wit Efficacy of Melatonin in Children With Postconcussive Symptoms: A Randomized Clinical Trial By pediatrics.aappublications.org Published On :: 2020-04-01T01:00:57-07:00 BACKGROUND: Approximately 25% of children with concussion have persistent postconcussive symptoms (PPCS) with resultant significant impacts on quality of life. Melatonin has significant neuroprotective properties, and promising preclinical data suggest its potential to improve outcomes after traumatic brain injury. We hypothesized that treatment with melatonin would result in a greater decrease in PPCS symptoms when compared with a placebo. METHODS: We conducted a randomized, double-blind trial of 3 or 10 mg of melatonin compared with a placebo (NCT01874847). We included youth (ages 8–18 years) with PPCS at 4 to 6 weeks after mild traumatic brain injury. Those with significant medical or psychiatric histories or a previous concussion within the last 3 months were excluded. The primary outcome was change in the total youth self-reported Post-Concussion Symptom Inventory score measured after 28 days of treatment. Secondary outcomes included change in health-related quality of life, cognition, and sleep. RESULTS: Ninety-nine children (mean age: 13.8 years; SD = 2.6 years; 58% girls) were randomly assigned. Symptoms improved over time with a median Post-Concussion Symptom Inventory change score of –21 (95% confidence interval [CI]: –16 to –27). There was no significant effect of melatonin when compared with a placebo in the intention-to-treat analysis (3 mg melatonin, –2 [95% CI: –13 to 6]; 10 mg melatonin, 4 [95% CI: –7 to 14]). No significant group differences in secondary outcomes were observed. Side effects were mild and similar to the placebo. CONCLUSIONS: Children with PPCS had significant impairment in their quality of life. Seventy-eight percent demonstrated significant recovery between 1 and 3 months postinjury. This clinical trial does not support the use of melatonin for the treatment of pediatric PPCS. Full Article
wit Costs and Use for Children With Medical Complexity in a Care Management Program By pediatrics.aappublications.org Published On :: 2020-04-01T01:00:57-07:00 BACKGROUND AND OBJECTIVES: Children with medical complexity (CMC) comprise only 6% of the pediatric population, account for ~40% of pediatric health care spending, and provide an important opportunity for cost saving. Savings in this group can have an important impact on pediatric health care costs. The objective of this study was to assess the impact of a multicenter care management program on spending and use in CMC. DESIGN AND METHODS: We conducted a prospective cohort analysis of a population of 4530 CMC enrolled in a learning collaborative designed to improve care for CMC ages 0 to 21 years identified using 3M Clinical Risk Group categories 5b through 9. The primary outcome was total per-member per-year standardized spending; secondary outcomes included inpatient and emergency department (ED) spending and use. We used a 1:1 propensity score match to compare enrolled patients to eligible nonenrolled patients and statistical process control methods to analyze spending and usage rates. RESULTS: Comparison with the matched group showed a 4.6% (95% confidence interval [CI]: 1.9%–7.3%) decrease in total per-member per-year spending (P < .001), a 7.7% (95% CI: 1.2%–13.5%) decrease in inpatient spending (P = .04), and an 11.6% (95% CI: 3.9%–18.4%) decrease in ED spending (P = .04). Statistical process control analysis showed a decrease in hospitalization rate and ED visits. CONCLUSIONS: CMC enrolled in a learning collaborative showed significant decreases in total spending and a significant decrease in the number of hospitalizations and ED visits. Additional research is needed to determine more specific causal factors for the results and if these results are sustainable over time and replicable in other settings. Full Article
wit HIV Testing Among Adolescents With Acute Sexually Transmitted Infections By pediatrics.aappublications.org Published On :: 2020-04-01T01:00:57-07:00 BACKGROUND AND OBJECTIVES: Rates of sexually transmitted infections (STIs) have increased over the decade. Guidelines recommend HIV testing with incident STIs. Prevalence and factors associated with HIV testing in acute STIs are unknown in adolescents. Our objective was to determine the prevalence of completed HIV testing among adolescents with incident STIs and identify patient and health care factors associated with HIV testing. METHODS: Retrospective study of STI episodes (gonorrhea, Chlamydia, trichomoniasis, or syphilis) of adolescents between 13 and 24 years old from July 2014 to December 2017 in 2 urban primary care clinics. We performed mixed effects logistic regression modeling to identify patient and health