era [ASAP] <italic toggle="yes">De Novo</italic> Synthesis of the DEF-Ring Stereotriad Core of the <italic toggle="yes">Veratrum</italic> Alkaloids By feedproxy.google.com Published On :: Thu, 30 Apr 2020 04:00:00 GMT The Journal of Organic ChemistryDOI: 10.1021/acs.joc.0c00685 Full Article
era [ASAP] Correction to Specific <italic toggle="yes">Z</italic>-Selectivity in the Oxidative Isomerization of Allyl Ethers to Generate Geometrically Defined <italic toggle="yes">Z</italic>-Enol Ethers Using a Coba By feedproxy.google.com Published On :: Mon, 04 May 2020 04:00:00 GMT The Journal of Organic ChemistryDOI: 10.1021/acs.joc.0c00990 Full Article
era Multifunctional red carbon dots: a theranostic platform for magnetic resonance imaging and fluorescence imaging-guided chemodynamic therapy By feeds.rsc.org Published On :: Analyst, 2020, Advance ArticleDOI: 10.1039/D0AN00267D, PaperWentao Wang, Qicheng Zhang, Ming Zhang, Yihan Liu, Jian Shen, Ninglin Zhou, Xiaoyuan Lu, Changhong ZhaoIn recent years, carbon dots (CDs) with red-emitting wavelengths have received increasing attention in cancer therapy and imaging.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
era Profiling of immune-cancer interactions at the single cell level using microfluidic well array By feeds.rsc.org Published On :: Analyst, 2020, Accepted ManuscriptDOI: 10.1039/D0AN00110D, PaperHonglei Tu, Zhuhao Wu, Yu Xia, Hui Chen, Hang Hu, Zhao Ding, Fuling Zhou, Shishang GuoCancer immunotherapy has achieved great success in hematological cancers. However, immune cells are highly heterogeneous population and can vary highly on clonal expansion, migration and function status, making it difficult...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
era Accelerated non-crosslinking assembly of DNA-functionalized nanoparticles in alcoholic solvents: for application in the identification of clear liquors By feeds.rsc.org Published On :: Analyst, 2020, 145,3229-3235DOI: 10.1039/D0AN00029A, PaperLuyang Wang, Guoqing Wang, Yali Shi, Lan Zhang, Ran An, Tohru Takarada, Mizuo Maeda, Xingguo LiangAccelerated aggregation of DNA-functionalized gold nanoparticles is discovered in alcoholic solvents upon adding full-match DNA and is potentially useful for the identification of Baijiu.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
era Recent developments of nanoenzyme-based colorimetric sensors for heavy metal detection and the interaction mechanism By feeds.rsc.org Published On :: Analyst, 2020, 145,3173-3187DOI: 10.1039/D0AN00339E, Critical ReviewZhengquan Yan, Hua Yuan, Qi Zhao, Lin Xing, Xiaoyu Zheng, Weiguo Wang, Yulei Zhao, Yang Yu, Lei Hu, Wenli YaoThis work highlights the application and interaction mechanism of metal nanoparticles, metal oxides, metal sulfides, graphene-based nanomaterials and G-quadruplex, etc. in nanoenzyme-based colorimetric sensors.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
era An efficient assay for identification and quantitative evaluation of potential polysialyltransferase inhibitors By feeds.rsc.org Published On :: Analyst, 2020, Accepted ManuscriptDOI: 10.1039/D0AN00721H, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Xiaoxiao Guo, Jodie R Malcolm, Marrwa M Ali, Goreti Ribeiro Morais, Steve Shnyder, Paul Loadman, L H Patterson, Robert Andrew FalconerThe polysialyltransferases (polySTs) catalyse the polymerisation of polysialic acid, which plays an important role in tumour metastasis. While assays are available to assess polyST enzyme activity, there is no methodology...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
era [ASAP] SCRaMbLEing of a Synthetic Yeast Chromosome with Clustered Essential Genes Reveals Synthetic Lethal Interactions By feedproxy.google.com Published On :: Fri, 17 Apr 2020 04:00:00 GMT ACS Synthetic BiologyDOI: 10.1021/acssynbio.0c00059 Full Article
era [ASAP] MAPPS: A Web-Based Tool for Metabolic Pathway Prediction and Network Analysis in the Postgenomic Era By feedproxy.google.com Published On :: Wed, 29 Apr 2020 04:00:00 GMT ACS Synthetic BiologyDOI: 10.1021/acssynbio.9b00397 Full Article
era [ASAP] A Chemical Switch System to Modulate Chimeric Antigen Receptor T Cell Activity through Proteolysis-Targeting Chimaera Technology By feedproxy.google.com Published On :: Thu, 30 Apr 2020 04:00:00 GMT ACS Synthetic BiologyDOI: 10.1021/acssynbio.9b00476 Full Article
era [ASAP] Multiplex Generation, Tracking, and Functional Screening of Substitution Mutants Using a CRISPR/Retron System By feedproxy.google.com Published On :: Mon, 04 May 2020 04:00:00 GMT ACS Synthetic BiologyDOI: 10.1021/acssynbio.0c00002 Full Article
era [ASAP] A Selective Modulator of Peroxisome Proliferator-Activated Receptor ? with an Unprecedented Binding Mode By feedproxy.google.com Published On :: Mon, 20 Apr 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.9b01786 Full Article
