id Enhancing the antimycobacterial efficacy of pyridine-4-carbohydrazide: linkage to additional antimicrobial agents via oxocarboxylic acids By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00663A, Research Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Václav Pflégr, Klára Konečná, Jiřina Stolaříková, Jan Ősterreicher, Ondřej Janďourek, Martin KrátkýLinking pyridine-4-carbohydrazide to other antimicrobial agents via oxocarboxylic acids significantly enhances efficacy against mycobacteria with promising selectivity and safety profiles.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
id Synthesis of cationic N-acylated thiazolidine for selective activity against Gram-positive bacteria and evaluation of N-acylation's role in membrane-disrupting activity By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00626G, Research ArticleAleena Pious, Vignesh Venkatasubramanian, Dharshini Karnan Singaravelu, Subburethinam Ramesh, Fuad Ameen, Anbazhagan VeerappanLipidation modulates the Gram-selective antibacterial activity of QPyNATh.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
id Generation and capture of naphthoquinonynes: a new frontier in the development of trypanocidal quinones via aryne chemistry By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00558A, Research ArticleLaura P. R. Figueroa, Renato L. de Carvalho, Renata G. Almeida, Esther R. S. Paz, Emilay B. T. Diogo, Maria H. Araujo, Warley S. Borges, Victor F. S. Ramos, Rubem F. S. Menna-Barreto, James M. Wood, John F. Bower, Eufrânio N. da Silva JúniorThis article presents A-ring functionalized quinones via a modern and efficient new strategy involving the generation and capture of benzyne quinones and their evaluation against Trypanosoma cruzi.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
id Light enhanced cytotoxicity and antitumoral effect of a ruthenium-based photosensitizer inspired from natural alkaloids By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00600C, Research Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Gennaro Sanità, Maria Laura Alfieri, Barbara Carrese, Serena Damian, Vincenza Mele, Gaetano Calì, Brigida Silvestri, Sebastiano Marra, Susan Mohammadi, Giuseppina Luciani, Paola Manini, Annalisa LambertiBiological assays carried out on melanoma and breast cancer cells highlighted the role of light in boosting the cytotoxic effect of a ruthenium complex featuring a dihydroisoquinoline ligand suggesting applications in photodynamic therapy.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
id A practical guide for the assay-dependent characterisation of irreversible inhibitors By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00707G, Review ArticleLavleen K. Mader, Jessica E. Borean, Jeffrey W. KeillorKinetic evaluations for assay dependent characterization of irreversible inhibitors.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
id U.S. Presidential polls: Thulasendrapuram residents pray for Kamala Harris ‘victory By www.thehindu.com Published On :: Tue, 05 Nov 2024 12:48:36 +0530 Full Article U.S. Elections
id Changes in train services notified due to demolition of old bridge near Tiruchi junction By www.thehindu.com Published On :: Tue, 05 Nov 2024 17:30:53 +0530 Full Article Tiruchirapalli
id Will decide on sharing stage with actor Vijay in consultation with VCK leaders: Thirumavalavan By www.thehindu.com Published On :: Tue, 05 Nov 2024 17:44:09 +0530 Mr. Thirumavalavan told reporters in Tiruchi that the book release event was not something that was planned recently, and that he had consented to take part in it almost a year ago Full Article Tamil Nadu
id Doctor assaulted inside Tiruchi ESI Hospital By www.thehindu.com Published On :: Tue, 05 Nov 2024 18:29:04 +0530 Full Article Tiruchirapalli
id Heavy weed growth at Kasi Viswanathar Temple tank prevents replenishing of underground water table, say Tiruchi residents By www.thehindu.com Published On :: Tue, 05 Nov 2024 21:04:51 +0530 Full Article Tiruchirapalli
