Would happy lab animals—rats, mice, even zebrafish—make for better experiments? David Grimm—online news editor for Science—talks with Sarah Crespi about the potential of treating lab animals more like us and making them more useful for science at the same time. Sarah also interviews Jon Abbatt of the University of Toronto in Canada about indoor chemistry. What is going on in the air inside buildings—how different is it from the outside? Researchers are bringing together the tools of outdoor chemistry and building sciences to understand what is happening in the air and on surfaces inside—where some of us spend 90% of our time. Listen to previous podcasts. [Image: Austin Thomason/Michigan Photography; Music: Jeffrey Cook]

Some of our genes come alive after we die. David Grimm—online news editor for Science—talks with Sarah Crespi about which genes are active after death and what we can learn about time of death by looking at patterns of postmortem gene expression. Sarah also interviews David Merritt Johns of Columbia University about the so-called sugar conspiracy. Historical evidence suggests, despite recent media reports, it is unlikely that “big sugar” influenced U.S. nutrition policy and led to the low-fat diet fad of the ’80s and ’90s. Listen to previous podcasts. [Image: Lauri Andler (Phantom); Music: Jeffrey Cook]

For some time after the big bang there were no stars. Researchers are now looking at cosmic dawn—the time when stars first popped into being—and are seeing hints of dark matter’s influence on supercold hydrogen clouds. News Writer Adrian Cho talks with Sarah Crespi about how this observation was made and what it means for our understanding of dark matter. Sarah also interviews Joanna Kaplanis of the Wellcome Sanger Institute in Hinxton, U.K., about constructing enormous family trees based on an online social genealogy platform. What can we learn from the biggest family tree ever built—with 13 million members spanning 11 generations? In a bonus segment recording during a live podcasting event at the AAAS Annual Meeting in Austin, Sarah talks with Michael Varnum of Arizona State University in Tempe about what people think they will do if humanity comes into contact with aliens that just happen to be microbes. Live recordings sessions at the AAAS meeting were supported by funds from the European Commission. This week’s episode was edited by Podigy. Listen to previous podcasts. [Image: Kilo-Degree Survey Collaboration/H. Hildebrandt & B. Giblin/ESO; Music: Jeffrey Cook]  

Did people domesticate animals? Or did they domesticate themselves? Online News Editor David Grimm talks with Sarah Crespi about a recent study that looked at self-domesticating mice. If they could go it alone, could cats or dogs have done the same in the distant past? Next, Sinan Aral of the Massachusetts Institute of Technology in Cambridge joins Sarah to discuss his work on true and false rumor cascades across all of Twitter, since its inception. He finds that false news travels further, deeper, and faster than true news, regardless of the source of the tweet, the kind of news it was, or whether bots were involved. In a bonus segment recording during a live podcasting event at the AAAS Annual Meeting in Austin, Sarah first speaks with Ben Munson of the University of Minnesota in Minneapolis about markers of gender and sexual orientation in spoken language and then Adrienne Hancock of The George Washington University in Washington, D.C., talks about using what we know about gender and communication to help transgender women change their speech and communication style. Live recordings sessions at the AAAS meeting were supported by funds from the European Commission. This week’s episode was edited by Podigy. Listen to previous podcasts. [Image: Rudolf Jakkel (CC0); Music: Jeffrey Cook]

When Indonesia’s Mount Toba blew its top some 74,000 years ago, an apocalyptic scenario ensued: Tons of ash and debris entered the atmosphere, coating the planet in ash for 2 weeks straight and sending global temperatures plummeting. Despite the worldwide destruction, humans survived. Sarah Crespi talks with Online News Editor Catherine Matacic about how life after Toba was even possible—were humans decimated, or did they rally in the face of a suddenly extra hostile planet? Next, Julia Buck of the University of California, Santa Barbara, joins Sarah to discuss her Science commentary piece on landscapes of disgust. You may have heard of a landscape of fear—how a predator can influence an ecosystem not just by eating its prey, but also by introducing fear into the system, changing the behavior of many organisms. Buck and colleagues write about how disgust can operate in a similar way: Animals protect themselves from parasites and infection by avoiding disgusting things such as dead animals of the same species or those with disease. This week’s episode was edited by Podigy. Listen to previous podcasts. [Image: Emma Forsber/Flickr; Music: Jeffrey Cook]

Researchers are converging on which genes are linked to morning sickness—the nausea and vomiting associated with pregnancy—and the more severe form: hyperemesis gravidarum (HG). And once we know what those genes are—can we help pregnant women feel better? News intern Roni Dengler joins Sarah Crespi to talk about a new study that suggests a protein already flagged for its role in cancer-related nausea may also be behind HG. In a second segment, Tracy Bedrosian of the Neurotechnology Innovations Translator talks about how the amount of time spent being licked by mom might be linked to changes in the genetic code of hippocampal neurons in mice pups. Could these types of genomic changes be a new type of plasticity in the brain? This week’s episode was edited by Podigy. Listen to previous podcasts. [Image: Jacob Bøtter/Flickr; Music: Jeffrey Cook]

Two of the world’s most famous research chimpanzees have finally retired. Hercules and Leo arrived at a chimp sanctuary in Georgia last week. Sarah Crespi checks in with Online News Editor David Grimm on the increasing momentum for research chimp retirement since the primates were labeled endangered species in 2015. Sarah also interviews freelancer Sophia Chen about her piece on x-ray ghost imaging—a technique that may lead to safer medical imaging done with cheap, single-pixel cameras. David Malakoff joins Sarah to talk about the big boost in U.S. science funding signed into law over the weekend. Finally, Jen Golbeck interviews author Stephanie Elizabeth Mohr on her book First in Fly: Drosophila Research and Biological Discovery for our monthly books segment. This week’s episode was edited by Podigy. Listen to previous podcasts. [Image: Crystal Alba/Project Chimps; Music: Jeffrey Cook]

