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New Zealand says it backs Taiwan's role in WHO due to success with coronavirus




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The McMichaels can't be charged with a hate crime by the state in the shooting death of Ahmaud Arbery because the law doesn't exist in Georgia

Georgia is one of four states that doesn't have a hate crime law. Arbery's killing has reignited calls for legislation.





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Nearly one-third of Americans believe a coronavirus vaccine exists and is being withheld, survey finds

The Democracy Fund + UCLA Nationscape Project found some misinformation about the coronavirus is more widespread that you might think.





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Bayesian Quantile Regression with Mixed Discrete and Nonignorable Missing Covariates

Zhi-Qiang Wang, Nian-Sheng Tang.

Source: Bayesian Analysis, Volume 15, Number 2, 579--604.

Abstract:
Bayesian inference on quantile regression (QR) model with mixed discrete and non-ignorable missing covariates is conducted by reformulating QR model as a hierarchical structure model. A probit regression model is adopted to specify missing covariate mechanism. A hybrid algorithm combining the Gibbs sampler and the Metropolis-Hastings algorithm is developed to simultaneously produce Bayesian estimates of unknown parameters and latent variables as well as their corresponding standard errors. Bayesian variable selection method is proposed to recognize significant covariates. A Bayesian local influence procedure is presented to assess the effect of minor perturbations to the data, priors and sampling distributions on posterior quantities of interest. Several simulation studies and an example are presented to illustrate the proposed methodologies.




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Bayesian Sparse Multivariate Regression with Asymmetric Nonlocal Priors for Microbiome Data Analysis

Kurtis Shuler, Marilou Sison-Mangus, Juhee Lee.

Source: Bayesian Analysis, Volume 15, Number 2, 559--578.

Abstract:
We propose a Bayesian sparse multivariate regression method to model the relationship between microbe abundance and environmental factors for microbiome data. We model abundance counts of operational taxonomic units (OTUs) with a negative binomial distribution and relate covariates to the counts through regression. Extending conventional nonlocal priors, we construct asymmetric nonlocal priors for regression coefficients to efficiently identify relevant covariates and their effect directions. We build a hierarchical model to facilitate pooling of information across OTUs that produces parsimonious results with improved accuracy. We present simulation studies that compare variable selection performance under the proposed model to those under Bayesian sparse regression models with asymmetric and symmetric local priors and two frequentist models. The simulations show the proposed model identifies important covariates and yields coefficient estimates with favorable accuracy compared with the alternatives. The proposed model is applied to analyze an ocean microbiome dataset collected over time to study the association of harmful algal bloom conditions with microbial communities.




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Additive Multivariate Gaussian Processes for Joint Species Distribution Modeling with Heterogeneous Data

Jarno Vanhatalo, Marcelo Hartmann, Lari Veneranta.

Source: Bayesian Analysis, Volume 15, Number 2, 415--447.

Abstract:
Species distribution models (SDM) are a key tool in ecology, conservation and management of natural resources. Two key components of the state-of-the-art SDMs are the description for species distribution response along environmental covariates and the spatial random effect that captures deviations from the distribution patterns explained by environmental covariates. Joint species distribution models (JSDMs) additionally include interspecific correlations which have been shown to improve their descriptive and predictive performance compared to single species models. However, current JSDMs are restricted to hierarchical generalized linear modeling framework. Their limitation is that parametric models have trouble in explaining changes in abundance due, for example, highly non-linear physical tolerance limits which is particularly important when predicting species distribution in new areas or under scenarios of environmental change. On the other hand, semi-parametric response functions have been shown to improve the predictive performance of SDMs in these tasks in single species models. Here, we propose JSDMs where the responses to environmental covariates are modeled with additive multivariate Gaussian processes coded as linear models of coregionalization. These allow inference for wide range of functional forms and interspecific correlations between the responses. We propose also an efficient approach for inference with Laplace approximation and parameterization of the interspecific covariance matrices on the Euclidean space. We demonstrate the benefits of our model with two small scale examples and one real world case study. We use cross-validation to compare the proposed model to analogous semi-parametric single species models and parametric single and joint species models in interpolation and extrapolation tasks. The proposed model outperforms the alternative models in all cases. We also show that the proposed model can be seen as an extension of the current state-of-the-art JSDMs to semi-parametric models.




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A Novel Algorithmic Approach to Bayesian Logic Regression (with Discussion)

Aliaksandr Hubin, Geir Storvik, Florian Frommlet.

Source: Bayesian Analysis, Volume 15, Number 1, 263--333.

Abstract:
Logic regression was developed more than a decade ago as a tool to construct predictors from Boolean combinations of binary covariates. It has been mainly used to model epistatic effects in genetic association studies, which is very appealing due to the intuitive interpretation of logic expressions to describe the interaction between genetic variations. Nevertheless logic regression has (partly due to computational challenges) remained less well known than other approaches to epistatic association mapping. Here we will adapt an advanced evolutionary algorithm called GMJMCMC (Genetically modified Mode Jumping Markov Chain Monte Carlo) to perform Bayesian model selection in the space of logic regression models. After describing the algorithmic details of GMJMCMC we perform a comprehensive simulation study that illustrates its performance given logic regression terms of various complexity. Specifically GMJMCMC is shown to be able to identify three-way and even four-way interactions with relatively large power, a level of complexity which has not been achieved by previous implementations of logic regression. We apply GMJMCMC to reanalyze QTL (quantitative trait locus) mapping data for Recombinant Inbred Lines in Arabidopsis thaliana and from a backcross population in Drosophila where we identify several interesting epistatic effects. The method is implemented in an R package which is available on github.




