways we systematise design:

…it’s a lot of people-focused work: Reviewing. Advising. Organizing. Coordinating. Triaging. Educating. Supporting.”

To make a design system successful, we can’t just build a set of components and hope they work. We have to actively help people find it, use it and contribute to it. That means we have to go out and talk about it. We have to support people in learning to use it and help new teams adopt it. These engagement activities and collaborative processes that sit around it can help to promote awareness of the why, not just the what.

At GDS, we ran workshops on accessibility in the design system, getting people to browse various web pages using visual impairment simulation glasses to understand how visually impaired users might experience our content. By working closely with our systems’ users and contributors like this, we have an opportunity to bring them along on the journey of making something accessible.

We can help them to test out their code and content and understand how they’ll work on different platforms, and how they might need to be adjusted to make sure they’re accessible. We can teach them what accessibility means in practice.

These kinds of activities are invaluable in helping to promote accessible design thinking. And these kinds of lessons – when taught well – are disseminated as colleagues share knowledge with their teams, departments and the wider industry.

What design systems can’t do

Our industry’s excitement about design systems shows no signs of abating, and I’m excited about the opportunities it affords us to make accessible design the default, not an edge case. But I want to finish on a word about their limitations.

While a design system can help to promote awareness of the need to be accessible, and how to design products and services that are, a design system can’t make an organisation fundamentally care about accessibility.

Even with the help of a thoughtfully created design system, it’s still possible to make really inaccessible products if you’re not actively working to remove barriers. I feel lucky to have worked somewhere that prioritises accessibility. Thanks to the work of some really brilliant people, it’s just part of the fabric at GDS. (For more on that work and those brilliant people, I can’t think of a better place to start than my colleague Ollie Byford’s talk on inclusive forms.)

I’m far from being an accessibility expert, but I can write about this because I’ve worked in an organisation where it’s always a central consideration. This shouldn’t be something to feel lucky about. It should be the default, but sadly we’re not there yet. Not even close.

Earlier this year, Domino’s pizza was successfully sued by a blind customer after he was unable to order food on their website or mobile app, despite using screen-reading software. And in a recent study carried out by disability equality charity, Scope, 50% of respondents said that they had given up on buying a product because the website, app or in-store machine had accessibility issues.

Legally, reputationally and most importantly, morally, we all have a duty to do better. To make sure our products and services are accessible to everyone. We can use design systems to help us on that journey, but they’re just one part of our toolkit.

In the end, it’s about committing to the cause – doing the work to make things accessible. Because accessible design is good design.


About the author

Amy is a content specialist and design systems advocate who’s spent the last 3 years working as a Senior Content Designer at the Government Digital Service.

In that time, she’s led the content strategy for the GOV.UK Design System, including a straightforward and inclusive approach to documentation.

In January, Amy will continue her work in this space, in her new role as Product Manager for Babylon Health’s design system, DNA.

More articles by Amy




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Suo motu cases against YSRCP chief Jagan if he issues threats to police officers, warns Andhra Pradesh Deputy CM Pawan

The government is not prepared to take lightly the former Chief Minister’s recent statement that he would not spare some IPS officers even after their retirement, asserts Pawan Kalyan; the government will not let the sacrifices of forest martyrs go waste, he says




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Traditional healers told not to treat infants, children to prevent mortalities in Chintoor agency

The methods and ingredients used in the preparation of Ayurvedic medicine by traditional healers are to be suspected, says an official




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Man arrested and 20 stolen motorcycles worth ₹15 lakh recovered in Nandyal




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Good potential for cosmetic, textile, food processing sectors in Andhra Pradesh: South Korean diplomat

South Koreans are familiar with Andhra Pradesh and since Kia Motors is here, more Korean companies may wish to come too, says Sangwoo Lim




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Anantapur enforcement dirve: police register over 3,000 cases against violators of Motor Vehicle Act

In the drive conducted over one week, police register 12 cases against gambling dens, arrest 59 persons and seize more than ₹1.91 lakh cash, says SP P. Jagadeesh




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In Jammu and Kashmir, it was a vote for strengthening the democratic process

While Statehood seems to be the main ground of convergence, party choices sharply bring to the fore the divergences between the Jammu region and Kashmir Valley



  • Jammu and Kashmir Assembly