mo Study on the affinity sites of cadmium's binding to ligands by thermodynamics and nuclear magnetic resonance spectroscopy By pubs.rsc.org Published On :: Anal. Methods, 2024, Advance ArticleDOI: 10.1039/D3AY02253F, PaperJinsong Yu, Xu Huang, Xiuxiu Wu, Hui Cao, Min Yuan, Tai Ye, Fei XuAccording to the experimental parameters for the interaction of Cd(II) with ligands, the binding sites of Cys and GSH were –SH, –NH2 and –COOH, and the thermodynamic behaviour of Cd(II) with Cys/GSH in boric acid and HEPES buffers was different, exothermic in HEPES but endothermic in boric acid.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mo An efficient electrochemical sensor based on the Ce-MOF/g-C3N5 composite for the detection of nitrofurazone By pubs.rsc.org Published On :: Anal. Methods, 2024, Advance ArticleDOI: 10.1039/D3AY02221H, PaperJianxia Gu, Yiqiong Jia, Zhanbin Jin, Tingting Wei, Yongxia LiThe Ce-MOF/g-C3N5 composite was first constructed using a simple reflux method in an oil bath, and the electrochemical sensor fabricated based on this composite shows excellent detection performance in nitrofurazone detection in practical samples.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mo Dual-mode detection of 2,6-pyridinedicarboxylic acid based on the enhanced peroxidase-like activity and fluorescence property of novel Eu-MOFs By pubs.rsc.org Published On :: Anal. Methods, 2024, Advance ArticleDOI: 10.1039/D4AY00331D, PaperJintao Yi, Xianqin Han, Jiahao Jian, Yayan Lai, Jun Lu, Lei Peng, Zhongkai Liu, Jun Xue, Hui Zhou, Xun LiThe dual-mode fluorescence and colorimetric detection of 2,6-pyridinedicarboxylic acid (DPA) based on the enhanced peroxidase-like activity and fluorescence property of a novel MOF.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mo A Multimode Biosensor Based on Prussian Blue Nanoparticle Loaded with Gold Nanoclusters for the Detection of Aflatoxin B1 By pubs.rsc.org Published On :: Anal. Methods, 2024, Accepted ManuscriptDOI: 10.1039/D3AY02330C, Paperzhaodi Fu, juan Huang, Wei Wei, zhihui Wu, Xingbo ShiHerein, a novel fluorescent/colorimetric/photothermal biosensor is proposed for aflatoxin B1 (AFB1) detection in food based on Prussian blue nanoparticles (PBNPs) (~50 nm), gold nanocluster (AuNCs) and aptamer (Apt) within three...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mo Converging optical and electrochemical detection strategies for multimodal hydrazine sensing: insights into substituent-driven diverse response By pubs.rsc.org Published On :: Anal. Methods, 2024, Advance ArticleDOI: 10.1039/D4AY00063C, PaperRikitha S. Fernandes, Sahil Deepak Vasistha, Ritesh Kumar Singh, Sanket Goel, Nilanjan DeyA pair of pyrene-based chalcogen derivatives have been developed, which demonstrate multimodal ratiometric response towards hydrazine.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mo A novel ratiometric sensor for fluorimetric and visual dual-mode detection of Al3+ in environmental water based on the target-regulated formation of Eu MOFs By pubs.rsc.org Published On :: Anal. Methods, 2024, Advance ArticleDOI: 10.1039/D4AY00324A, PaperTao-Li Chen, Xiang-Juan Kong, Xin-Xin Dong, Zhi-Jie Mao, Fang-Fang Kong, Qiang XiaoThe illustration of the ratiometric sensor for fluorimetric (A) and visual detection (B) of Al3+.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mo Layer-by-layer assembly of homopolypeptide polyelectrolytes on asymmetric nanochannels for the detection of nickel ions By pubs.rsc.org Published On :: Anal. Methods, 2024, Advance ArticleDOI: 10.1039/D4AY00422A, PaperPengrong An, Jincan Yang, Tianming Wang, Saiwen Lu, Dehao Wang, Zhuoyue Wang, Chun-Lin Sun, Chuanguang Qin, Jun LiWe report PA-γ-PGA-modified asymmetric nanochannels that enable ultra-sensitive detection of Ni2+ (limit of detection is 1 × 10−8 M).To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mo LAMP-based hydrogen ion selective electrochemical sensor for highly sensitive detection of Mycoplasma pneumoniae By pubs.rsc.org Published On :: Anal. Methods, 2024, Accepted ManuscriptDOI: 10.1039/D4AY00341A, PaperHuiqing Wang, Yang Li, Lin Tian, Xinyi Li, Qian Gao, Yaru Liu, Cuiping Ma, Qing Wang, Chao ShiAn urgent need for a concise and rapid detection method for Mycoplasma pneumoniae is required due to its severe impact on human’s health. To meet such a need, this study...