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Learning Semiparametric Regression with Missing Covariates Using Gaussian Process Models

Abhishek Bishoyi, Xiaojing Wang, Dipak K. Dey.

Source: Bayesian Analysis, Volume 15, Number 1, 215--239.

Abstract:
Missing data often appear as a practical problem while applying classical models in the statistical analysis. In this paper, we consider a semiparametric regression model in the presence of missing covariates for nonparametric components under a Bayesian framework. As it is known that Gaussian processes are a popular tool in nonparametric regression because of their flexibility and the fact that much of the ensuing computation is parametric Gaussian computation. However, in the absence of covariates, the most frequently used covariance functions of a Gaussian process will not be well defined. We propose an imputation method to solve this issue and perform our analysis using Bayesian inference, where we specify the objective priors on the parameters of Gaussian process models. Several simulations are conducted to illustrate effectiveness of our proposed method and further, our method is exemplified via two real datasets, one through Langmuir equation, commonly used in pharmacokinetic models, and another through Auto-mpg data taken from the StatLib library.




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Adaptive Bayesian Nonparametric Regression Using a Kernel Mixture of Polynomials with Application to Partial Linear Models

Fangzheng Xie, Yanxun Xu.

Source: Bayesian Analysis, Volume 15, Number 1, 159--186.

Abstract:
We propose a kernel mixture of polynomials prior for Bayesian nonparametric regression. The regression function is modeled by local averages of polynomials with kernel mixture weights. We obtain the minimax-optimal contraction rate of the full posterior distribution up to a logarithmic factor by estimating metric entropies of certain function classes. Under the assumption that the degree of the polynomials is larger than the unknown smoothness level of the true function, the posterior contraction behavior can adapt to this smoothness level provided an upper bound is known. We also provide a frequentist sieve maximum likelihood estimator with a near-optimal convergence rate. We further investigate the application of the kernel mixture of polynomials to partial linear models and obtain both the near-optimal rate of contraction for the nonparametric component and the Bernstein-von Mises limit (i.e., asymptotic normality) of the parametric component. The proposed method is illustrated with numerical examples and shows superior performance in terms of computational efficiency, accuracy, and uncertainty quantification compared to the local polynomial regression, DiceKriging, and the robust Gaussian stochastic process.




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Bayesian Estimation Under Informative Sampling with Unattenuated Dependence

Matthew R. Williams, Terrance D. Savitsky.

Source: Bayesian Analysis, Volume 15, Number 1, 57--77.

Abstract:
An informative sampling design leads to unit inclusion probabilities that are correlated with the response variable of interest. However, multistage sampling designs may also induce higher order dependencies, which are ignored in the literature when establishing consistency of estimators for survey data under a condition requiring asymptotic independence among the unit inclusion probabilities. This paper constructs new theoretical conditions that guarantee that the pseudo-posterior, which uses sampling weights based on first order inclusion probabilities to exponentiate the likelihood, is consistent not only for survey designs which have asymptotic factorization, but also for survey designs that induce residual or unattenuated dependence among sampled units. The use of the survey-weighted pseudo-posterior, together with our relaxed requirements for the survey design, establish a wide variety of analysis models that can be applied to a broad class of survey data sets. Using the complex sampling design of the National Survey on Drug Use and Health, we demonstrate our new theoretical result on multistage designs characterized by a cluster sampling step that expresses within-cluster dependence. We explore the impact of multistage designs and order based sampling.




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Latent Nested Nonparametric Priors (with Discussion)

Federico Camerlenghi, David B. Dunson, Antonio Lijoi, Igor Prünster, Abel Rodríguez.

Source: Bayesian Analysis, Volume 14, Number 4, 1303--1356.

Abstract:
Discrete random structures are important tools in Bayesian nonparametrics and the resulting models have proven effective in density estimation, clustering, topic modeling and prediction, among others. In this paper, we consider nested processes and study the dependence structures they induce. Dependence ranges between homogeneity, corresponding to full exchangeability, and maximum heterogeneity, corresponding to (unconditional) independence across samples. The popular nested Dirichlet process is shown to degenerate to the fully exchangeable case when there are ties across samples at the observed or latent level. To overcome this drawback, inherent to nesting general discrete random measures, we introduce a novel class of latent nested processes. These are obtained by adding common and group-specific completely random measures and, then, normalizing to yield dependent random probability measures. We provide results on the partition distributions induced by latent nested processes, and develop a Markov Chain Monte Carlo sampler for Bayesian inferences. A test for distributional homogeneity across groups is obtained as a by-product. The results and their inferential implications are showcased on synthetic and real data.




