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Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson’s disease




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Author Correction: <i>Cdkn1a</i> deletion improves stem cell function and lifespan of mice with dysfunctional telomeres without accelerating cancer formation




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Elevated sorbitol underlies a heritable neuropathy




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Biallelic mutations in <i>SORD</i> cause a common and potentially treatable hereditary neuropathy with implications for diabetes




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ZBP1 (DAI/DLM-1) promotes osteogenic differentiation while inhibiting adipogenic differentiation in mesenchymal stem cells through a positive feedback loop of Wnt/β-catenin signaling




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Correction to: AFF1 and AFF4 differentially regulate the osteogenic differentiation of human MSCs




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Dystrophic calcification and heterotopic ossification in fibrocartilaginous tissues of the spine in diffuse idiopathic skeletal hyperostosis (DISH)




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uPAR antibody (huATN-658) and Zometa reduce breast cancer growth and skeletal lesions




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Ionomycin ameliorates hypophosphatasia via rescuing alkaline phosphatase deficiency-mediated L-type Ca<sup>2+</sup> channel internalization in mesenchymal stem cells




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Accesibilidad informacional y diversidad funcional en el contexto universitario: el caso de la Universidad Complutense de Madrid

Cuevas-Cerveró, Aurora and Razquín-Zazpe, Pedro and Parra-Valero, Pablo and Barrios-Martínez, Cristina and Gómez-Hernández, José-Antonio . Accesibilidad informacional y diversidad funcional en el contexto universitario: el caso de la Universidad Complutense de Madrid., 2020 In: Competencia en Información y Políticas para Educación Superior: Estudos Hispano-Brasileiros. Universidad Complutense de Madrid, pp. 132-146. [Book chapter]




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e-EMGDE, RIC, NEDA y las normas de codificación: más allá de un perfil de aplicación en archivos

Baños-Moreno, María-José and Valentín-Ruiz, Francisco-José and Blázquez-Martín-de-las-Mulas, Antonio e-EMGDE, RIC, NEDA y las normas de codificación: más allá de un perfil de aplicación en archivos., 2019 . In IV Congreso ISKO España-Portugal, Barcelona, 11-12 de julio de 2019. [Conference paper]




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El aspecto social de la biblioteca pública y la inclusión social de las minorías

Saurin-Parra, Julia . El aspecto social de la biblioteca pública y la inclusión social de las minorías., 2019 In: El libro y la lectura en recintos penitenciarios. Gráfica Nacional, pp. 73-81. [Book chapter]




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El libro y la lectura en los recintos penitenciarios de la región de Valparaíso

Sequeiros, Paula and Silveira, Fabrício José Nascimento da and Rivera Donoso, Miguel and Armingol Jaime, Karla and Díaz Rubio, Sara and Sáez Alarcón, Daniela and Muñoz Muño, Alexia and Saurin Parra, Julia and Cosgrove, Kimberly and Parra, Pablo and Barbosa, Andreza Gonçalves and Piñeiros, Gabriela . El libro y la lectura en los recintos penitenciarios de la región de Valparaíso., 2019 Universidad de Playa Ancha. [Book]




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Cosas de mujeres: lectura y penitenciaría

Sequeiros, Paula . Cosas de mujeres: lectura y penitenciaría., 2019 In: Las prácticas de lectura en los recintos penitenciarios de la región de Valparaíso. Universidad de Playa Ancha, pp. 91-101. [Book chapter]




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Leer, escribir y aprender con Internet. La función educativa de las bibliotecas y las tecnologías participativas de la web social

Gómez-Hernández, José-Antonio . Leer, escribir y aprender con Internet. La función educativa de las bibliotecas y las tecnologías participativas de la web social., 2008 In: Infodiversidad. La biblioteca como centro multicultural. Universidad de Guadalajara, pp. 55-74. [Book chapter]




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Educar para la transparencia y una ciudadanía informada: diseño, aplicación y evaluación del programa IRIS para alumnado de Bachillerato de la Región de Murcia (España)

