in Donor-derived DNA variability in fingernails of acute myeloid leukemia patients after allogeneic hematopoietic stem cell transplantation detected by direct PCR By feeds.nature.com Published On :: 2020-05-09 Full Article
in Safety and efficacy of chimeric antigen receptor T-cell therapy in relapsed/refractory multiple myeloma with renal impairment By feeds.nature.com Published On :: 2020-05-09 Full Article
in NT5DC2 promotes tumor cell proliferation by stabilizing EGFR in hepatocellular carcinoma By feeds.nature.com Published On :: 2020-05-07 Full Article
in Irradiation induces cancer lung metastasis through activation of the cGAS–STING–CCL5 pathway in mesenchymal stromal cells By feeds.nature.com Published On :: 2020-05-07 Full Article
in Differential effectiveness of tyrosine kinase inhibitors in 2D/3D culture according to cell differentiation, p53 status and mitochondrial respiration in liver cancer cells By feeds.nature.com Published On :: 2020-05-07 Full Article
in QKI deficiency leads to osteoporosis by promoting RANKL-induced osteoclastogenesis and disrupting bone metabolism By feeds.nature.com Published On :: 2020-05-07 Full Article
in WTAP and BIRC3 are involved in the posttranscriptional mechanisms that impact on the expression and activity of the human lactonase PON2 By feeds.nature.com Published On :: 2020-05-07 Full Article
in LncRNA <i>SNORD3A</i> specifically sensitizes breast cancer cells to 5-FU by sponging miR-185-5p to enhance UMPS expression By feeds.nature.com Published On :: 2020-05-07 Full Article
in NF-kappa B interacting long noncoding RNA enhances the Warburg effect and angiogenesis and is associated with decreased survival of patients with gliomas By feeds.nature.com Published On :: 2020-05-07 Full Article
in MicroRNA let-7c (MIRLET7C; let-7c), miR-99a and miR-125b as prognostic markers of luminal breast cancer By feeds.nature.com Published On :: 2014-12-18 Studies in patient samples and cell culture suggest let-7c, miR-99a and miR-125b could serve as prognostic markers in patients with estrogen receptor–positive luminal breast cancers. Full Article
in Chromosome 11 open reading frame 30 (C11orf30), calpain small subunit 1 (CAPNS1; CAPN4), signal transducer and activator of transcription 6 (STAT6) and ankyrin repeat domain 27 (ANKRD27) as diagnostic markers for eosinophilic esophagitis (EoE) By feeds.nature.com Published On :: 2014-12-18 Genomewide association studies identified four genes that could serve as diagnostic markers and/or therapeutic targets for EoE. Full Article
in Tumor-selective delivery of antisense oligomers (antimiRs) against oncogenic microRNAs By feeds.nature.com Published On :: 2014-12-18 miRNA-targeted antimiRs conjugated to a peptide with a low pH–induced transmembrane structure (pHLIP) could help treat solid tumors. Full Article
in RNAi against therapeutic targets with short interfering ribonucleic neutrals (siRNNs) By feeds.nature.com Published On :: 2014-12-18 siRNNs could enable RNAi knockdown of therapeutic targets in a broader range of cells and tissue types than siRNA. Full Article
in Extending therapeutic protein half-lives via fusion to affibodies with pH-dependent binding to neonatal Fc receptor By feeds.nature.com Published On :: 2014-12-18 Fusing therapeutic proteins to affibodies with pH-dependent binding to neonatal Fc receptor could improve the proteins' half-lives. Full Article
in Dermatophagoides pteronyssinus peptidase 1 (DERP1) By feeds.nature.com Published On :: 2014-12-18 In vitro and rat studies suggest inhibiting the enzymatic activity of house dust mite (HDM) allergens could help treat allergic asthma. Full Article
in Influenza A virus hemagglutinin By feeds.nature.com Published On :: 2014-12-18 Cell and mouse studies have identified pentacyclic triterpenoid analogs that could help treat influenza infections and have lower risk for resistance than amantadine. Full Article
in Angiopoietin 2 (ANG2; ANGPT2); placental growth factor (PGF; PlGF); tissue inhibitor of metalloproteinases 3 (TIMP3) By feeds.nature.com Published On :: 2014-12-18 Mouse studies suggest inhibiting PGF could help treat hypertension. Full Article
in c-jun N-terminal kinase (JNK); MAP kinase 1 (MAPK1; ERK-2); MAPK3 (ERK-1) By feeds.nature.com Published On :: 2014-12-18 In vitro and rodent studies suggest ophiopogonin D could help prevent doxorubicin-induced cardiotoxicity. Full Article
in Sortilin 1 (SORT1) By feeds.nature.com Published On :: 2014-12-18 Mouse studies suggest inhibiting SORT1 in macrophages and T cells could help treat atherosclerosis. Full Article
in Topoisomerase II binding protein 1 (TOPBP1) By feeds.nature.com Published On :: 2014-12-18 Mouse and cell culture studies suggest inhibiting TOPBP1 could help treat cancer. Full Article