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Estimating the Use of Public Lands: Integrated Modeling of Open Populations with Convolution Likelihood Ecological Abundance Regression

Lutz F. Gruber, Erica F. Stuber, Lyndsie S. Wszola, Joseph J. Fontaine.

Source: Bayesian Analysis, Volume 14, Number 4, 1173--1199.

Abstract:
We present an integrated open population model where the population dynamics are defined by a differential equation, and the related statistical model utilizes a Poisson binomial convolution likelihood. Key advantages of the proposed approach over existing open population models include the flexibility to predict related, but unobserved quantities such as total immigration or emigration over a specified time period, and more computationally efficient posterior simulation by elimination of the need to explicitly simulate latent immigration and emigration. The viability of the proposed method is shown in an in-depth analysis of outdoor recreation participation on public lands, where the surveyed populations changed rapidly and demographic population closure cannot be assumed even within a single day.




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Bayesian Functional Forecasting with Locally-Autoregressive Dependent Processes

Guillaume Kon Kam King, Antonio Canale, Matteo Ruggiero.

Source: Bayesian Analysis, Volume 14, Number 4, 1121--1141.

Abstract:
Motivated by the problem of forecasting demand and offer curves, we introduce a class of nonparametric dynamic models with locally-autoregressive behaviour, and provide a full inferential strategy for forecasting time series of piecewise-constant non-decreasing functions over arbitrary time horizons. The model is induced by a non Markovian system of interacting particles whose evolution is governed by a resampling step and a drift mechanism. The former is based on a global interaction and accounts for the volatility of the functional time series, while the latter is determined by a neighbourhood-based interaction with the past curves and accounts for local trend behaviours, separating these from pure noise. We discuss the implementation of the model for functional forecasting by combining a population Monte Carlo and a semi-automatic learning approach to approximate Bayesian computation which require limited tuning. We validate the inference method with a simulation study, and carry out predictive inference on a real dataset on the Italian natural gas market.




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Beyond Whittle: Nonparametric Correction of a Parametric Likelihood with a Focus on Bayesian Time Series Analysis

Claudia Kirch, Matthew C. Edwards, Alexander Meier, Renate Meyer.

Source: Bayesian Analysis, Volume 14, Number 4, 1037--1073.

Abstract:
Nonparametric Bayesian inference has seen a rapid growth over the last decade but only few nonparametric Bayesian approaches to time series analysis have been developed. Most existing approaches use Whittle’s likelihood for Bayesian modelling of the spectral density as the main nonparametric characteristic of stationary time series. It is known that the loss of efficiency using Whittle’s likelihood can be substantial. On the other hand, parametric methods are more powerful than nonparametric methods if the observed time series is close to the considered model class but fail if the model is misspecified. Therefore, we suggest a nonparametric correction of a parametric likelihood that takes advantage of the efficiency of parametric models while mitigating sensitivities through a nonparametric amendment. We use a nonparametric Bernstein polynomial prior on the spectral density with weights induced by a Dirichlet process and prove posterior consistency for Gaussian stationary time series. Bayesian posterior computations are implemented via an MH-within-Gibbs sampler and the performance of the nonparametrically corrected likelihood for Gaussian time series is illustrated in a simulation study and in three astronomy applications, including estimating the spectral density of gravitational wave data from the Advanced Laser Interferometer Gravitational-wave Observatory (LIGO).




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A Bayesian Conjugate Gradient Method (with Discussion)

Jon Cockayne, Chris J. Oates, Ilse C.F. Ipsen, Mark Girolami.

Source: Bayesian Analysis, Volume 14, Number 3, 937--1012.

Abstract:
A fundamental task in numerical computation is the solution of large linear systems. The conjugate gradient method is an iterative method which offers rapid convergence to the solution, particularly when an effective preconditioner is employed. However, for more challenging systems a substantial error can be present even after many iterations have been performed. The estimates obtained in this case are of little value unless further information can be provided about, for example, the magnitude of the error. In this paper we propose a novel statistical model for this error, set in a Bayesian framework. Our approach is a strict generalisation of the conjugate gradient method, which is recovered as the posterior mean for a particular choice of prior. The estimates obtained are analysed with Krylov subspace methods and a contraction result for the posterior is presented. The method is then analysed in a simulation study as well as being applied to a challenging problem in medical imaging.




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Sequential Monte Carlo Samplers with Independent Markov Chain Monte Carlo Proposals

L. F. South, A. N. Pettitt, C. C. Drovandi.

Source: Bayesian Analysis, Volume 14, Number 3, 773--796.

Abstract:
Sequential Monte Carlo (SMC) methods for sampling from the posterior of static Bayesian models are flexible, parallelisable and capable of handling complex targets. However, it is common practice to adopt a Markov chain Monte Carlo (MCMC) kernel with a multivariate normal random walk (RW) proposal in the move step, which can be both inefficient and detrimental for exploring challenging posterior distributions. We develop new SMC methods with independent proposals which allow recycling of all candidates generated in the SMC process and are embarrassingly parallelisable. A novel evidence estimator that is easily computed from the output of our independent SMC is proposed. Our independent proposals are constructed via flexible copula-type models calibrated with the population of SMC particles. We demonstrate through several examples that more precise estimates of posterior expectations and the marginal likelihood can be obtained using fewer likelihood evaluations than the more standard RW approach.




