Experts say the vulnerability of health systems in Eastern Europe spurred leaders into decisive action while governments in the west felt a 'greater sense of complacency'.

A new study from San Raffaele Hospital in Milan, Italy, found that 72% of 29 coronavirus patients given anakinra, an arthritis drug, had improved respiratory health and markers of inflammation.

Researchers from Australia compared 13 studies of numbers of people killed by the coronavirus and suggested a 0.75 per cent death rate, and a range of 0.45-1.01 was reasonable.

SIR CLIVE WOODWARD: England missed out on the scoreboard in Cardiff - and they missed a huge learning opportunity. What did they gain from the match? Not much. What did they learn? Not much.

The Rugby World Cup is just round the corner and Sportsmail has everything you need to know. SIR CLIVE WOODWARD has the lowdown on every team in the tournament in Japan.

SIR CLIVE WOODWARD - WORLD CUP WINNING COACH: The World Cup is up and running and my only concern about England against Tonga is evidence of discipline.

SIR CLIVE WOODWARD: I can't imagine England have ever played better on the biggest stage. I felt a huge surge of pride watching this team and admiration for how clever and skilled they were.

SIR CLIVE WOODWARD: It is very seldom I tip against England, if ever, as I just never see them losing at rugby. But I must confess I make France the favourites in Paris.

SIR CLIVE WOODWARD: England have taken Ireland to the cleaners twice in the past 12 months, but only one of those victories counted for a bean and that was in Dublin 12 months ago.

SIR CLIVE WOODWARD: It might have been a little subdued before the match but we should have known England and Wales would provide some action to perk us up. The 33-30 win for England was all action.

SIR CLIVE WOODWARD: When Bill Beaumont clocks back on Monday morning, it would be worth remembering that, although the official tally says 28-23, he actually won by only one vote.

Myriad Polos have come and gone over the years, with 12 million cars sold so far, including past World Car of the Year winners

M-agnificent! M-azing! M-ammoth! M-ega! M-believable! That’s five Ms for starters. In fact, let’s dispense with any cod nonsense and declare this car an absolute superstar from the get-go

From a design point of view, the shell (still) looks like a pregnant, stretched 911-shaped whale, which I (still) can’t believe anyone finds attractive – but I know they do

For the entire time I had this car, my family knew where I was at every moment due to the bright yellow colour of the Suzuki Swift.

The new 911 GT2 RS is a vision to look at, a dream to drive, heaven to smell and irresistible to the touch – in short, it’s the best version of everything it could possibly be

Well, look what we have here… If it isn’t another mid-size SUV crossover for us all to get excited about. Which isn’t difficult – from a styling point at least (after which don’t hold your breath)

The Vantage’s new super-streamlined looks and all-round body shape are simply to die for. In profile the car, even at a standstill, looks like it’s flying through the air

First off, though, let’s get the downside out of the way. Dear VW, why oh why didn’t you make your latest GTi incarnation more exciting to look at?

The Champions League returned with a bang this week as Borussia Dortmund, Atletico Madrid and RB Leipzig took huge steps towards three big upsets.

Sportsmail looks at whether Chelsea or Tottenham are better equipped to secure a Champions League spot ahead of their meeting at Stamford Bridge on Staurday afteroon.

OLIVER HOLT AT STAMFORD BRIDGE: Any Spurs fans - or players - expecting a rallying cry after a significant setback like this would have been sorely disappointed.

There was a glint in Pep Guardiola's eye as he talked about Real Madrid, as European football's most influential coach gets ready to tackle its ultimate winning machine.

The Premier League once again treated spectators to twists and turns galore, and here are 10 things we learned from all the action this weekend.

The forward flew back to his homeland last week for an operation in Seoul on his broken right arm, an injury Jose Mourinho fears could keep him out for the rest of the season.

THE NUMBERS GAME - JORDAN SEWARD: Dele Alli is statistically Tottenham's biggest goal threat right now with Kane and Son injured. Mourinho needs him firing ahead of important run of games.

