y Chromosome 11 open reading frame 30 (C11orf30), calpain small subunit 1 (CAPNS1; CAPN4), signal transducer and activator of transcription 6 (STAT6) and ankyrin repeat domain 27 (ANKRD27) as diagnostic markers for eosinophilic esophagitis (EoE) By feeds.nature.com Published On :: 2014-12-18 Genomewide association studies identified four genes that could serve as diagnostic markers and/or therapeutic targets for EoE. Full Article
y Tumor-selective delivery of antisense oligomers (antimiRs) against oncogenic microRNAs By feeds.nature.com Published On :: 2014-12-18 miRNA-targeted antimiRs conjugated to a peptide with a low pH–induced transmembrane structure (pHLIP) could help treat solid tumors. Full Article
y Nanomolar-scale, high throughput chemical synthesis of drug-like molecules By feeds.nature.com Published On :: 2014-12-18 A high throughput, miniaturized chemical synthesis platform could enable rapid discovery of lead compounds. Full Article
y Dermatophagoides pteronyssinus peptidase 1 (DERP1) By feeds.nature.com Published On :: 2014-12-18 In vitro and rat studies suggest inhibiting the enzymatic activity of house dust mite (HDM) allergens could help treat allergic asthma. Full Article
y Globohexaosylceramide (globo-H); stage-specific embryonic antigen-3 (SSEA-3); SSEA-4 By feeds.nature.com Published On :: 2014-12-18 Mouse studies suggest chemically modified carbohydrate conjugates could be useful as antigens for the development of cancer vaccines. Full Article
y Cyclin dependent kinase 7 (CDK7); v-myc myelocytomatosis viral related oncogene neuroblastoma derived (MYCN; NMYC) By feeds.nature.com Published On :: 2014-12-18 In vitro and mouse studies suggest THZ1, a covalent CDK7 inhibitor, could help treat neuroblastoma and other cancers driven by MYCN and other c-MYC (MYC)-family oncoproteins. Full Article
y Estrogen receptor; LYN kinase (LYN); phosphoinositide 3-kinase (PI3K) By feeds.nature.com Published On :: 2014-12-18 Studies in mice and human samples suggest inhibiting LYN could help treat estrogen receptor–positive breast cancers resistant to anti-estrogen therapy. Full Article
y Pac1/LIS1 stabilizes an uninhibited conformation of dynein to coordinate its localization and activity By feeds.nature.com Published On :: 2020-04-27 Full Article
y Tissue-resident ductal macrophages survey the mammary epithelium and facilitate tissue remodelling By feeds.nature.com Published On :: 2020-04-27 Full Article
y Myeloid PTEN promotes chemotherapy-induced NLRP3-inflammasome activation and antitumour immunity By feeds.nature.com Published On :: 2020-05-04 Full Article
y In vitro capture and characterization of embryonic rosette-stage pluripotency between naive and primed states By feeds.nature.com Published On :: 2020-05-04 Full Article
y Differentiation of transplanted haematopoietic stem cells tracked by single-cell transcriptomic analysis By feeds.nature.com Published On :: 2020-05-04 Full Article
y MicroRNA binding site polymorphism in inflammatory genes associated with colorectal cancer: literature review and bioinformatics analysis By feeds.nature.com Published On :: 2020-03-23 Full Article
y In vivo antitumor activity by dual stromal and tumor-targeted oncolytic measles viruses By feeds.nature.com Published On :: 2020-03-31 Full Article
y Oncolytic adenovirus encoding LIGHT (TNFSF14) inhibits tumor growth via activating anti-tumor immune responses in 4T1 mouse mammary tumor model in immune competent syngeneic mice By feeds.nature.com Published On :: 2020-04-20 Full Article
y TMB: a promising immune-response biomarker, and potential spearhead in advancing targeted therapy trials By feeds.nature.com Published On :: 2020-04-28 Full Article
y Immunostimulatory oncolytic virotherapy for multiple myeloma targeting 4-1BB and/or CD40 By feeds.nature.com Published On :: 2020-05-01 Full Article