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Constrained Bayesian Optimization with Noisy Experiments

Benjamin Letham, Brian Karrer, Guilherme Ottoni, Eytan Bakshy.

Source: Bayesian Analysis, Volume 14, Number 2, 495--519.

Abstract:
Randomized experiments are the gold standard for evaluating the effects of changes to real-world systems. Data in these tests may be difficult to collect and outcomes may have high variance, resulting in potentially large measurement error. Bayesian optimization is a promising technique for efficiently optimizing multiple continuous parameters, but existing approaches degrade in performance when the noise level is high, limiting its applicability to many randomized experiments. We derive an expression for expected improvement under greedy batch optimization with noisy observations and noisy constraints, and develop a quasi-Monte Carlo approximation that allows it to be efficiently optimized. Simulations with synthetic functions show that optimization performance on noisy, constrained problems outperforms existing methods. We further demonstrate the effectiveness of the method with two real-world experiments conducted at Facebook: optimizing a ranking system, and optimizing server compiler flags.




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Separable covariance arrays via the Tucker product, with applications to multivariate relational data

Peter D. Hoff

Source: Bayesian Anal., Volume 6, Number 2, 179--196.

Abstract:
Modern datasets are often in the form of matrices or arrays, potentially having correlations along each set of data indices. For example, data involving repeated measurements of several variables over time may exhibit temporal correlation as well as correlation among the variables. A possible model for matrix-valued data is the class of matrix normal distributions, which is parametrized by two covariance matrices, one for each index set of the data. In this article we discuss an extension of the matrix normal model to accommodate multidimensional data arrays, or tensors. We show how a particular array-matrix product can be used to generate the class of array normal distributions having separable covariance structure. We derive some properties of these covariance structures and the corresponding array normal distributions, and show how the array-matrix product can be used to define a semi-conjugate prior distribution and calculate the corresponding posterior distribution. We illustrate the methodology in an analysis of multivariate longitudinal network data which take the form of a four-way array.




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Maximum Independent Component Analysis with Application to EEG Data

Ruosi Guo, Chunming Zhang, Zhengjun Zhang.

Source: Statistical Science, Volume 35, Number 1, 145--157.

Abstract:
In many scientific disciplines, finding hidden influential factors behind observational data is essential but challenging. The majority of existing approaches, such as the independent component analysis (${mathrm{ICA}}$), rely on linear transformation, that is, true signals are linear combinations of hidden components. Motivated from analyzing nonlinear temporal signals in neuroscience, genetics, and finance, this paper proposes the “maximum independent component analysis” (${mathrm{MaxICA}}$), based on max-linear combinations of components. In contrast to existing methods, ${mathrm{MaxICA}}$ benefits from focusing on significant major components while filtering out ignorable components. A major tool for parameter learning of ${mathrm{MaxICA}}$ is an augmented genetic algorithm, consisting of three schemes for the elite weighted sum selection, randomly combined crossover, and dynamic mutation. Extensive empirical evaluations demonstrate the effectiveness of ${mathrm{MaxICA}}$ in either extracting max-linearly combined essential sources in many applications or supplying a better approximation for nonlinearly combined source signals, such as $mathrm{EEG}$ recordings analyzed in this paper.




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Comment: “Models as Approximations I: Consequences Illustrated with Linear Regression” by A. Buja, R. Berk, L. Brown, E. George, E. Pitkin, L. Zhan and K. Zhang

Roderick J. Little.

Source: Statistical Science, Volume 34, Number 4, 580--583.




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Models as Approximations I: Consequences Illustrated with Linear Regression

Andreas Buja, Lawrence Brown, Richard Berk, Edward George, Emil Pitkin, Mikhail Traskin, Kai Zhang, Linda Zhao.

Source: Statistical Science, Volume 34, Number 4, 523--544.

Abstract:
In the early 1980s, Halbert White inaugurated a “model-robust” form of statistical inference based on the “sandwich estimator” of standard error. This estimator is known to be “heteroskedasticity-consistent,” but it is less well known to be “nonlinearity-consistent” as well. Nonlinearity, however, raises fundamental issues because in its presence regressors are not ancillary, hence cannot be treated as fixed. The consequences are deep: (1) population slopes need to be reinterpreted as statistical functionals obtained from OLS fits to largely arbitrary joint ${x extrm{-}y}$ distributions; (2) the meaning of slope parameters needs to be rethought; (3) the regressor distribution affects the slope parameters; (4) randomness of the regressors becomes a source of sampling variability in slope estimates of order $1/sqrt{N}$; (5) inference needs to be based on model-robust standard errors, including sandwich estimators or the ${x extrm{-}y}$ bootstrap. In theory, model-robust and model-trusting standard errors can deviate by arbitrary magnitudes either way. In practice, significant deviations between them can be detected with a diagnostic test.




