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Physician-Parents Whose Children Have Rare Diseases

By jamanetwork.com
Published On :: Tue, 05 May 2020 00:00:00 GMT

In this essay, a critical care pediatric hospitalist finds herself on the other side of the office table advocating for the specific medical care needed to address her son’s rare skeletal dysplasia and her search for a pediatric specialist with whom to travel on this quest.


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A Medical Student Shares Her Struggle With Depression

By jamanetwork.com
Published On :: Tue, 05 May 2020 00:00:00 GMT

In this essay, a young medical student describes her struggle with depression and how the experience of vulnerability has bred a deep compassion for her patients and peers.


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Friendships Across Cultural Barriers—We Are All the Same

By jamanetwork.com
Published On :: Tue, 05 May 2020 00:00:00 GMT

In this narrative medicine essay, a family practitioner tells the story of how her relationship with an old-order Mennonite woman whose newborn son she examined and took to the hospital for cardiac surgery one Christmas day turns to friendship and a relationship with her broader community when the woman stays with her during her newborn daughter’s cardiac surgery.


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Reflections on Women in Leadership—Holding up Half

By jamanetwork.com
Published On :: Tue, 05 May 2020 00:00:00 GMT

In this narrative medicine essay, a medical school dean talks about the reticence most women feel when considering leadership roles and urges women to work out of their comfort zones, seize diverse opportunities, and step into leadership roles.


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The Sound of Silence—When There Are No Words

By jamanetwork.com
Published On :: Tue, 05 May 2020 00:00:00 GMT

In this narrative medicine essay, a surgeon and palliative care physician describes the isolating silence that she felt her after the slaying of her father in Egypt when she was 18 years old and how that lingering silence has come to guide her when sitting with patients, when there are no words.


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A dual-targeted CeO2–DNA nanosensor for real-time imaging of H2O2 to assess atherosclerotic plaque vulnerability

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2020, 8,3502-3505
DOI: 10.1039/C9TB02459J, Communication
Zhenhua Liu, Yujie Cao, Xiaona Zhang, Huazhen Yang, Yujie Zhao, Wen Gao, Bo Tang
A novel dual-targeted CeO2–DNA nanosensor by modifying with folic acid (FA) and CD36 antibody was designed.
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Electrodeposition of nickel nanostructures using silica nanochannels as confinement for low-fouling enzyme-free glucose detection

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2020, 8,3616-3622
DOI: 10.1039/C9TB02472G, Paper
Jialian Ding, Xinru Li, Lin Zhou, Rongjie Yang, Fei Yan, Bin Su
This work reports an enzyme-free glucose sensor based on nickel nanostructures electrodeposited on a fluorine-doped tin oxide (FTO) electrode modified with a silica nanochannel membrane (SNM).
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Aggregation-induced emission luminogens for RONS sensing

By pubs.rsc.org
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J. Mater. Chem. B, 2020, 8,3357-3370
DOI: 10.1039/C9TB02310K, Review Article
Jun Dai, Chong Duan, Yu Huang, Xiaoding Lou, Fan Xia, Shixuan Wang
The development of AIE bioprobes for RONS sensing in living systems is now summarized. We discuss some representative examples of AIEgen based bioprobes in terms of their molecular design, sensing mechanism and sensitive sensing in vitro and in vivo.
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Graphene–nucleic acid biointerface-engineered biosensors with tunable dynamic range

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2020, 8,3623-3630
DOI: 10.1039/C9TB02388G, Paper
Zhifeng Zhao, Hao Yang, Wenyue Zhao, Sha Deng, Kaixiang Zhang, Ruijie Deng, Qiang He, Hong Gao, Jinghong Li
Programmed biosensors with tunable quantification range and higher specificity have been constructed by engineering graphene–nucleic acid biointerfaces.
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Recent advances of tissue-interfaced chemical biosensors

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2020, 8,3371-3381
DOI: 10.1039/C9TB02476J, Review Article
Chuanrui Chen, Yue Guo, Peining Chen, Huisheng Peng
This review discusses recent advances of tissue interfaced chemical biosensors, highlights current challenges and gives an outlook on future possibilities.
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Stretchable gold fiber-based wearable electrochemical sensor toward pH monitoring