Geneticists and anthropologists studying historical records and modern-day genomes are finding traces of previously unknown migrants to Latin America in the 16th and 17th centuries, when Asians, Africans, and Europeans first met indigenous Latin Americans. Sarah Crespi talks with contributing correspondent Lizzie Wade about what she learned on the topic at the American Association of Physical Anthropologists’s annual meeting in Austin. Sarah also interviews Kang-Keun Ni about her research using optical tweezers to bring two atoms—one cesium and one sodium—together into a single molecule. Such precise control of molecule formation is allowing new observations of these basic processes and is opening the door to creating new molecules for quantum computing. This week’s episode was edited by Podigy. Listen to previous podcasts. [Image: Juan Fernando Ibarra; Music: Jeffrey Cook] 

To study the biological differences brought on by space travel, NASA sent one twin into space and kept another on Earth in 2015. Now, researchers from that project are trying to replicate that work planet-side to see whether the differences in gene expression were due to extreme stress or were specific to being in space. Sarah Crespi talks with Online News Editor Catherine Matacic about a “control” study using what might be a comparably stressful experience here on Earth: climbing Mount Everest. Catherine also shares a recent study that confirmed what one reddit user posted 5 years ago: A single path stretching from southern Pakistan to northeastern Russia will take you on the longest straight-line journey on Earth, via the ocean. Finally, Sarah talks with Roland Kröger of the University of York in the United Kingdom about his group’s study published this week in Science. Using a combination of techniques usually reserved for materials science, the group explored the nanoscale arrangement of mineral in bone, looking for an explanation of the tissue’s contradictory combination of toughness and hardness. This week’s episode was edited by Podigy. Listen to previous podcasts. [Image: Human bone (20X) by Berkshire Community College Bioscience Image Library; Music: Jeffrey Cook]

Two thousand years ago, ancient Romans were pumping lead into the air as they smelted ores to make the silvery coin of the realm. Online News Editor David Grimm talks to Sarah Crespi about how the pollution of ice in Greenland from this process provides a detailed 1900-year record of Roman history. This week is also resistance week at Science—where researchers explore the global challenges of antibiotic resistance, pesticide resistance, herbicide resistance, and fungicide resistance. Sarah talks with Sarah Gurr of the University of Exeter in the United Kingdom about her group’s work on the spread of antifungal resistance and what it means for crops and in the clinic. And in a bonus books segment, staff writer Jennifer Couzin-Frankel talks about medicine and fraud in her review of Bad Blood: Secrets and Lies in a Silicon Valley Startup by John Carreyrou. This week’s episode was edited by Podigy. Listen to previous podcasts. [Image: Wheat rust/Oregon State University; Music: Jeffrey Cook]

DNA fingerprinting has been used to link people to crimes for decades, by matching DNA from a crime scene to DNA extracted from a suspect. Now, investigators are using other parts of the genome—such as markers for hair and eye color—to help rule people in and out as suspects. Staff Writer Gretchen Vogel talks with Sarah Crespi about whether science supports this approach and how different countries are dealing with this new type of evidence. Sarah also talks with Jill Fernandes of the University of Queensland in Brisbane, Australia, about her Science Advances paper on a light-based technique for detecting Zika in mosquitoes. Instead of grinding up the bug and extracting Zika DNA, her group shines near-infrared light through the body. Mosquitoes carrying Zika transmit this light differently from uninfected ones. If it’s successful in larger trials, this technique could make large-scale surveillance of infected mosquitoes quicker and less expensive. In our monthly books segment, Jen Golbeck talks with author Sarah-Jayne Blakemore about her new work: Inventing Ourselves: The Secret Life of the Teenage Brain. You can check out more book reviews and share your thoughts on the Books et al. blog. This week’s episode was edited by Podigy. Listen to previous podcasts. [Image: National Institute of Allergy and Infectious Diseases, National Institutes of Health; Music: Jeffrey Cook]

Astronomers have been able to detect supermassive black holes and teeny-weeny black holes but the midsize ones have been elusive. Now, researchers have scanned through archives looking for middle-size galaxies and found traces of these missing middlers. Host Sarah Crespi and Staff Writer Daniel Clery discuss why they were so hard to find in the first place, and what it means for our understanding of black hole formation. Farming animals and plants for human consumption is a massive operation with a big effect on the planet. A new research project that calculated the environmental impact of global food production shows highly variable results for different foods—and for the same foods grown in different locations. Sarah talks with one of the researchers—Joseph Poore of the University of Oxford in the United Kingdom—about how understanding this diversity can help cut down food production’s environmental footprint and help consumers make better choices. This week’s episode was edited by Podigy. Listen to previous podcasts. [Image: Miltos Gikas/Flickr; Music: Jeffrey Cook]

What book are you taking to the beach or the field this summer? Science’s books editor Valerie Thompson and host Sarah Crespi discuss a selection of science books that will have you catching comets and swimming with the fishes. Sarah also talks with Mira Moufarrej of Stanford University in Palo Alto, California, about her team’s work on a new blood test that analyzes RNA from maternal blood to determine the gestational age of a fetus. This new approach may also help predict the risk of preterm birth. This week’s episode was edited by Podigy. Listen to previous podcasts. [Image: William Warby/Flickr; Music: Jeffrey Cook]

Nigeria, Russia, and Florida seem like an odd set, but they all have one thing in common: growing caseloads of HIV. Science Staff Writer Jon Cohen joins host Sarah Crespi to talk about this week’s big read on how the fight against HIV/AIDS is evolving in these diverse locations. Sarah also talks with Armin Raznahan of the National Institute of Mental Health in Bethesda, Maryland, about his group’s work measuring which parts of the human brain are bigger in bigger brains. Adult human brains can vary as much as two times in size—and until now this expansion was thought to be evenly distributed. However, the team found that highly integrative regions are overrepresented in bigger brains, whereas regions related to processing incoming sensory information such as sight and sound tend to be underrepresented.  This week’s episode was edited by Podigy. Listen to previous podcasts. [Image: Misha Friedman; Music: Jeffrey Cook]

