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Ultra-efficient delivery of CRISPR/Cas9 using ionic liquid conjugated polymers for genome editing-based tumor therapy

Biomater. Sci., 2024, 12,1716-1725
DOI: 10.1039/D3BM01981K, Paper
Zhongming Huang, Tongren Yang, Jie Yu, Yijian Gao, Yuhua Weng, Yuanyu Huang, Shengliang Li
Through molecular screening, ionic liquid-conjugated polymers (IL-CPs) are developed for highly efficient delivery of CRISPR/Cas9 system, which demonstrated high-performance genome editing-based tumor therapy.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Applications of peptide-based nanomaterials in targeting cancer therapy

Biomater. Sci., 2024, 12,1630-1642
DOI: 10.1039/D3BM02026F, Review Article
Beilei Sun, Limin Zhang, Mengzhen Li, Xin Wang, Weizhi Wang
To meet the precise diagnosis and treatment as well as reduce systemic toxicity and side effects, self-assembled peptides are applied to the targeting therapy, including targeting theranostics, nanocarrier delivery, immunotherapy, and combination therapy.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Optimization of hair follicle spheroids for hair-on-a-chip

Biomater. Sci., 2024, 12,1693-1706
DOI: 10.1039/D3BM02012F, Paper
Subin Jeong, Hyeon-Min Nam, Gun Yong Sung
We report spheroids prepared by injecting LEF1 and Wnt1 into DPCs via transfection and then adding KCs and HUVECs. Through SEM, we observed a part extending outward from the TK and TKH surfaces, as indicated by white arrows.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Comparative analysis of supercritical fluid-based and chemical-based decellularization techniques for nerve tissue regeneration

Biomater. Sci., 2024, 12,1847-1863
DOI: 10.1039/D3BM02072J, Paper
Open Access
Beom-Seok Kim, Jeong-Uk Kim, Jae Woo Lee, Kyung Min Ryu, Rachel H. Koh, Kyoung-Ha So, Nathaniel S. Hwang
The supercritical (SC) fluid-based method were utilized for nerve tissue decellualrization. In vitrovivo assessments underscore its potential for advanced tissue engineering and regenerative applications.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Bi-functional quercetin/copper nanoparticles integrating bactericidal and anti-quorum sensing properties for preventing the formation of biofilms

Biomater. Sci., 2024, 12,1788-1800
DOI: 10.1039/D4BM00034J, Paper
Jingjing Cheng, Haixin Zhang, Kunyan Lu, Yi Zou, Dongxu Jia, Hong Yang, Hong Chen, Yanxia Zhang, Qian Yu
A bi-functional antibiofilm nanoplatform was developed based on a complex of quercetin and copper integrating bactericidal and anti-quorum sensing properties.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Futuristic Alzheimer's therapy: acoustic-stimulated piezoelectric nanospheres for amyloid reduction

Biomater. Sci., 2024, 12,1801-1821
DOI: 10.1039/D3BM01688A, Paper
Manju Sharma, Samraggi Choudhury, Anand Babu, Varun Gupta, Dipanjan Sengupta, Syed Afroz Ali, Mrunali D. Dhokne, Ashok Kumar Datusalia, Dipankar Mandal, Jiban Jyoti Panda
The graphical abstract portraying the utility of peizoactive polydopamine-coated PVDF nanospheres as potential therapeutic modalities for Alzheimer's disease. The nanospheres induced fibril disaggregation and neuroprotection upon acoustic activation in neural cells and animal model.
The content of this RSS Feed (c) The Royal Society of Chemistry




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N-Halaminated spermidine-containing polymeric coating enables titanium to achieve dual functions of antibacterial and osseointegration

Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM00061G, Paper
Hang Ren, Peng Wang, Hanwen Huang, Junshen Huang, Yuheng Lu, Yanfeng Wu, Zhongyu Xie, Youchen Tang, Zhaopeng Cai, Huiyong Shen
Modified Ti with a porous N-halaminated spermidine-containing polymeric coating is constructed, and it has both excellent antibacterial and osteogenic abilities to enhance osseointegration, making it potentially applicable in orthopedics.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Bioinspired ginsenoside Rg3 PLGA nanoparticles coated with tumor-derived microvesicles to improve chemotherapy efficacy and alleviate toxicity

Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM00159A, Paper
Shulei Zhang, Bo Zheng, Yiqi Wei, Yuhao Liu, Lan Yang, Yujiao Qiu, Jing Su, Mingfeng Qiu
Breast cancer, a pervasive malignancy affecting women, demands a diverse treatment approach including chemotherapy, radiotherapy, and surgical interventions.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Bioactivity of cerium dioxide nanoparticles as a function of size and surface features

Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D3BM01900D, Paper
Veronika Sarnatskaya, Yuliia Shlapa, Denis Kolesnik, Olexandra Lykhova, Dmytro Klymchuk, Serhii Solopan, Svitlana Lyubchyk, Iuliia Golovynska, Junle Qu, Yurii Stepanov, Anatolii Belous
Nano-dispersed cerium dioxide is promising for use in medicine due to its unique physicochemical properties, low toxicity, the safety of in vivo usage, active participation in different redox processes occurring in living cells, and its regenerative potential.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Correction: Hybrid protein microspheres and their responsive release behaviors and inhibitory effects on melanin synthesis

Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM90029D, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Ee Taek Hwang, Yeahwa Yoon, Ka Ram Kim, Chan Hee Lee, Kyung Chan Jeon, Ji Ho Min, Jae Won Lee, Jangyong Kim
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Correction: Clodronate-nintedanib-loaded exosome–liposome hybridization enhances the liver fibrosis therapy by inhibiting Kupffer cell activity

Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM90028F, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Keqin Ji, Mingrui Fan, Dong Huang, Lingna Sun, Bingqin Li, Ruoting Xu, Jiajing Zhang, Xuan Shao, Yanzuo Chen
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Macrophage membrane-camouflaged nanoclusters of ultrasmall iron oxide nanoparticles for precision glioma theranostics

Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM00357H, Paper
Bin Zhang, Rui Yang, Hongwei Yu, Yamin Peng, Haoyu Huang, Meera Moydeen Abdul Hameed, Han Wang, Guixiang Zhang, Mohamed EL-Newehy, Mingwu Shen, Xiangyang Shi, Shaojun Peng
Macrophage membrane-camouflaged nanoclusters of ultrasmall iron oxide nanoparticles can be developed to cross the blood–brain barrier for magnetic resonance imaging and chemo/chemodynamic therapy.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Comparison study of surface-initiated hydrogel coatings with distinct side-chains for improving biocompatibility of polymeric heart valves

Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM00158C, Paper
Yiduo Chen, Yirong Guo, Xinyi Li, Yanchen Chen, Jiarong Wang, Honglin Qian, Jing Wang, Youxiang Wang, Xinyang Hu, Jian'an Wang, Jian Ji
Three surface-initiated hydrogel coatings (pMPC, pAMPS, pHEMA) are constructed on polymeric heart valves. The zwitterionic pMPC coating displays optimal performances, including durable anti-coagulation, anti-inflammation, and anti-calcification.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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PET image-guided kidney injury theranostics enabled by a bipyramidal DNA framework

Biomater. Sci., 2024, 12,2086-2095
DOI: 10.1039/D3BM01575K, Paper
Open Access
Pinghui Li, Zhidie Huang, Xiaoyan Duan, Tao Wang, Shaowen Yang, Dawei Jiang, Jianbo Li
We constructed 68Ga-BDF and employed PET imaging to establish its pharmacokinetic model. BDF was eliminated from the body via the urinary system. We observed distinct imaging indicators in UUO and AKI mouse models. Furthermore, we observed the therapeutic effect of BDF on AKI.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Liquid–liquid phase separation-inspired design of biomaterials

Biomater. Sci., 2024, 12,1943-1949
DOI: 10.1039/D3BM02008H, Minireview
Yang Song
Biological liquid–liquid phase separation (LLPS) provides novel insights for the assembly of biomaterials with tailored structure and intrinsic functionality.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Engineering sulfated polysaccharides and silk fibroin based injectable IPN hydrogels with stiffening and growth factor presentation abilities for cartilage tissue engineering

Biomater. Sci., 2024, 12,2067-2085
DOI: 10.1039/D3BM01466E, Paper
Akansha Dixit, Aman Mahajan, Rakshita Saxena, Saptomee Chakraborty, Dhirendra S. Katti
In this study, we combined the β-sheet mediated self-stiffening ability of silk with growth factor presenting ability of sulphated carboxymethyl cellulose in an injectable interpenetrating network hydrogel for repair of articular cartilage defects.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Enhancing antioxidant properties of CeO2 nanoparticles with Nd3+ doping: structural, biological, and machine learning insights