id Deputy CM releases commemorative flag of Bharat Scouts and Guides By www.thehindu.com Published On :: Thu, 07 Nov 2024 17:48:40 +0530 Full Article Tiruchirapalli
id Farmers demand withdrawal of Tamil Nadu Land Consolidation Act By www.thehindu.com Published On :: Thu, 07 Nov 2024 17:59:18 +0530 The Coordination Committee of All Farmers’ Associations of Tamil Nadu says the State government has created a situation where industries can acquire fertile lands Full Article Tiruchirapalli
id Udhayanidhi lays foundation stone for infrastructure development projects in Thanjavur district By www.thehindu.com Published On :: Thu, 07 Nov 2024 18:48:04 +0530 Buildings at the Government Arts and Science College, Thirukkattupalli, construction of compound wall and an indoor stadium at the Government Rajah Serfoji College, Thanjavur, are among the projects Full Article Tiruchirapalli
id Bids invited for setting up International Dugong Conservation Centre at Manora By www.thehindu.com Published On :: Thu, 07 Nov 2024 19:03:19 +0530 The proposed centre, to be set up at an estimate of ₹41 crore, is being established to conserve endangered Dugong species and its habitat in the Palk Bay Full Article Tiruchirapalli
id NTK chief Seeman booked for alleged ‘derogatory remarks’ against Karunanidhi By www.thehindu.com Published On :: Fri, 08 Nov 2024 19:03:53 +0530 Full Article Tiruchirapalli
id Guidelines issued for fertilizer distribution in Karaikal for samba, thaladi paddy cultivation By www.thehindu.com Published On :: Fri, 08 Nov 2024 19:25:49 +0530 Full Article Tiruchirapalli
id Site identified for small-scale handloom park in Karur By www.thehindu.com Published On :: Sat, 09 Nov 2024 19:30:54 +0530 Full Article Tiruchirapalli
id 557: ChatGPT, Conferences, Fidgets on the Web, and Modern CSS in Real Life By shoptalkshow.com Published On :: Mon, 20 Mar 2023 07:01:51 +0000 When will AI be able to tell you the risk / reward of cleaning up trees? Are conferences back? Bringing fidgets to the web, internet as an anxiety machine, and Chris is working on talk on modern CSS in real life. Full Article All Episodes AI chatgpt Conferences CSS fidgets
id 559: Fidget Apps, Coding with AI, Dialog Element Navs, Getting Rid of CSS By shoptalkshow.com Published On :: Mon, 03 Apr 2023 07:14:35 +0000 Is there still any value in specializing in front-of-the-frontend dev? Would you ever use the dialog element for a mobile navigation? Why did CodePen decide to use Go for its GraphQL server? Full Article All Episodes chatgpt dialog Go
id 574: Estelle & Eric on CSS The Definitive Guide, 5th Edition By shoptalkshow.com Published On :: Mon, 17 Jul 2023 09:38:57 +0000 Estelle Weyl and Eric Meyer join us to talk about the 5th edition of their book, CSS: The Definitive Guide. We talk about some of CSS' biggest blunders, custom scroll bars, single line comments, shorthand in CSS, useless CSS trivia, and how to get started learning CSS in 2023. Full Article All Episodes CSS outline trivia
id 593: Beep & Texts, Tumblr, JavaScript & Web Components, & Cool Blog Post Ideas By shoptalkshow.com Published On :: Mon, 27 Nov 2023 09:00:10 +0000 Thoughts on smashing all communication messaging apps together, what's happened to Tumblr under Automattic, what the situation is with native web components and JavaScript, and looking at a list of types of blog posts. Full Article All Episodes communication Web Components
id 614: CSS Grid Level 3 aka Masonry with Adam Argyle By shoptalkshow.com Published On :: Mon, 06 May 2024 08:00:02 +0000 Adam Argyle stops by to chat about the conversation that's happening around CSS Grid / Masonry. What do we want? What might Apple's response to Google be? And nitpicking the spec just for fun. Full Article All Episodes CSS css grid masonry