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mo Rapid detection of monkeypox virus and differentiation of West African and Congo Basin strains using endonuclease restriction-mediated real-time PCR-based testing By pubs.rsc.org Published On :: Anal. Methods, 2024, Advance ArticleDOI: 10.1039/D4AY00492B, PaperJuan Zhou, Fei Xiao, Xiaolan Huang, Jin Fu, Nan Jia, Chunrong Sun, Min Chen, Zheng Xu, Hui Huang, Yi WangA novel multiplex ET-PCR assay that integrates PCR amplification, restriction endonuclease cleavage and real-time fluorescence detection was devised to diagnose MPXV infection and distinguish the Congo Basin and West Africa MPXV strains.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mo Phenylboronic acid modification-based novel dumbbell-shaped Au–Ag nanorod SERS substrates for ultrasensitive detection of SO42− By pubs.rsc.org Published On :: Anal. Methods, 2024, 16,2311-2321DOI: 10.1039/D3AY01831H, PaperKang Shen, Caili Bi, Haifan Yang, Miaowen Xu, Lili Huang, Youwei WangBased on the coordination principle of Lewis acids, a novel 4-MPBA-modified dumbbell-shaped Au–Ag nanorod (4-MPBA@DS Au–AgNR) SERS substrate was developed to realize the high sensitivity and specificity of SO42− detection.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mo Advancements in the development of fluorescent chemosensors based on CN bond isomerization/modulation mechanistic approaches By pubs.rsc.org Published On :: Anal. Methods, 2024, 16,2198-2228DOI: 10.1039/D3AY02321D, Critical ReviewArpna Tamrakar, Manzoor Ahmad Wani, Gargi Mishra, Ankur Srivastava, Rampal Pandey, Mrituanjay D. PandeyThe CN bond isomerization/modulation as a fluorescence signalling mechanism was explored by studying the photophysical properties of conformationally restricted molecules.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mo Polymeric membrane potentiometric sensors based on template-removal-free imprinted receptors for determination of antibiotics By pubs.rsc.org Published On :: Anal. Methods, 2024, Accepted ManuscriptDOI: 10.1039/D4AY00263F, PaperXinyao Wang, Guohua Cui, Rongning Liang, Wei QinCurrently, Nernstian-response-based polymeric membrane potentiometric sensors using the molecularly imprinted polymers (MIPs) as the receptors have been successfully developed for determination of organic ionic species. However, the preparation of these...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mo A chemodosimetric chemosensor for the ratiometric detection of nerve agent-mimic DCP in solution and vapor phases By pubs.rsc.org Published On :: Anal. Methods, 2024, Advance ArticleDOI: 10.1039/D4AY00451E, PaperShilpita Banerjee, Pintu Ghosh, Anirban Karak, Dipanjan Banik, Ajit Kumar MahapatraThe probe MNFZ undergoes a hydrolysis reaction in the presence of DCP to exhibit a naked eye color change from blue to cyan. It was successfully applied to sense DCP in the vapor phase.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mo A highly selective probe engineered to detect polarity and distinguish normal cells and tumor cells in tissue sections By pubs.rsc.org Published On :: Anal. Methods, 2024, Advance ArticleDOI: 10.1039/D4AY00438H, PaperSai Zhu, Lixuan Dai, Xiaoli Zhong, Weiying LinWe have designed a polarity fluorescent probe (DCI-Cou-polar) with high selectivity for diagnosing cancer.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mo Monolith stationary phases prepared via cyclic anhydride ring-opening polymerization as tunable platforms for chromatographic applications By pubs.rsc.org Published On :: Anal. Methods, 2024, Accepted ManuscriptDOI: 10.1039/D4AY00251B, PaperAhmad Aqel, Ayman Ghafr, A. Yacine Badjah-Hadj-Ahmed, Zeid Abdullah ALOthmanPolymer monolithic stationary phases were prepared based on a cyclic anhydride as a reactive and tunable platform via ring-opening post-polymerization using primary amines; octadecylamine and benzylamine. The characterization techniques indicated...