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Recent progress in selective estrogen receptor downregulators (SERDs) for the treatment of breast cancer

RSC Med. Chem., 2020, 11,438-454
DOI: 10.1039/C9MD00570F, Review Article
Shagufta, Irshad Ahmad, Shimy Mathew, Sofia Rahman
This article reviews the current progress in the development of SERDs as anti-breast cancer agents.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Reversing binding sensitivity to A147T translocator protein

RSC Med. Chem., 2020, 11,511-517
DOI: 10.1039/C9MD00580C, Research Article
Sophie V. Vo, Samuel D. Banister, Isaac Freelander, Eryn L. Werry, Tristan A. Reekie, Lars M. Ittner, Michael Kassiou
A loss in binding affinity at A147T relative to WT TSPO is seen with most TSPO ligands. Provision of hydrogen-bonding opportunities on indole carboxamides rescues this loss in affinity.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Arylsulfonyl histamine derivatives as powerful and selective α-glucosidase inhibitors

RSC Med. Chem., 2020, 11,518-527
DOI: 10.1039/C9MD00559E, Research Article
M. I. Osella, M. O. Salazar, M. D. Gamarra, D. M. Moreno, F. Lambertucci, D. E. Frances, R. L. E. Furlan
N α,Nτ-Di-4-trifluorobenzenesulfonyl histamine inhibits α-glucosidase in vitro reversibly and selectively with a Ki value of 11.6 μM, and shows an in vivo hypoglycemic effect in mice.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Chemotherapy for human schistosomiasis: how far have we come? What's new? Where do we go from here?

RSC Med. Chem., 2020, 11,455-490
DOI: 10.1039/D0MD00062K, Review Article
Godwin Akpeko Dziwornu, Henrietta Dede Attram, Samuel Gachuhi, Kelly Chibale
After a century since the first antimonial-based drugs were introduced to treat the disease, anti-schistosomiasis drug development is again at a bottleneck with only one drug, praziquantel, available for treatment purposes.
The content of this RSS Feed (c) The Royal Society of Chemistry




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No spectators allowed at Hungarian GP

'We do believe that staging the event behind closed doors, which our fans can still watch on television, is preferable to not having a race at all.'




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Reducing operational costs in composites manufacturing / by Karen Snyder Travis

Online Resource




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Principles of reinforced concrete design / Mete A. Sozen, Toshikatsu Ichinose, Santiago Pujol

Online Resource




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Internet of vehicles: technologies and services toward smart cities: 6th International Conference, IOV 2019, Kaohsiung, Taiwan, November 18-21, 2019, Proceedings / Ching-Hsien Hsu, Sondès Kallel, Kun-Chan Lan, Zibin Zheng (eds.)

Online Resource




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Rütteldruckverdichtung als Plastodynamisches Problem: Deep vibration compaction as plastodynamic problem / W. Fellin

Online Resource




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Performance measures in snow and ice control operations / ICF with Athey Creek Consultants and Vaisala Inc

Barker Library - TE7.N275 no.889




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Hydraulic rubber dam: an effective water management technology / edited by Sabu Thomas, Ajay Vasudeo Rane, Abitha V.K., Krishnan Kanny, Aastha Dutta

Barker Library - TC540.H937 2019




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Belly-rippers, surgical innovation and the ovariotomy controversy / Sally Frampton

Hayden Library - RG481.F73 2018




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Blind spots: how unhealthy corridors harm communities and how to fix them / primary author, Heather Zaccaro

Rotch Library - HE308.Z33 2019




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Siliciclastic reserviors of the Arabian Plate / Edited by H. R. AlAnzi, R. A. Rahmani, R. J. Steel, O. M. Soliman

Dewey Library - TN876.A1 S55 2019




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Guide to truck activity data for emissions modeling / Christopher Porter, Timothy Grose, John Koupal, Kanok Boriboonsomsin, George Noel, Andrew Eilbert

Barker Library - TE7.N275 no.909




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Building a multimodal future: connecting real estate development and transportation demand management to ease gridlock / Justin B. Schor, Federico Tallis

Rotch Library - HE308.S36 2019




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Transportation workforce planning and development strategies / Robert Puentes, Alice Grossman, Brianne Eby, Alex Bond

Barker Library - TE7.N2755 no.543




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Global aspects of reputation and strategic management / editied by David L. Deephouse, Naomi A. Gardberg, and William Newburry

Dewey Library - HD30.28.G56 2019




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Street fights in Copenhagen: bicycle and car politics in a green mobility city / Jason Henderson and Natalie Marie Gulsrud

Rotch Library - HE311.D42 C6636 2019




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The vagina bible: the vulva and the vagina - separating the myth from the medicine / Jen Gunter, MD

Barker Library - RG268.G86 2019




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Admissibility and public availability of transit safety planning records / Committee to Review Evidentiary Protection for Public Transporation Safety Program Information, Transportation Research Board

Barker Library - TE7.N2774 no.326




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Managing state transportation research programs: a synthesis of highway practice / Donald Ludlow, Vivek Sakhrani, Camille Wu

Barker Library - TE7.N2755 no.522




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Tools to facilitate implementation of effective metropolitan freight transportation strategies / Bill Eisele [and 8 others]

