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Cloud Computing - CLOUD 2019 : 12th International Conference, held as part of the Services Conference Federation, SCF 2019, San Diego, CA, USA, June 25-30, 2019 ; proceedings / Dilma Da Silva, Qingyang Wang, Liang-Jie Zhang (eds.)

By prospero.murdoch.edu.au
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CLOUD (Conference) (12th : 2019 : San Diego, Calif.)

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Advances in internet, data and web technologies : the 7th International Conference on Emerging Internet, Data and Web Technologies (EIDWT-2019) / Leonard Barolli, Fatos Xhafa, Zahoor Ali Khan, Hamad Odhabi, editors

By prospero.murdoch.edu.au
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International Conference on Emerging Internet, Data and Web Technologies (7th : 2019 : United Arab Emirates)

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Advances in network-based information systems : the 21st International Conference on Network-Based Information Systems (NBiS-2018) / Leonard Barolli, Natalia Kryvinska, Tomoya Enokido, Makoto Takizawa, editors

By prospero.murdoch.edu.au
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NBiS (Conference) (21st : 2018 : Bratislava, Slovakia)

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Recent advances in computer vision : theories and applications / Mahmoud Hassaballah, Khalid M. Hosny, editors

By prospero.murdoch.edu.au
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Computer ethics : cautionary tales and ethical dilemmas in computing / Tom Forester and Perry Morrison

By prospero.murdoch.edu.au
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Forester, Tom

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Emerging technologies in computing : Second International Conference, iCETiC 2019, London, UK, August 19-20, 2019 : proceedings / Mahdi H. Miraz, Peter S. Excell, Andrew Ware, Safeeullah Soomro, Maaruf Ali (eds.)

By prospero.murdoch.edu.au
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09/21:11 EST Bush Walkers Weather Alert for Western and Central Plateau forecast districts

By www.bom.gov.au
Published On :: Sat, 09 May 2020 11:11:43 GMT

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Income Splitting: Opportunities and Pitfalls

By www.cch.ca
Published On :: Mon, 07 Jul 2014 09:28:21 GMT

In this webinar, the tax lawyers of Minden Gross LLP will provide a practical overview of income splitting strategies available today. This webinar will review in detail the various attribution rules devised to thwart income planning, and guide participants to strategies still available for safe and effective income splitting.

Available Sessions for this Seminar:

May 12, 2015 12:00 PM - 2:00 PM EST

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Foreign Affiliates - What Advisors to Owner/Manager Clients Need to Know

By www.cch.ca
Published On :: Fri, 28 Nov 2014 11:55:15 GMT

Join the tax lawyers of Dentons Canada LLP for an instructive overview and update of the tax rules in respect of foreign affiliates. Cross border holdings and debt require special consideration in tax filing, and Canada’s foreign affiliate tax regime has undergone some significant changes in the past couple of years. This webinar will examine the basics of Canada’s foreign affiliate taxation regime - as it applies to small and medium enterprises (SMEs) – who already carry an international presence, or are considering expansion abroad.

Available Sessions for this Seminar:

January 21, 2015 12:00 PM - 2:00 PM EST

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NHAI to resume toll collection on national highways from April 20

By economictimes.indiatimes.com
Published On :: 2020-04-17T22:54:40+05:30

Replying to a letter from NHAI, the ministry said the NHAI in letters dated April 11 and 14 has highlighted reasons for resuming the collection of user fee on national highways, saying that the Ministry of Home Affairs has allowed a lot of activities with effect from April 20, including commercial and private establishments and construction activities.

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NHAI to resume toll collection on National highways from April 20

By economictimes.indiatimes.com
Published On :: 2020-04-18T11:05:44+05:30

Besides construction activity, the home ministry has allowed commercial and private establishments to resume operations. Toll collection falls under this category. Interstate and intra-state movement of all trucks and other goods or carrier vehicles has also been allowed.

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NHAI turns lockdown into opportunity to redress disputes worth Rs 80,000 crore

By economictimes.indiatimes.com
Published On :: 2020-04-19T16:59:34+05:30

Sandhu and other top brass of the National Highways Authority of India (NHAI) have been on an inspection spree of projects, taking the benefit of no traffic on otherwise congested highways. NHAI, an official said, has at least 180 cases in arbitration involving a sum of about Rs 80,000 crore.

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Transporters say not able to sustain highway toll charges

By economictimes.indiatimes.com
Published On :: 2020-04-19T18:15:05+05:30

The All India Motor Transport Congress (AIMTC), the apex body for transporters that represents about 95 lakh truckers and transport entities, sought suspension of toll till May 3.

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Toll collection resumes on National Highways

By economictimes.indiatimes.com
Published On :: 2020-04-20T10:40:16+05:30

National Highways Authority of India (NHAI) as well as highway developers resumed collection at toll plazas. Highways developer IRB Infrastructure Developers said all its Special Purpose Vehicles (SPVs) "have resumed their toll collection from 00.00 hours today" in line with the NHAI directives.