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mo Are These the Most Interesting Front-end Developer Tools for 2021? By www.impressivewebs.com Published On :: Tue, 05 Jan 2021 09:47:31 +0000 When I come to the end of any given year, it’s always interesting to look back through the click-through stats for my weekly newsletter Web Tools Weekly to see which tools got the most attention. This year wasn’t all that different from previous years. I’ve learned that clicks happen for basically one of two reasons: The post Are These the Most Interesting Front-end Developer Tools for 2021? appeared first on Impressive Webs. Full Article Roundups and Resources
mo How to Disable JavaScript in Almost Any Browser By www.impressivewebs.com Published On :: Mon, 04 Apr 2022 10:00:00 +0000 In 2022 I think it’s still important as a web developer to test your how your websites look and function when users disable JavaScript in their browser. Developing in this way used to be a cornerstone of Progressive Enhancement and can be handy on both desktop or mobile. I still find myself wanting disabling JavaScript on pages I visit. Sometimes it’s to test a page I’m working on, but in other instances it’s simply to visit a web page that’s not functioning correctly and I want to see if JavaScript is the culprit. The post How to Disable JavaScript in Almost Any Browser appeared first on Impressive Webs. Full Article Browsers JavaScript Web Design Articles Web Design Tutorials
mo Being Mobile By www.thehindubusinessline.com Published On :: Tue, 26 Feb 2013 15:10:54 +0530 Full Article R Dinakaran
mo More 'dead' mobile services? By www.thehindubusinessline.com Published On :: Tue, 19 Mar 2013 16:29:07 +0530 Full Article R Dinakaran
mo How mobile data can help rationalise bus routes By www.thehindubusinessline.com Published On :: Wed, 01 May 2013 16:35:55 +0530 Full Article R Dinakaran
mo The not-so-smart use of mobiles By www.thehindubusinessline.com Published On :: Wed, 07 Aug 2013 17:27:58 +0530 Full Article R Dinakaran
mo Party on the move: On the Aam Aadmi Party, its leader By www.thehindu.com Published On :: Thu, 19 Sep 2024 00:20:00 +0530 AAP’s Arvind Kejriwal continues to surprise, also outlining his political ambitions Full Article Editorial
mo Unwarranted curbs: On the Centre’s move on a ‘fact-checking unit’ By www.thehindu.com Published On :: Mon, 23 Sep 2024 00:20:00 +0530 Fact-checking cannot be an excuse to impose censorship Full Article Editorial
mo Visit wrap-up: On PM Modi’s U.S. visit, announcements By www.thehindu.com Published On :: Wed, 25 Sep 2024 00:20:00 +0530 The Modi U.S. visit announcements will see New Delhi being put to the test Full Article Editorial
mo The other monsoon: On the northeast monsoon By www.thehindu.com Published On :: Sat, 05 Oct 2024 00:08:24 +0530 Better modelling of the impact of northeast monsoon is essential Full Article Editorial
mo Israel versus the UN: On Tel Aviv’s move and India’s response By www.thehindu.com Published On :: Sat, 19 Oct 2024 00:20:00 +0530 India’s stand must keep in mind the UN’s importance in the global order Full Article Editorial
mo Cost of Games: On the 2026 Commonwealth Games By www.thehindu.com Published On :: Fri, 25 Oct 2024 00:10:00 +0530 Taking out popular sports from the CWG is a short-term solution Full Article Editorial