y UNC5B mediates G2/M phase arrest of bladder cancer cells by binding to CDC14A and P53 By feeds.nature.com Published On :: 2020-05-06 Full Article
y High-purity orbital angular momentum states from a visible metasurface laser By feeds.nature.com Published On :: 2020-04-27 Full Article
y Author Correction: Quantum wave–particle superposition in a delayed-choice experiment By feeds.nature.com Published On :: 2020-04-28 Full Article
y Engineering nanomedicines through boosting immunogenic cell death for improved cancer immunotherapy By feeds.nature.com Published On :: 2020-04-21 Full Article
y Cardamonin protects against lipopolysaccharide-induced myocardial contractile dysfunction in mice through Nrf2-regulated mechanism By feeds.nature.com Published On :: 2020-04-21 Full Article
y Nintedanib inhibits keloid fibroblast functions by blocking the phosphorylation of multiple kinases and enhancing receptor internalization By feeds.nature.com Published On :: 2020-04-23 Full Article
y An in vitro Förster resonance energy transfer-based high-throughput screening assay identifies inhibitors of SUMOylation E2 Ubc9 By feeds.nature.com Published On :: 2020-04-27 Full Article
y Compound LM9, a novel MyD88 inhibitor, efficiently mitigates inflammatory responses and fibrosis in obesity-induced cardiomyopathy By feeds.nature.com Published On :: 2020-04-27 Full Article
y Nanomedicines based on nanoscale metal-organic frameworks for cancer immunotherapy By feeds.nature.com Published On :: 2020-04-30 Full Article
y Head-to-head trials in inflammatory bowel disease: past, present and future By feeds.nature.com Published On :: 2020-04-17 Full Article
y Effects of acute and repeated treatment with methocinnamox, a mu opioid receptor antagonist, on fentanyl self-administration in rhesus monkeys By feeds.nature.com Published On :: 2020-05-06 Full Article
y Cannabinoid CB<sub>2</sub> receptors mediate the anxiolytic-like effects of monoacylglycerol lipase inhibition in a rat model of predator-induced fear By feeds.nature.com Published On :: 2020-05-06 Full Article
y A roadmap for development of neuro-oscillations as translational biomarkers for treatment development in neuropsychopharmacology By feeds.nature.com Published On :: 2020-05-06 Full Article
y Evaluating the impact of trauma and PTSD on epigenetic prediction of lifespan and neural integrity By feeds.nature.com Published On :: 2020-05-07 Full Article
y Δ<sup>9</sup>-Tetrahydrocannabinol (THC) impairs visual working memory performance: a randomized crossover trial By feeds.nature.com Published On :: 2020-05-09 Full Article
y Author Correction: Insights into parathyroid hormone secretion By feeds.nature.com Published On :: 2020-04-20 Full Article
y Obesity affects skeletal muscle ketone oxidation By feeds.nature.com Published On :: 2020-04-20 Full Article
y Obesity and impaired metabolic health in patients with COVID-19 By feeds.nature.com Published On :: 2020-04-23 Full Article
y Nonoperative treatment of traumatic spinal injuries in Tanzania: who is not undergoing surgery and why? By feeds.nature.com Published On :: 2020-04-29 Full Article
y Incidence of acute spinal cord injury in South Korea does not reflect a sizable number of traumatic spinal cord injuries By feeds.nature.com Published On :: 2020-04-30 Full Article
y A more accurate incidence of acute spinal cord injury in South Korea can be estimated by the national health insurance system By feeds.nature.com Published On :: 2020-04-30 Full Article
y Wheelchair propulsion fatigue thresholds in electromyographic and ventilatory testing By feeds.nature.com Published On :: 2020-05-04 Full Article
y Development of a skin temperature map for dermatomes in individuals with spinal cord injury: a cross-sectional study By feeds.nature.com Published On :: 2020-05-05 Full Article
y Impact of COVID-19 outbreak on spinal pathology: single center first impression By feeds.nature.com Published On :: 2020-05-05 Full Article