Since the 2016 reports of a mysterious assault on U.S. embassy staff in Cuba, researchers have struggled to find evidence of injury or weapon. Now, new research has discovered inner-ear damage in some of the personnel complaining of symptoms. Former International News Editor Rich Stone talks to host Sarah Crespi about the case, including new reports of a similar incident in China, and what kind of weapon—if any—might have been involved. Sarah also talks with Staff Writer Gretchen Vogel about the bones of an extinct gibbon found in a 2200- to 2300-year-old tomb in China. Although gibbons were often featured in historical poetry and paintings, these bones confirm their presence and the fact that they were distinct from today’s species.   Read the research. This week’s episode was edited by Podigy. Listen to previous podcasts. [Image: Pedro Szekely; Music: Jeffrey Cook] 

Public opinion on the morality of animal research is on the downswing in the United States. But some researchers think letting the public know more about how animals are used in experiments might turn things around. Online News Editor David Grimm joins Sarah Crespi to talk about these efforts. Sarah also talks Ken Wachter of the University of California, Berkeley about his group’s careful analysis of data from all living Italians born 105 or more years before the study. It turns out the risk of dying does not continue to accelerate with age, but actually plateaus around the age of 105. What does this mean for attempts to increase human lifespan? In this month’s book segment, Jen Golbeck talks with Simon Winchester about his book The Perfectionists: How Precision Engineers Created the Modern World. Read more book reviews at our books blog, Books et al. This week’s episode was edited by Podigy. Listen to previous podcasts. [Image: Chris Jones/Flickr; Music: Jeffrey Cook]

A detection of a single neutrino at the 1-square-kilometer IceCube detector in Antarctica may signal the beginning of “neutrino astronomy.” The neutral, almost massless particle left its trail of debris in the ice last September, and its source was picked out of the sky by the Fermi Gamma-ray Space Telescope soon thereafter. Science News Writer Daniel Clery joins host Sarah Crespi to discuss the blazar fingered as the source and how neutrinos from this gigantic matter-gobbling black hole could help astronomers learn more about mysterious high-energy cosmic rays that occasionally shriek toward Earth. Read the research. Sarah also talks with Cornell University’s Susan McCouch about her team’s work on deep-water rice. Rice can survive flooding by fast internodal growth—basically a quick growth spurt that raises its leaves above water. But this growth only occurs in prolonged, deep flooding. How do these plants know they are submerged and how much to grow? Sarah and Susan discuss the mechanisms involved and where they originated. This week’s episode was edited by Podigy. Download a transcript of this episode (PDF) Listen to previous podcasts. [Image: NASA/Goddard Space Flight Center Conceptual Image Lab; Music: Jeffrey Cook]

Suckling mothers milk is a pretty basic feature of being a mammal. Humans do it. Possums do it. But monotremes such as the platypus and echidna—although still mammals—gave up suckling long ago. Instead, they lap at milky patches on their mothers’ skin to get early sustenance. Science News Writer Gretchen Vogel talks with host Sarah Crespi about the newest suckling science—it turns out monotremes probably had suckling ancestors, but gave it up for the ability to grind up tasty, hard-shelled, river-dwelling creatures. Sarah also talks with Sandra Yuter of North Carolina State University in Raleigh about her work on fast-clearing clouds off the southwest coast of Africa. These immense marine layers appear to be exiting the coastal regions under the influence of gravity waves (not to be confused with gravitational waves). This finding can help scientists better model cloud behavior, particularly with respect to their influence on global temperatures. This week’s episode was edited by Podigy. Download a transcript of this episode (PDF) Listen to previous podcasts. [Image: North Carolina State University]    

Yes, humans are the only species with language, but how did we acquire it? New research suggests our linguistic prowess might arise from the same process that brought domesticated dogs big eyes and bonobos the power to read others’ intent. Online News Editor Catherine Matacic joins host Sarah Crespi to talk about how humans might have self-domesticated themselves, leading to physical and behavioral changes that gave us a “language-ready” brain. Sarah also talks with Micah Edelson of the University of Zurich in Switzerland about his group’s research into the role that “responsibility aversion”—the reluctance to make decisions for a group—might play when people decide to lead or defer in a group setting. In their experiments, the team found that some people adjusted how much risk they would take on, depending on whether they were deciding for themselves alone or for the entire group. The ones who didn’t—those who stuck to the same plan whether others were involved or not—tended to score higher on standardized tests of leadership and have held higher military rank. This week’s episode was edited by Podigy. Download a transcript of this episode (PDF) Listen to previous podcasts. [Image: Scaly breasted munia/Ravi Vaidyanathan; Music: Jeffrey Cook]

We now live in the Meghalayan age—the last age of the Holocene epoch. Did you get the memo? A July decision by the International Commission on Stratigraphy, which is responsible for naming geological time periods, divided the Holocene into three ages: the Greenlandian, the Northgrippian, and the Meghalayan. The one we live in—the Meghalayan age (pronounced “megalion”)—is pegged to a global drought thought to have happened some 4200 years ago. But many critics question the timing of this latest age and the global expanse of the drought. Staff writer Paul Voosen talks with host Sarah Crespi about the evidence for and against the global drought—and what it means if it’s wrong. Sarah also talks to staff writer Kelly Servick about her feature story on what happens when biocontrol goes out of control. Here’s the setup: U.S. Department of Agriculture researchers wanted to know whether brown marmorated stink bugs that have invaded the United States could be controlled—aka killed—by importing their natural predators, samurai wasps, from Asia. But before they could find out, the wasps showed up anyway. Kelly discusses how using one species to combat another can go wrong—or right—and what happens when the situation outruns regulators. This week’s episode was edited by Podigy. Download a transcript of this episode (PDF) Listen to previous podcasts. [Image: Melissa McMasters/Flickr; Music: Jeffrey Cook] 