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A Conversation with Peter Diggle

Peter M. Atkinson, Jorge Mateu.

Source: Statistical Science, Volume 34, Number 3, 504--521.

Abstract:
Peter John Diggle was born on February 24, 1950, in Lancashire, England. Peter went to school in Scotland, and it was at the end of his school years that he found that he was good at maths and actually enjoyed it. Peter went to Edinburgh to do a maths degree, but transferred halfway through to Liverpool where he completed his degree. Peter studied for a year at Oxford and was then appointed in 1974 as a lecturer in statistics at the University of Newcastle-upon-Tyne where he gained his PhD, and was promoted to Reader in 1983. A sabbatical at the Swedish Royal College of Forestry gave him his first exposure to real scientific data and problems, prompting a move to CSIRO, Australia. After five years with CSIRO where he was Senior, then Principal, then Chief Research Scientist and Chief of the Division of Mathematics and Statistics, he returned to the UK in 1988, to a Chair at Lancaster University. Since 2011 Peter has held appointments at Lancaster and Liverpool, together with honorary appointments at Johns Hopkins, Columbia and Yale. At Lancaster, Peter was the founder and Director of the Medical Statistics Unit (1995–2001), University Dean for Research (1998–2001), EPSRC Senior Fellow (2004–2008), Associate Dean for Research at the School of Health and Medicine (2007–2011), Distinguished University Professor, and leader of the CHICAS Research Group (2007–2017). A Fellow of the Royal Statistical Society since 1974, he was a Member of Council (1983–1985), Joint Editor of JRSSB (1984–1987), Honorary Secretary (1990–1996), awarded the Guy Medal in Silver (1997) and the Barnett Award (2018), Associate Editor of Applied Statistics (1998–2000), Chair of the Research Section Committee (1998–2000), and President (2014–2016). Away from work, Peter enjoys music, playing folk-blues guitar and tenor recorder, and listening to jazz. His running days are behind him, but he can just about hold his own in mixed-doubles badminton with his family. His boyhoood hero was Stirling Moss, and he retains an enthusiasm for classic cars, not least his 1988 Porsche 924S. His favorite authors are George Orwell, Primo Levi and Nigel Slater. This interview was done prior to the fourth Spatial Statistics conference held in Lancaster, July 2017 where a session was dedicated to Peter celebrating his contributions to statistics.




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Assessing the Causal Effect of Binary Interventions from Observational Panel Data with Few Treated Units

Pantelis Samartsidis, Shaun R. Seaman, Anne M. Presanis, Matthew Hickman, Daniela De Angelis.

Source: Statistical Science, Volume 34, Number 3, 486--503.

Abstract:
Researchers are often challenged with assessing the impact of an intervention on an outcome of interest in situations where the intervention is nonrandomised, the intervention is only applied to one or few units, the intervention is binary, and outcome measurements are available at multiple time points. In this paper, we review existing methods for causal inference in these situations. We detail the assumptions underlying each method, emphasize connections between the different approaches and provide guidelines regarding their practical implementation. Several open problems are identified thus highlighting the need for future research.




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ROS Regression: Integrating Regularization with Optimal Scaling Regression

Jacqueline J. Meulman, Anita J. van der Kooij, Kevin L. W. Duisters.

Source: Statistical Science, Volume 34, Number 3, 361--390.

Abstract:
We present a methodology for multiple regression analysis that deals with categorical variables (possibly mixed with continuous ones), in combination with regularization, variable selection and high-dimensional data ($Pgg N$). Regularization and optimal scaling (OS) are two important extensions of ordinary least squares regression (OLS) that will be combined in this paper. There are two data analytic situations for which optimal scaling was developed. One is the analysis of categorical data, and the other the need for transformations because of nonlinear relationships between predictors and outcome. Optimal scaling of categorical data finds quantifications for the categories, both for the predictors and for the outcome variables, that are optimal for the regression model in the sense that they maximize the multiple correlation. When nonlinear relationships exist, nonlinear transformation of predictors and outcome maximize the multiple correlation in the same way. We will consider a variety of transformation types; typically we use step functions for categorical variables, and smooth (spline) functions for continuous variables. Both types of functions can be restricted to be monotonic, preserving the ordinal information in the data. In combination with optimal scaling, three popular regularization methods will be considered: Ridge regression, the Lasso and the Elastic Net. The resulting method will be called ROS Regression (Regularized Optimal Scaling Regression). The OS algorithm provides straightforward and efficient estimation of the regularized regression coefficients, automatically gives the Group Lasso and Blockwise Sparse Regression, and extends them by the possibility to maintain ordinal properties in the data. Extended examples are provided.




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A Conversation with Noel Cressie

Christopher K. Wikle, Jay M. Ver Hoef.

Source: Statistical Science, Volume 34, Number 2, 349--359.