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2020, 8,3655-3660
DOI: 10.1039/C9TB02477H, Paper
Ren Wang, Qingfeng Zhai, Yunmeng Zhao, Tiance An, Shu Gong, Zhirui Guo, QianQian Shi, Zijun Yong, Wenlong Cheng
A stretchable gold fiber-based wearable electrochemical pH two-electrodes sensing system for human health monitoring.
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Nucleoside-based fluorescent carbon dots for discrimination of metal ions

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2020, 8,3640-3646
DOI: 10.1039/C9TB02758K, Paper
Tieli Zhou, Jinyi Zhang, Biwu Liu, Shihong Wu, Peng Wu, Juewen Liu
Using nucleosides and citrate as starting materials, a series of fluorescent carbon dots were synthesized showing different quenching properties by metal ions for their detection by a sensor array.
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Boosting biomolecular interactions through DNA origami nano-tailored biosensing interfaces

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2020, 8,3606-3615
DOI: 10.1039/C9TB02439E, Paper
Iene Rutten, Devin Daems, Jeroen Lammertyn
Nano-tailored DNA origami designs nanostructure the bioreceptor layer of encoded microparticles in an innovative microfluidic platform, hereby boosting biomolecular interactions.
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Recent development of biofuel cell based self-powered biosensors

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2020, 8,3393-3407
DOI: 10.1039/C9TB02428J, Review Article
Shuai Hao, Xiaoxuan Sun, He Zhang, Junfeng Zhai, Shaojun Dong
BFC-based SPBs have been used as power sources for other devices and as sensors for detecting toxicity and BOM.
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From design to applications of stimuli-responsive hydrogel strain sensors

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2020, 8,3171-3191
DOI: 10.1039/C9TB02692D, Review Article
Dong Zhang, Baiping Ren, Yanxian Zhang, Lijian Xu, Qinyuan Huang, Yi He, Xuefeng Li, Jiang Wu, Jintao Yang, Qiang Chen, Yung Chang, Jie Zheng
Stimuli-responsive hydrogel strain sensors that synergize the advantages of both hydrogel and smart functional materials have attracted increasing interest from material design to emerging applications in health monitors and human–machine interfaces.
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Flexible and stretchable dual mode nanogenerator for rehabilitation monitoring and information interaction

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2020, 8,3647-3654
DOI: 10.1039/C9TB02466B, Paper
Zhuo Liu, Qiang Zheng, Yue Shi, Lingling Xu, Yang Zou, Dongjie Jiang, Bojing Shi, Xuecheng Qu, Hu Li, Han Ouyang, Ruping Liu, Yuxiang Wu, Yubo Fan, Zhou Li
Sensors with flexibility and stretchability are the key functional modules of converter between mechanical motions and electric signals for intelligent robots and rehabilitation training systems.
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Structurally coloured contact lens sensor for point-of-care ophthalmic health monitoring

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2020, 8,3519-3526
DOI: 10.1039/C9TB02389E, Paper
Yunlong Wang, Qilong Zhao, Xuemin Du
A structurally coloured contact lens sensor has been developed for point-of-care diagnosis of eye diseases.
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Aptamer-based nanostructured interfaces for the detection and release of circulating tumor cells

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2020, 8,3408-3422
DOI: 10.1039/C9TB02457C, Review Article
Pi Ding, Zhili Wang, Zeen Wu, Weipei Zhu, Lifen Liu, Na Sun, Renjun Pei
This paper summarizes various aptamer-functionalized nanostructured interfaces for the detection and release of circulating tumor cells.
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Novel perylene probe-encapsulated metal–organic framework nanocomposites for ratiometric fluorescence detection of ATP

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2020, 8,3661-3666
DOI: 10.1039/C9TB02319D, Paper
Xiaomeng Zhou, Juanmin Li, Li-Li Tan, Qiang Li, Li Shang
Schematic illustration of PDI@ZIF-8 nanocomposite synthesis and ratiometric fluorescence assay for ATP sensing. 2-MIm: 2-methylimidazole.
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Nanomaterial-based gas sensors used for breath diagnosis