era [ASAP] Synthesis and Structure–Activity Relationships of Arylsulfonamides as AIMP2-DX2 Inhibitors for the Development of a Novel Anticancer Therapy By feedproxy.google.com Published On :: Tue, 21 Apr 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.9b01961 Full Article
era [ASAP] Discovery, Structure–Activity Relationship, and Biological Activity of Histone-Competitive Inhibitors of Histone Acetyltransferases P300/CBP By feedproxy.google.com Published On :: Tue, 21 Apr 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.9b02164 Full Article
era [ASAP] Pyridine-Embedded Phenothiazinium Dyes as Lysosome-Targeted Photosensitizers for Highly Efficient Photodynamic Antitumor Therapy By feedproxy.google.com Published On :: Tue, 21 Apr 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.0c00280 Full Article
era [ASAP] Molecular Interactions of Pyrazine-Based Compounds to Proteins By feedproxy.google.com Published On :: Fri, 24 Apr 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.9b02021 Full Article
era [ASAP] Discovery of M-808 as a Highly Potent, Covalent, Small-Molecule Inhibitor of the Menin–MLL Interaction with Strong <italic toggle="yes">In Vivo</italic> Antitumor Activity By feedproxy.google.com Published On :: Mon, 27 Apr 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.0c00547 Full Article
era [ASAP] Bioisosteric Discovery of NPA101.3, a Second-Generation RET/VEGFR2 Inhibitor Optimized for Single-Agent Polypharmacology By feedproxy.google.com Published On :: Tue, 28 Apr 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.9b01336 Full Article
era [ASAP] Dual-Target Inhibitors Based on HDACs: Novel Antitumor Agents for Cancer Therapy By feedproxy.google.com Published On :: Thu, 30 Apr 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.0c00491 Full Article
era [ASAP] Degradation versus Inhibition: Development of Proteolysis-Targeting Chimeras for Overcoming Statin-Induced Compensatory Upregulation of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase By feedproxy.google.com Published On :: Mon, 04 May 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.0c00339 Full Article
era [ASAP] Targeting ALK2: An Open Science Approach to Developing Therapeutics for the Treatment of Diffuse Intrinsic Pontine Glioma By feedproxy.google.com Published On :: Tue, 05 May 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.0c00395 Full Article
era [ASAP] Ruthenium(II) Complex Containing a Redox-Active Semiquinonate Ligand as a Potential Chemotherapeutic Agent: From Synthesis to <italic toggle="yes">In Vivo</italic> Studies By feedproxy.google.com Published On :: Thu, 07 May 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.0c00431 Full Article
era [ASAP] Chimeric Peptidomimetics of SOCS 3 Able to Interact with JAK2 as Anti-inflammatory Compounds By feedproxy.google.com Published On :: Mon, 30 Mar 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.9b00664 Full Article
era [ASAP] Cancer Immunotherapy through the Inhibition of Diacylglycerol Kinases Alpha and Zeta By feedproxy.google.com Published On :: Wed, 01 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00118 Full Article
era [ASAP] Therapeutic Potential of Targeted Nanoparticles and Perspective on Nanotherapies By feedproxy.google.com Published On :: Thu, 02 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00075 Full Article
era [ASAP] Design, Synthesis, and Pharmacological Evaluation of Second Generation EZH2 Inhibitors with Long Residence Time By feedproxy.google.com Published On :: Thu, 02 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00045 Full Article
era [ASAP] Combined Peptide and Small-Molecule Approach toward Nonacidic THIQ Inhibitors of the KEAP1/NRF2 Interaction By feedproxy.google.com Published On :: Fri, 10 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.9b00594 Full Article
era [ASAP] Novel Dithiolane-Based Ligands Combining Sigma and NMDA Receptor Interactions as Potential Neuroprotective Agents By feedproxy.google.com Published On :: Fri, 10 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00129 Full Article
era [ASAP] Artemisinin Derivatives with Antimelanoma Activity Show Inhibitory Effect against Human DNA Topoisomerase 1 By feedproxy.google.com Published On :: Tue, 14 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00131 Full Article
era [ASAP] Complete Regression of Carcinoma via Combined C-RAF and EGFR Targeted Therapy By feedproxy.google.com Published On :: Tue, 14 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00159 Full Article
era [ASAP] Characterization of Specific <italic toggle="yes">N</italic>-a-Acetyltransferase 50 (Naa50) Inhibitors Identified Using a DNA Encoded Library By feedproxy.google.com Published On :: Wed, 15 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00029 Full Article