Several thousand years ago the volcano under Santorini in Greece—known as Thera—erupted in a tremendous explosion, dusting the nearby Mediterranean civilizations of Crete and Egypt in a layer of white ash. This geological marker could be used to tie together many ancient historical events, but the estimated date could be off by a century. Contributing Correspondent Lizzie Wade joins host Sarah Crespi to talk about a new study that used tree rings to calibrate radiocarbon readings—and get closer to pinning down a date. The findings also suggest that scientists may need to change their standard radiocarbon dating calibration curve. Sarah also talks to Tony Belpaeme of Ghent University in Belgium and Plymouth University in the United Kingdom about his Science Robotics paper that explored whether people are susceptible to peer pressure from robots. Using a classic psychological measure of peer influence, the team found that kids from ages 7 to 9 occasionally gave in to social pressure from robot peers, but adults did not. This week’s episode was edited by Podigy, with help from Meagan Cantwell. Download a transcript of this episode (PDF) Listen to previous podcasts. About the Science Podcast [Image: Softbank Robotics; Music: Jeffrey Cook]

Small satellites—about the size of a briefcase—have been hitching rides on rockets to lower Earth orbit for decades. Now, because of their low cost and ease of launching, governments and private companies are looking to expand the range of these “sate-lites” deeper into space. Host Sarah Crespi talks with Deputy News Editor Eric Hand about the mods and missions in store for so-called CubeSats. And our newest podcast producer Meagan Cantwell interviews Quentin Grafton of Australian National University in Canberra and Brad Udall of Colorado State University in Fort Collins about something called the “irrigation efficiency paradox.” As freshwater supplies dry up around the world, policymakers and farmers have been quick to try to make up the difference by improving irrigation, a notorious water waster. It turns out that both human behavior and the difficulty of water measurement are plaguing water conservation efforts in agriculture. For example, when farms find they are using less water, they tend to plant ever-more-water-intensive crops. Now, researchers are trying to get the message out about the behavioral component of this issue and tackle the measurement problem, using cheap remote-sensing technology, but with water scarcity looming ahead, we have to act soon. This week’s episode was edited by Podigy. Download a transcript of this episode (PDF) Listen to previous podcasts. About the Science Podcast [Image: John A. Kelley, USDA Natural Resources Conservation Service; Music: Jeffrey Cook]

A new project out of the Center for Open Science in Charlottesville, Virginia, found that of all the experimental social science papers published in Science and Nature from 2010–15, 62% successfully replicated, even when larger sample sizes were used. What does this say about peer review? Host Sarah Crespi talks with Staff Writer Kelly Servick about how this project stacks up against similar replication efforts, and whether we can achieve similar results by merely asking people to guess whether a study can be replicated. Podcast producer Meagan Cantwell interviews Emily Brodsky of the University of California, Santa Cruz, about her research report examining why earthquakes occur as far as 10 kilometers from wastewater injection and fracking sites. Emily discusses why the well-established mechanism for human-induced earthquakes doesn’t explain this distance, and how these findings may influence where we place injection wells in the future. In this month’s book podcast, Jen Golbeck interviews Judea Pearl and Dana McKenzie, authors of The Book of Why: The New Science of Cause and Effect. They propose that researchers have for too long shied away from claiming causality and provide a road map for bringing cause and effect back into science. This week’s episode was edited by Podigy. Download a transcript of this episode (PDF) Listen to previous podcasts. About the Science Podcast [Image: Jens Lambert, Shutterstock; Music: Jeffrey Cook]

We are in the middle of what some scientists are calling the sixth mass extinction and not all at-risk species can be saved. That’s causing some conservationists to say we need to start thinking about “species triage.” Meagan Cantwell interviews freelance journalist Warren Cornwall about his story on weighing the costs of saving Canada’s endangered caribou and the debate among conservationists on new approaches to conservation. And host Sarah Crespi interviews Hope Michelsen, a staff scientist at Sandia National Laboratories in Livermore, California, about mysterious origins of soot. The black dust has been around since fire itself, but researchers never knew how the high-energy environment of a flame can produce it—until now. Michelsen walks Sarah through the radical chemistry of soot formation—including its formation of free radicals—and discusses soot’s many roles in industry, the environment, and even interstellar space. Check out this useful graphic describing the soot inception process in the related commentary article. This week’s episode was edited by Podigy. Download a transcript of this episode (PDF) Listen to previous podcasts. About the Science Podcast [Image: Darren Bertram/Flickr; Music: Jeffrey Cook]

Strawberries had both male and female parts, like most plants, until several million years ago. This may seem like a long time ago, but it actually means strawberries have some of the youngest sex chromosomes around. What are the advantages of splitting a species into two sexes? Host Sarah Crespi interviews freelance journalist Carol Cruzan Morton about her story on scientists’ journey to understanding the strawberry’s sexual awakening. In 2016, experimental Zika vaccines were swiftly developed in response to the emergence of serious birth defects in the babies of infected woman. Two years after the height of Zika cases, there’s so little spread of the virus in the Americas that it has stymied vaccine trials. Researchers hope to overcome this hurdle with “human challenge experiments”—vaccinating people, then intentionally infecting them with Zika to see whether they’re protected from the virus. Meagan Cantwell talks with staff writer Jon Cohen about his news story that highlights the risks and rewards of human challenge experiments. This week’s episode was edited by Podigy. Download a transcript of this episode (PDF) Listen to previous podcasts. About the Science Podcast [Image: Public domain; Music: Jeffrey Cook]

Meta-analyses—structured analyses of many studies on the same topic—were once seen as objective and definitive projects that helped sort out conflicts amongst smaller studies. These days, thousands of meta-analyses are published every year—many either redundant or contrary to earlier metaworks. Host Sarah Crespi talks to freelance science journalist Jop de Vrieze about ongoing meta-analysis wars in which opposing research teams churn out conflicting metastudies around important public health questions such as links between violent video games and school shootings and the effects of antidepressants. They also talk about what clues to look for when trying to evaluate the quality of a meta-analysis. Sarah also talked with three other contributors to our “Research on Research” special issue. Pierre Azoulay of the Massachusetts Institute of Technology (MIT) in Cambridge, Ben Jones of Northwestern University in Evanston, Illinois, and MIT’s Heidi Williams discuss the evidence for some hoary old scientific home truths. See whether you can guess who originally made these claims and how right or wrong they were: Do scientists make great contributions after age 30? How important is it to stand on the shoulders of giants? Does the truth win, or do its opponents just eventually die out? Read the rest of the package on science under scrutiny here. This week’s episode was edited by Podigy. Download a transcript of this episode (PDF) Listen to previous podcasts. About the Science Podcast [Image: Davide Bonazzi/@SalzmanArt; Show music: Jeffrey Cook; additional music: Nguyen Khoi Nguyen]