Barker Library - TE7.N275 no.897




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Performance of longitudinal barriers on curved, superelevated roadway sections / Dhafer Marzougui; Cing-Dao "Steve" Kan; Umashankar Mahadevaiah; Fadi Tahan; Christopher Story; Stefano Dolci; Alberto Moreno; Kenneth S. Opiela; Richard Powers

Barker Library - TE7.N275 no.894




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Strategic thinking and writing Michael Edmondson, PhD

Dewey Library - HD30.28.E348 2019




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Prioritization of freight investment projects: a synthesis of highway practice / Mario M. Monsreal, Matthew Miller, Madison Metsker-Galarza, Madison Graham, Juan Carlos Villa

Barker Library - TE7.N2755 no.542




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Benchmarking and comparative meeasurement for effective performance management by transportation agencies / Joe Crossett, Anna Batista, Hyun-A Park, Hugh Louch, and Kim Voros

Barker Library - TE7.N275 no.902




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Designed for digital: how to architect your business for sustained success / Jeanne W. Ross, Cynthia M. Beath, and Martin Mocker

Dewey Library - HD30.2.R6637 2019




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Nodes in Transport Networks - Research, Data Analysis and Modelling: 16th Scientific and Technical Conference "Transport Systems. Theory and Practice 2019", Selected Papers / Elżbieta Macioszek, Nan Kang, Grzegorz Sierpiński, editors

Online Resource




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TRANSBALTICA XI: transportation science and technology: proceedings of the International Conference TRANSBALTICA, May 2-3, 2019, Vilnius, Lithuania / edited by Kasthurirangan Gopalakrishnan, Olegas Prentkovskis, Irina Jackiva, Raimundas Junevičius

Online Resource




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Organization design / edited by John Joseph (University of California, Irvine, USA), Oliver Baumann (University of Southern Denmark, Denmark), Richard Burton (Duke University, USA), Kannan Srikanth (Ohio State University, USA)

Dewey Library - HD30.28.O72 2019




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Decision-making for sustainable transport and mobility: multi actor multi criteria analysis / edited by Cathy Macharis (Professor, Vrije University Brussel-Research group MOBI (Mobility, Logistics and Automotive Technology), dep. BUTO, Belgium), Gino Baud

Rotch Library - HE305.D36 2018




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LRFD minimum flexural reinforcement requirements / Sri Sritharan, Hartanto Wibowo, Michael J. Rosenthal, Jacob N. Eull (Iowa State University) ; Jay Holombo (T.Y. Lin International)

Barker Library - TE7.N25 no.906




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Quantifying the effects of preservation treatments on pavement performance / Gonzalo R. Rada, James M. Bryce, Beth A. Visintine, R. Gary Hicks, DingXen Cheng

Barker Library - TE7.N275 no.858




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Cambridge handbook of open strategy / edited by David Seidl, Richard Whittington, Georg von Krogh

Dewey Library - HD30.28.C3479 2019




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Workforce optimization workbook for transportation construction projects / Timothy Taylor, Roy Sturgill, Steve Waddle, Ying Li, Kentucky Transportation Center; Paul Goodrum, Keith Molenaar, Sara Al-Haddad, University of Colorado Boulder

Online Resource




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Surfactants for enhanced oil recovery applications Muhammad Sagir, Muhammad Mushtaq, M. Suleman Tahir, Muhammad Bilal Tahir, Abdul Ravoof Shaik

Online Resource




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Television at work: industrial media and American labor / Kit Hughes

Dewey Library - HD30.34.H74 2020




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ICTE in Transportation and Logistics 2019 Egils Ginters, Mario Arturo Ruiz Estrada, Miquel Angel Piera Eroles, editors

Online Resource




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Sharing mobilities: questioning our right to the city in the collaborative economy / Davide Arcidiacono and Mike Duggan

Rotch Library - HE305.A735 2020




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Structural failure: technical, legal and insurance aspects: proceedings of the founding symposium of the International Society for Technology, Law and Insurance, 18-19 November 1993, Vienna, Austria / edited by H.P. Rossmanith

Online Resource




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GIS-based simulation and analysis of intra-urban commuting / Yujie Hu, Fahui Wang

Rotch Library - HE305.H8 2019




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Bending the law of unintended consequences: a test-drive method for critical decision-making in organizations / Richard M. Adler

Online Resource




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Technical, technological and economical aspects of thin-seams coal mining: International Mining Forum 2007 / [edited by] Eugeniusz J. Sobczyk, Jerzy Kicki

Online Resource




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Sustainability management and business strategy in Asia / editors, Katsuhiko Kokubu, Yoshiyuki Nagasaka

Dewey Library - HD30.255.S869 2020




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Laparoscopic anatomy of the pelvic floor Jean-Bernard Dubuisson, Jean Dubuisson, Juan Puigventos

Online Resource




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Water-resisting property and key technologies of grouting reconstruction of the Upper Ordovician limestone in North China's coalfields Hao Wang

Online Resource




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Tubular structures XI: proceedings of the 11th International Symposium and IIW International Conference on Tubular Structures, Québec City, Canada, 31 August-2 September 2006 / editors, J.A. Packer & S. Willibald

Online Resource




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Sustainable procurement in supply chain operations / edited by Sachin K. Mangla, Sunil Luthra, Suresh Kumar Jakhar, Anil Kumar, Nripendra Rana

Online Resource




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What's your problem?: identifying and solving the five types of process problems / Kicab Castañeda-Méndez

Online Resource