mo Design, synthesis, inhibitory activity, and molecular simulations study for D-glucose-conjugated thioureas containing pyrimidine ring as multitarget inhibitors against α-amylase, α-glucosidase, DDP-4, and PTP1B in Type 2 diabetes mellitus By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3395-3417DOI: 10.1039/D4MD00334A, Research ArticleVu Ngoc Toan, Do Son Hai, Hoang Thi Kim Van, Nguyen Minh Tri, Duong Ngoc Toan, Nguyen Thi Thanh Mai, Nguyen Dinh ThanhD-Glucose-conjugated thioureas from 2-aminopyrimidines had inhibitory activity against α-amylase, α-glucosidase, DPP-4, PTP1B. The cytotoxicity, inhibitory kinetics, and molecular simulations of the most potent inhibitors 8k, 8j, 8f, and 8h were studied.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mo Lead optimisation of OXS007417: in vivo PK profile and hERG liability modulation to optimise a small molecule differentiation agent for the potential treatment of acute myeloid leukaemia By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3495-3506DOI: 10.1039/D4MD00275J, Research Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Thomas J. Cogswell, Laia Josa-Culleré, David Zimmer, Sébastien R. G. Galan, Morgan Jay-Smith, Kate S. Harris, Carole J. R. Bataille, Thomas R. Jackson, Douzi Zhang, Stephen G. Davies, Paresh Vyas, Thomas A. Milne, Graham M. Wynne, Angela J. RussellThe optimisation of a class of AML differentiation agents is described to show improved potency, solubility and stability, reduced off target toxicity, and tumour regression in a murine model in vivo.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mo The synthesis and bioactivities of ROCK2 inhibitors with 1,2-dithiolan-3-yl motif By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3576-3596DOI: 10.1039/D4MD00438H, Research ArticleRuolin Cao, Fangyu Du, Zhiqiang Liu, Pengcheng Cai, Minggang Qi, Wei Xiao, Xuefei Bao, Guoliang ChenRho-associated coiled-coil containing kinase (ROCK) plays an important role in inflammation.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mo Pyridazinone-based derivatives as anticancer agents endowed with anti-microbial activity: molecular design, synthesis, and biological investigation By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3529-3557DOI: 10.1039/D4MD00481G, Research ArticleMohamed K. S. El-Nagar, Mai I. Shahin, Mohammed F. El-Behairy, Ehab S. Taher, Mohamed F. El-Badawy, Marwa Sharaky, Dalal A. Abou El Ella, Khaled A. M. Abouzid, Mai AdelDiscovery of novel pyridazinone derivatives with dual antimicrobial and anticancer activities.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mo Design, synthesis and biological evaluation of a novel PSMA–PI3K small molecule drug conjugate By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3485-3494DOI: 10.1039/D4MD00246F, Research ArticleShouguo Peng, Haixia Li, Weilu Cui, Tianning Xiong, Jiaqi Hu, Haixiang Qi, Songwen Lin, Deyu Wu, Ming Ji, Heng XuA novel PSMA–PI3K small molecule drug conjugate has been prepared, highlighting its potential in targeted cancer therapy.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mo Rationally modified SNX-class Hsp90 inhibitors disrupt extracellular fibronectin assembly without intracellular Hsp90 activity By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3609-3615DOI: 10.1039/D4MD00501E, Research Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Gciniwe S. Mathenjwa, Abir Chakraborty, Abantika Chakraborty, Ronel Muller, Mathew P. Akerman, Moira L. Bode, Adrienne L. Edkins, Clinton G. L. VealeRationally modified Hsp90 inhibitors which retained of on-target activity but showed no engagement of intracellular Hsp90, or stimulation of the heat shock response, were found to significantly alter the extracellular fibronectin network.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mo Sidechain structure–activity relationships of cyclobutane-based small molecule αvβ3 antagonists By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3616-3624DOI: 10.1039/D4MD00306C, Research Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Adam Throup, Manar Saleh Zraikat, Andrew Gordon, Shohreh Jafarinejad Soumehsaraei, Kathrin D. Haase, Laurence H. Patterson, Patricia A. Cooper, Katherine Hanlon, Paul M. Loadman, Mark Sutherland, Steven D. Shnyder, Helen M. SheldrakeCyclobutanes provide a versatile scaffold for the synthesis of small molecule integrin antagonists with good metabolic stability and in vivo tolerability.