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Lactobacillus plantarum 69-2 combined with α-lactalbumin hydrolysate alleviates DSS-induced ulcerative colitis through the TLR4/NF-κB inflammatory pathway and the gut microbiota in mice

Food Funct., 2024, 15,10987-11004
DOI: 10.1039/D4FO02975E, Paper
Yue Ma, Chuanbing Hu, Jing Zhang, Cong Xu, Lizhi Ma, Yunhe Chang, Muhammad Altaf Hussain, Jiage Ma, Juncai Hou, Zhanmei Jiang
Ulcerative colitis (UC), an inflammatory bowel disease, seriously affects people's quality of life.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Aronia melanocarpa extract extends the lifespan and health-span of Caenorhabditis elegans via mitogen-activated protein kinase 1

Food Funct., 2024, 15,11020-11035
DOI: 10.1039/D4FO02479F, Paper
Huan Zhang, Zhigang Zhu, Wenjing Wei, Zekun Liu, Huiji Zhou, Yueling Gong, Xinlei Yan, Jun Du, Houkai Li, Liang Chen, Lili Sheng
Aronia melanocarpa (AM) was shown to promote the lifespan and health-span of C. elegans via the PMK-1 pathway, highlighting the potential of AM as a dietary supplement for delaying aging.
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Lacticaseibacillus plantarum postbiotics prepared by the combined technique of pasteurization and ultrasound: effective measures to alleviate obesity based on the SCFAs-GPR41/GPR43 signaling pathway

Food Funct., 2024, 15,11005-11019
DOI: 10.1039/D4FO03591G, Paper
Chao Miao, Linge Wang, Huabing Wang, Yu Shen, Chaoxin Man, Wei Zhang, Yu Zhang, Qianyu Zhao, Yujun Jiang
Postbiotics prepared by ultrasound and pasteurization are used for the alleviation of obesity.
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Cardamonin protects against diabetic cardiomyopathy by activating macrophage NRF2 signaling through molecular interaction with KEAP1

Food Funct., 2024, 15,11083-11095
DOI: 10.1039/D4FO03543G, Paper
Wenshan Nan, Jialin Yin, Wenhao Hao, Huali Meng, Junduo Wu, Xiao Yin, Hao Wu
Cardamonin inhibited macrophage M1 polarization in diabetic cardiomyopathy by binding to KEAP1, leading to the dissociation of NRF2 from KEAP1. This promoted NRF2 nuclear translocation and antioxidant gene expression in M1 polarized macrophages.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Metagenomic and transcriptomic profiling of the hypoglycemic and hypotriglyceridemic actions of Tremella fuciformis-derived polysaccharides in high-fat-diet- and streptozotocin-treated mice

Food Funct., 2024, 15,11096-11114
DOI: 10.1039/D4FO01870B, Paper
Xiaofei Xu, Xiaofei Liu, Liyan Liu, Jin Chen, Jingjing Guan, Donghui Luo
Tremella fuciformis polysaccharides exhibit hypoglycemic and hypotriglyceridemic activities through altering the taxonomic and functional attributes of the gut microbiota and modulating gene expression in the liver.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Up-regulation of myelin-associated glycoprotein is associated with the ameliorating effect of omega-3 polyunsaturated fatty acids on Alzheimer's disease progression in APP–PS1 transgenic mice

Food Funct., 2024, 15,11236-11251
DOI: 10.1039/D4FO03355H, Paper
Yan Shao, Fei Li, Bo Zou, Yanling Jin, Xiaoyang Wang, Liting Wang, Youying Huang, Yu Xie, Wei Sun, Jing X. Kang, Kai Liu, Yi Huang, Wei Huang, Bin Wang
Our study showed that MAG upregulation might be the new regulatory mechanism for omega-3 PUFAs to exert AD protective effects, which is helpful for expanding our understanding of the health-promoting effects of omega-3 PUFAs.
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Human milk oligosaccharides and milk fat globule membrane reduce allergic reactions in mice through the modulation of gut microbiota and metabolic functions

Food Funct., 2024, 15,11252-11265
DOI: 10.1039/D4FO03851G, Paper
Xinzhang Chen, Shengjun Yang, Zhengtao Guo, Bailiang Li, Zhongjiang Wang, Lianzhou Jiang
Human milk oligosaccharides (HMOs) and the milk fat globule membrane (MFGM) represent novel treatments for cow's milk allergy (CMA).
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Techno-functional, antioxidant, and amino acid characterization of hydrolyzed bioactive peptides from coconut (Cocos nucifera L.) meal protein

Food Funct., 2024, 15,11266-11279
DOI: 10.1039/D4FO02741H, Paper
Roshanak Zolqadri, Zahra Akbarbaglu, Khashayar Sarabandi, Seyed Hadi Peighambardoust, Seid Mahdi Jafari, Amin Mousavi Khaneghah
In this study, the techno-functional characteristics and nutritional value of coconut meal protein (CMP) and the obtained polypeptides by alcalase (H-Alc), trypsin (H-Try), pancreatin (H-Pan), and pepsin (H-pep) were investigated.
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Allergenicity evaluation of an extensively hydrolyzed infant formula based on cow milk protein