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2020, 8,3231-3248
DOI: 10.1039/C9TB02518A, Review Article
Xinyuan Zhou, Zhenjie Xue, Xiangyu Chen, Chuanhui Huang, Wanqiao Bai, Zhili Lu, Tie Wang
Gas-sensing applications commonly use nanomaterials (NMs) because of their unique physicochemical properties, including a high surface-to-volume ratio, enormous number of active sites, controllable morphology, and potential for miniaturisation.
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Stretchable and tough conductive hydrogels for flexible pressure and strain sensors

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2020, 8,3437-3459
DOI: 10.1039/C9TB02570G, Review Article
Zhenwu Wang, Yang Cong, Jun Fu
This review summarises recent advances in stretchable and tough conductive hydrogel sensors for wearable and implantable devices.
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Enhanced biosensing strategies using electrogenerated chemiluminescence: recent progress and future prospects

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2020, 8,3192-3212
DOI: 10.1039/C9TB02578B, Review Article
Rashaad A. Husain, Snigdha Roy Barman, Subhodeep Chatterjee, Imran Khan, Zong-Hong Lin
An overview of enhancement strategies for highly sensitive ECL-based sensing of bioanalytes enabling early detection of cancer.
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A perylenetetracarboxylic dianhydride and aniline-assembled supramolecular nanomaterial with multi-color electrochemiluminescence for a highly sensitive label-free immunoassay

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2020, 8,3676-3682
DOI: 10.1039/C9TB02368B, Paper
Wei Zhang, Yue Song, Yunyun Wang, Shuijian He, Lei Shang, Rongna Ma, Liping Jia, Huaisheng Wang
A novel multi-color ECL nanomaterial assembled from 3,4,9,10-perylenetetracarboxylic dianhydride (PTCDA) and aniline (An) was used for highly sensitive label-free CEA detection.
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Toehold-regulated competitive assembly to accelerate the kinetics of graphene oxide-based biosensors

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2020, 8,3683-3689
DOI: 10.1039/C9TB02454A, Paper
Huan Du, Junbo Chen, Jie Zhang, Rongxing Zhou, Peng Yang, Xiandeng Hou, Nansheng Cheng
With toehold-regulation, the kinetics of graphene oxide-based biosensors can be accelerated.
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Development of CeO2 nanodot encrusted TiO2 nanoparticles with reduced photocatalytic activity and increased biocompatibility towards a human keratinocyte cell line

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2020, Advance Article
DOI: 10.1039/D0TB00629G, Paper
Alexander Morlando, Marcela Chaki Borrás, Yaser Rehman, Shahnaz Bakand, Philip Barker, Ronald Sluyter, Konstantin Konstantinov
Low photocatalytic CeO2/TiO2 nanocomposite particles with high UV attenuation and reduced ROS generation for application in sunscreen products.
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Recent progress of SERS optical nanosensors for miRNA analysis

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2020, Accepted Manuscript
DOI: 10.1039/D0TB00280A, Review Article
Yudie Sun, lin shi, Lan Mi, Ruiyan Guo, Tao Li
This review focus on emerging applications of surface-enhanced Raman spectroscopy (SERS) optical nanosensors for miRNA analysis, in which the key enhancement factors of SERS signal, i.e. SERS-active substrates, SERS nanoprobes...
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Mechanically robust enzymatic degradable shape memory polyurethane urea with rapid recovery response induced by NIR

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2020, Accepted Manuscript
DOI: 10.1039/D0TB00798F, Paper
Xin Li, Wenkai Liu, Yaomin Li, Wanling Lan, Daiguo Zhao, Hecheng Wu, Yuan Feng, Xueling He, Zhen Li, Jiehua Li, Feng Luo, Hong Tan
Biodegradable shape memory polymers have great potential using in minimally invasive surgical procedures. Herein, a series of shape memory polyurethanes (SMPUs) containing chymotrypsin-inspired chain extenders with adjustable mechanical properties and...
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Development of mucoadhesive cationic polypeptide micelles for sustained cabozantinib release and inhibition of corneal neovascularization