Abstract:
Noel Cressie, FAA is Director of the Centre for Environmental Informatics in the National Institute for Applied Statistics Research Australia (NIASRA) and Distinguished Professor in the School of Mathematics and Applied Statistics at the University of Wollongong, Australia. He is also Adjunct Professor at the University of Missouri (USA), Affiliate of Org 398, Science Data Understanding, at NASA’s Jet Propulsion Laboratory (USA), and a member of the Science Team for NASA’s Orbiting Carbon Observatory-2 (OCO-2) satellite. Cressie was awarded a B.Sc. with First Class Honours in Mathematics in 1972 from the University of Western Australia, and an M.A. and Ph.D. in Statistics in 1973 and 1975, respectively, from Princeton University (USA). Two brief postdoctoral periods followed, at the Centre de Morphologie Mathématique, ENSMP, in Fontainebleau (France) from April 1975–September 1975, and at Imperial College, London (UK) from September 1975–January 1976. His past appointments have been at The Flinders University of South Australia from 1976–1983, at Iowa State University (USA) from 1983–1998, and at The Ohio State University (USA) from 1998–2012. He has authored or co-authored four books and more than 280 papers in peer-reviewed outlets, covering areas that include spatial and spatio-temporal statistics, environmental statistics, empirical-Bayesian and Bayesian methods including sequential design, goodness-of-fit, and remote sensing of the environment. Many of his papers also address important questions in the sciences. Cressie is a Fellow of the Australian Academy of Science, the American Statistical Association, the Institute of Mathematical Statistics, and the Spatial Econometrics Association, and he is an Elected Member of the International Statistical Institute. Noel Cressie’s refereed, unrefereed, and other publications are available at: https://niasra.uow.edu.au/cei/people/UOW232444.html.




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A Conversation with Robert E. Kass

Sam Behseta.

Source: Statistical Science, Volume 34, Number 2, 334--348.

Abstract:
Rob Kass has been been on the faculty of the Department of Statistics at Carnegie Mellon since 1981; he joined the Center for the Neural Basis of Cognition (CNBC) in 1997, and the Machine Learning Department (in the School of Computer Science) in 2007. He served as Department Head of Statistics from 1995 to 2004 and served as Interim Co-Director of the CNBC 2015–2018. He became the Maurice Falk Professor of Statistics and Computational Neuroscience in 2016. Kass has served as Chair of the Section for Bayesian Statistical Science of the American Statistical Association, Chair of the Statistics Section of the American Association for the Advancement of Science, founding Editor-in-Chief of the journal Bayesian Analysis and Executive Editor of Statistical Science . He is an elected Fellow of the American Statistical Association, the Institute of Mathematical Statistics and the American Association for the Advancement of Science. He has been recognized by the Institute for Scientific Information as one of the 10 most highly cited researchers, 1995–2005, in the category of mathematics. Kass is the recipient of the 2017 Fisher Award and lectureship by the Committee of the Presidents of the Statistical Societies. This interview took place at Carnegie Mellon University in November 2017.




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A Kernel Regression Procedure in the 3D Shape Space with an Application to Online Sales of Children’s Wear

Gregorio Quintana-Ortí, Amelia Simó.

Source: Statistical Science, Volume 34, Number 2, 236--252.

Abstract:
This paper is focused on kernel regression when the response variable is the shape of a 3D object represented by a configuration matrix of landmarks. Regression methods on this shape space are not trivial because this space has a complex finite-dimensional Riemannian manifold structure (non-Euclidean). Papers about it are scarce in the literature, the majority of them are restricted to the case of a single explanatory variable, and many of them are based on the approximated tangent space. In this paper, there are several methodological innovations. The first one is the adaptation of the general method for kernel regression analysis in manifold-valued data to the three-dimensional case of Kendall’s shape space. The second one is its generalization to the multivariate case and the addressing of the curse-of-dimensionality problem. Finally, we propose bootstrap confidence intervals for prediction. A simulation study is carried out to check the goodness of the procedure, and a comparison with a current approach is performed. Then, it is applied to a 3D database obtained from an anthropometric survey of the Spanish child population with a potential application to online sales of children’s wear.




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A Conversation with Dick Dudley

Vladimir Koltchinskii, Richard Nickl, Philippe Rigollet.

Source: Statistical Science, Volume 34, Number 1, 169--175.

Abstract:
Richard Mansfield Dudley (Dick Dudley) was born in 1938. He received the A.B. from Harvard in 1952 and the Ph.D. from Princeton in 1962 (under the supervision of Gilbert Hunt and Edward Nelson). Following an appointment at UC Berkeley as an assistant professor, he joined the Department of Mathematics at MIT in 1967. Dick Dudley has made fundamental contributions to the theory of Gaussian processes and Probability in Banach Spaces. Among his major achievements is the development of a general framework for empirical processes theory, in particular, for uniform central limit theorems. These results have had and continue having tremendous impact in contemporary statistics and in mathematical foundations of machine learning. A more extensive biographical sketch is contained in the preface to the Selected works of R. M. Dudley (editors: E. Giné, V. Koltchinskii and R. Norvaisa) published in 2010. This conversation took place (mostly, via email) in the fall of 2017.




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A Conversation with Piet Groeneboom

Geurt Jongbloed.

Source: Statistical Science, Volume 34, Number 1, 156--168.

