The fly-half has not appeared for Leinster since the turn of the year, and was ruled out of last Saturday’s Champions Cup quarter-final victory over Ulster with a quad issue.

Ireland and Ulster captain Rory Best has announced he will retire from professional rugby after the World Cup in Japan. Hooker Best has been capped 116 times by his country.

Leinster flanker Sean O'Brien is preparing for an emotional farewell after next week's Champions Cup final - having revealed that he would have stayed in Dublin for a quarter of the money.

The outgoing Wales coach was named head coach for the 2021 tour of South Africa on Friday, having already led the Lions to victory in Australia and a drawn series in New Zealand last time out.

Joe Schmidt has suffered a World Cup injury blow with veteran flanker Seán O'Brien ruled out of the tournament in Japan with a hip injury. His set for six months on the sidelines.

Munster duo Mike Haley and Jean Kleyn are the only uncapped players included in Ireland's 44-man training squad for their pre-World Cup training camps.

Catt is expected to join Ireland as attack coach after the autumn's Rugby World Cup. The former England coach has agreed a deal to trade Italy for Ireland's set-up, it is understand.

Premier playmaker Johnny Sexton is expected to be fit shortly, but Ireland can ill afford to lose either of their main backline pivots. They open their World Cup by taking on Scotland on September 22.

England want all three available to take on Ireland to offset any need to pitch Billy Vunipola into a third Test in as many weeks. All three trained on Wednesday at England's Pennyhill Park camp.

Johnny Sexton has missed out on Ireland's World Cup warm-up clash with England at Twickenham on Saturday. The fly-half sat out of training at the start of the week in Portugal.

England have reverted to the 10-12 alliance of George Ford and captain Owen Farrell for Saturday's clash against Ireland at Twickenham, in a line-up featuring nine changes.

SIR CLIVE WOODWARD: It is exactly the team I would have picked for a must-win game at the tournament. This is the first time he has put his full strength side out in these warm-up games.

CHRIS FOY AT TWICKENHAM: The match tickets proclaimed 'this is no warm-up' and on a scorching, record-breaking day here, Manu Tuilagi and England proved too hot to handle.

Just 100 days to go until 2019 Rugby World Cup in Japan now. Sportsmail provide you with all you need to know for Japan RWC including pool fixtures, date, KO time and channel.

Ireland and Wales will smash into each other in the final World Cup warm-up of the summer, despite the lingering risk of cruel last-minute injuries. Both sides are almost at full strength for Dublin Test.

Warren Gatland insisted that Rhys Patchell would travel to the World Cup on Wednesday despite suffering a worrying concussion in Wales' defeat to Ireland.

Fly-half Rhys Patchell will be assessed ahead of Wales' World Cup departure on Wednesday after he was concussed during their final warm-up game.

RORY KEANE: This Ireland squad were primed to reach a first-ever World Cup semi-final, and possibly more. But they have been seemingly in free-fall since the events of February 2 at the Aviva.

World Rugby bosses have hit back at claims 31-man World Cup squads threaten player welfare by insisting top coaches left their objections too late to have any effect for the 2019 tournament in Japan.

SCRUM'S THE WORD WORLD CUP DIARY: Rhys Carre, Wales fiery-haired loose-head prop, has one extra item in his bag - the 'Love Spoon'.

Over a long and distinguished career, Brian O'Driscoll became adept at dealing with everything and anything thrown his way.

Sportsmail provide a breakdown of how points are won and lost during the Rugby World Cup as 20 teams look reach the final in Japan and how teams can obtain the bonus points in Japan.

Our first home nation clash of the Rugby World Cup  and hopefully not last will see Ireland take on Scotland in their pool A clash. Follow live score, substitutions, sin bins and more right here.

Ireland delivered on their promise to hit form when it mattered most by stunning Scotland 27-3 with a bonus-point blitz to launch their Japanese World Cup quest in style.

Gregor Townsend confessed it 'doesn't look good' for Hamish Watson after admitting the Scotland flanker's World Cup might be over already. The Dark Blues suffered a 27-3 mauling from Ireland.

