li The Rising Star Scaffolding Guide: Supporting Young Children’s Early Spelling Skills By www.readingrockets.org Published On :: Fri, 16 Dec 2022 13:19:12 EST Encouraging pre-kindergarten children to write affords teachers the opportunity to provide scaffolds to improve spelling development. Teachers, however, tend to provide more support than necessary to guide children's early spelling, which may stifle children's opportunities to engage in important thinking that helps them to grow in their literacy knowledge. Full Article
li Frontpage SlideShow By www.joomlaworks.net Published On :: Thu, 03 Mar 2022 21:04:59 +0200 Now fully responsive & Joomla 1.5 - 3.x compatible! Frontpage SlideShow is the easiest & most eye-catching way to display your featured articles or products in your Joomla website. It creates an uber cool slideshow with text snippets laying on top of images, in a variety of templates and combined effects. Frontpage SlideShow allows you to create multiple slideshows within your Joomla website (in different pages or even on the same page), comes with 8 uniquely styled templates, a powerful jQuery based slideshow engine with crossfade & carousel based transitions, text effects, statistics and can retrieve content automatically from Joomla articles/menus, K2 items and Virtuemart/HikaShop products! Frontpage SlideShow is a pure CSS & JavaScript based slideshow system, which means it's dead simple to customize and it's both SEO and tablet/mobile friendly (in iOS, Android or Windows 8 smartphones & tablets). And don't worry about how you'll manage your slideshows. Unlike other expensive/copycat implementations, Frontpage Slideshow has a dedicated Joomla backend component which you use to effortlessly manage your slideshows. Easy and fast. Moreover, it now natively supports content fetching from K2 and the most popular e-commerce components for Joomla: Virtuemart (versions 2.x & 3.x) and HikaShop. That means you quickly make up your slides just by selecting the source (e.g. a K2 item) and Frontpage Slideshow will fetch in a snap the title, description text and associated image! FEATURES Fully compatible with Joomla 1.5 - 3.x Lightweight & frontend optimized slideshow engine, based on jQuery, offering crossfade & carousel transition effects between slides, lava-lamp style navigation, progress bar and text transition effects. That means you have 24 different effect combinations to use! 9 slideshow templates to get you started. Customizing them is very easy as all fonts, font-sizes, colors etc. are controlled by CSS. Building your own is a joy if you know your way around with MVC templating in Joomla. Responsive as of v3.10. The slide creation process is dead simple to use through guided steps. Drag and drop slide re-ordering (per category) in the backend. Integration with Joomla articles and the most popular Joomla content extensions like K2, Virtuemart (2.x & 3.x) & HikaShop. That means Frontpage Slideshow can import the title, text, link and associated image from such components with a single clicks. For example, if you want to create a slide from a K2 item, all you have to do is select that K2 item and Frontpage Slideshow will automatically populate all slide fields, which you are free of course to edit as you wish! You can now display your slideshows either via the module (or multiple module copies) or via the new component view. That means you can create a direct menu link to a specific slideshow, so you can e.g. assign a slideshow to your homepage, without messing with module positions and funky module display conditions. This option is ideal for portfolio based websites that want to assign slideshows directly to Joomla menu items. Multiple slideshows in your Joomla website, even on the same page (thanks to new slideshow engine) - so you can have a slideshow fetched in the component region and an other in a module or in combinations you define. Better slide image uploading using ajax (which means better previewing) and better slide image management (similar to K2's), with multiple copies of your original image created for better performance. And we got some cool new templates to show in the near future using these different size images... Statistics! Frontpage Slideshow will now track (by default) all slideshow clicks and create beautiful statistics graphs in the backend, so you can visually see which are your most popular slides in various timeframes. Using Frontpage Slideshow to promote products? Now you can now which products draw your customers attention more! Statistics can of course be disabled at any time if you prefer SEO over click tracking. Better server-side performance compared to version 2.x. A new caching layer for the module and the new slideshow content prefetching mechanism, which reduces the queries needed to retrieve slide content from third-party extensions (K2, Virtuemart & HikaShop). In high traffic or high content volume Joomla