Biomater. Sci., 2024, 12,2108-2120
DOI: 10.1039/D3BM02107F, Paper
Oscar Ceballos-Sanchez, Diego E. Navarro-López, Jorge L. Mejía-Méndez, Gildardo Sanchez-Ante, Vicente Rodríguez-González, Angélica Lizeth Sánchez-López, Araceli Sanchez-Martinez, Sergio M. Duron-Torres, Karla Juarez-Moreno, Naveen Tiwari, Edgar R. López-Mena
The antioxidant capabilities of nanoparticles are contingent upon various factors, including their shape, size, and chemical composition.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Optimization of lipid assisted polymeric nanoparticles for siRNA delivery and cancer immunotherapy

Biomater. Sci., 2024, 12,2057-2066
DOI: 10.1039/D3BM02071A, Paper
Song Lin, Houjin Jing, Xiaojiao Du, Xianzhu Yang, Jun Wang
A siRNA delivery system was developed using clinically approved mPEG-b-PLGA, cationic lipid and ionizable lipid for siRNA delivery and cancer immunotherapy.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Correction: A Y1 receptor ligand synergized with a P-glycoprotein inhibitor improves the therapeutic efficacy of multidrug resistant breast cancer

Biomater. Sci., 2024, 12,2165-2166
DOI: 10.1039/D4BM90022G, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Yinjie Wang, Zhenqi Jiang, Bo Yuan, Yuchen Tian, Lingchao Xiang, Yanying Li, Yong Yang, Juan Li, Aiguo Wu
The content of this RSS Feed (c) The Royal Society of Chemistry




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Cell-membrane engineering strategies for clinic-guided design of nanomedicine

Biomater. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D3BM02114A, Review Article
Di Huang, Xiaoyu Wang, Wentao Wang, Jiachen Li, Xiaomei Zhang, Bing Xia
Cells are the fundamental units of life. The cell membrane primarily composed of two layers of phospholipids (a bilayer) structurally defines the boundary of a cell, which can protect its...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Lipid sulfoxide polymers as potential inhalable drug delivery platforms with differential albumin binding affinity

Biomater. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D3BM02020G, Paper
Gayathri Ediriweera, Neville Butcher, Ashok Kothapalli, Jiacheng Zhao, Joanne Therese Blanchfield, Christopher N. Subasic, James Lynden Grace, Changkui Fu, Xiao Tan, John F. Quinn, David Ascher, Michael R Whittaker, Andrew Whittaker, Lisa Kaminskas
Inhalable nanomedicines are increasingly being developed to optimise the pharmaceutical treatment of respiratory diseases. Large lipid-based nanosystems at the forefront of the inhalable nanomedicines development pipeline, though, have a number...
The content of this RSS Feed (c) The Royal Society of Chemistry




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An injectable fluorescent and iodinated hydrogel for preoperative localization and dual image-guided surgery of pulmonary nodules

Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM00035H, Paper
Open Access
Woojin Back, Jiyun Rho, Kyungsu Kim, Hwan Seok Yong, Ok Hwa Jeon, Byeong Hyeon Choi, Hyun Koo Kim, Ji-Ho Park
We report the development of an injectable hydrogel-based dual computed tomography (CT) and near-infrared (NIR) imaging marker for use in preoperative pulmonary localization and intraoperative dual-imaging of deep-seated nodules.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Reply To: How to add custom widgets?

I am trying to say yo just add some step , i hope you can add custom widgets
Create your widget’s class by extending the standard WP_Widget class and some of its functions.
Register your widget so that it’s made available in the Widgets screen.
Make sure that your theme has at least one widget area in which to add the widgets.




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Blogging for Kids

Children love having an audience. The instant recognition and approval that comes from a crowd just can't be beat. Employing blogs to help develop good spelling habits, grammar skills, and develop a love for writing at a young age is an innovative concept that has potential.




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Blog Post Ideas

The best blogs and feeds are those that contain unique, fresh, compelling, content. So where do these prolific posters get their ideas? I talked to a handful of bloggers to determine where their inspiration originated for their content.