care factors associated with HIV testing within 90 days of STI diagnosis. RESULTS: The 1313 participants contributed 1816 acute STI episodes. Mean age at STI diagnosis was 17.2 years (SD = 1.7), 75% of episodes occurred in females, and 97% occurred in African Americans. Only half (55%) of acute STI episodes had a completed HIV test. In the adjusted model, female sex, previous STIs, uninsured status, and confidential sexual health encounters were associated with decreased odds of HIV testing. Patients enrolled in primary care at the clinics, compared with those receiving sexual health care alone, and those with multipathogen STI diagnoses were more likely to have HIV testing. CONCLUSIONS: HIV testing rates among adolescents with acute STIs are suboptimal. Patient and health care factors were found to be associated with receipt of testing and should be considered in clinical practice. Full Article
wit Continuous Albuterol With Benzalkonium in Children Hospitalized With Severe Asthma By pediatrics.aappublications.org Published On :: 2020-04-01T01:00:57-07:00 BACKGROUND AND OBJECTIVES: The albuterol dropper bottle used to prepare solutions for continuous nebulization contains the preservative benzalkonium chloride (BAC). BAC, by itself, has been shown to cause bronchospasm. We hypothesized that BAC would decrease the therapeutic efficacy of albuterol in patients with acute asthma exacerbations. METHODS: We performed a retrospective cohort study comparing the clinical outcomes of patients <18 years of age receiving continuous nebulized albuterol with and without BAC. For the primary end point (duration of continuous albuterol nebulization), we compared the 2 groups with Kaplan-Meier estimate of survival curves, conducted a log-rank test of difference, and adjusted for baseline characteristics using multivariable Cox regression. A P value <.05 was considered significant. RESULTS: A total of 477 patients were included in the analysis (236 exposed to BAC and 241 controls). The duration of continuous nebulization was significantly longer in the BAC group than in the control group (median of 9 vs 6 hours; 15.7% required continuous nebulization compared to 5.8% of controls at 24 hours). The control group was 79% more likely to stop continuous nebulization at any particular point in time (hazard ratio 1.79; 95% confidence interval: 1.45 to 2.22; P < .001) and 43% more likely to stop additional respiratory support (hazard ratio 1.43; 95% confidence interval: 1.16 to 1.75; P < .001). CONCLUSIONS: BAC is a functional albuterol antagonist associated with a longer duration of continuous albuterol nebulization treatment and additional respiratory support, suggesting that preservative-free albuterol formulations are safer for use in continuous nebulization. Full Article
wit Digital Technology Is Gambling With Children's Minds By feedproxy.google.com Published On :: Tue, 13 Nov 2018 00:00:00 +0000 Writing, reading, focusing, and remembering have all been transformed in ways we don't yet fully understand, writes psychologist Elias Aboujaoude. Full Article Technology
wit Penn State Smeal MBA student unites community with fitness By news.psu.edu Published On :: Tue, 28 Apr 2020 09:39 -0400 When Penn State students were faced with the unprecedented challenge of remote learning for the remainder of the spring semester in response to COVID-19, Orlando Acevedo saw an opportunity to connect his community by organizing a 9-week fitness challenge. Full Article
wit Fin24.com | Debit order fraud: Consumers 'frustrated' and 'annoyed' with banks By www.fin24.com Published On :: Mon, 19 Nov 2018 21:58:33 +0200 Fin24 users speak of their frustrations with banks, calling for a crackdown on debit order fraud that sees payments they didn't authorise being deducted from their bank accounts each month. Full Article
wit Deals: Lenovo Flex 14, Dell Gaming Monitor, New Nintendo Switch By www.pcmag.com Published On :: Today you can save $120 on the Lenovo Flex 14 2-in-1 laptop. Also, the 24-inch Dell S2419HGF 1080p monitor dropped is now just $149.99. Finally, the new Nintendo Switch, featuring improved battery life, is now available. Full Article
wit 24 Hours With the Apollo Mood-Altering Wearable By www.pcmag.com Published On :: Developed by physicians and neuroscientists, Apollo isn't the sleekiest of wearables—you might mistake it for a court-ordered ankle bracelet—but it put a little pep in my step, and is an interesting talking point, if nothing else. Full Article
wit Lung Ultrasound in Children With COVID-19 By pediatrics.aappublications.org Published On :: 2020-04-21 Marco DeninaApr 21, 2020; 0:peds.2020-1157v1-e20201157Research Brief Full Article