websites, this translates to significantly better performance. Better image compression on both desktop and mobile browsers with the integration of a 3rd party web service. This can lead to up to 50% image size reduction and mobile optimized serving of images when your site is viewed in mobile browsers on iPhone/iPad/Android etc. Full ACL integration with Joomla 2.5+. New version/update notification in Joomla 2.5+. The component's user interface is very clean and easy to learn. It consists of only 2 areas to edit: your slides and your categories (slideshows). Additionally, the styling/customization of each slideshow is entirely HTML/CSS based. You have full control over the layout of the slideshow and you can easily style it to suit your needs. No other website will ever share the same looks as yours! As with all our Joomla extensions, Frontpage Slideshow uses MVC template overrides - so you can modify existing templates or create your own from scratch without a) hacking core extension code and b) worrying about future updates breaking up your changes. Frontpage Slideshow has been successfully tested in all major browsers. The prebundled slideshow templates are fully compatible with Firefox, Chrome, Safari, Opera, Edge and Internet Explorer version 7 and above. SCREENSHOTS Backend interface screenshots taken from Joomla 1.5 (which is nearly identical to Joomla 2.5) & Joomla 3.x. Frontpage Slideshow uses the Joomla backend design guidelines so it will match the design of all these Joomla versions, from 1.5 to 3.x.{gallery}galleries/FPSS_3.0.0_screenshots{/gallery} Full Article Commercial
li Discover Something New at Home this Holiday Season By www.gadling.com Published On :: Mon, 25 Nov 2013 12:15:00 EST Filed under: Food and Drink, North America, United StatesTraveling "home" this holiday season? Don't fall into your old routine. Your high school hangout may be an easy go-to, but if you don't live there anymore there's a good chance you're missing out on some great new local spots. (Plus, be honest: you already know what all your classmates are up to from Facebook.) We turned to local writers to help you rediscover your hometown over Thanksgiving and the winter holidays. Each city guide features a great new restaurant to try while you're in town, a cool neighborhood that wasn't on the radar last year or a store where you can pick up a keepsake to bring your old home back to your new home. We'll also catch you up to speed on the hot topics of conversation in each city, so you'll come back savvy enough to join the local sports banter or eat your holiday weight in Cronuts. Click your city below to learn what's new since the last time you went home:Continue reading Discover Something New at Home this Holiday SeasonDiscover Something New at Home this Holiday Season originally appeared on Gadling on Mon, 25 Nov 2013 12:15:00 EST. Please see our terms for use of feeds.Permalink | Email this | Comments Full Article Discover Something New at Home holiday travel
li Will You Be a Horrible Restaurant Customer This Holiday Season? By www.gadling.com Published On :: Wed, 27 Nov 2013 16:31:00 EST Filed under: Food and Drink, North America, Canada, United StatesGetty Images So you've finished your Thanksgiving dinner and you're finally sick of turkey leftovers. It's time to get out there and hit the great new restaurant that just opened in your hometown or wherever you're spending the holidays. (FYI: Aol Travel knows the hot restaurants in cities around the U.S.) Wherever you go, remember that there are appropriate ways to behave. And there are horrible ways to behave, as highlighted in this Montreal Gazette story by two Montreal-area restaurant servers. Among other things, they urge:Continue reading Will You Be a Horrible Restaurant Customer This Holiday Season?Will You Be a Horrible Restaurant Customer This Holiday Season? originally appeared on Gadling on Wed, 27 Nov 2013 16:31:00 EST. Please see our terms for use of feeds.Permalink | Email this | Comments Full Article restaurants thanksgiving
li And the Winner of Sound of Music Live Is... By www.gadling.com Published On :: Fri, 06 Dec 2013 14:30:00 EST Filed under: Europe, Austria, NewsJasper180969 via Flickr Last night's live production of The Sound of Music on NBC got more flak than Maria did for being an unsolvable problem nun. The acting was bad, the costumes St. Pauli-esque and the mountains... gasp! They were fake! No. It's all wrong. Those fake mountains.The captain is a vampire. And there's only one Julie Andrews. Two minutes was enough #SoundofMusic - Paola (@Paopalinaa) December 6, 2013 But there was one winner in last night's performance: the city of Salzburg, Austria. Home of the Von Trapps, setting of the original movie and now site of thousands of Edelweiss-blasting tour buses and gazebo-worshipping 16-going-on-17-year-olds, Salzburg enjoyed a flurry of love last night.Continue reading And the Winner of Sound of Music Live Is...And the Winner of Sound of Music Live Is... originally appeared on Gadling on Fri, 06 Dec 2013 14:30:00 EST. Please see our terms for use of feeds.Permalink | Email this | Comments Full Article salzburg sound of music