EXCLUSIVE INTERVIEW BY IAN LADYMAN: The latter half of this season feels a little bit like the second coming of a player who lost his way a little bit in the final days of Mauricio Pochettino.

With Tottenham losing 3-2 to Wolves on Sunday in the Premier League and having no out-and-out strikers at his disposal, Mourinho only decided to call on the 18-year-old in injury-time.

IAN LADYMAN: Common sense gives Lampard at least one more season. Common sense says a young, bright manager is given opportunity to plan properly in a way that few of his predecessors were.

Jose Mourinho is set to make a summer bid for Manchester United defender Chris Smalling, according to reports in Italy, as Roma haggle with United over a permanent deal for the defender.

Toby Alderweireld has described the 'strange' time around the sacking of Mauricio Pochettino at Tottenham and Jose Mourinho's ensuing arrival as manager. 

Tottenham host Norwich and Sheffield Wednesday play Man City tonight in the FA Cup fifth round. Sportsmail's KIERAN JACKSON will provide live commentary of the action and the quarter-final draw.

MATT BARLOW AT THE TOTTENHAM HOTSPUR STADIUM: Norwich have booked their place in the quarter-finals of the FA Cup after beating Jose Mourinho's Tottenham on penalties.

Eric Dier's decision to cross the ancient boundary and storm the West Stand at White Hart Lane was not the first error of judgment by a Spurs player on the night they crashed out of the FA Cup.

Gawping bystanders with their phones are surely the most dismal part of the scene. As someone sagely observed on Wednesday night, Stanley Kubrick didn't have that many cameramen for Spartacus.

It all went wrong off the pitch for Spurs on Wednesday but it's not going well on it either. Eric Dier made headlines, although the display was not much to write home about.

Jose Mourinho will have no hesitation about fielding Eric Dier against Burnley on Saturday after making a passionate defence of the Englishman in the wake of his row with a fan.

He has the self-awareness to know he sounds like a broken record, but the deepening mystery is whether Jose Mourinho still has the managerial tools to fix a broken team.

Spurs boss Jose Mourinho is angry with Tanguy Ndombele, Eric Dier is angry with fans and Spurs players were angry with each other in a heated half-time inquest at Turf Moor on Saturday.

Ahead of Spurs' second-leg against Red Bull Leipzig tonight, an omen Spurs fans won't want to hear: Jose Mourinho has never won a Champions League knockout tie after losing the first-leg at home.

The dark clouds are looming over Tottenham after four defeat in their last five. But victory over RB Leipzig and Champions League progression would be a huge boost.

There was no heart-stopping comeback for Tottenham in Leipzig, no second-half resurrection. They lost away as they did at home, just by more as they tumbled out of the Champions League.

MATT BARLOW AT THE RED BULL ARENA: As Tottenham faltered, the very same Mourinho who carved his reputation on defensive organisation could only watch on with a puzzled expression.

MATT BARLOW IN LEIPZIG: Spurs crashed out of the Champions League with a 4-0 aggregate defeat against RB Leipzig just seven days after they were dumped out of the FA Cup.

MATT BARLOW AT THE RED BULL ARENA: Jose Mourinho's side were beaten 4-0 on aggregate and Alli admitted they lacked 'maturity and 'fight' and that their 'mentality' was not 'strong enough'.

MATT BARLOW AT THE RED BULL ARENA: Jose Mourinho admits his beleaguered Tottenham team faces an uphill struggle to be back in the Champions League next season.

With defeat at Leipzig ending Tottenham's hopes of a trophy this season, Sportsmail looks at six things Mourinho must learn if he is to make a more successful time of it next season.

Tottenham still remain interested in Valencia midfielder Geoffrey Kondogbia as Jose Mourinho is looking to strengthen his squad this summer.

David Ginola believes Mauricio Pochettino was doomed after guiding Tottenham into last year's Champions League final and the club's remarkable run is the reason why Jose Mourinho is struggling.

EXCLUSIVE BY KIERAN GILL: Amazon Prime's cameras are continuing to film at the Tottenham Hotspur training ground amid the coronavirus pandemic.