Campillo-Meseguer, María-José and Galiano-Martínez, Antonio and Gómez-Hernández, José-Antonio and Hidalgo-Pérez, Antonio and López Aniorte, María-del-Carmen and Martínez-Navarro, Emilio and Molina-Molina, José and Mayor-Balsas, José-Manuel and Ros-Media, José Luis and Oliva-Palazón, Elena and Reverte-Martínez, Francisco-Manuel and Baeza-Hernández, María-José . Educar para la transparencia y una ciudadanía informada: diseño, aplicación y evaluación del programa IRIS para alumnado de Bachillerato de la Región de Murcia (España)., 2020 In: Competencias en Información y Políticas para Educación Superior: Estudios Hispano-Brasileños, volumen 1. Universidad Complutense de Madrid, pp. 123-138. [Book chapter]




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Impact of Covid-19 on the media system. Communicative and democratic consequences of news consumption during the outbreak // Impacto del Covid-19 en el sistema de medios. Consecuencias comunicativas y democráticas del consumo de noticias durante el

Casero-Ripollés, Andreu Impact of Covid-19 on the media system. Communicative and democratic consequences of news consumption during the outbreak // Impacto del Covid-19 en el sistema de medios. Consecuencias comunicativas y democráticas del consumo de noticias durante el brote. El profesional de la información, 2020, vol. 29, n. 2. [Journal article (Unpaginated)]




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Retweeting Covid-19 disability issues: Risks, support and outrage

Thelwall, Mike and Levitt, Jonathan M. Retweeting Covid-19 disability issues: Risks, support and outrage. El profesional de la información, 2020, vol. 29, n. 2. [Journal article (Unpaginated)]




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Comunicación corporativa, relaciones públicas y gestión del riesgo reputacional en tiempos del Covid-19

Xifra, Jordi Comunicación corporativa, relaciones públicas y gestión del riesgo reputacional en tiempos del Covid-19. El profesional de la información, 2020, vol. 29, n. 2. [Journal article (Unpaginated)]




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Ritmo de crecimiento diario de la producción científica sobre Covid-19. Análisis en bases de datos y repositorios en acceso abierto

Torres-Salinas, Daniel Ritmo de crecimiento diario de la producción científica sobre Covid-19. Análisis en bases de datos y repositorios en acceso abierto. El profesional de la información, 2020, vol. 29, n. 2. [Journal article (Unpaginated)]




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La radio: el medio que mejor se comporta en las crisis. Hábitos de escucha, consumo y percepción de los oyentes de radio durante el confinamiento por el Covid-19

Rodero, Emma La radio: el medio que mejor se comporta en las crisis. Hábitos de escucha, consumo y percepción de los oyentes de radio durante el confinamiento por el Covid-19. El profesional de la información, 2020, vol. 92, n. 3. [Journal article (Unpaginated)]




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Comunicación y crisis del coronavirus en España. Primeras lecciones // Communication and coronavirus crisis in Spain. First lessons

Costa-Sánchez, Carmen and López-García, Xosé Comunicación y crisis del coronavirus en España. Primeras lecciones // Communication and coronavirus crisis in Spain. First lessons. El profesional de la información, 2020, vol. 29, n. 3. [Journal article (Unpaginated)]




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Noticias sobre Covid-19 y 2019-nCoV en medios de comunicación de España: el papel de los medios digitales en tiempos de confinamiento // News on Covid-19 and 2019-nCoV in Spanish media: The role of digital media in times of confinement

Lázaro-Rodríguez, Pedro and Herrera-Viedma, Enrique Noticias sobre Covid-19 y 2019-nCoV en medios de comunicación de España: el papel de los medios digitales en tiempos de confinamiento // News on Covid-19 and 2019-nCoV in Spanish media: The role of digital media in times of confinement. El profesional de la información, 2020, vol. 29, n. 3. [Journal article (Unpaginated)]




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Carbon Taxes vs. Cap and Trade: Theory and Practice

How do the two major approaches to carbon pricing compare on relevant dimensions, including efficiency, cost-effectiveness, and distributional equity? This paper addresses this question by drawing on theories of policy instrument choice pertaining to the attributes — or merits — of the instruments.




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How to Topple Dictators and Transform Society

Nonviolent resistance scholar Erica Chenoweth explains the key ingredients of successful social movements.




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Comparative Grand Strategy: A Framework and Cases—Book Review

William James reviews Comparative Grand Strategy: A Framework and Cases edited by Thierry Balzacq,  Peter Dombrowski, and Simon Reich (Oxford University Press, 2019).




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H-Diplo Review Essay 192 on Lawson. Anatomies of Revolution

Emily Whalen reviews Anatomies of Revolution by George Lawson (Cambridge: Cambridge University Press, 2019).