li Vineyard and Zipline Trends Collide at the Pinot Express By www.gadling.com Published On :: Wed, 11 Dec 2013 16:54:00 EST Filed under: Food and Drink, North America, United States Chris Leschinsky Vineyards and ziplines have long been used to attract tourist dollars for destinations that, well, could use a little help: Regardless of the area's suitability for growing grapes, plop down a vineyard or winery and travelers will come for a taste and buy a sympathy bottle (pro tip: go for the ice wine as it's harder to mess up) Ski resorts looking to attract off-season dollars or stale attractions looking to draw media coverage and visitors hook up a zipline So really, the 1,800-foot Pinot Express zipline at Margarita Adventures, which debuted recently at the Santa Margarita Ranch in the Paso Robles wine country on California's Central Coast, is the travel industry's destiny.Continue reading Vineyard and Zipline Trends Collide at the Pinot ExpressVineyard and Zipline Trends Collide at the Pinot Express originally appeared on Gadling on Wed, 11 Dec 2013 16:54:00 EST. Please see our terms for use of feeds.Permalink | Email this | Comments Full Article California Paso Robles Pinot Express Santa Margarita Santa Margarita Ranch Zipline
li Sorry Indianapolis, You're No Longer the Sole Location Offering TSA PreCheck Enrollment Background Checks By www.gadling.com Published On :: Mon, 16 Dec 2013 15:07:00 EST Filed under: North America, United States Getty Two weeks ago, the Transportation Security Administration announced that it would began allowing travelers to apply for its PreCheck program, "an expedited screening process" through airport security. Curiously though, the only airport in the country where travelers could complete the program's required background interview was Indianapolis International Airport. That changed today when TSA opened three enrollment centers in the Washington, DC area. Interestingly, none of them are at DC-area airports. Nor are any of them in DC itself.Continue reading Sorry Indianapolis, You're No Longer the Sole Location Offering TSA PreCheck Enrollment Background ChecksSorry Indianapolis, You're No Longer the Sole Location Offering TSA PreCheck Enrollment Background Checks originally appeared on Gadling on Mon, 16 Dec 2013 15:07:00 EST. Please see our terms for use of feeds.Permalink | Email this | Comments Full Article Alexandria PreCheck Transportation Security Administration TSA Virginia Washington DC
li London, Rome, Paris Top TripAdvisor's Most-Reviewed Cities List By www.gadling.com Published On :: Tue, 17 Dec 2013 14:11:00 EST Filed under: Europe, North America, France, United Kingdom, United States Alamy The litany of year-end travel-related lists continues. Today, it's TripAdvisor, which unveiled its most reviewed cities. Leading the way: London, Rome and Paris, according to the Telegraph. The top U.S city was New York, which ranked fourth overall -- a stunning blow for American exceptionalism.Continue reading London, Rome, Paris Top TripAdvisor's Most-Reviewed Cities ListLondon, Rome, Paris Top TripAdvisor's Most-Reviewed Cities List originally appeared on Gadling on Tue, 17 Dec 2013 14:11:00 EST. Please see our terms for use of feeds.Permalink | Email this | Comments Full Article Las Vegas London New York New York City Paris Rome The Telgraph TripAdvisor
li Discover Something New at Home this Holiday Season By www.gadling.com Published On :: Wed, 18 Dec 2013 11:04:00 EST Filed under: Food and Drink, North America, United StatesTraveling "home" this holiday season? Don't fall into your old routine. Your high school hangout may be an easy go-to, but if you don't live there anymore there's a good chance you're missing out on some great new local spots. (Plus, be honest: you already know what all your classmates are up to from Facebook.) AOL Travel turned to local writers to help you rediscover your hometown over the winter holidays. Each city guide features a great new restaurant to try while you're in town, a cool neighborhood that wasn't on the radar last year or a store where you can pick up a keepsake to bring your old home back to your new home. AOL Travel also will catch you up to speed on the hot topics of conversation in each city, so you'll come back savvy enough to join the local sports banter or eat your holiday weight in Cronuts. Click your city below to learn what's new since the last time you went home:Continue reading Discover Something New at Home this Holiday SeasonDiscover Something New at Home this Holiday Season originally appeared on Gadling on Wed, 18 Dec 2013 11:04:00 EST. Please see our terms for use of feeds.Permalink | Email this | Comments Full Article