Food Funct., 2024, 15,11036-11046
DOI: 10.1039/D4FO03582H, Paper
Hongbo Li, Lin Yang, Jiayi Li, Quan Gao, Tiantian Liu, Yang Zou, Xiaohong Chen, Hongjuan Li, Jinghua Yu
We developed an extensively hydrolyzed infant formula (EHF) with a protein composition similar to breast milk (whey protein-to-casein ratio of 6 : 4) and evaluated its sensitization in vitro and in vivo.
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Development of Pickering water-in-oil emulsions using a dual stabilization of candelilla wax and acylated EGCG derivatives to enhance the survival of probiotics (Lactobacillus plantarum) powder

Food Funct., 2024, 15,11141-11157
DOI: 10.1039/D4FO01342E, Paper
Zhaojuan Shi, Jun Wu, Xingting Wang, Tongqiao Nie, Qingmei Zeng, Chuanxun Yuan, Risheng Jin
Candelilla wax reinforced the stability of Pickering W/O emulsions with a three-dimensional crystal network. The oil phase volume fraction of the emulsions showed dramatic differences in protecting probiotic viability from environmental stresses.
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Alleviating effect of whey protein supplementation on oxidative stress in hypothyroidism

Food Funct., 2024, 15,11158-11168
DOI: 10.1039/D4FO03186E, Paper
Ann Liya Sajan, Jenat Pazheparambil Jerom, Bhagyasree Rajasekharan Nair, Devanandana Dileep Kumar Sajitha, Reshma Soman, Ajmal Jalal, Raveendran Harikumaran Nair
Supplementation with whey protein is effective for treating hypothyroidism-associated oxidative stress by enhancing the antioxidant system, reducing lipid peroxidation and maintaining cellular ionic balance.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Ellagic acid ameliorates alcohol-induced cognitive and social dysfunction through the gut microbiota-mediated CCL21-CCR7 axis

Food Funct., 2024, 15,11186-11205
DOI: 10.1039/D4FO03985H, Paper
Hongbo Zhang, Min Luo, Yinuo Li, Lu Liu, Ji Bian, Lan Gong, Caian He, Lin Han, Min Wang
EA enhanced the abundance of beneficial bacteria as well as their derived metabolites, thereby inhibiting chronic alcohol-induced neuroinflammation via regulation of the gut microbiota-mediated CCL21-CCR7 axis, ultimately ameliorating AICSD.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Human Milk Metals and Metalloids Shape Infant Microbiota

Food Funct., 2024, Accepted Manuscript
DOI: 10.1039/D4FO01929F, Paper
Open Access
Eduard Flores Ventura, Manuel Bernabeu, Belén Callejón Leblic, Raúl Cabrera-Rubio, Laxmi Yeruva, Javier Estañ-Capell, Cecilia Martínez-Costa, Tamara García-Barrera, Maria Carmen Collado
Background: The profile of metal (loid)s in human milk is essential for infant growth and development, yet its impact on the development of the infant microbiota remains unclear. Elements such...
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Ergothioneine improves cognitive function by ameliorating mitochondrial damage and decreasing neuroinflammation in a D-galactose-induced aging model

Food Funct., 2024, Advance Article
DOI: 10.1039/D4FO02321H, Paper
Fangyang Chen, Botao Wang, Xin Sun, Yage Wang, Ruiyan Wang, Kaikai Li
EGT intervention significantly improved D-galactose induced oxidative stress, neuroinflammation, and mitochondrial function, resulting in the alleviation of memory injury.
To cite this article before page numbers are assigned, use the DOI form of citation above.
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Oral administration of cranberry-derived exosomes attenuates murine premature ovarian failure in association with changes in the specific gut microbiota and diminution in ovarian granulosa cell PANoptosis

Food Funct., 2024, Advance Article
DOI: 10.1039/D4FO03468F, Paper
Open Access
Zeyu Cui, Te Liu, Yichao Wen, Weihao Li, Jianghong Xu, Yingjuan Chen, Danping Chen, Ying Zhu
We confirmed that oral administration of cranberry-derived exosomes attenuated murine POF by modulating the gut microbiota and decreasing ovarian granulosa cell PANoptosis.
To cite this article before page numbers are assigned, use the DOI form of citation above.
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Promote millets for nutritional security

Several studies show that consumption of millets reduce the risk of heart disease and have a positive impact on anaemia apart from controlling blood pressure




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Editorial. India needs a stable population, not more children

Southern States’ concerns need to be addressed by the Finance panel




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Editorial. BRICS’ financial ambitions cannot be wished away

BRICS countries have expressed the need for developing a platform where central bank digital currencies can be linked. This will reduce intermediation costs




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Another star makes a political debut

Vijay’s entry adds an interesting twist to the 2026 TN elections



  • From the Viewsroom

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Dhootha Review

At the end of eight episodes, the climax is bound to leave you with questions but it would be fair to say that the two-episode backstory and the characters seemed far more interesting than the six-episode drama and tension that led to it, observes Divya Nair.