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NHAI resumes toll collection amid resistance from truck operators

By economictimes.indiatimes.com
Published On :: 2020-04-21T10:40:12+05:30

The ministry of road transport and highways had on Friday asked NHAI to prepare for resumption of toll operations, noting that user fee collection contributes to the government exchequer and also provides financial strength to NHAI in terms of budgetary support.

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70% Highway projects resume after partial lifting of lockdown

By economictimes.indiatimes.com
Published On :: 2020-04-23T07:26:04+05:30

As the ministry of home affairs (MHA) made way for lifting curbs on certain sectors to get economic activity restarted, construction activity is still crawling, though it has started across various districts.

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Government looking into possibility of building smart cities along Delhi-Mumbai Expressway: Nitin Gadkari

By economictimes.indiatimes.com
Published On :: 2020-04-29T20:02:29+05:30

"The government is looking if NHAI can plan a township along the highway (Delhi-Mumbai Expressway) ... a Cabinet note has been floated for this," Road Transport, Highways and MSME Minister Gadkari said during an interaction with real estate body NAREDCO via a video conference.

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Spadework for central secretariats in states begins

By economictimes.indiatimes.com
Published On :: 2020-04-30T07:55:54+05:30

The Central Public Works Department has been entrusted with the job of construction of secretariats which would be developed as a high security office on the lines of Delhi’s CGO Complex. It would have public dealing offices for central ministries and even accommodate ministries which have been looking for office space in states.

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Delhi-Amritsar-Katra Expressway to pass through Amritsar: Harsimrat Kaur Badal

By economictimes.indiatimes.com
Published On :: 2020-04-30T10:43:58+05:30

Food processing industries minister Harsimrat Kaur Badal on Thursday said that one section of the Delhi-Amritsar-Katra Expressway would pass through Amritsar after being split into two at Kartarpur even as the other section would go through Gurdaspur to Katra.

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NCLT approves Ebix’s revival plan for Trimax IT Infrastructure

By economictimes.indiatimes.com
Published On :: 2020-05-06T21:38:07+05:30

Ebix Software India (ESIPL) will pay upfront Rs 75 crore to acquire the company. The company owed over Rs 1,918 crore to its lenders, including about Rs 1,700 crore to financial creditors.

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Synthesis, evaluation and molecular modelling of piceatannol analogues as arginase inhibitors

By feeds.rsc.org
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RSC Med. Chem., 2020, Advance Article
DOI: 10.1039/D0MD00011F, Research Article

J. Muller, B. Cardey, A. Zedet, C. Desingle, M. Grzybowski, P. Pomper, S. Foley, D. Harakat, C. Ramseyer, C. Girard, M. Pudlo
A quantum chemistry guided optimisation (leading to piceatannol analogue 3t) with a good understanding of the catechol binding mode to the bimanganese cluster of arginase.
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Recent progress on phenotype-based discovery of dengue inhibitors

By feeds.rsc.org
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RSC Med. Chem., 2020, Advance Article
DOI: 10.1039/D0MD00052C, Review Article

Fumiaki Yokokawa
The review presents the discovery of new dengue inhibitors by a phenotype-based approach.
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Synthesis and 18F-radiolabeling of thymidine AMBF3 conjugates

By feeds.rsc.org
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RSC Med. Chem., 2020, Advance Article
DOI: 10.1039/D0MD00054J, Research Article

Antonio A. W. L. Wong, Jerome Lozada, Mathieu L. Lepage, Chengcheng Zhang, Helen Merkens, Jutta Zeisler, Kuo-Shyan Lin, François Bénard, David M. Perrin
One step radiofluorination of two thymidine bioconjugates for positron emission tomography (PET) imaging; proof concept with clinical-grade ¹⁸F-labeling and preliminary mouse images.
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Discovery, SAR study and ADME properties of methyl 4-amino-3-cyano-1-(2-benzyloxyphenyl)-1H-pyrazole-5-carboxylate as an HIV-1 replication inhibitor

By feeds.rsc.org
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RSC Med. Chem., 2020, Advance Article
DOI: 10.1039/D0MD00025F, Research Article

Jeanne Fichez, Cathia Soulie, Laurent Le Corre, Sophie Sayon, Stéphane Priet, Karine Alvarez, Olivier Delelis, Patrick Gizzi, Guillaume Prestat, Christine Gravier-Pelletier, Anne-Geneviève Marcelin, Vincent Calvez, Patricia Busca
Identified as an HIV-1 inhibitor in cellulo, this pyrazole does not belong to the three main classes of anti HIV-drugs, a feature of prime interest in the context of viral resistance.
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Protein—fragment complex structures derived by NMR Molecular Replacement

By feeds.rsc.org
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RSC Med. Chem., 2020, Accepted Manuscript
DOI: 10.1039/D0MD00068J, Research Article