li Another Boeing 787 Dreamliner Has a Battery Problem By www.gadling.com Published On :: Tue, 14 Jan 2014 14:57:00 EST Filed under: Asia, Japan, Airlines, News Getty Images Japan Airlines grounded a Boeing 787 Dreamliner aircraft today "after detecting smoke or gases that may have come from faults with the main battery," according to the BBC. Last year, all 787s were grounded for three months, CBS reports, after a "fire in a lithium ion battery aboard a Japan Airlines 787 parked at Boston's Logan International Airport. That was followed nine days later by another battery incident that forced an emergency landing in Japan by an All Nippon Airways 787.Continue reading Another Boeing 787 Dreamliner Has a Battery ProblemAnother Boeing 787 Dreamliner Has a Battery Problem originally appeared on Gadling on Tue, 14 Jan 2014 14:57:00 EST. Please see our terms for use of feeds.Permalink | Email this | Comments Full Article BBC Boeing Boeing 787 Boeing 787 Dreamliner CBS ithium ion battery Japan Airlines Los Angeles Times Narita International Airport
li $7.2 Million Cash Found in Suitcases at Panama City Airport By www.gadling.com Published On :: Fri, 17 Jan 2014 17:04:00 EST Filed under: Panama, Airports, News, Central America Newsy Travel tip: If you're trying to smuggle cash into Panama, start using the train. Three Honduran men were arrested at Panama City's international airport after police found $7.2 million, mostly in $100 bills, in secret compartments in eight pieces of luggage. According to this video from Newsy (Newsy? Really? Really.), officials in Panama believe the money was connected to a drug cartel. Thirty-two officers and airport security staffers have been suspended as a result of the find.Continue reading $7.2 Million Cash Found in Suitcases at Panama City Airport$7.2 Million Cash Found in Suitcases at Panama City Airport originally appeared on Gadling on Fri, 17 Jan 2014 17:04:00 EST. Please see our terms for use of feeds.Permalink | Email this | Comments Full Article Luggage Newsy Panama City Smuggling
li Skift Acquires Gadling Travel From AOL By www.gadling.com Published On :: Thu, 12 Jun 2014 09:04:00 EST Filed under: Business, Talking Travel The Skift team -- now the Gadling team, too -- in Iceland this May. It's been quiet here for a while, but that's about to change. I'm happy to announce that Gadling is becoming part of the Skift family. You may have read about us in this Gadling interview when we launched nearly two years ago. Since then, Skift has become the largest travel industry news and information site in the world. Over the short two years of our existence, our brand has become the lingo in travel. As AOL has decided to focus on MapQuest as the center of its travel strategy, it wanted to find a good home for Gadling. That's us. Additionally, we're excited to announce a partnership with MapQuest, leveraging their global mapping platform and collaborating on relevant content. MapQuest serves 40 million multi-platform users every month, providing directions, local search and discovery, and mapping solutions for everyday needs. "We love what Skift is doing and believe their work leads the market. We look forward to working with Skift to bring great travel content and services to consumers and the travel industry," said Brian McMahon, general manager of MapQuest. We will take over Gadling's extensive online presence, from the website to its popular social media feeds, and continue to build it as an inspiration and news-you-can-use companion to the business-focused Skift site. We've long been fans of Gadling's style of travel and writing and we're happy to be stepping in now. Gadling will stay as is for a short bit while we tinker behind the scenes. Stay tuned, we're just getting started. Share your email, and we'll let you know when Gadling relaunches. Email Skift UpdatesSkift Updates Daily NewsletterBusiness Traveler Newsletter (sent Mondays and Thursdays)SkiftIQGadling Do Not Fill This Out Skift Acquires Gadling Travel From AOL originally appeared on Gadling on Thu, 12 Jun 2014 09:04:00 EST. Please see our terms for use of feeds.Permalink | Email this | Comments Full Article
li Donald Trump’s policies risk making the US dollar a source of global instability By www.chathamhouse.org Published On :: Wed, 13 Nov 2024 14:15:28 +0000 Donald Trump’s policies risk making the US dollar a source of global instability Expert comment LToremark 13 November 2024 Although Trump favours a weaker exchange rate, his policies are likely to have the opposite effect. The risk is that the US dollar could become too strong, which is bad news for the global economy. President-elect Donald Trump has a dollar problem. In recent months he has shown a clear preference for a weaker exchange rate to support the competitiveness of US exports and help reduce the US trade deficit. And yet, as the market has sensed since the US election, the much more likely outcome is that his policies end up