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mo Inhibition of monoamine oxidases by heterocyclic derived conjugated dienones: synthesis and in vitro and in silico investigations By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00608A, Research ArticleSunil Kumar, Bishnu Prasad Pandey, Mohamed A. Abdelgawad, Mohammed M. Ghoneim, Rania B. Bakr, Hoon Kim, Bijo MathewA total of 18 heterocyclic derived conjugated dienones (CD1–CD18) were evaluated for their potential monoamine oxidase (MAO)-A/-B inhibitory activity.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mo Therapeutic upregulation of DNA repair pathways: strategies and small molecule activators By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00673A, Review ArticleJuhyung Song, Cheoljun Park, Francis E. B. Cabanting, Yong Woong JunPotential therapeutic target proteins for upregulating DNA repair system are reviewed, along with reported small-molecule activators.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mo Modulating polybasic character of galactose-based glycosylated antitumor ether lipids for enhanced cytotoxic response By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00662C, Research ArticleRajat Arora, Ayan Mukherjee, Gilbert Arthur, Mark W. Nachtigal, Frank SchweizerWe describe the multi-step synthesis of different dibasic and tribasic galactosamine-based glycosylated antitumor ether lipids (GAELs) and their cytotoxic response in comparison to doxorubicin and cisplatin.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mo Development, biological evaluation, and molecular modelling of some benzene-sulfonamide derivatives as protein tyrosine phosphatase-1B inhibitors for managing diabetes mellitus and associated metabolic disorders By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00594E, Research ArticleNagat Ghareb, Khaled M. Darwish, Mohamed S. Nafie, Ranwa Elrayess, Noha M. Abourobe, Shaimaa A. Fattah, Reem M. Hazem, Eman T. Mehanna, Ranza ElrayessOne benzene-sulfonamide derivative exhibited potent protein tyrosine phosphatase-1B inhibition for managing diabetes mellitus and associated metabolic disorders.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mo Design, synthesis and mechanistic insights into triclosan derived dimers as potential anti-plasmodials By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00494A, Research Article Shekhar, Shefali Chowdhary, Joel Mosnier, Isabelle Fonta, Bruno Pradines, Vipan KumarIn pursuit of novel anti-plasmodial agents, a library of triclosan-based dimers both with and without a 1H-1,2,3 triazole core were designed, synthesized and evaluated in order to achieve a multitargeted approach.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mo Amides of moronic acid and morolic acid with the tripeptides MAG and GAM targeting antimicrobial, antiviral and cytotoxic effects By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4MD00742E, Research Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Uladzimir Bildziukevich, Lucie Cerna, Jana Trylčová, Marie Kvasnicova, Lucie Rárová, David Šaman, Petra Lovecká, Jan Weber, Zdenek WimmerA series of amides of the selected plant triterpenoids, moronic acid and morolic acid, with the tripeptides MAG and GAM was designed and synthesized. Two required tripeptides 5 and 10...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mo Novel benzenesulfonamides containing a dual triazole moiety with selective carbonic anhydrase inhibition and anticancer activity By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00617H, Research ArticleAida Buza, Cüneyt Türkeş, Mustafa Arslan, Yeliz Demir, Busra Dincer, Arleta Rifati Nixha, Şükrü BeydemirIn this research, a series of sulfonamides incorporating a 1,2,3-triazolyloxime substituted 1,2,3-triazolyl moiety was conceptualized, synthesized, and investigated as carbonic anhydrase inhibitors.