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2020, Accepted Manuscript
DOI: 10.1039/D0TB00874E, Paper
Haijie Han, Qichuan Yin, Xiajing Tang, Xiaoning Yu, Qiang Gao, Yelei Tang, Andrzej Grzybowski, Ke Yao, Jian Ji, Xingchao Shentu
Corneal neovascularization (CNV) is one of the leading risk factors for vision loss. Anti-angiogenic drugs can theoretically be extended to the treatment of CNV. However, the application of these drugs...
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The rise of bio-inspired polymer compartments responding to pathology related signals

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2020, Accepted Manuscript
DOI: 10.1039/D0TB00475H, Perspective
Open Access
Luisa Zartner, Moritz Sylvester Muthwill, Ionel Adrian Dinu, Cora-Ann Schoenenberger, Cornelia G. Palivan
Self-organized nano- and microscale polymer compartments (polymersomes, GUVs, PICsomes and LbL capsules) have increasing potential in many sensing applications. In this review, we highlight the key role they play in...
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Multi-Stimuli Responsive Polymeric Prodrug Micelles for Combined Chemotherapy and Photodynamic Therapy

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2020, Accepted Manuscript
DOI: 10.1039/D0TB00539H, Paper
Cheng Hu, Weihua Zhuang, Tao Yu, Liang Chen, Zhen Liang, Gaocan Li, Yunbing Wang
Nowadays, cancer therapy faces severe challenges on boosting therapeutic efficiency and reducing the side effects of drugs. To overcome these challenges, herein multifunctional polymeric prodrug micelles with combining chemotherapy and...
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Thin platelet-like COF nanocomposites for blood brain barrier transport and inhibition of brain metastasis from renal cancer

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2020, Advance Article
DOI: 10.1039/D0TB00724B, Paper
Guiyang Zhang, Bo Jiang, Chunyong Wu, Yanfeng Liu, Yidan He, Xin Huang, Wei Chen, Kai Xi, Hongqian Guo, Xiaozhi Zhao, Xudong Jia
A drug-loaded polymer–COF nanocomposite has been developed to cross the blood brain barrier and treat brain metastasis from renal cancer.
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Bioinspired polydopamine nanoparticles: synthesis, nanomechanical properties, and efficient PEGylation strategy

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2020, Advance Article
DOI: 10.1039/C9TB02769F, Paper
Islam Zmerli, Jean-Philippe Michel, Ali Makky
We established tightly controlled experimental conditions to synthesize polydopamine nanoparticles with well-defined and reproducible physicochemical properties such as size, yield and nanomechanics.
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Phosphates-responsive 2D-Metal─Organic-Framework-Nanozymes for Colorimetric Detection of Alkaline Phosphatase

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2020, Accepted Manuscript
DOI: 10.1039/C9TB02542A, Paper
Xiaoyu Wang, Xiaoqian Jiang, Hui Wei
In this study, a simple colorimetric method with tunable dynamic range for alkaline phosphatase (ALP) activity assay was developed by using peroxidase-mimicking two-dimensional-metal─organic-framework (2D-MOF). Phosphates including pyrophosphate (PPi), ATP, and...
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Unique Sequence-Dependent Properties of Trinucleotide Repeat Monolayers: Electrochemical, Electrical, and Topographic Characterization

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2020, Accepted Manuscript
DOI: 10.1039/D0TB00507J, Paper
Narges Asefifeyzabadi, Motahareh Taki, Madison Funneman, Tingjie Song, Mohtashim Hassan Shamsi
Trinucleotide repeat (TNR) sequences widely exist in nature and their overgrowth is associated with two dozen neurodegenerative diseases in humans. These sequences have unique helical flexibility which affects their biophysical...
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In vivo immunological response of exposure to PEGylated graphene oxide via intraperitoneal injection

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2020, Advance Article
DOI: 10.1039/D0TB00499E, Paper
Zhaowen Ding, Nana Luo, Hua Yue, Yongjun Gao, Guanghui Ma, Wei Wei
2D PEGylated graphene oxide showed stealth-but-immune-activating capacity on macrophages, along with specific intraperitoneal immunological response in vivo.
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A waterborne polyurethane 3D scaffold containing PLGA with a controllable degradation rate and an anti-inflammatory effect for potential applications in neural tissue repair