strengthening the greenback. The risk is that the US dollar – which is expensive already – becomes more obviously overvalued, and this could increase the risk of global financial instability. The risk is that the US dollar – which is expensive already – becomes more obviously overvalued, and this could increase the risk of global financial instability. The dollar has been on a rollercoaster ride in the past few decades. From 2002 until 2011, for example, the dollar weakened by around 30 per cent in inflation-adjusted, trade-weighted terms, according to BIS data. Yet in the years since 2011, the dollar has strengthened and is now at a more appreciated level than at any time since 1985.What shapes this rollercoaster, broadly speaking, is the global balance of economic vitality: when the US economy gains momentum relative to the rest of the world, the dollar tends to strengthen; and vice versa. After China joined the WTO in 2001, the balance of economic vitality shifted decisively away from the US, in favour of China and other emerging economies. This was the decade of the commodity boom: the longest, biggest peacetime increase in commodity prices in nearly 200 years during which a sustained surge in China’s economy supported GDP growth across the developing world. The dollar weakened as a result. Related content US dollar dominance is both a cause and a consequence of US power But after 2011, a combination of factors – including the eurozone crisis and its aftermath, together with the sagging of the Chinese economy – tipped the balance of economic vitality back in favour of the US. The dollar strengthened once again.And since both the European and Chinese economies remain very fragile, the balance of economic vitality seems likely to keep favouring the US dollar.Two more considerations also point to a stronger US dollar under a second Trump administration.The first is the exchange rate implications of Donald Trump’s proposed tariffs on imports. When the US imposes tariffs on a trading partner, the foreign exchange market tends to sell that trading partner’s currency, forcing it to weaken to offset the dollar-price increase induced by the tariff. This helps explain why the Chinese renminbi depreciated by some 10 per cent in 2018 after Trump began imposing trade restrictions on China in January of that year. More widespread tariffs on a whole range of US trading partners should therefore strengthen the dollar more broadly.A stronger dollar should also result from the macroeconomic framework Trump seems likely to deliver. He will certainly want to extend his 2017 tax cuts beyond 2025 when they are currently due to expire, so a more sustained loosening of US fiscal policy seems likely. Since boosting the US economy will create inflationary pressure, the market will expect interest rates to end up higher than they might otherwise be. The resulting combination of looser fiscal and tighter monetary policy tends to be a stronger currency. Related content Members’ question time: Is this the end of dollar dominance? The dollar probably has a fair amount of room to keep going up, since it is not obviously overvalued just yet. The US current account deficit – the broadest measure of a country’s trade deficit, and a rough but useful measure of financial vulnerability – was a little over 3 per cent of GDP last year. This is around half the level it reached in 2006, just before the 2008 global financial crisis, meaning the risks arising from an overvalued dollar may be for the latter part of Trump’s second presidency.A strengthening dollar is also not great news for the rest of the world economy. A strong dollar tends to depress global trade growth, restrict developing countries’ access to international capital markets, and make it more difficult for countries whose currencies will be weakening to keep inflation under control.If and when the dollar becomes unsustainably expensive, a further problem will present itself: how to deal with an overvalued currency without risking a lot of financial dislocation.This problem last occurred in early 1985, when the dollar was universally reckoned to be dangerously dear. At that time the US was able to call on trading partners who depended on the US security umbrella – the UK, Germany, France and Japan – to negotiate the ‘Plaza Accord’, which coordinated a series of interventions in the foreign exchange market that allowed the dollar to decline in a measured way. Without much scope for a negotiated decline in the dollar, more chaotic alternatives seem likely. It is virtually unimaginable that something similar could be negotiated today, not least because Chinese policymakers believe that the post-Plaza strengthening of the yen in the late 1980s led to an economic disaster for Japan. Beijing will not play ball.Without much scope for a negotiated decline in the dollar, more chaotic alternatives seem likely. One is that the market decides suddenly that it no longer has an appetite for expensive dollar-denominated assets, and this might lead to a messy adjustment in the foreign exchange market. Full Article