Not surprisingly, ideas for blog posts or RSS feed items originate or are influenced by other web content. The following are venues for finding your online muse:

Blog Post Ideas




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RSS Guidelines

In general, the following are guidelines for constructing an RSS feed. It is good to get into the habit of validating the RSS feed, either with software, or with an online validator.

Here are some general guidelines for creating RSS Feeds




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Real Estate Video Podcast Tips

The use of technology can define the success or failure of a business. This is no more evident than in the real estate industry. Realtors who flocked to the latest technologies, adopted them, and applied them in order to enhance and sell property, are still prospering.

Real Estate Video Podcast




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Tips to Optimize Video Podcasts

It does not matter what you call them: vodcasts, vidcasts, videocasting, or video podcasting... there are a few behind-the-scenes actions you can take to help attract more attention to your video productions. Just like websites, it does not matter how amazing the content is if interested people are unable to find it.

Use the following suggestions to help increase the exposure your videos receive... Tips to Optimize Video Podcasts.




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Google announces new Android features at MWC 2024

The focus is on easier AI-assisted communication




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Motorola Edge 50 Pro review. A marvellous mid-ranger?

The comeback king of smartphones has thrown in an affordable option like no other




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A shapeshifting sidekick! ASUS Zenbook Duo (2024)

The dual screen delight is back and updated to offer even more!




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Honey, can you ‘watch’ the kids?

With child-friendly functions activated, this could be the first collaborative gadget for your family




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Moto Edge 50 review: A mid-ranger, with high-end ambitions

The Moto Edge 50 is one of those appealing options aimed at the mid-range market, and here’s how it fares.




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Why finance and accounting students should consider the US CMA certification

The US CMA certification offers both upskilling opportunities and professional relevance at national and international levels




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Provide more time to submit options for higher PF pension: CITU




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A beginner’s guide to a career in aviation

The aviation sector offers a plethora of jobs across marketing, hospitality, engineering, and operations




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Post COVID-19, corporates begin offering OPD benefits to employees

Of the 251 IT, manufacturing, pharma, engineering, financial and other companies studied, only 40 were providing out-patient department (OPD) benefits in 2019, per the latest report by AON India




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Paid internships for trans persons on the increase

To translate these opportunities into jobs more ground needs to be covered




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Aca Sports Counselling in Hyderabad integrates sports and academics, providing personalised guidance to athletes

Padmavathi Devarakonda’s Aca Sports Counselling in Hyderabad blends the spirit of sports with academic guidance to help aspiring athletes achieve their dreams




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NCLAT accepts settlement proposal between Byju’s and BCCI, sets aside insolvency order

The appellate tribunal also dismissed the allegation of round-tripping levelled by Byju's U.S.-based lenders, saying they failed to provide any evidence for the same




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What’s behind the widening gender wage gap in the US?

The first widening of the gender wage in 20 years is the latest indication that many women have paid a price for leaving the workforce at the height of the COVID-19 pandemic, either because they lost their jobs or because they quit because of caretaking responsibilities




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HR conclave provides a primer on DEI




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Vizianagaram district MLC election: TDP, YSRCP high commands hold crucial meeting on selection of candidates

Though YSRCP has absolute majority in local bodies, the TDP indicated that it would field the candidate in the election




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Andhra Pradesh government constitutes State Investment Promotion Board with CM Chandrababu Naidu as head

The SIPB will meet at regular intervals to examine all proposals related to industrial and infrastructure investments and take appropriate decisions for early realisation of investments in Andhra Pradesh




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B.R. Naidu to take charge as TTD Chairman on November 6

He offers prayers at Sri Padmavathi Ammavari temple in Tiruchanur




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TTD chairman B.R. Naidu vows to protect sanctity of Tirumala temple




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Resident associations in Visakhapatnam urge State govt. to revoke levying of true-up charges

The announcement to levy the additional charges is surprising, given the NDA govt.’s pre-poll assurance that electricity rates would not be hiked, say association leaders




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Usha Chilukuri Vance’s grandaunt in the spotlight after J.D. Vance becomes U.S. Vice President-elect

The wife of J.D. Vance, who was elected Vice-President as running mate of President-elect Donald Trump, has a connection with Visakhapatnam; the coastal city is home to Usha’s paternal grandaunt Chilukuri Santhamma, 96, a professor of physics




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Call to bridge the gap between the youth and elderly




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Andhra CM Chandrabu Naidu to virtually lay stone for 220KV sub-station in Anakapalli district