Science has often treated Indigenous people as resources for research—especially when it comes to genomics. Now, Indigenous people are exploring how this type of study can be conducted in a way that respects their people and traditions. Meagan Cantwell talks with contributing correspondent Lizzie Wade about a summer workshop for Indigenous scientists that aims to start a new chapter in genomics. We’ve known for decades that PCBs—polychlorinated biphenyls—are toxic and carcinogenic. In the 1970s and 1980s, these compounds were phased out of use in industrial and electronic applications, worldwide. But they are still in the environment—in soil and air—and in animal tissues, particularly those of killer whales. These toxic compounds start out at minute levels in tiny organisms, but as the small are eaten by the slightly larger, the PCB concentration increases—from plankton, to fish, to seals—until you are at killer whales with PCB-packed blubber. Ailsa Hall, director of the Sea Mammal Research Unit at St. Andrews University in the United Kingdom, talks with host Sarah Crespi about her group’s work measuring PCB levels in different killer whale populations and calculating the effect of PCBs on those populations 100 years from now. In this month’s book segment, Jen Golbeck interviews Damon Centola about his book How Behavior Spreads: The Science of Complex Contagions. You can listen to more books segment and read more reviews on our books blog, Books et al.  This week’s episode was edited by Podigy. Download a transcript of this episode (PDF) Listen to previous podcasts About the Science Podcast [Image: Public domain; Music: Jeffrey Cook] 

Hoping to spot subatomic particles called neutrinos smashing into Earth, the balloon-borne Antarctic Impulsive Transient Antenna (ANITA) detector has circled the South Pole four times. ANITA has yet to detect those particles, but it has twice seen oddball radio signals that could be evidence of something even weirder: some heavier particle unknown to physicists’ standard model, burrowing up through Earth. Science writer Adrian Cho joins host Sarah Crespi to discuss the possibility that this reading could lead to a big change in physics. Next, host Meagan Cantwell asks researcher Ben Dalziel what makes a bad—or good—flu year. Traditionally, research has focused on two factors: climate, which impacts how long the virus stays active after a sneeze or cough, and changes in the virus itself, which can influence its infectiousness. But these factors don’t explain every pattern. Dalziel, a population biologist in the Departments of Integrative Biology and Mathematics at Oregon State University in Corvallis, explains how humidity and community size shape the way influenza spreads. This week’s episode was edited by Podigy. Download a transcript of this episode (PDF) Listen to previous podcasts. About the Science Podcast [Image: Stuart Rankin/Flickr; Music: Jeffrey Cook]

A small isolated town in Colombia is home to a large cluster of people with fragile X syndrome—a genetic disorder that leads to intellectual disability, physical abnormalities, and sometimes autism. Spectrum staff reporter Hannah Furfaro joins host Sarah Crespi to discuss the history of fragile X in the town of Ricaurte and the future of the people who live there. Also this week, we talk about greening up grass. Lawns of green grass pervade urban areas all around the world, regardless of climate, but the cost of maintaining them may outweigh their benefits. Host Meagan Cantwell talks with Maria Ignatieva of The University of Western Australia in Perth and the Swedish University of Agricultural Sciences in Uppsala about how lawns can be transformed to contribute to a more sustainable future. This week’s episode was edited by Podigy. Download a transcript of this episode (PDF) Listen to previous podcasts. About the Science Podcast [Image: Adam Kerfoot-Roberts/Flickr; Music: Jeffrey Cook]

As you age, your cells divide over and over again, leading to minute changes in their genomes. New research reveals that in the lining of the esophagus, mutant cells run rampant, fighting for dominance over normal cells. But they do this without causing any detectable damage or cancer. Host Sarah Crespi talks to Phil Jones, a professor of cancer development at the University of Cambridge in the United Kingdom, about what these genome changes can tell us about aging and cancer, and how some of the mutations might be good for you. Most Western farmers apply their pesticides using drones and machinery, but in less developed countries, organophosphate pesticides are applied by hand, resulting in myriad health issues from direct exposure to these neurotoxic chemicals. Host Meagan Cantwell speaks with Praveen Vemula, a research investigator at the Institute for Stem Cell Biology and Regenerative Medicine in Bengaluru, India, about his latest solution—a cost-effective gel that can be applied to the skin to limit pesticide-related toxicity and mortality. This week’s episode was edited by Podigy. Download a transcript of this episode (PDF) Listen to previous podcasts. About the Science Podcast [Image:Navid Folpour/Flickr; Music: Jeffrey Cook]

A group of children is suing the U.S. government—claiming their rights to life, liberty, and property are under threat from climate change thanks to government policies that have encouraged the use and extraction of fossil fuels. Host Meagan Cantwell interviews news writer Julia Rosen on the ins and outs of the suit and what it could mean if the kids win the day.    Also this week, host Sarah Crespi talks with Andrew Moeller of Cornell University about his work tracing the gut microbes inherited through 10 generations of mice. It turns out the fidelity is quite high—you can still tell mice lineages apart by their gut microbes after 10 generations. And horizontally transmitted microbes, those that jump from one mouse line to another through exposure to common spaces or handlers, were more likely than inherited bacteria to be pathogenic and were often linked to illnesses in people. This week’s episode was edited by Podigy. Download a transcript of this episode (PDF) Listen to previous podcasts. About the Science Podcast [Image: Bob Dass/Flickr; Music: Jeffrey Cook] 