li Implications of the new US presidency: what awaits Ukraine? By www.chathamhouse.org Published On :: Wed, 13 Nov 2024 11:27:13 +0000 Implications of the new US presidency: what awaits Ukraine? 19 November 2024 — 2:00PM TO 3:30PM Anonymous (not verified) 13 November 2024 Online After 1000 days of Kyiv’s resistance, experts discuss how to secure Ukraine’s and Europe’s future. The 19 November marks 1,000 days since Russia’s full-scale invasion of Ukraine. The country faces an ever-more ferocious fight for its future existence. The 19th November marks 1,000 days since Russia’s full-scale invasion of Ukraine. The country faces an ever-more ferocious fight for its future existence.Having been given time to adapt, largely due to the slow release of Western military aid, the Russian army is pressing home its advantage. Along the entire eastern frontline, the Russians are simultaneously bombarding Ukraine’s energy infrastructure and cities. With the election of Donald Trump in the US, it seems to many that the tide has turned definitively in Putin’s favour at the political, as well as the military, level.Trump’s declared ambition to resolve the war in 24 hours implies a Russian-American deal, cutting Kyiv out of negotiations. Such an ‘agreement’ would endanger the country’s future and expose the rest of Europe.This webinar will cover:Ukraine’s strategy of resistance in the context of Trump’s White House.The immediate risks during the transition period.How Kyiv sees Europe’s role in the new geopolitical environment. Will Kyiv completely give up on the US?The extent to which Germany, Ukraine’s second largest donor, can step in. Full Article
li Familiar faces open Rockies spring camp By mlb.mlb.com Published On :: Tue, 12 Feb 2019 14:40:58 EDT Familiar sounds of encouragement and needling filled a practice field at Salt River Fields at Talking Stick on Monday as Nolan Arenado, Trevor Story and the infielders took grounders and Charlie Blackmon and the outfielders gathered their bats and spikes. Only a few faces that always seemed to be around are missing as Spring Training begins. Full Article
li Arenado won't set hard deadline on negotiations By mlb.mlb.com Published On :: Thu, 14 Feb 2019 15:20:25 EDT Rockies third baseman Nolan Arenado said Thursday he won't make Opening Day a hard deadline for negotiations on a possible multiyear contract. Full Article
li Black likes Blackmon in role of leading man By mlb.mlb.com Published On :: Fri, 15 Feb 2019 15:55:44 EDT A year after looking for ways to move Charlie Blackmon out of the leadoff spot, Rockies manager Bud Black is counting the reasons to keep him up top. Full Article
li Rockies' Top 30 Prospects list By m.mlb.com Published On :: Mon, 26 Feb 2018 11:18:00 EDT Who do the Rockies have in the pipeline? Get scouting reports, video, stats, projected ETAs and more for Colorado's Top 30 Prospects on MLBPipeline.com's Prospect Watch. Full Article
li Out of options, Tapia must deliver in 2019 By mlb.mlb.com Published On :: Sun, 17 Feb 2019 19:16:05 EDT Raimel Tapia has renewed opportunity with the Rockies in 2019, along with a need to deliver. Full Article
li US drug makers have imposed big price rises for top selling drugs, study finds By www.bmj.com Published On :: Tuesday, April 5, 2016 - 14:01 Full Article
li Australian neuroscientist given two year suspended sentence for falsifying Parkinson's research By www.bmj.com Published On :: Thursday, April 7, 2016 - 12:41 Full Article
li Health anxiety: the silent, disabling epidemic By www.bmj.com Published On :: Monday, April 25, 2016 - 10:01 Full Article
li Blue Jays' hope for 2019 lies in the future By mlb.mlb.com Published On :: Fri, 8 Feb 2019 17:09:20 EDT The Blue Jays spent the past two years clinging to the past. Now, they're embracing the future. Full Article
li Blue Jays' Top 30 Prospects list By m.mlb.com Published On :: Fri, 17 Feb 2017 21:05:43 EDT Who do the Blue Jays have in the pipeline? Get scouting reports, video, stats, projected ETAs and more for Toronto's Top 30 Prospects on MLB Pipeline's Prospect Watch. Full Article
li Correspondence on 'Dispute arises over World Professional Association for Transgender Health’s involvement in WHO’s trans health guideline' by Jennifer Block By www.bmj.com Published On :: Wednesday, November 13, 2024 - 09:02 Full Article
li Re: Patient involvement in developing clinical guidelines By www.bmj.com Published On :: Wednesday, November 13, 2024 - 11:38 Full Article