id 629: The Great Divide, Global Design + Web Components, and Job Titles By shoptalkshow.com Published On :: Mon, 19 Aug 2024 08:01:48 +0000 A bit of follow-up on vibe driven development and JavaScript not causing The Great Divide, writing testing automation, global design systems and web components, could PHP be used for web components, what if view transitions are going to be everywhere, and frontend engineer vs design systems engineer job titles and descriptions. Full Article All Episodes design systems engineer PHP view transitions
id 631: Dave’s Second Brain Idea, Notion Thoughts, and Google’s LLM in Chrome By shoptalkshow.com Published On :: Mon, 02 Sep 2024 08:01:07 +0000 Dave's got an idea for a second brain app that's customized to his brain, where we're at with Notion and other notes apps, and accessibility on LLM's in browsers. Full Article All Episodes Chrome LLM notion second brain
id 635: Jeff Robbins and Visibox as an Instrument for Video By shoptalkshow.com Published On :: Mon, 30 Sep 2024 08:00:45 +0000 Jeff Robbins stops by to talk about his software, Visibox, that was used at Frostapalooza for presenting video at the concert, what it's like building an app with Electron, how it's distributed, how files are used and managed, and how he supports hardware devices inside Electron. Full Article All Episodes electron music Video Visibox
id Guidelines for green urbanisation By www.thehindu.com Published On :: Fri, 02 Oct 2015 21:12:45 +0530 The Ministry of Urban Development has proposed environmental guidelines for construction projects in urban areas. Nidhi Adlakha reports Full Article Property Plus
id Typecasting eco-ideas By www.thehindu.com Published On :: Fri, 20 Nov 2015 14:26:08 +0530 Important public buildings ignore the time-tested lessons of sustainability found in local architecture. By SATHYA PRAKASH VARANASHI Full Article Green Living
id Balrampur Chini hopes success of polylactic acid plant will be sweet By www.thehindubusinessline.com Published On :: Sun, 29 Sep 2024 20:46:00 +0530 In conversation with Avantika Saraogi, ED, and Stefan Barot, President, Chemicals Division, Balrampur Chini Mills Full Article Corporate File
id Idukki project leapfrogs ‘endangered’ list By www.thehindubusinessline.com Published On :: Sun, 13 Oct 2024 20:06:56 +0530 Local enthusiasts pitch in to bring amphibian species back from the brink of extinction Full Article Clean Tech
id How Ratan Tata pushed for evidence-led ayurveda By www.thehindubusinessline.com Published On :: Sun, 20 Oct 2024 20:38:00 +0530 Ratan Tata sought to promote research that could validate ayurveda through contemporary science Full Article Pulse
id Senior feline resident: Defib stays at his ambulance station By www.thehindubusinessline.com Published On :: Sun, 20 Oct 2024 21:19:43 +0530 Online petition halts re-homing of 16-year-old cat in London Full Article Pulse
id Nvidia: The lynchpin of the AI revolution By www.thehindubusinessline.com Published On :: Sat, 09 Nov 2024 18:18:47 +0530 The meteoric rise of the Santa Clara-headquartered chipmaker is powered by bold innovation Full Article Corporate File
id Trump presidency casts long shadow over climate summit By www.thehindubusinessline.com Published On :: Sun, 10 Nov 2024 19:27:32 +0530 The return of the climate denier as head of the world’s biggest greenhouse gas emitter threatens to throw net-zero negotiations into disarray once again Full Article Clean Tech
id HC tells jail authority to decide plea on lack of facilities for visiting lawyers By www.thehindu.com Published On :: Tue, 05 Nov 2024 01:10:55 +0530 Full Article Delhi
id Delhi riots case: HC dismisses plea by Khalid Saifi against attempt to murder charge By www.thehindu.com Published On :: Tue, 05 Nov 2024 13:00:21 +0530 Mr. Saifi submitted that once the offences under the Arms Act were dropped against him and neither any weapon was recovered nor the alleged gunshot was attributed to him, the charge of attempt to murder could not be framed Full Article Delhi
id Delhi HC dismisses plea by Khalid Saifi against attempt to murder charge By www.thehindu.com Published On :: Wed, 06 Nov 2024 01:19:07 +0530 Full Article Delhi