wit Antibiotic Use and Outcomes in Children in the Emergency Department With Suspected Pneumonia By pediatrics.aappublications.org Published On :: 2020-04-01 Matthew J. LipshawApr 1, 2020; 145:e20193138-e20193138ARTICLES Full Article
wit Fin24.com | Organisation with an interest in financial literacy, invited to take part in Money Smart Week By www.fin24.com Published On :: Fri, 24 Jan 2020 15:45:55 +0200 Money Smart Week SA, a financial literacy campaign aimed at motivating and empowering South Africans to become more educated about their finances, is taking place from March 23 to 28, 2020. Full Article
wit Fin24.com | What to do with your 13th cheque? By www.fin24.com Published On :: Mon, 23 Dec 2019 15:54:37 +0200 The South African Payroll Association has been inundated with queries regarding their expected annual bonuses in December. Full Article
wit Fin24.com | Here's what SA financial experts would do with R10 000 in 2020 By www.fin24.com Published On :: Mon, 13 Jan 2020 15:34:59 +0200 Fin24 asked financial experts how they would grow R10 000 in the new year. Here's what they said. Full Article
wit Slade recognized with Jackson Lethbridge Tolerance Award By news.psu.edu Published On :: Thu, 09 Apr 2020 06:52 -0400 Ebonie Slade, a senior majoring in biobehavioral health at Penn State Greater Allegheny, is the recipient of the 2020 Jackson Lethbridge Tolerance Award. Full Article
wit Antiemetics in Children With Acute Gastroenteritis: A Meta-analysis By pediatrics.aappublications.org Published On :: 2020-04-01T01:00:57-07:00 CONTEXT: Several antiemetics have been used in children with acute gastroenteritis. However, there is still controversy over their use. OBJECTIVE: To determine the effectiveness and safety of antiemetics for controlling vomiting in children with acute gastroenteritis. DATA SOURCES: Medline, Embase, Cochrane Central Register of Controlled Trials, Cumulative Index to Nursing and Allied Health Literature, Latin America and the Caribbean Literature on Health Sciences, and gray literature, until December 2018. STUDY SELECTION: We selected randomized clinical trials comparing metoclopramide, ondansetron, domperidone, dexamethasone, dimenhydrinate, and granisetron. DATA EXTRACTION: Two reviewers independently screened abstracts and full texts, extracted the data, and assessed the risk of bias. We performed pairwise and network meta-analysis using the random-effects model. RESULTS: Twenty-four studies were included (3482 children). Ondansetron revealed the largest effect in comparison to placebo for cessation of vomiting (odds ratio = 0.28 [95% credible interval = 0.16 to 0.46]; quality of evidence: high) and for hospitalization (odds ratio = 2.93 [95% credible interval = 1.69 to 6.18]; quality of evidence: moderate). Ondansetron was the only intervention that reduced the need for intravenous rehydration and the number of vomiting episodes. When considering side effects, dimenhydrinate was the only intervention that was worse than placebo. LIMITATIONS: Most treatment comparisons had low- or very low–quality evidence, because of risk of biases and imprecise estimates. CONCLUSIONS: Ondansetron is the only intervention that revealed an effect on the cessation of vomiting, on preventing hospitalizations, and in reducing the need for intravenous rehydration. Ondansetron was also considered a safe intervention. Full Article
wit Nontraditional Pets Policy--Reaffirmed With Reference & Data Updates By pediatrics.aappublications.org Published On :: 2020-04-01T01:00:58-07:00 Full Article
wit Polio Policy: Reaffirmed With Reference and Data Updates By pediatrics.aappublications.org Published On :: 2020-04-01T01:00:58-07:00 Full Article
wit Neurodevelopmental Outcomes of Preterm Infants With Retinopathy of Prematurity by Treatment By pediatrics.aappublications.org Published On :: 2020-04-01T01:00:57-07:00 Full Article
wit Ditch That Headphone Splitter: How to Share Audio With Apple's AirPods By www.pcmag.com Published On :: With iOS 13.1 and iPadOS, Apple adds an Audio Sharing feature that lets you share with a friend what you're listening to on your Apple AirPods or select Beats headphones. Full Article
wit 3 Ways to Translate Conversations in Real Time With Google Assistant By www.pcmag.com Published On :: Google Translate is not the only app that can help you converse with someone speaking a different language. Here's how to translate real-time conversations with the Google Assistant. Full Article
wit How to Automate Your Life With Apple's iOS Shortcuts App By www.pcmag.com Published On :: Apple's Shortcuts app can quickly and easily run a host of tasks on your Apple Watch or iOS or iPadOS device. Here's how to create and use shortcuts for Siri. Full Article
wit How to View Files in Windows 10 Without Opening Them By www.pcmag.com Published On :: Don’t like to wait for programs to boot up when you’re looking for a specific document? With the right tools, you can preview a variety of files in Windows 10 without opening their applications. Full Article
