at Recent progress in selective estrogen receptor downregulators (SERDs) for the treatment of breast cancer By feeds.rsc.org Published On :: RSC Med. Chem., 2020, 11,438-454DOI: 10.1039/C9MD00570F, Review Article Shagufta, Irshad Ahmad, Shimy Mathew, Sofia RahmanThis article reviews the current progress in the development of SERDs as anti-breast cancer agents.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
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at Arylsulfonyl histamine derivatives as powerful and selective α-glucosidase inhibitors By feeds.rsc.org Published On :: RSC Med. Chem., 2020, 11,518-527DOI: 10.1039/C9MD00559E, Research ArticleM. I. Osella, M. O. Salazar, M. D. Gamarra, D. M. Moreno, F. Lambertucci, D. E. Frances, R. L. E. FurlanN α,Nτ-Di-4-trifluorobenzenesulfonyl histamine inhibits α-glucosidase in vitro reversibly and selectively with a Ki value of 11.6 μM, and shows an in vivo hypoglycemic effect in mice.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
at Chemotherapy for human schistosomiasis: how far have we come? What's new? Where do we go from here? By feeds.rsc.org Published On :: RSC Med. Chem., 2020, 11,455-490DOI: 10.1039/D0MD00062K, Review ArticleGodwin Akpeko Dziwornu, Henrietta Dede Attram, Samuel Gachuhi, Kelly ChibaleAfter a century since the first antimonial-based drugs were introduced to treat the disease, anti-schistosomiasis drug development is again at a bottleneck with only one drug, praziquantel, available for treatment purposes.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
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