era [ASAP] Discovery of CPI-1612: A Potent, Selective, and Orally Bioavailable EP300/CBP Histone Acetyltransferase Inhibitor By feedproxy.google.com Published On :: Mon, 27 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00155 Full Article
era [ASAP] PROTAC Compounds Targeting a-Synuclein Protein for Treating Neurogenerative Disorders: Alzheimer’s and Parkinson’s Diseases By feedproxy.google.com Published On :: Tue, 28 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00192 Full Article
era [ASAP] Ligand Design for Cereblon Based Immunomodulatory Therapy By feedproxy.google.com Published On :: Fri, 08 May 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00214 Full Article
era Germany Facing Mass Blackouts Because The Wind And Solar Won’t Cooperate By latestsolarnews.com Published On :: Sat, 04 Mar 2017 19:59:09 +0000 Germany’s energy network nearly broken down in January because of poor execution from wind turbines and sun based boards, as indicated by information from a noteworthy exchange union. Wind and sunlight based power plants failed to meet expectations in January, 2017, as a result of shady climate with almost no wind, setting the phase for … The post Germany Facing Mass Blackouts Because The Wind And Solar Won’t Cooperate appeared first on LatestSolarNews. Full Article News
era Anna Maria Maiolino, Entre pausas / texts by Anna Maria Maiolino, Tania Rivera and Randy Kennedy By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - NC200.M27 A4 2018 Full Article
era On desire: BIII / Herausgeber, Bernd Kracke, Marc Ries By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N6498.V53 B15 2018 Full Article
era Altered states: Substanzen in der zeitgenössischen Kunst = substances in contemporary art / herausgegeben von = edited by Milena Mercer ; Texte = texts, Max Daly ... [and thirteen others] By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N8251.S555 A48 2018 Full Article
era Neuer Norden Zürich: ein Kunstprojekt im öffentlichen Raum, 9. Juni-2. September 2018 = New north Zurich: a public art project, 9th of June-2nd of September 2018 / herausgegeben von Christoph Doswald ; fotografiert von Pierluigi Macor ; Übe By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N6496.3.S9 Z876 2018 Full Article
era Exercises in freedom: polnische Konzeptkunst, 1968-1981 = Polish conceptualism, 1968-1981 / Herausgeber = editor, Staatliche Kunstsammlungen Dresden, Kupferstich-Kabinett, Björn Egging By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N7255.P6 E88 2018 Full Article
era Jakob Mohr / herausgegeben von Doris Noell-Rumpeltes + Thomas Röske By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - NC251.M64 J35 2018 Full Article
era Socially engaged art and the neoliberal city / Cecilie Sachs Olsen By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N72.A76 O47 2019 Full Article
era Yves Netzhammer: Installationen 2008-2018 / Gesamtverantwortung, Katharina Epprecht ; Hrsg. von Jennifer Burkard ; Autoren, Claudia Bader [and four others] By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N7153.N47 A4 2018 Full Article
era Per Kirkeby / herausgegeben von Florian Steininger ; mit Beiträgen von Robert Fleck, Per Kirkeby, Florian Steininger By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - ND723.K53 A4 2018 Full Article
era My art guide: Venice 2019, 58th Biennale Arte: national participations, collateral events, exhibitions, events, museums, foundations, restaurants, hotels, city maps By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N6488.I8 V433 2019 A11 Full Article
era Inside Tangier: houses & gardens / Nicolò Castellini Baldissera ; photography, Guido Taroni ; foreword, Hamish Bowles By library.mit.edu Published On :: Sun, 22 Mar 2020 06:00:01 EDT Rotch Library - NK2087.75.A1 B35 2019 Full Article
era Medea muckt auf: Radikale Künstlerinnen hinter dem Eisernen Vorhang = The Medea insurrection: radical women artists behind the Iron Curtain / Herausgeber: Staatliche Kunstsammlungen Dresden, Susanne Altmann, Katarina Lozo, Hilke Wagner By library.mit.edu Published On :: Sun, 22 Mar 2020 06:00:01 EDT Rotch Library - N8354.M43 2019 Full Article
era London art worlds: mobile, contingent, and ephemeral networks, 1960-1980 / edited by Jo Applin, Catherine Spencer, and Amy Tobin By library.mit.edu Published On :: Sun, 26 Apr 2020 06:00:01 EDT Rotch Library - N6770.L6495 2018 Full Article
era Theatre and performance in the neoliberal university : responses to an academy in crisis / edited by Kim Solga. By darius.uleth.ca Published On :: Full Article
era Cognitive approaches to early modern Spanish literature / edited by Isabel Jaén and Julien Jacques Simon By library.mit.edu Published On :: Sun, 11 Sep 2016 06:09:55 EDT Hayden Library - PQ6022.C64 2016 Full Article