RORY KEANE IN YOKOHAMA: Iain Henderson hailed the performance of Rory Best after Ireland trounced Scotland, claiming the captain had 'silenced a lot of his critics'.

RORY KEANE IN SHIZUOKA: Carty starts only his second Test in place of conductor-in-chief Johnny Sexton, who is out with a groin injury. Schmidt reckons Carty has the right stuff.

Japan claimed one of the greatest upsets in rugby history, four years after their historic win over South Africa. 

Ireland head coach Joe Schmidt admitted Japan had raised their game to 'furious' levels after stunning them 19-12 in Shizuoka.

Brian O'Driscoll praised Japan and poured scorn on Ireland's performance after the Brave Blossoms produced a stunning World Cup upset. 

RORY KEANE IN SHIZUOKA: Japan shocked the globe for the second time in four years by stunning Ireland 19-12 to light a bomb under Pool A and a fire under their home World Cup.

RORY KEANE IN SHIZUOKA: Johnny Sexton has challenged Ireland to channel the hurt of the loss to Japan into their final pool games with Russia and Samoa. 

With prop Demba Bamba out with a thigh problem, France announced on social media that Uini Atonio (below) would replace him. But they deleted the tweet after discovering he was injured.

Ireland coach Joe Schmidt has revealed World Rugby admitted there were three incorrect offside calls given against his side during their shock 19-12 World Cup Pool A defeat by Japan.

Ireland picked up the bonus point they needed but were made to work hard for it by a stubborn Russian side. Russia spent 20 minutes down to 14 men in the middle of the match.

Sportsmail provide you with everything you need to know for Rugby World Cup 2019 including pool fixtures, channel and results in Japan.

Sexton captained Ireland for the first time on Thursday, but he was replaced by Jack Carty for the second-half of his side's five-try win over the Bears.

RORY KEANE AT THE MISAKI PARK STADIUM: Job done. Ireland got their World Cup campaign back on a track with a bonus-point win over Russia in Kobe, but this was another worrying performance.

RORY KEANE IN KOBE: There was a moment in the second half which pretty much summed up Ireland's performance under the closed roof here at Kobe Misaki Stadium.

RORY KEANE IN FUKUOKA: Fourteen-man Ireland sealed their place in the World Cup quarter finals with a seven-try victory over Samoa here in Fukuoka, but Bundee Aki's red card will be a worry.

Bundee Aki was sent off in the 29th minute after a high tackle at Fukuoka Hakatanomori Stadium and faces a multiple-game suspension, souring the win that put Ireland through to the quarters.

Tadhg Furlong has warned that to switch off even for a second against New Zealand will cost Ireland the chance of a maiden World Cup semi-final.

SIR CLIVE WOODWARD: This game will be massive. So far in Anglo-Australian encounters at World Cups we have one victory apiece in the final, two England quarter-final wins and two Aussie pool wins.

Johnny Sexton has questioned the 'strange' negativity around Ireland's World Cup campaign, insisting Joe Schmidt's men are ready to peak for the All Blacks.

Bundee Aki will miss the rest of the World Cup after receiving a three-match ban for his red card against Samoa. The Ireland centre was sent off in the 47-5 win for a high tackle on UJ Seuteni.

WORLD CUP DIARY: Johnny Sexton was as combative off the field as he is on it on Monday, questioning the media coverage of Ireland's World Cup.

All Blacks boss Steve Hansen lit the fuse on a potentially explosive week on Monday by vowing to lay false traps for Ireland's master tactician and head coach Joe Schmidt.

'Sean aggravated a pre-existing neck muscle complaint and has been ruled out of the remainder of RWC19,' read an Irish Rugby Football Union statement.

NIK SIMON IN TOKYO: Hansen owns a share of Nature Strip, who will run in the $14million sprint race in Sydney. Coach is focused on the All Blacks' quest for a third straight World Cup title.

The Rugby World Cup kicked off four weeks ago today and now, via 50 pool stage matches, we are down to eight teams. Sportsmail tells you all need to know about the quarter-finals.