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How Do Past Presidents Rank in Foreign Policy?

How do presidents incorporate morality into decisions involving the national interest? Moral considerations explain why Truman, who authorized the use of nuclear weapons in Japan during World War II, later refused General MacArthur's request to use them in China during the Korean War. What is contextual intelligence, and how does it explain why Bush 41 is ranked first in foreign policy, but Bush 43 is found wanting? Is it possible for a president to lie in the service of the public interest? In this episode, Professor Joseph S. Nye considers these questions as he explores the role of morality in presidential decision-making from FDR to Trump.




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COVID-19 Pandemic Accelerates the Rise of Digital Payments

Could using the cash in your pocket have the potential to spread covid-19? That question has rarely appeared in the news, but many governments and leaders in the digital payments industry are wondering how the virus might impact the use of cash. Several countries have already taken drastic measures to limit circulation of bank notes. Could such interventions lead to the end of cash payments?




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The Global Pandemic Has Spawned New Forms of Activism — and They're Flourishing

The authors have identified nearly 100 distinct methods of nonviolent action that include physical, virtual and hybrid actions.




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Carmen Reinhart Says Argentina’s Debt Workout Won’t Be Its Last

Argentina’s latest effort to restructure its overseas debt probably won’t be its last, according to Harvard University economist Carmen Reinhart, who has sounded alarms over coming emerging markets crises in Venezuela and Turkey.




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Genome-wide association study of semen volume, sperm concentration, testis size, and plasma inhibin B levels




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Intronic variant in <i>IQGAP3</i> associated with hereditary neuropathy with proximal lower dominancy, urinary disturbance, and paroxysmal dry cough




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Correction: Importance of gastric cancer for the diagnosis and surveillance of Japanese Lynch syndrome patients




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Analyses of breakpoint junctions of complex genomic rearrangements comprising multiple consecutive microdeletions by nanopore sequencing




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Genome-wide association study identifies zonisamide responsive gene in Parkinson’s disease patients




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Correction to ‘Genotyping of Malaysian G6PD-deficient neonates by reverse dot blot flow-through hybridisation’




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Interpretation of omics data analyses




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Why is the United States So Bad at Foreign Policy?

Stephen Walt writes that the United States' unusual historical experience, geographic isolation, large domestic market, and general ignorance have weakened its ability to make viable foreign-policy strategies.




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What Makes for a Moral Foreign Policy?

Joseph Nye's new book rates the efforts of presidents from FDR to Trump.




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The Low-Yield Nuclear Warhead: A Dangerous Weapon Based on Bad Strategic Thinking

In the unintuitive world of nuclear weapons strategy, it’s often difficult to identify which decisions can serve to decrease the risk of a devastating nuclear conflict and which might instead increase it. Such complexity stems from the very foundation of the field: Nuclear weapons are widely seen as bombs built never to be used. Historically, granular—even seemingly mundane—decisions about force structure, research efforts, or communicated strategy have confounded planners, sometimes causing the opposite of the intended effect.




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Accumulating Evidence Using Crowdsourcing and Machine Learning: A Living Bibliography about Existential Risk and Global Catastrophic Risk

The study of existential risk — the risk of human extinction or the collapse of human civilization — has only recently emerged as an integrated field of research, and yet an overwhelming volume of relevant research has already been published. To provide an evidence base for policy and risk analysis, this research should be systematically reviewed. In a systematic review, one of many time-consuming tasks is to read the titles and abstracts of research publications, to see if they meet the inclusion criteria. The authors show how this task can be shared between multiple people (using crowdsourcing) and partially automated (using machine learning), as methods of handling an overwhelming volume of research.




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The Need for Creative and Effective Nuclear Security Vulnerability Assessment and Testing

Realistic, creative vulnerability assessment and testing are critical to finding and fixing nuclear security weaknesses and avoiding over-confidence. Both vulnerability assessment and realistic testing are needed to ensure that nuclear security systems are providing the level of protection required. Systems must be challenged by experts thinking like adversaries, trying to find ways to overcome them. Effective vulnerability assessment and realistic testing are more difficult in the case of insider threats, and special attention is needed. Organizations need to find ways to give people the mission and the incentives to find nuclear security weaknesses and suggest ways they might be fixed. With the right approaches and incentives in place, effective vulnerability assessment and testing can be a key part of achieving and sustaining high levels of nuclear security.