wit Apple Refreshes iPod Touch With Better Camera, Chip By www.pcmag.com Published On :: Apple quietly revealed new iPods today with new colors and better specs. Full Article
wit Tidal's iPod? Hands On With Echobox's Flask-Shaped Explorer X1 By www.pcmag.com Published On :: A new high-res audio player looks like a wooden flask and has a tie-up with Tidal. Full Article
wit How to Capture Important Data With Scanning and OCR Apps By www.pcmag.com Published On :: With the best scanning and OCR apps, you can save whiteboard text, business cards, and important documents so that you can not only read them, but also edit them. Full Article
wit Deals: Apple AirPods, Dell Laptops, Nintendo Switch By www.pcmag.com Published On :: Save on the second-generation Apple AirPods with the wireless charging case, Logitech gaming gear, Dell laptops, the Nintendo Switch, and more today. Full Article
wit Microsoft Enhances OneDrive With a Personal Vault By www.pcmag.com Published On :: Alongside a new protected area of storage, OneDrive and Office 365 storage options are changing for the better. Full Article
wit Get a Free Echo Dot With Any Toshiba, Insignia Fire TV Edition By www.pcmag.com Published On :: That free Echo Dot will let you launch apps, search for titles, and switch inputs on your TV with just your voice. Full Article
wit LG TV Morphs From Flat Screen to Curved With Press of a Button By www.pcmag.com Published On :: At CES, LG Display is showing off a 65-inch concept TV that can bend at the edges, allowing it to switch from a flat-screen display to a curved one in about five seconds. The company also put a bendable OLED on a foldable tablet/laptop. Full Article
wit Deals: Vizio M-Series 4K TV, XPS 15 With 4K OLED, Roborock S5 By www.pcmag.com Published On :: The 55-inch Vizio M-Series 4K TV is just $358, $40 less than its Black Friday price. Plus, Dell's XPS 15 laptop is $350 off and the Roborock S5 robot vacuum is $200 off. Full Article
wit Warren: 'We Are Failing on Our Country's Promise' to Children With Disabilities By feedproxy.google.com Published On :: Thu, 02 Jan 2020 00:00:00 +0000 A new plan from Democratic presidential candidate and former special educator Elizabeth Warren touches on some glaring issues in special education: graduation disparities, hard-to-access school buildings, and discipline practices that disproportionately affect black, Latino, and Native American stud Full Article Specialeducation
wit School Districts Struggle With Special Education Costs By feedproxy.google.com Published On :: Wed, 22 Jan 2020 00:00:00 +0000 For decades, special education advocates have urged the federal government to "fully fund" the Individuals with Disabilities Education Act. Here are some examples 'ripped from the headlines' of how the funding gap is affecting school districts. Full Article Specialeducation
wit Principals Say They Need Help to Support Students With Disabilities By feedproxy.google.com Published On :: Thu, 13 Feb 2020 00:00:00 +0000 The need for materials, training, guidance from district administrators, and access to staff with expertise in serving students with disabilities is especially acute in schools that serve primarily black and Latino students, a new survey finds. Full Article Specialeducation
wit 'Are We Going to Get Ourselves in Trouble?': Districts Struggle With Special Education By feedproxy.google.com Published On :: Thu, 19 Mar 2020 00:00:00 +0000 With the coronavirus pandemic pressing tens of thousands of the nation's school districts into extended closures, education administrators across the nation are wrestling with a complex and legalistic problem: how to keep services flowing for students with disabilities. Full Article Specialeducation
wit FDA Bans Use of Shock Therapy at School for Students With Special Needs By feedproxy.google.com Published On :: Thu, 05 Mar 2020 00:00:00 +0000 The FDA estimates that between 45 and 50 students at a Massachusetts school for students with autism, emotional disturbances, and intellectual disabilities are subjected to electrical shocks through electrodes attached to their skin. Full Article Specialeducation
wit Fierce Debate as DeVos Weighs Schools' Obligations to Students With Disabilities By feedproxy.google.com Published On :: Tue, 31 Mar 2020 00:00:00 +0000 Amid coronavirus-related school closures, advocates worry Education Secretary Betsy DeVos may waive requirements of special education law if Congress signs off. Schools say it's difficult to meet some requirements during the pandemic. Full Article Specialeducation