li Malcolm Donaldson: paediatric endocrinologist, musician, and proud collaborator with his wife Julia, author of The Gruffalo By www.bmj.com Published On :: 2024-11-12T05:11:43-08:00 bmj;387/nov12_10/q2481/FAF1faJulia and Malcolm Donaldsondonaldson20241111.f1Malcolm Donaldson was a distinguished paediatric endocrinologist with a string of research publications to his name—but he was also happy to play second fiddle (almost literally) to his wife Julia, the celebrated author of much loved children’s books, including The Gruffalo and Room on the Broom.Malcolm, a talented musician and performer, accompanied his wife as she toured festivals, schools, and libraries in the UK and around the world. Together they performed the stories, with Malcolm acting characters ranging from an accident prone dragon to a comic cattle thief. His star role, in the words of Julia’s literary agent, was “a particularly suave fox” in The Gruffalo.Malcolm met Julia Shields when they were students at the University of Bristol and they married in 1972. Donaldson went on to work in Brighton, London, and Lyon, France, before moving back to Bristol to be a senior registrar in paediatrics. Six... Full Article
li Cardiovascular disease: Just one in 12 eligible people had health check last year, watchdog finds By www.bmj.com Published On :: 2024-11-13T08:26:17-08:00 The current system for delivering NHS cardiovascular disease (CVD) health checks is not working effectively and must be reviewed to ensure that it reaches people with the highest risk, the National Audit Office has said.1In a review of the commissioning, delivery, and performance of CVD health checks the watchdog found that just over one in 12 people (8.8%) who were eligible attended a health check in 2023-24—which, if maintained, would equate to a five year coverage of 44%.Health checks were first introduced in 2009, with the aim of reducing ill health from CVD by offering everyone aged 40-74 without a pre-existing heart condition a check-up every five years. However, problems have arisen since the responsibility for commissioning these checks was transferred to local authorities in 2013, said the National Audit Office.The move led to the Department of Health and Social Care (DHSC) losing its ability to influence local authority performance,... Full Article
li Encoding of Vibrotactile Stimuli by Mechanoreceptors in Rodent Glabrous Skin By www.jneurosci.org Published On :: 2024-11-13T09:30:19-08:00 Somatosensory coding in rodents has been mostly studied in the whisker system and hairy skin, whereas the function of low-threshold mechanoreceptors (LTMRs) in the rodent glabrous skin has received scant attention, unlike in primates where the glabrous skin has been the focus. The relative activation of different LTMR subtypes carries information about vibrotactile stimuli, as does the rate and temporal patterning of LTMR spikes. Rate coding depends on the probability of a spike occurring on each stimulus cycle (reliability), whereas temporal coding depends on the timing of spikes relative to the stimulus cycle (precision). Using in vivo extracellular recordings in male rats and mice of either sex, we measured the reliability and precision of LTMR responses to tactile stimuli including sustained pressure and vibration. Similar to other species, rodent LTMRs were separated into rapid-adapting (RA) or slow-adapting based on their response to sustained pressure. However, unlike the dichotomous frequency preference characteristic of RA1 and RA2/Pacinian afferents in other species, rodent RAs fell along a continuum. Fitting generalized linear models to experimental data reproduced the reliability and precision of rodent RAs. The resulting model parameters highlight key mechanistic differences across the RA spectrum; specifically, the integration window of different RAs transitions from wide to narrow as tuning preferences across the population move from low to high frequencies. Our results show that rodent RAs can support both rate and temporal coding, but their heterogeneity suggests that coactivation patterns play a greater role in population coding than for dichotomously tuned primate RAs. Full Article
li Monocyte Invasion into the Retina Restricts the Regeneration of Neurons from Müller Glia By www.jneurosci.org Published On :: 2024-11-13T09:30:19-08:00 Endogenous reprogramming of glia into neurogenic progenitors holds great promise for neuron restoration therapies. Using lessons from regenerative species, we have developed strategies to stimulate mammalian Müller glia to regenerate neurons in vivo in the adult retina. We have demonstrated that the transcription factor Ascl1 can stimulate Müller glia neurogenesis. However, Ascl1 is only able to reprogram a subset of Müller glia into neurons. We have reported that neuroinflammation from microglia inhibits neurogenesis from Müller glia. Here we found that the peripheral immune response is a barrier to CNS regeneration. We show that monocytes from the peripheral immune system infiltrate the injured retina and negatively influence neurogenesis from Müller glia. Using CCR2 knock-out mice of both sexes, we found that preventing monocyte infiltration improves the neurogenic and proliferative capacity of Müller glia stimulated by Ascl1. Using scRNA-seq analysis, we identified a signaling axis wherein Osteopontin, a cytokine highly expressed by infiltrating immune cells is sufficient to suppress mammalian neurogenesis. This work implicates the response of the peripheral immune system as a barrier to regenerative strategies of the retina. Full Article