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The Risks and Rewards of Emerging Technology in Nuclear Security

Nuclear security is never finished. Nuclear security measures for protecting all nuclear weapons, weapons-usable nuclear materials, and facilities whose sabotage could cause disastrous consequences should protect against the full range of plausible threats. It is an ongoing endeavor that requires constant assessment of physical protection operations and reevaluation of potential threats. One of the most challenging areas of nuclear security is how to account for the impact–positive and negative—of non-nuclear emerging technologies. The amended Convention on the Physical Protection of Nuclear Material (amended CPPNM) states it should be reviewed in light of the prevailing situation, and a key part of the prevailing situation is technological evolution. Therefore, the upcoming review conference in 2021, as well as any future review conferences, should examine the security threats and benefits posed by emerging technologies.




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The Past and Potential Role of Civil Society in Nuclear Security

Civil society has played a very important role in nuclear security over the years, and its role could be strengthened in the future. Some nuclear organizations react against the very idea of civil society involvement, thinking of only one societal role—protesting. In fact, however, civil society has played quite a number of critical roles in nuclear security over the years, including highlighting the dangers of nuclear terrorism; providing research and ideas; nudging governments to act; tracking progress and holding governments and operators accountable; educating the public and other stakeholders; promoting dialogue and partnerships; helping with nuclear security implementation; funding initial steps; and more. Funding organizations (both government and non-government) should consider ways to support civil society work and expertise focused on nuclear security in additional countries. Rather than simply protesting and opposing, civil society organizations can help build more effective nuclear security practices around the world.




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Assessing Progress on Nuclear Security Action Plans

Participants at the final Nuclear Security Summit in 2016 agreed on “action plans” for initiatives they would support by five international organizations and groups—the International Atomic Energy Agency, the Global Initiative to Combat Nuclear Terrorism, INTERPOL, the United Nations, and the Global Partnership Against the Spread of Weapons and Materials of Destruction. These institutions were supposed to play key roles in bolstering ongoing nuclear security cooperation after the summit process ended. The action plans were modest documents, largely endorsing activities already underway, and there have been mixed results in implementing them. To date, these organizations have not filled any substantial part of the role once played by the nuclear security summits.




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How Do Past Presidents Rank in Foreign Policy?

How do presidents incorporate morality into decisions involving the national interest? Moral considerations explain why Truman, who authorized the use of nuclear weapons in Japan during World War II, later refused General MacArthur's request to use them in China during the Korean War. What is contextual intelligence, and how does it explain why Bush 41 is ranked first in foreign policy, but Bush 43 is found wanting? Is it possible for a president to lie in the service of the public interest? In this episode, Professor Joseph S. Nye considers these questions as he explores the role of morality in presidential decision-making from FDR to Trump.




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Secrecy, Public Relations and the British Nuclear Debate

The opening of the British archives has seen historians uncover the secrets of the UK's nuclear weapons programme since the 1990s. While a growing number have sought to expose these former secrets, there has been less effort to consider government secrecy itself. What was kept a secret, when and why? And how and why, notably from the 1980s, did the British government decide to officially disclose greater information about the British nuclear weapons programme to Members of Parliament, journalists, defence academics and the tax-paying general public. 




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Public Testimony on Trump Administration Funding for Nuclear Theft Preventing Programs

A nuclear explosion detonated anywhere by a terrorist group would be a global humanitarian, economic, and political catastrophe. The current COVID-19 pandemic reminds us not to ignore prevention of and preparation for low-probability, high-consequence disasters. For nuclear terrorism, while preparation is important, prevention must be the top priority. The most effective strategy for keeping nuclear weapons out of the hands of terrorists is to ensure that nuclear materials and facilities around the world have strong and sustainable security. Every president for more than two decades has made strengthening nuclear security around the globe a priority. This includes the Trump administration, whose 2018 Nuclear Posture Review states: “[n]uclear terrorism remains among the most significant threats to the security of the United States, allies, and partners.”




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Living with Uncertainty: Modeling China's Nuclear Survivability

A simplified nuclear exchange model demonstrates that China’s ability to launch a successful nuclear retaliatory strike in response to an adversary’s nuclear first strike has been and remains far from assured. This study suggests that China’s criterion for effective nuclear deterrence is very low.