id Delhi cop Nidhin Valsan’s inspiring journey from arresting cancer to Ironman finish line By www.thehindu.com Published On :: Fri, 08 Nov 2024 02:05:22 +0530 Diagnosed with stage 4 non-Hodgkin’s lymphoma in 2021, IPS officer Nidhin Valsan resurrected himself by competing the Ironman triathlon and writing his memoir because he hopes to be a good influence on other cancer patients Full Article Delhi
id Issue of infiltration in Santhal Pargana was raised, Hemant did not listen: Champai Soren By www.thehindu.com Published On :: Fri, 08 Nov 2024 21:53:12 +0530 The longtime JMM-loyalist, who has now switched to the BJP, adds that decisions he had taken as CM — on tribal language education, PESA implementation, and jump-starting state recruitments — have been put on hold now Full Article Jharkhand Assembly
id Provide medical aid to jailed separatist leader Yasin Malik: Delhi HC to Tihar jail By www.thehindu.com Published On :: Sat, 09 Nov 2024 04:37:00 +0530 In his plea before the high court, Malik claimed to be a patient of “serious cardiac and kidney ailments”, currently facing a “life and death situation” Full Article Delhi
id Demonising Constitutional institutions pastime for some: Vice-President Jagdeep Dhankhar By www.thehindu.com Published On :: Sat, 09 Nov 2024 15:45:09 +0530 Addressing an event of an educational institution in New Delhi, the Vice-President said it is time to "bid adieu to this" Full Article India
id One dead, one injured in two firing incidents in Delhi within 10 minutes By www.thehindu.com Published On :: Sat, 09 Nov 2024 16:49:04 +0530 The two incidents of firing in northeast Delhi leave one dead and one injured; three suspects apprehended by police Full Article Delhi
id Security upped outside Canadian High Commission due to protest against temple attack By www.thehindu.com Published On :: Sun, 10 Nov 2024 16:13:43 +0530 The Hindu Sikh Global Forum members are marching towards the High Commission in the Chanakyapuri area Full Article Delhi
id ARRL Opening Late on Friday, Nov. 8 and Closed on Veterans Day, Nov. 11 By www.arrl.org Published On :: Thu, 07 Nov 2024 13:42:00 -0600 ARRL® The National Association for Amateur Radio® has two closures coming up for our headquarters in Newington, Connecticut:ARRL will be closed on Friday morning, November 8, 2024, for an employee meeting. During the short closure, members are encouraged to use the ARRL website, www.arrl.org, for membership renewals, publication purchases, and to access most benefits, services, and programs. T... Full Article
id In the corridors of power By www.thehindubusinessline.com Published On :: Sun, 08 Nov 2020 21:22:05 +0530 The author could have shed more light on the workings of power given his long stint in govt Full Article Books
id Cultural side to leadership By www.thehindubusinessline.com Published On :: Sun, 22 Nov 2020 21:12:47 +0530 Exploring the relevance of Indian-ness in our leaders Full Article Books
id Pranab’s Presidential years By www.thehindubusinessline.com Published On :: Sun, 10 Jan 2021 20:32:04 +0530 A matter-of-fact, yet reflective, memoir of a veteran politician Full Article Books
id Banking on the middle ground By www.thehindubusinessline.com Published On :: Sun, 17 Jan 2021 20:34:09 +0530 The book is long on analysis but short on solutions Full Article Opinion
id A kaleidoscopic memoir By www.thehindubusinessline.com Published On :: Sun, 20 Jun 2021 20:49:24 +0530 An anecdote filled book records a life well travelled Full Article Books
id How individuals shape institutions By www.thehindubusinessline.com Published On :: Sun, 04 Jul 2021 21:01:55 +0530 RK Talwar, SBI’s legendary Chairman, inspired an entire generation of bankers Full Article Books
id A memoir which leaves a lot unsaid By www.thehindubusinessline.com Published On :: Sun, 22 Aug 2021 20:50:55 +0530 Amartya Sen’s book does not focus enough on his towering academic and professional life Full Article Books