A new report suggests a big increase in the use of monkeys in laboratory experiments in the United States in 2017. Online News Editor David Grimm joins host Sarah Crespi to discuss which areas of research are experiencing this rise and the possible reasons behind it. Also this week, host Meagan Cantwell talks with staff writer Adrian Cho about a final push to affix the metric system’s measures to physical constants instead of physical objects. That means the perfectly formed 1-kilogram cylinder known as Le Grand K is no more; it also means that the meter, the ampere, and other units of measure are now derived using complex calculations and experiments.  This week’s episode was edited by Podigy. Download a transcript (PDF) Listen to previous podcasts. About the Science Podcast [Image: Peter Nijenhuis/Flickr; Music: Jeffrey Cook] 

A new Science investigation reveals several major private research funders—including the Wellcome Trust and the Robert Wood Johnson Foundation—are making secretive offshore investments at odds with their organizational missions. Host Meagan Cantwell talks with writer Charles Piller about his deep dive into why some private funders choose to invest in these accounts. In the United States, gun injuries kill more children annually than pediatric cancer, but funding for firearm research pales in comparison. On this week’s show, host Sarah Crespi talks with Staff Writer Meredith Wadman and emergency physician Rebecca Cunningham about how a new grant will jump-start research on gun deaths in children. This week’s episode was edited by Podigy. Listen to previous podcasts. About the Science Podcast [Image: Bernard Spragg; Music: Jeffrey Cook] *Correction, 27 December, 5 p.m.: The interview on studying gun deaths in children in the United States incorrectly says that NIH spent $3.1 million on research into pediatric gun deaths. The correct figure is $4.4 million.

First, we hear Online News Editor David Grimm and host Sarah Crespi discuss audience favorites and staff picks from this year’s online stories, from mysterious pelvises to quantum engines. Megan Cantwell talks with News Editor Tim Appenzeller about the 2018 Breakthrough of the Year, a few of the runners-up, and some breakdowns. See the whole breakthrough package here, including all the runners-up and breakdowns. And in her final segment for the Science Podcast, host Jen Golbeck talks with Science books editor Valerie Thompson about the year in books. Both also suggest some last-minute additions to your holiday shopping list. This week’s episode was edited by Podigy. Download the transcript (PDF) Listen to previous podcasts. About the Science Podcast [Image: NASA Scientific Visualization Studio; Music: Jeffrey Cook]

Plan S, an initiative that requires participating research funders to immediately publish research in an open-access journal or repository, was announced in September 2018 by Science Europe with 11 participating agencies. Several others have signed on since the launch, but other funders and journal publishers have reservations. Host Meagan Cantwell speaks with Contributing Correspondent Tania Rabesandratana about those reservations and how Plan S is trying to change publishing practices and research culture at large. Some 1.7 million Jewish people were murdered by the Nazis in the 22 months of Operation Reinhard (1942–43) which aimed to eliminate all Jews in occupied Poland. But until now, the speed and totality of these murders were poorly understood. It turns out that about one-quarter of all Jews killed during the Holocaust were murdered in the autumn of 1942, during this operation. Meagan talks with Lewi Stone, a professor of biomathematics at Tel Aviv University in Israel and mathematical science at RMIT University in Melbourne, Australia, about this shocking kill rate, and why researchers are taking a quantitative approach to characterizing genocides. This week’s episode was edited by Podigy. Download the transcript (PDF) Listen to previous podcasts. About the Science Podcast [Image: Michael Beckwith; Music: Jeffrey Cook]

Massive Open Online Courses (MOOCs) provide free lectures and assignments, and gained global attention for their potential to increase education accessibility. Plagued with high attrition rates and fewer returning students every year, MOOCs have pivoted to a new revenue model—offering accredited master’s degrees for professionals. Host Meagan Cantwell speaks with Justin Reich, an assistant professor in the Comparative Media Studies Department at the Massachusetts Institute of Technology in Cambridge, about the evolution of MOOCs and how these MOOC professional programs may be reaching a different audience than traditional online education. Archaeologists were flummoxed when they found a brilliant blue mineral in the dental plaque of a medieval-era woman from Germany. It turned out to be lapis lazuli—an expensive pigment that would have had to travel thousands of kilometers from the mines of Afghanistan to a monastery in Germany. Host Sarah Crespi talks to Christina Warinner, a professor of archaeogenetics at the Max Planck Institute for the Science of Human History in Jena, Germany, about how the discovery of this pigment shed light on the impressive life of the medieval woman, an artist who likely played a role in manuscript production. This week’s episode was edited by Podigy. Download the transcript (PDF) Listen to previous podcasts. About the Science Podcast [Image:Oberlin.edu/Wikimedia Commons; Music: Jeffrey Cook]

The “dank” smelling terpenes emitted by growing marijuana can combine with chemicals in car emissions to form ozone, a health-damaging compound. This is especially problematic in Denver, where ozone levels are dangerously high and pot farms have sprung up along two highways in the city. Host Sarah Crespi talks with reporter Jason Plautz about researchers’ efforts to measure terpene emissions from pot plants and how federal restrictions have hampered them. Next, host Meagan Cantwell talks with Dana Small, a professor of psychiatry and psychology at Yale University, about how processed foods are perceived by the body. In a doughnut-rich world, what’s a body to think about calories, nutrition, and satiety? And in the first book segment of the year, books editor Valerie Thompson is joined by Erika Malim, a history professor at Princeton University, to talk about her book Creatures of Cain: The Hunt for Human Nature in Cold War America, which follows the rise and fall of the “killer ape hypothesis”—the idea that our capacity for killing each other is what makes us human. This week’s episode was edited by Podigy. Download the transcript (PDF) Listen to previous podcasts. About the Science Podcast [Image: Wornden LY/Flickr; Music: Jeffrey Cook]