in Cyclin dependent kinase 7 (CDK7); v-myc myelocytomatosis viral related oncogene neuroblastoma derived (MYCN; NMYC) By feeds.nature.com Published On :: 2014-12-18 In vitro and mouse studies suggest THZ1, a covalent CDK7 inhibitor, could help treat neuroblastoma and other cancers driven by MYCN and other c-MYC (MYC)-family oncoproteins. Full Article
in Tripartite motif containing 37 (TRIM37) By feeds.nature.com Published On :: 2014-12-18 In vitro and mouse studies suggest inhibiting TRIM37 could help treat breast cancer. Full Article
in Estrogen receptor; LYN kinase (LYN); phosphoinositide 3-kinase (PI3K) By feeds.nature.com Published On :: 2014-12-18 Studies in mice and human samples suggest inhibiting LYN could help treat estrogen receptor–positive breast cancers resistant to anti-estrogen therapy. Full Article
in Resurrecting a magic bullet By feeds.nature.com Published On :: 2014-12-18 Heidelberg Pharma has resuscitated a long-dead ADC toxin with updated conjugation techniques, and its partner Roche has thrown the company a lifeline that could help validate the platform. Full Article
in Neutralizing the negatives of RNAi By feeds.nature.com Published On :: 2014-12-18 The siRNN technology that Solstice licensed from UCSD could take RNAi-based therapies to tissues outside the liver and expand their use to a host of new diseases. Full Article
in Pac1/LIS1 stabilizes an uninhibited conformation of dynein to coordinate its localization and activity By feeds.nature.com Published On :: 2020-04-27 Full Article
in Tissue-resident ductal macrophages survey the mammary epithelium and facilitate tissue remodelling By feeds.nature.com Published On :: 2020-04-27 Full Article
in Myeloid PTEN promotes chemotherapy-induced NLRP3-inflammasome activation and antitumour immunity By feeds.nature.com Published On :: 2020-05-04 Full Article
in In vitro capture and characterization of embryonic rosette-stage pluripotency between naive and primed states By feeds.nature.com Published On :: 2020-05-04 Full Article
in Bridging naïve and primed pluripotency By feeds.nature.com Published On :: 2020-05-04 Full Article
in Differentiation of transplanted haematopoietic stem cells tracked by single-cell transcriptomic analysis By feeds.nature.com Published On :: 2020-05-04 Full Article
in Transcription factors in ferroptotic cell death By feeds.nature.com Published On :: 2020-03-03 Full Article
in MicroRNA binding site polymorphism in inflammatory genes associated with colorectal cancer: literature review and bioinformatics analysis By feeds.nature.com Published On :: 2020-03-23 Full Article
in In vivo antitumor activity by dual stromal and tumor-targeted oncolytic measles viruses By feeds.nature.com Published On :: 2020-03-31 Full Article
in Oncolytic adenovirus encoding LIGHT (TNFSF14) inhibits tumor growth via activating anti-tumor immune responses in 4T1 mouse mammary tumor model in immune competent syngeneic mice By feeds.nature.com Published On :: 2020-04-20 Full Article
in TMB: a promising immune-response biomarker, and potential spearhead in advancing targeted therapy trials By feeds.nature.com Published On :: 2020-04-28 Full Article
in Immunostimulatory oncolytic virotherapy for multiple myeloma targeting 4-1BB and/or CD40 By feeds.nature.com Published On :: 2020-05-01 Full Article
in UNC5B mediates G2/M phase arrest of bladder cancer cells by binding to CDC14A and P53 By feeds.nature.com Published On :: 2020-05-06 Full Article
in The rise of integrated quantum photonics By feeds.nature.com Published On :: 2020-04-28 Full Article
in Machine intelligence lights up imaging By feeds.nature.com Published On :: 2020-04-28 Full Article
in Author Correction: Quantum wave–particle superposition in a delayed-choice experiment By feeds.nature.com Published On :: 2020-04-28 Full Article
in Engineering nanomedicines through boosting immunogenic cell death for improved cancer immunotherapy By feeds.nature.com Published On :: 2020-04-21 Full Article
in Cardamonin protects against lipopolysaccharide-induced myocardial contractile dysfunction in mice through Nrf2-regulated mechanism By feeds.nature.com Published On :: 2020-04-21 Full Article
in Nintedanib inhibits keloid fibroblast functions by blocking the phosphorylation of multiple kinases and enhancing receptor internalization By feeds.nature.com Published On :: 2020-04-23 Full Article
in Diabetes downregulates peptide transporter 1 in the rat jejunum: possible involvement of cholate-induced FXR activation By feeds.nature.com Published On :: 2020-04-27 Full Article
in An in vitro Förster resonance energy transfer-based high-throughput screening assay identifies inhibitors of SUMOylation E2 Ubc9 By feeds.nature.com Published On :: 2020-04-27 Full Article