Abstract:
Petrus (Piet) Groeneboom was born in Scheveningen in 1941 and grew up in Voorburg. Both villages are located near The Hague in The Netherlands; Scheveningen actually being part of The Hague. He attended the gymnasium of the Huygens lyceum. In 1959, he entered the University of Amsterdam, where he studied psychology. After his “candidate” exam (comparable to BSc) in 1963, he worked at the psychological laboratory of the University of Amsterdam until 1966. In 1965, he took up mathematics as a part-time study. After having obtained his master’s degree in 1971, he had a position at the psychological laboratory again until 1973, when he was appointed to the Mathematical Center in Amsterdam. There, he wrote between 1975 and 1979 his Ph.D. thesis with Kobus Oosterhoff as advisor, graduating in 1979. After a period of two years as visiting professor at the University of Washington (UW) in Seattle, Piet moved back to the Mathematical Center until he was appointed full professor of statistics at the University of Amsterdam in 1984. Four years later, he moved to Delft University of Technology where he became professor of statistics and stayed until his retirement in 2006. Between 2000 and 2006 he also held a part-time professorship at the Vrije Universiteit in Amsterdam. From 1999 till 2013 he was Affiliate Professor at the statistics department of UW, Seattle. Apart from being visiting professor at the UW in Seattle, he was also visiting professor at Stanford University, Université Paris 6 and ETH Zürich. Piet is well known for his work on shape constrained statistical inference. He worked on asymptotic theory for these problems, created algorithms to compute nonparametric estimates in such models and applied these models to real data. He also worked on interacting particle systems, extreme value analysis and efficiency theory for testing procedures. Piet (co-)authored four books and 64 papers and served as promotor of 13 students. He is the recipient of the 1985 Rollo Davidson prize, a fellow of the IMS and elected member of the ISI. In 2015, he delivered the Wald lecture at the Joint Statistical Meeting in Montreal. Piet and his wife Marijke live in Naarden. He has two sons, Thomas and Tim, and (since June 12, 2018) one grandson, Tarik. This conversation was held at Piet’s house in Naarden, on February 28 and April 24, 2018.




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[Silhouette of a pregant woman smoking with death skull inside womb, 29 January 1994] / design: Biman Mullick.

London, [29 January 1994]




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Reese Witherspoon and I Wear the Same Comfy Hoka One One Sneakers to Run Errands 

Once you try them, you’ll never want to wear anything else




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Brain-Derived Neurotrophic Factor Protection of Cortical Neurons from Serum Withdrawal-Induced Apoptosis Is Inhibited by cAMP

Steven Poser
Jun 1, 2003; 23:4420-4427
Cellular




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Daily Marijuana Use Is Not Associated with Brain Morphometric Measures in Adolescents or Adults

Barbara J. Weiland
Jan 28, 2015; 35:1505-1512
Neurobiology of Disease




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Grey Matter Volume Differences Associated with Extremely Low Levels of Cannabis Use in Adolescence

Catherine Orr
Mar 6, 2019; 39:1817-1827
BehavioralSystemsCognitive




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Endothelial Adora2a Activation Promotes Blood-Brain Barrier Breakdown and Cognitive Impairment in Mice with Diet-Induced Insulin Resistance

Masaki Yamamoto
May 22, 2019; 39:4179-4192
Neurobiology of Disease




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Dendritic spines of CA 1 pyramidal cells in the rat hippocampus: serial electron microscopy with reference to their biophysical characteristics

KM Harris
Aug 1, 1989; 9:2982-2997
Articles




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Broadband Shifts in Local Field Potential Power Spectra Are Correlated with Single-Neuron Spiking in Humans

Jeremy R. Manning
Oct 28, 2009; 29:13613-13620
BehavioralSystemsCognitive




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The highly irregular firing of cortical cells is inconsistent with temporal integration of random EPSPs

WR Softky
Jan 1, 1993; 13:334-350
Articles




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High-Level Neuronal Expression of A{beta}1-42 in Wild-Type Human Amyloid Protein Precursor Transgenic Mice: Synaptotoxicity without Plaque Formation

Lennart Mucke
Jun 1, 2000; 20:4050-4058
Cellular




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please come play with me baby straight v




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Microsoft Covers All the Bases With Impressive Surface Lineup

Microsoft has introduced a slew of new products, including the Surface Go 2, the Surface Book 3, Surface Headphones 2 and Surface Earbuds. Both the Surface Go 2 and the Surface Book 3 come in consumer and corporate versions. "The two products are very different," noted Rob Enderle, principal analyst at the Enderle Group. "The Go 2 is a high-value product -- the Surface Book 3 high innovation."




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MakuluLinux Delivers Modernity With New Core Platform

If you are looking for a well-designed Linux distro that is far from mainstream, loaded with performance features not found elsewhere, check out the 2020 upgrade of the MakuluLinux Core distro. It could change your perspective on what a daily computing driver should offer. Developer Jacque Montague Raymer recently released the 2020 edition of MakuluLinux Core OS.