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2020, Advance Article
DOI: 10.1039/D0TB00656D, Paper
Bohong Du, Hang Yin, Yue Chen, Weiwei Lin, Yanchao Wang, Daiguo Zhao, Gang Wang, Xueling He, Jiehua Li, Zhen Li, Feng Luo, Hong Tan, Qiang Fu
3D connected porous LGPU scaffolds with adjustable degradation and a strong anti-inflammatory effect were prepared for neural tissue repair.
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Glutathione- and light-controlled generation of singlet oxygen for triggering drug release in mesoporous silica nanoparticles

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2020, Advance Article
DOI: 10.1039/D0TB00636J, Paper
Roy C. H. Wong, Dennis K. P. Ng, Wing-Ping Fong, Pui-Chi Lo
An activatable phthalocyanine-based photosensitiser and a singlet-oxygen-triggered doxorubicin releasing system have been incorporated into mesoporous silica nanoparticles, which can release the encapsulated doxorubicin in a controllable manner.
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Multivalent cationic dendrofullerenes for gene transfer: synthesis and DNA complexation

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2020, Advance Article
DOI: 10.1039/D0TB00113A, Paper
Beatriz M. Illescas, Alfonso Pérez-Sánchez, Araceli Mallo, Ángel Martín-Domenech, Ignacio Rodríguez-Crespo, Nazario Martín
Non-viral nucleic acid vectors able to display high transfection efficiencies with low toxicity and overcoming the multiple biological barriers are needed to further develop the clinical applications of gene therapy.
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Progress in biomimetic leverages for marine antifouling using nanocomposite coatings

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2020, 8,3701-3732
DOI: 10.1039/C9TB02119A, Review Article
Mohamed S. Selim, Sherif A. El-Safty, Mohamed A. Shenashen, Shimaa A. Higazy, Ahmed Elmarakbi
Because of the environmental and economic casualties of biofouling on maritime navigation, modern studies have been devoted toward formulating advanced nanoscale composites in the controlled development of effective marine antifouling self-cleaning surfaces.
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Recent advances of nanomedicines for liver cancer therapy

By pubs.rsc.org
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J. Mater. Chem. B, 2020, 8,3747-3771
DOI: 10.1039/C9TB02871D, Review Article
Xiaoqin Chi, Kun Liu, Xiangjie Luo, Zhenyu Yin, Hongyu Lin, Jinhao Gao
This review highlights recent advancements in nanomedicines for liver cancer therapy.
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Alendronate/folic acid-decorated polymeric nanoparticles for hierarchically targetable chemotherapy against bone metastatic breast cancer

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2020, 8,3789-3800
DOI: 10.1039/D0TB00046A, Paper
Shih-Hong Chen, Te-I Liu, Cheng-Lin Chuang, Hsin-Hung Chen, Wen-Hsuan Chiang, Hsin-Cheng Chiu
Through hierarchically targeting bone matrix and tumor cells, PTX-carrying ALN/FA-nanoparticles substantially accumulate in bone metastases and improve mice survival rate.
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Tumor-mediated shape-transformable nanogels with pH/redox/enzymatic-sensitivity for anticancer therapy

By pubs.rsc.org
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J. Mater. Chem. B, 2020, 8,3801-3813
DOI: 10.1039/D0TB00143K, Paper
Dong Zhou, Sainan Liu, Yongjun Hu, Shiwei Yang, Bing Zhao, Kaikai Zheng, Yuhong Zhang, Peixin He, Guoyan Mo, Yulin Li
Tumor-mediated shape-cleavable nanogels can release drug-carrying ultrasmall nanovesicles through tumor tissue depth, which together with their pH/redox/enzymatic-multistimulative drug release smartness results in a synergistic antitumor efficacy.
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Fluorescence resonance energy transfer-based drug delivery systems for enhanced photodynamic therapy