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Lootere Review

Lootere deserves points for originality and novelty, observes Deepa Gahlot.




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Bade Miyan Chote Miyan Review

Forget comic chops, you'll not find an ounce of camaraderie between Akshay Kumar and Tiger Shroff as they go about firing ammo and flexing abs at a zombie-like army for nearly three excruciating hours of this noisy drivel, observes Sukanya Verma.




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Ranneeti: Balakot And Beyond Review

Ranneeti: Balakot And Beyond veers between intriguing and boring, observes Deepa Gahlot.




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Chhota Bheem: The Curse of Damyaan Review

Chhota Bheem: The Curse of Damyaan is a fun movie, its adventurous story and lovable characters make it worth watching with family, notes Riddhi Soni.




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Kota Factory 3 Review

The new season takes the students out of their preoccupation with studies to other problems -- jealousy of another's easy success, a blip in a romance, financial crunch, meltdowns, discovers Deepa Gahlot.




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The Wild Robot Review

The Wild Robot is delightful children's fare and a meaningful watch for grown-ups, discovers Mayur Sanap.




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The Miranda Brothers Review

The Miranda Brothers is short on humour, romance and real drama, observes Deepa Gahlot.




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Farmers in Punjab block highways in protest against 'tardy' paddy procurement




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Treesa-Gayatri make first round exit from Kumamoto Masters Japan

The world No. 20 Indian pair was brushed aside 16-21, 16-21 by Hsu Yin-Hui and Lin Yin-Hui, ranked 24, in just 36 minutes in their women's doubles round 32 of clash of the Super 500 tournament




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Hyundai Motor consolidated Q2 net skids on weak sentiments

Revenue from operations declined by 7.5% to ₹17,260 crore due to Red Sea crisis, while operational and cost efficiencies provided some positive support, the carmaker said in a statement




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NHM left over ₹324 crore unspent of the funds it got to fight COVID-19: D’Cunha commission report




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As UPPSC aspirants protest for 2nd day, U.P. govt. faces flak

Thousands of youth are protesting outside the UPPSC headquarters in Prayagraj against the conduct of Civil Services (preliminary), Review Officer/Assistant Review Officer examination in multiple shifts and against normalisation of score. UPPSC argues when exams are held on multiple days or shifts for a single recruitment notification, the score normalisation process is essential in evaluating the results as the difficulty level of the paper in each shift/day varies.




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Education not a prerogative of the ‘upper caste‘, says Siddaramaiah

Ramayana, Mahabharata authored by “lower castes”, says CM




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Star hotels, resorts likely to come up near Bhogapuram international airport

A Tata group company seeks allocation of land, another company recently completes a beach resort in Srikakulam




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Suryanarkoil Saivite mutt locked as pontiff leaves following public protest




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CM lays foundation stone for development projects, inaugurates new works in H.D. Kote

Drinking water schemes get emphasis




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Odisha’s panchayats witness spate of no-confidence motions after BJP’s victory in State

The trend signals a shift in the grassroots power dynamics across the State with BJP venturing to claim even more of the BJD’s political territory




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Bomb threat to hotel in Erode




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Man arrested for murdering fruit seller in Tiruvottiyur




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Chaavadikota hill, the newest destination in Maredumilli forests beckons tourists 

With its breathtaking sunrise and sunset views, and pristine waterfalls, the emerging destination offers a treat to nature lovers, and a possibility to experience the hospitality of the aboriginal tribes




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Anganwadi noonmeal pensioners stage protest in Krishnagiri




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BJP leaders slam Congress, accuse it of delivering false promises to garner votes

Former Union Minister Anurag Thakur takes a dig at Congress leader Rahul Gandhi




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Cost of commotion: each MCD House session comes with a ₹3 lakh tab




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Language learning should not be imposed, says Venkaiah Naidu




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Delhi HC pulls up govt. for not complying with its order on shifting Asha Kiran shelter home inmates




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MP byelections: Last-minute tensions ahead of voting after firing in Vijaypur

The byelections, first since the Lok Sabha elections, have somethings at stake for both the Bharatiya Janata Party and the Congress




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Jharkhand first phase of polling LIVE updates: Voting begins for 43 seats

Former CM is contesting on a BJP ticket for the first time, while six State Cabinet Ministers are also among 683 candidates in the first phase




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Morning Digest: British writer Samantha Harvey’s space-station novel ‘Orbital’ wins Booker Prize for fiction; Big names face test as Jharkhand votes in Phase I, and more

Here is a select list of stories to start the day




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Union Minister stresses on the need to promote Ayush systems of medicine




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Bypolls LIVE: Voting begins for 31 Assembly seats in 10 States

Congress general secretary Priyanka Gandhi Vadra is making her electoral debut in Wayanad