Orla Smith, editor of Science Translational Medicine joins host Sarah Crespi to talk about what has changed in the past 10 years of microbiome research, what’s getting close to being useful in treatment, and how strong, exactly, the research is behind those probiotic yogurts. When you’re sick, sleeping is restorative—it helps your body recover from nasty infections. Meagan Cantwell speaks with Amita Sehgal, professor of neuroscience at the University of Pennsylvania and an investigator at Howard Hughes Medical Institute in Chevy Chase, Maryland, about the process of discovering a gene in fruit flies that links sleep and immune function. This week’s episode was edited by Podigy. Download the transcript (PDF) Listen to previous podcasts. About the Science Podcast [Music: Jeffrey Cook]

Because of its genetic complexity, the potato didn’t undergo a “green revolution” like other staple crops. It can take more than 15 years to breed a new kind of potato that farmers can grow, and genetic engineering just won’t work for tackling complex traits such as increased yield or heat resistance. Host Sarah Crespi talks with Staff Writer Erik Stokstad about how researchers are trying to simplify the potato genome to make it easier to manipulate through breeding. Researchers and companies are racing to perfect an injector pill—a pill that you swallow, which then uses a tiny needle to shoot medicine into the body. Such an approach could help improve compliance for injected medications like insulin. Host Meagan Cantwell and Staff Writer Robert F. Service discuss a new kind of pill—one that flips itself over once it hits the bottom of the stomach and injects a dose of medication into the stomach lining. This week’s episode was edited by Podigy. Download the transcript (PDF) Listen to previous podcasts. About the Science Podcast [Image: Michael Eric Nickel/Flickr; Music: Jeffrey Cook]

New archaeological evidence suggests the same black plague that decimated Europe also took its toll on sub-Saharan Africa. Host Sarah Crespi talks with Contributing Correspondent Lizzie Wade about diverse medieval sub-Saharan cities that shrank or even disappeared around the same time the plague was stalking Europe. In a second archaeological story, Meagan Cantwell talks with Gustavo Politis, professor of archaeology at the National University of Central Buenos Aires and the National University of La Plata, about new radiocarbon dates for giant ground sloth remains found in the Argentine archaeological site Campo Laborde. The team’s new dates suggest humans hunted and butchered ground sloths in the late Pleistocene, about 12,500 years ago. This week’s episode was edited by Podigy. Download the transcript (PDF) Listen to previous podcasts. About the Science Podcast [Image: Ife-Sungbo Archaeological Project; Music: Jeffrey Cook]

Pirate’s gold may not be that far off, as there are valuable metals embedded in potato-size nodules thousands of meters down in the depths of the ocean. Host Meagan Cantwell talks with Staff Writer Paul Voosen about the first deep-sea test of a bus-size machine designed to scoop up these nodules, and its potential impact on the surrounding ecosystem. In an expedition well above sea level, the Hayabusa2 spacecraft touched down on the asteroid Ryugu last month. And although the craft won’t return to Earth until 2020, researchers have learned a lot about Ryugu in the meantime. Meagan speaks with Seiji Sugita, a professor at the University of Tokyo and principal investigator of the Optical Navigation Camera of Hayabusa 2, about Ryugu’s parent body, and how this study can better inform future asteroid missions. This week’s episode was edited by Podigy. Download transcript (PDF) Listen to previous podcasts. About the Science Podcast [Image: Japan Aerospace Exploration Agency; Music: Jeffrey Cook]

Southern California’s famous Santa Anita racetrack is struggling to explain a series of recent horse injuries and deaths. Host Meagan Cantwell is joined by freelance journalist Christa Lesté-Lasserre to discuss what might be causing these injuries and when the track might reopen. In our second segment, researchers are racing to understand the impact of jailing people before trial in the United States. Host Sarah Crespi talks with Online News Editor Catherine Matacic about the negative downstream effects of cash bail—and what research can tell us about other options for the U.S. pretrial justice system. Last up is books, in which we hear about the long, sometimes winding, roads that food can take from its source to your plate. Books editor Valerie Thompson talks with author Robyn Metcalfe about her new work, Food Routes: Growing Bananas in Iceland and Other Tales from the Logistics of Eating. This week’s episode was edited by Podigy. *Correction, 1 April, 12 p.m.: A previous version of this podcast included an additional research technique that was not used to investigate the Santa Anita racetrack. Download the transcript (PDF)  Listen to previous podcasts. About the Science Podcast [Image: Mark Smith/Flickr; Music: Jeffrey Cook]

The ancient humans also known as the “hobbit” people (Homo floresiensis) might have company in their small stature with the discovery of another species of hominin in the Philippines. Host Sarah Crespi talks to Contributing Correspondent Lizzie Wade about what researchers have learned about this hominin from a jaw fragment, and its finger and toe bones and how this fits in with past discoveries of other ancient humans. Also this week, host Meagan Cantwell speaks with Florian Schiestl, a professor in evolutionary biology at the University of Zurich in Switzerland, about his work to understand the rapid evolution of the flowering plant Brassica rapa over the course of six generations. He was able to see how the combination of pollination by bees and risk of getting eaten by herbivores influences the plant’s appearance and defense mechanisms. This week’s episode was edited by Podigy. Ads on this week's show: Kolabtree.com and Magellan TV Listen to previous podcasts. About the Science Podcast [Image: Florian Schiestl; Music: Jeffrey Cook]

Noncancerous tumors of the uterus—also known as fibroids—are extremely common in women. One risk factor, according to the scientific literature, is “black race.” But such simplistic categories may actually obscure the real drivers of the disparities in outcomes for women with fibroids, according to this week’s guest. Host Meagan Cantwell speaks with Jada Benn Torres, an associate professor of anthropology at Vanderbilt University in Nashville, about how using interdisciplinary approaches— incorporating both genetic and cultural perspectives—can paint a more complete picture of how race shapes our understanding of diseases and how they are treated. In our monthly books segment, book review editor Valerie Thompson talks with David Rothenberg, author of the book Nightingales in Berlin: Searching for the Perfect Sound, about spending time with birds, whales, and neuroscientists trying to understand the aesthetics of human and animal music. This week’s episode was edited by Podigy. Download the transcript (PDF) Listen to previous podcasts. About the Science Podcast [Image: Carlos Delgado/Wikipedia; Matthias Ripp/Flickr; Music: Jeffrey Cook]