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J. Mater. Chem. B, 2020, 8,3772-3788
DOI: 10.1039/D0TB00262C, Review Article
Yu Huang, Feng Qiu, Rongjun Chen, Deyue Yan, Xinyuan Zhu
In this Review, recent advances in fluorescence resonance energy transfer-based drug delivery systems for enhanced photodynamic therapy are described, and the current challenges and perspectives in this emerging field are also discussed.
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Nanoclay-functionalized 3D nanofibrous scaffolds promote bone regeneration

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Published On ::

J. Mater. Chem. B, 2020, 8,3842-3851
DOI: 10.1039/C9TB02814E, Paper
Qingqing Yao, Kirby E. Fuglsby, Xiao Zheng, Hongli Sun
A nanoclay-enriched 3D nanofibrous biomimetic scaffold with strong bone regenerative ability by virtue of its improved mechanical properties, osteoconductivity, and drug binding capacity was developed.
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Redox-responsive amphiphilic camptothecin prodrug nanoparticles for targeted liver tumor therapy

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J. Mater. Chem. B, 2020, 8,3918-3928
DOI: 10.1039/D0TB00285B, Paper
Lu Lu, Bing Li, Chuanchuan Lin, Ke Li, Genhua Liu, Zengzilu Xia, Zhong Luo, Kaiyong Cai
A redox-responsive drug carrier with asialoglycoprotein receptor (ASGPR) targeting is fabricated for liver tumor therapy.
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Biodegradable MnFe-hydroxide nanocapsules to enable multi-therapeutics delivery and hypoxia-modulated tumor treatment

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J. Mater. Chem. B, 2020, 8,3929-3938
DOI: 10.1039/D0TB00243G, Paper
Linhua Liao, Dong Cen, Yike Fu, Bin Liu, Chao Fang, Yifan Wang, Xiujun Cai, Xiang Li, Hao Bin Wu, Gaorong Han
Fine nanocapsules based on MnFe hydroxides, showing high loading capacity, O2 induction and biodegradation, were synthesized for effective synergistic therapies.
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A near-infrared light-responsive multifunctional nanocomposite hydrogel for efficient and synergistic antibacterial wound therapy and healing promotion

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J. Mater. Chem. B, 2020, 8,3908-3917
DOI: 10.1039/D0TB00361A, Paper
Na Yang, Ming Zhu, Guochao Xu, Ning Liu, Cong Yu
A multifunctional nanocomposite hydrogel for synergistic antibacterial wound therapy and healing promotion.
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“Watson–Crick GC”-inspired supramolecular nanodrug of methotrexate and 5-fluorouracil for tumor microenvironment-activatable self-recognizing synergistic chemotherapy

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2020, 8,3829-3841
DOI: 10.1039/D0TB00468E, Paper
Meijin Chen, Shiduan Chen, Fukai Zhu, Fanfan Wang, Haina Tian, Zhongxiong Fan, Sunkui Ke, Zhenqing Hou, Yang Li
The “Watson–Crick G≡C”-inspired carrier-free nanodrug have excellent tumor microenvironment-triggered active self-targeting ability and enhanced synergistic chemotherapeutic effects.
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Human serum albumin-based doxorubicin prodrug nanoparticles with tumor pH-responsive aggregation-enhanced retention and reduced cardiotoxicity

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J. Mater. Chem. B, 2020, 8,3939-3948
DOI: 10.1039/D0TB00327A, Paper
Boya Zhang, Shiyu Wan, Xinyu Peng, Mingying Zhao, Sai Li, Yuji Pu, Bin He
A nano-assembly of pH-sensitive doxorubicin prodrug and human serum albumin shows tumor pH-responsive aggregation, enhanced tumor retention and reduced cytotoxicity.
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Synthetic mycomelanin thin films as emergent bio-inspired interfaces controlling the fate of embryonic stem cells

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J. Mater. Chem. B, 2020, Advance Article
DOI: 10.1039/D0TB00623H, Paper
Paola Manini, Valeria Lucci, Valeria Lino, Stefania Sartini, Francesco Rossella, Geppino Falco, Cinzia Chiappe, Marco d’Ischia
Mycomelanin thin films from 1,8-dihydroxynaphthalene can serve as a biointerface inducing adhesion and proliferation of ESCs and promoting their differentiation towards endodermal lineages.
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