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6 Signs You May Be Ready for a CRM Switch

In today's evolving business environment, every operational decision is critical -- and that includes best practices for managing the customer journey. The CRM platform is an integral part of the process. In fact, 91 percent of companies with more than 11 employees use a CRM system. Because of the time it saves and the structure CRM delivers, it can seem daunting for businesses to make a switch.




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Contact Tracing With Salesforce

Contact tracing is a big job, like trying to drain an ocean with a teaspoon. It involves finding people who have been exposed to the coronavirus and testing them to determine if they are infected or are carriers. Public health officials then can take necessary steps to prevent the virus' spread. It's a perfect fit for CRM, and Salesforce's core technology is coming to the forefront.




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Health Insurance, Banking, Oil Industries Met with Koch, Chamber, Glenn Beck to Plot 2010 Election




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Israeli Jews at odds with liberal brethren in US




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Central bank innovation - from Switzerland to the world

Speech by Mr Agustín Carstens, General Manager of the BIS, at the Founding Ceremony, Swiss Centre BIS Innovation Hub, Zurich, 8 October 2019.




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Interview with Brazil's EXAME

Original quotes from interview by Mr Agustin Carstens, General Manager of the BIS, with Exame, conducted by Mr Felipe Serrano on 9 October 2019 and published on 24 October 2019.




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The Right Temporoparietal Junction Is Causally Associated with Embodied Perspective-taking

A prominent theory claims that the right temporoparietal junction (rTPJ) is especially associated with embodied processes relevant to perspective-taking. In the present study, we use high-definition transcranial direct current stimulation to provide evidence that the rTPJ is causally associated with the embodied processes underpinning perspective-taking. Eighty-eight young human adults were stratified to receive either rTPJ or dorsomedial PFC anodal high-definition transcranial direct current stimulation in a sham-controlled, double-blind, repeated-measures design. Perspective-tracking (line-of-sight) and perspective-taking (embodied rotation) were assessed using a visuo-spatial perspective-taking task that required understanding what another person could see or how they see it, respectively. Embodied processing was manipulated by positioning the participant in a manner congruent or incongruent with the orientation of an avatar on the screen. As perspective-taking, but not perspective-tracking, is influenced by bodily position, this allows the investigation of the specific causal role for the rTPJ in embodied processing. Crucially, anodal stimulation to the rTPJ increased the effect of bodily position during perspective-taking, whereas no such effects were identified during perspective-tracking, thereby providing evidence for a causal role for the rTPJ in the embodied component of perspective-taking. Stimulation to the dorsomedial PFC had no effect on perspective-tracking or taking. Therefore, the present study provides support for theories postulating that the rTPJ is causally involved in embodied cognitive processing relevant to social functioning.

SIGNIFICANCE STATEMENT The ability to understand another's perspective is a fundamental component of social functioning. Adopting another perspective is thought to involve both embodied and nonembodied processes. The present study used high-definition transcranial direct current stimulation (HD-tDCS) and provided causal evidence that the right temporoparietal junction is involved specifically in the embodied component of perspective-taking. Specifically, HD-tDCS to the right temporoparietal junction, but not another hub of the social brain (dorsomedial PFC), increased the effect of body position during perspective-taking, but not tracking. This is the first causal evidence that HD-tDCS can modulate social embodied processing in a site-specific and task-specific manner.




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Neural Correlates of Strategy Switching in the Macaque Orbital Prefrontal Cortex

We can adapt flexibly to environment changes and search for the most appropriate rule to a context. The orbital prefrontal cortex (PFo) has been associated with decision making, rule generation and maintenance, and more generally has been considered important for behavioral flexibility. To better understand the neural mechanisms underlying the flexible behavior, we studied the ability to generate a switching signal in monkey PFo when a strategy is changed. In the strategy task, we used a visual cue to instruct two male rhesus monkeys either to repeat their most recent choice (i.e., stay strategy) or to change it (i.e., shift strategy). To identify the strategy switching-related signal, we compared nonswitch and switch trials, which cued the same or a different strategy from the previous trial, respectively. We found that the switching-related signal emerged during the cue presentation and it was combined with the strategy signal in a subpopulation of cells. Moreover, the error analysis showed that the activity of the switch-related cells reflected whether the monkeys erroneously switched or not the strategy, rather than what was required for that trial. The function of the switching signal could be to prompt the use of different strategies when older strategies are no longer appropriate, conferring the ability to adapt flexibly to environmental changes. In our task, the switching signal might contribute to the implementation of the strategy cued, overcoming potential interference effects from the strategy previously cued. Our results support the idea that ascribes to PFo an important role for behavioral flexibility.

SIGNIFICANCE STATEMENT We can flexibly adapt our behavior to a changing environment. One of the prefrontal areas traditionally associated with the ability to adapt to new contingencies is the orbital prefrontal cortex (PFo). We analyzed the switching related activity using a strategy task in which two rhesus monkeys were instructed by a visual cue either to repeat or change their most recent choice, respectively using a stay or a shift strategy. We found that PFo neurons were modulated by the strategy switching signal, pointing to the importance of PFo in behavioral flexibility by generating control over the switching of strategies.