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mo Azo derivatives of monoterpenes as anti-Helicobacter pylori agents: from synthesis to structure-based target investigation By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00511B, Research Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Francesco Melfi, Marialuigia Fantacuzzi, Simone Carradori, Ilaria D'Agostino, Alessandra Ammazzalorso, Noemi Mencarelli, Marialucia Gallorini, Mattia Spano, Paolo Guglielmi, Mariangela Agamennone, Sazan Haji Ali, Ali Al-Samydai, Francesca SistoMonoterpene-derived azo benzenes showed selective antibacterial activity against Helicobacter pylori with a safe profile. An in silico investigation highlighted the inosine 5'-monophosphate dehydrogenase enzyme as the putative target.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mo Synthesis and anti-tumor activity of new benzofuran-based chalcone derivatives as potent VEGFR-2 inhibitors By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00621F, Research ArticleChunfei Zhang, Yixin Liu, Xiao Zhang, Chunping Wan, Zewei MaoA series of novel benzofuran-based chalcone derivatives could be considered as potent VEGFR-2 inhibitors.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mo S-MGBs bearing amidine tail groups are potent, selective antiplasmodial agents By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00619D, Research Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Marina Perieteanu, Tayner Rodriguez Garzon, Leah M. C. McGee, Abedawn I. Khalaf, Colin J. Suckling, Rebecca Beveridge, Vicky M. Avery, Fraser J. Scott25 S-MGBs, including those bearing an amidine tail group, were investigated for their antiplasmodial, in vitro activity against 3D7 and Dd2 strains of P. falciparum. Several potent, and selective, hit compounds were identified.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mo Discovery of N-substituted-2-oxoindolin benzoylhydrazines as c-MET/SMO modulators in EGFRi-resistant non-small cell lung cancer By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00553H, Research ArticleStefano Tomassi, Benito Natale, Michele Roggia, Luisa Amato, Caterina De Rosa, Carminia Maria Della Corte, Emma Baglini, Giorgio Amendola, Anna Messere, Salvatore Di Maro, Elisabetta Barresi, Federico Da Settimo, Maria Letizia Trincavelli, Fortunato Ciardiello, Sabrina Taliani, Floriana Morgillo, Sandro CosconatiNon-small cell lung cancer (NSCLC), the leading cause of cancer-related mortality worldwide, poses a formidable challenge due to its heterogeneity and the emergence of resistance to targeted therapies.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mo Light enhanced cytotoxicity and antitumoral effect of a ruthenium-based photosensitizer inspired from natural alkaloids By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00600C, Research Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Gennaro Sanità, Maria Laura Alfieri, Barbara Carrese, Serena Damian, Vincenza Mele, Gaetano Calì, Brigida Silvestri, Sebastiano Marra, Susan Mohammadi, Giuseppina Luciani, Paola Manini, Annalisa LambertiBiological assays carried out on melanoma and breast cancer cells highlighted the role of light in boosting the cytotoxic effect of a ruthenium complex featuring a dihydroisoquinoline ligand suggesting applications in photodynamic therapy.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mo Changes in train services notified due to demolition of old bridge near Tiruchi junction By www.thehindu.com Published On :: Tue, 05 Nov 2024 17:30:53 +0530 Full Article Tiruchirapalli
mo Frequent traffic snarls pose hardship to motorists in Tiruchi By www.thehindu.com Published On :: Tue, 05 Nov 2024 17:45:36 +0530 It is common to see vehicles lining up for a long distance from the traffic signal near Cauvery bridge to Anna Statue. Full Article Tiruchirapalli
mo TNSTC Kumbakonam Division mops up ₹17.13 crore in four days By www.thehindu.com Published On :: Wed, 06 Nov 2024 18:59:26 +0530 Full Article Tiruchirapalli
mo Deputy CM releases commemorative flag of Bharat Scouts and Guides By www.thehindu.com Published On :: Thu, 07 Nov 2024 17:48:40 +0530 Full Article Tiruchirapalli