Humans have sought new materials to make elusive blue pigments for millennia—with mixed success. Today, scientists are tackling this blue-hued problem from many different angles. Host Sarah Crespi talks with contributing correspondent Kai Kupferschmidt about how scientists are looking to algae, bacteria, flowers—even minerals from deep under Earth’s crust—in the age-old quest for the rarest of pigments. Also this week, host Meagan Cantwell speaks with Andrew Whitehead, associate professor in the department of environmental toxicology at the University of California, Davis, about how the Atlantic killifish rescued its cousin, the gulf killifish, from extreme pollution. Whitehead talks about how a gene exchange occurred between these species that normally live thousands of kilometers apart, and whether this research could inform future conservation efforts. This week’s episode was edited by Podigy Download the transcript (PDF) Ads on this show: KiwiCo Listen to previous podcasts. About the Science Podcast

The groundwater of Rockford, Michigan, is contaminated by per- and polyfluoroalkyl substances, chemicals found in everything from nonstick pans to dental floss to—in the case of Rockford—waterproofing agents from a shoe factory that shut down in 2009. Science journalist Sara Talpos talks with host Meagan Cantwell about how locals found the potentially health-harming chemicals in their water, and how contamination from nonstick chemicals isn’t limited to Michigan. Also this week, host Sarah Crespi talks with Shyamnath Gollakota of the University of Washington in Seattle about his work diagnosing ear infections with smartphones. With the right app and a small paper cone, it turns out that your phone can listen for excess fluid in the ear by bouncing quiet clicks from the speaker off the eardrum. Clinical testing shows the setup is simple to use and can help parents and doctors check children for this common infection. This week’s episode was edited by Podigy. Ads on this show: Science Rules! podcast with Bill Nye Download the transcript (PDF)  Listen to previous podcasts. About the Science Podcast [Image: Dennis Wise/University of Washington; Music: Jeffrey Cook]

The Large Hadron Collider (LHC) was built with one big goal in mind: to find the Higgs boson. It did just that in 2012. But the question on many physicists’ minds about the LHC is, “What have you done for me lately?” Host Sarah Crespi talks with Staff Writer Adrian Cho about proposals to look at the showers of particles created by its proton collisions in new ways—from changing which events are recorded, to changing how the data are analyzed, even building more detectors outside of the LHC proper—all in the hopes that strange, longer-lived particles are being generated but missed by the current set up. Also this week, Sarah talks with Tian Li of the University of Maryland in College Park about a modified wood designed to passively cool buildings. Starting from its humble roots in the forest, the wood is given a makeover: First it is bleached white to eliminate pigments that absorb light. Next, it is hot pressed, which adds strength and durability. Most importantly, these processes allow the wood to emit in the middle-infrared range, so that when facing the sky, heat passes through the wood out to the giant heat sink of outer space. This week’s episode was edited by Podigy. Download a transcript (PDF) Listen to previous podcasts. About the Science Podcast

How can you resist puppy dog eyes? This sweet, soulful look might very well have been bred into canines by their intended victims—humans. Online News Editor David Grimm talks with host Meagan Cantwell about a new study on the evolution of this endearing facial maneuver. David also talks about what diseased dog spines can tell us about early domestication—were these marks of hard work or a gentler old age for our doggy domestics? Also this week, host Sarah Crespi talks with Michel Marechal of the University of Zurich in Switzerland about honesty around the globe. By tracking about 17,000 wallets left at hotels, post offices, and banks, his team found that we humans are a lot more honest than either economic models or our own intuitions give us credit for. This week’s episode was edited by Podigy. Ads on the show: MagellanTV Download a transcript (PDF) Listen to previous podcasts. About the Science Podcast [Image: Molly Marshall/Flickr; Music: Jeffrey Cook]

Researchers have been making animal embryos from two different species, so-called “chimeras,” for years, by introducing stem cells from one species into a very early embryo of another species. The ultimate goal is to coax the foreign cells into forming an organ for transplantation. But questions abound: Can evolutionarily distant animals, like pigs and humans, be mixed together to produce such organs? Or could species closely related to us, like chimps and macaques, stand in for tests with human cells? Staff Writer Kelly Servick joins host Sarah Crespi to discuss the research, the regulations, and the growing ethical debate. Also this week, Sarah talks with Yossi Yovel of the School of Zoology and the Sagol School of Neuroscience at Tel Aviv University in Israel about his work on sensory integration in bats. Writing in Science Advances, he and his colleagues show through several clever experiments when bats switch between echolocation and vision. Yossi and Sarah discuss how these trade-offs in bats can inform larger questions about our own perception. For our monthly books segment, Science books editor Valerie Thompson talks with Lucy Jones of the Seismological Laboratory at the California Institute of Technology in Pasadena about a song she created, based on 130 years of temperature data, for an instrument called the “viola de gamba.” Read more on the Books et al. blog. Download a transcript (PDF) This week’s episode was edited by Podigy. Ads on the show: MagellanTV; KiwiCo Listen to previous podcasts. About the Science Podcast [Image: The Legend Kay/Flickr; Music: Jeffrey Cook]

Chemists have long known how to convert carbon dioxide into fuels—but up until now, such processes have been too expensive for commercial use. Staff Writer Robert Service talks with host Sarah Crespi about using new filters and catalysts to close the gap between air-derived and fossil-derived gasoline.   Also this week, host Sarah Crespi talks with Nitish Padmanaban of Stanford University in Palo Alto, California, about replacing bifocals with “autofocals.” These auto-focusing glasses track your eye position and measure the distance to the visual target before adjusting the thickness of their liquid lenses. The prototype glasses have an onboard camera and batteries that make them particularly bulky; however, they still outperformed progressive lenses in tests of focus speed and acuity. This week’s episode was edited by Podigy.   Download a transcript (PDF) Listen to previous podcasts.   About the Science Podcast