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Felix Torres, Dhiman Ghosh, Dean Strotz, Celestine Chi, Ben Davis, Julien Orts
Recently we have established an NMR Molecular Replacement method, which is capable of solving the structure of the interaction site of protein-ligand complexes in a fully automated manner. While the...
The content of this RSS Feed (c) The Royal Society of Chemistry

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Cyclic boronates as versatile scaffolds for KPC-2 β-lactamase inhibition

By feeds.rsc.org
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RSC Med. Chem., 2020, 11,491-496
DOI: 10.1039/C9MD00557A, Research Article

Catherine L. Tooke, Philip Hinchliffe, Alen Krajnc, Adrian J. Mulholland, Jürgen Brem, Christopher J. Schofield, James Spencer
Mono- (vaborbactam) and bi-cyclic (taniborbactam) boronate inhibitors bind KPC-2 similarly, but the latter is essentially irreversible.
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Vascular tone and angiogenesis modulation by catecholamine coordinated to ruthenium

By feeds.rsc.org
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RSC Med. Chem., 2020, 11,497-510
DOI: 10.1039/C9MD00573K, Research Article

Jacqueline Querino Alves, Laena Pernomian, Cássia Dias Silva, Mayara Santos Gomes, Ana Maria de Oliveira, Roberto Santana da Silva
The interaction of catecholamine site to receptors drives the proangiogenic to antiangiogenic character.
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Recent progress in selective estrogen receptor downregulators (SERDs) for the treatment of breast cancer

By feeds.rsc.org
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RSC Med. Chem., 2020, 11,438-454
DOI: 10.1039/C9MD00570F, Review Article

Shagufta, Irshad Ahmad, Shimy Mathew, Sofia Rahman
This article reviews the current progress in the development of SERDs as anti-breast cancer agents.
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Arylsulfonyl histamine derivatives as powerful and selective α-glucosidase inhibitors

By feeds.rsc.org
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RSC Med. Chem., 2020, 11,518-527
DOI: 10.1039/C9MD00559E, Research Article

M. I. Osella, M. O. Salazar, M. D. Gamarra, D. M. Moreno, F. Lambertucci, D. E. Frances, R. L. E. Furlan
N ^α,N^τ-Di-4-trifluorobenzenesulfonyl histamine inhibits α-glucosidase in vitro reversibly and selectively with a K_i value of 11.6 μM, and shows an in vivo hypoglycemic effect in mice.
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Unveiling the active isomer of cycloalanopine, a cyclic opine from Lactobacillus rhamnosus LS8, through synthesis and analog production

By feeds.rsc.org
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RSC Med. Chem., 2020, 11,528-531
DOI: 10.1039/D0MD00033G, Research Article

Isaac Antwi, Sorina Chiorean, Marco J. van Belkum, John C. Vederas
Stereochemistry of the antimicrobial isomer of a cyclic opine was determined by synthesis using oxidative cyclisation of a bis-hydrazide.
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Computer-aided discovery of phenylpyrazole based amides as potent S6K1 inhibitors

By feeds.rsc.org
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RSC Med. Chem., 2020, Advance Article
DOI: 10.1039/C9MD00537D, Research Article

Yan Yin, Yuxing Sun, Lianhua Zhao, Jinpeng Pan, Yangbo Feng
Ribosomal protein S6 kinase beta-1 (S6K1) is an attractive therapeutic target.
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On this Day: F1 legend Senna dies

By www.rediff.com
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Much has been written about that afternoon, and the Brazilian's career and epic rivalry with Frenchman Alain Prost, with questions still asked about what caused the crash. What is certain is that it changed Formula One, triggering a major safety review and altering the course of sporting history.

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Albon denies Leclerc a virtual F1 'trick

By www.rediff.com
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The Thai's victory over his Ferrari rival gave Red Bull something to celebrate on a day that should have seen the return of Max Verstappen's home Dutch Grand Prix after a 35-year absence.

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Resilient space systems design: an introduction.

By library.mit.edu
Published On :: Sun, 16 Feb 2020 06:19:41 EST

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Reducing operational costs in composites manufacturing / by Karen Snyder Travis

By library.mit.edu
Published On :: Sun, 16 Feb 2020 06:19:41 EST

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Principles of reinforced concrete design / Mete A. Sozen, Toshikatsu Ichinose, Santiago Pujol

By library.mit.edu
Published On :: Sun, 16 Feb 2020 06:19:41 EST

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Internet of vehicles: technologies and services toward smart cities: 6th International Conference, IOV 2019, Kaohsiung, Taiwan, November 18-21, 2019, Proceedings / Ching-Hsien Hsu, Sondès Kallel, Kun-Chan Lan, Zibin Zheng (eds.)

By library.mit.edu
Published On :: Sun, 16 Feb 2020 06:19:41 EST

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Rütteldruckverdichtung als Plastodynamisches Problem: Deep vibration compaction as plastodynamic problem / W. Fellin

By library.mit.edu
Published On :: Sun, 16 Feb 2020 06:19:41 EST

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