wit Going Public with Research to Drive Engagement By feedproxy.google.com Published On :: Thu, 24 May 2018 00:00:00 +0000 How a public research event can bring education stakeholders together to discuss important early education issues. Full Article Research
wit Teachers of Students With Behavior Problems Want Help Finding Evidence-Based Tools By feedproxy.google.com Published On :: Tue, 15 May 2018 00:00:00 +0000 A survey of educators around the country found that many reported looking up interventions on their own, when they really wanted more formal training, a survey found. Full Article Research
wit One in 5 Students With Significant ADHD Gets No School-Based Help, Study Finds By feedproxy.google.com Published On :: Wed, 06 Mar 2019 00:00:00 +0000 Reports from the parents of nearly 2,500 children and youths with attention deficit hyperactivity disorder found a gap between students with the most severe symptoms and those who get any school-based interventions. Full Article Research
wit Language of Early- and Later-identified Children With Hearing Loss By pediatrics.aappublications.org Published On :: 1998-11-01 Christine Yoshinaga-ItanoNov 1, 1998; 102:1161-1171ARTICLES Full Article
wit An Epidemiologic Profile of Children With Special Health Care Needs By pediatrics.aappublications.org Published On :: 1998-07-01 Paul W. NewacheckJul 1, 1998; 102:117-123ARTICLES Full Article
wit Prolonged Duration of Initial Empirical Antibiotic Treatment Is Associated With Increased Rates of Necrotizing Enterocolitis and Death for Extremely Low Birth Weight Infants By pediatrics.aappublications.org Published On :: 2009-01-01 C. Michael CottenJan 1, 2009; 123:58-66ARTICLES Full Article
wit Children With Complex Chronic Conditions in Inpatient Hospital Settings in the United States By pediatrics.aappublications.org Published On :: 2010-10-01 Tamara D. SimonOct 1, 2010; 126:647-655ARTICLES Full Article
wit A New Definition of Children With Special Health Care Needs By pediatrics.aappublications.org Published On :: 1998-07-01 Merle McPhersonJul 1, 1998; 102:137-139COMMENTARY Full Article
wit England presented with Maurice Burlaz Trophy By www.uefa.com Published On :: Wed, 06 Dec 2017 08:01:00 GMT England won the 2017 Maurice Burlaz Trophy, the prize awarded to the nation that achieved the best results in UEFA's men's youth competitions over the previous two seasons. Full Article general
wit Blood Pressure Responses to Psychosocial Stress in Young Adults With Very Low Birth Weight: Helsinki Study of Very Low Birth Weight Adults By pediatrics.aappublications.org Published On :: 2009-01-26 Young adults born prematurely with very low birth weight (≤1500 g) have higher blood pressure than do their counterparts born at term. We tested whether they also have higher blood pressure reactivity to psychosocial stress, which may be a more-specific predictor of long-term cardiovascular morbidity. Systolic and diastolic blood pressure levels for 44 very low birth weight adults (mean age: 23.1 years; SD: 2.3 years) and 37 control subjects (mean age: 23.6 years; SD: 2.0 years) were measured through noninvasive finger photoplethysmography during a standardized psychosocial stress challenge (Trier Social Stress Test). Baseline and task values and their difference (ie, reactivity) served as outcome variables. In comparison with the control group, the very low birth weight group had 7.9 mm Hg higher diastolic blood pressure during the task and 4.8 mm Hg higher diastolic reactivity, with adjustment for gender and age, height, and BMI at testing. A similar trend was seen for systolic blood pressure during the baseline period and the task, but the group differences were not statistically significant. Our results indicate that very low birth weight is associated with elevated blood pressure reactivity to psychosocial stress and, therefore, may increase the risk of cardiovascular morbidity. Full Article
wit Penn State Harrisburg recognizes staff with 25 years of service By news.psu.edu Published On :: Wed, 22 Apr 2020 12:00 -0400 Penn State Harrisburg this spring recognized staff members who have served the college for 25 years. Full Article
wit Penn State Harrisburg honors student-athletes with virtual awards ceremony By news.psu.edu Published On :: Tue, 05 May 2020 11:03 -0400 Penn State Harrisburg Intercollegiate Athletics recently honored the athletic, academic, and community achievements of its student-athletes during the 2020 Student-Athlete Award Ceremony video presentation. Full Article
wit Future Teachers Are Unfamiliar With Basic 'Learning Science,' Report Finds By feedproxy.google.com Published On :: Wed, 11 Mar 2020 00:00:00 +0000 "There's a science of learning, and ... there's not a single teacher who couldn't benefit, I think, from knowing these principles," said the executive director of Deans for Impact, a group of education school leaders. Full Article Teacherpreparation