li Cycling to the unreached By www.om.org Published On :: Thu, 28 Jun 2012 13:14:34 +0000 Staff from OM SportsLink and Campus Crusade for Christ cycled from Pretoria to Cape Town to minister to people in rural villages along the way. Full Article
li Vegetables that save lives By www.om.org Published On :: Mon, 27 Aug 2012 03:27:11 +0000 If you only owned the ground you stood on, how would you make the most out of it? A creative idea becomes a sustainable reality. Full Article
li The Link in South Africa By www.om.org Published On :: Wed, 31 Oct 2012 14:15:18 +0000 Five OM entities based in South Africa previously working in three separate offices throughout Pretoria have recently united under one roof. Full Article
li Coaching for life in Randfontein By www.om.org Published On :: Fri, 20 Sep 2013 13:47:40 +0000 Community leaders in South Africa met with SportsLink to discuss how coaches can impact the fatherless in Randfontein. Full Article
li Mieliemeel miracle By www.om.org Published On :: Mon, 06 Jan 2014 15:05:02 +0000 God unexpectedly provides just what a family needs. Full Article
li Discipling boys through sport By www.om.org Published On :: Fri, 10 Oct 2014 08:38:10 +0000 OM SportsLink ministers to young boys in Mamelodi, the largest township of Pretoria, South Africa, every Friday. Full Article
li Voicing the plight of the vulnerable By www.om.org Published On :: Tue, 04 Apr 2017 06:36:34 +0000 In October, 140 people take the Table Mountain Challenge in Cape Town and Franschhoek, South Africa, as part of the Freedom Climb. Full Article
li Light in the darkness By www.om.org Published On :: Mon, 09 Mar 2015 16:36:32 +0000 OM AIDS Hope, in collaboration with Stanza Bopape Clinic, arranges an event on World AIDS Day 2014 to bring light to the pandemic. Full Article
li Standing up for the marginalised By www.om.org Published On :: Wed, 08 Apr 2015 17:51:26 +0000 Jabulani, a youth from South Africa affected by HIV, receives help and care from the OM team ministering in his community. Full Article
li New chapter of life By www.om.org Published On :: Fri, 26 Aug 2016 15:26:02 +0000 During the Go Challenge, the team is asked to pray for an elderly woman while doing door to door ministry in Tzaneen. Full Article
li There's more to life than rugby By www.om.org Published On :: Tue, 07 Mar 2017 09:39:55 +0000 For the past two years OM South Africa SportsLink has attended a prestigious rugby tournament to spread the good news to players, coaches and staff. Full Article
li Dabbling in the office of dreams By www.om.org Published On :: Wed, 28 Jun 2017 00:13:23 +0000 For the OM Africa communications and media team, the latest and greatest thing is a duck. Full Article
li Your life turned upside down in 10 minutes By www.om.org Published On :: Fri, 22 Mar 2013 14:09:05 +0000 OM Russia works to bring hope to neighbours affected by HIV and AIDS. Full Article
li What’s killing Russia’s youth? By www.om.org Published On :: Mon, 14 Oct 2013 15:50:42 +0000 OM Russia and partner organisations work to thwart two killers picking off the younger generation in Russia: drugs and HIV and AIDS. Full Article
li Internet evangelism, Internet dating and the Internet in world mission By www.om.org Published On :: Mon, 21 Oct 2013 05:59:02 +0000 A young couple who met on the Internet answers God’s call to missions to help others find Christ using their IT and web design skills. Full Article
li Rebuilding lives in a new city By www.om.org Published On :: Thu, 25 Sep 2014 08:53:24 +0000 OM Russia partners with local churches to respond to the needs of Ukrainian refugees in Novosibirsk, Siberia. Full Article
li OM Russia: A mission team for families By www.om.org Published On :: Fri, 10 Oct 2014 07:38:02 +0000 OM Russia leader Colin Cleaver discusses why he values the involvement of families in OM Russia’s ministry and encourages other families to consider missions. Full Article
li Rehabilitation through love and action By www.om.org Published On :: Mon, 14 Nov 2016 19:31:22 +0000 The church in Russia is facing a new threat-HIV/AIDS. OM Russia works in rehab-centres to show God's love and compassion. Full Article
li “I am not worth it to believe in Jesus." By www.om.org Published On :: Mon, 14 Nov 2016 19:42:57 +0000 A Dutch team member shares her mission trip experience praying with a man in Siberia. Full Article
li Seeing hearts, not the disabilities By www.om.org Published On :: Mon, 14 Nov 2016 20:13:13 +0000 OM Russia had a great kick-off to the STM summer season by serving in a camp for children with disabilities to hear about Christ. Full Article