This invention relates to the field of biotechnology or genetic engineering. Specifically, this invention relates to the field of gene expression. More specifically, this invention relates to novel substitution mutant receptors and their use in a nuclear receptor-based inducible gene expression system and methods of modulating the expression of a gene in a host cell for applications such as gene therapy, large scale production of proteins and antibodies, cell-based high throughput screening assays, functional genomics and regulation of traits in transgenic organisms.

Provided herein are methods for making water-soluble nanoparticles comprising a core/shell nanocrystal that is coated with a surface layer comprising enough hydrophilic ligands to render the nanoparticle water soluble or water dispersable. Methods for crosslinking molecules on the surface of a nanoparticle, which methods can be used on the above water-soluble nanoparticles also are provided. Nanoparticle compositions resulting from these methods are also provided.

Disclosed are process for contacting a protein containing material with one or more wet-mill streams. The protein content of the protein containing material is increased.

The invention relates to malodor controlling bacteria and related methods and compositions for the control and prevention of malodor.

The present invention relates, in general, to gene expression and, in particular, to a method of inhibiting the expression of a target gene and to constructs suitable for use in such a method.

[Problem to be Solved] The importance of sugar chains having α2,3- or α2,6-linked sialic acid at their non-reducing ends is known. Industrial production has been demanded for these sugar chain compounds. Particularly, the production of glycoprotein drugs or the like inevitably requires producing in quantity sugar chains having homogeneous structures by controlling the linking pattern (α2,6-linkage or α2,3-linkage) of sialic acid. Particularly, a triantennary or tetraantennary N-type complex sugar chain having sialic acid at each of all non-reducing ends is generally considered difficult to chemically synthesize. There has been no report disclosing that such a sugar chain was chemically synthesized. Furthermore, these sugar chains are also difficult to efficiently prepare enzymatically.[Solution]The present inventors have newly found the activity of sialyltransferase of degrading sialic acid on a reaction product in the presence of CMP and also found that formed CMP can be degraded enzymatically to thereby efficiently produce a sialic acid-containing sugar chain. The present inventors have further found that even a tetraantennary N-type sugar chain having four α2,6-linked sialic acid molecules, which has previously been difficult to synthesize, can be prepared at high yields by one-pot synthesis comprising the elongation reaction of a biantennary sugar chain used as a starting material without performing purification after each enzymatic reaction.

A chair assembly includes a four-bar linkage assembly including a first linkage member, a second linkage member, a third linkage member and a fourth linkage member each pivotably coupled to one another such that the four-bar linkage assembly includes an upper end that is adjustable between raised and lowered positions, and an arm rest assembly adapted to support the arm of a seated user thereon and supported the upper end of the four-bar linkage assembly, wherein a lower end of the four-bar linkage assembly is pivotably supported from an arm support structure for pivotable movement, such that the upper end of the four-bar linkage assembly is moveable between a first position and second position located laterally outward from the first position.

A vehicle seat can include a seat bottom frame having a front, a back opposite the front, and enclosing a volume. Pivotally connected to the back of the seat bottom frame can be a seat back frame and pivotally connected to the front of the seat bottom frame can be a seat leg rest. The seat leg rest has a length. Mounted in the volume of the seat frame are at least two leg rest springs which are connected to the leg rest. When the leg rest springs are actuated, the seat leg rest can be directly pivoted approximately and incrementally parallel with the seat bottom frame. The two leg rest springs are mounted a first distance apart and the first distance is less than half of the length of the leg rest.

A stylish ready-to-assemble chaise lounge and sofa which may be easily and quickly assembled by a consumer, is provided. The invention is a kit from which either a stylish chaise lounge or a sofa may be easily assembled by a consumer using a single Allen wrench. The kits, both chaise and sofa, comprise a seat base, a long side seatback and a short side seatback, feet, fasteners and cushions. With regard to the chaise, the long and short side chaise seatbacks have rectangular lower portions with upper portions featuring a flowing curved “waterfall” seating surface which improves the comfort of a user leaning back against the seatback.

The present invention provides a vehicle seat which includes a seat frame, a seat cushion receiving member stretched across the seat frame, and a seat cushion placed on the seat cushion receiving member. In the vehicle seat, the seat cushion has such dimensions as to cover the seat frame as viewed in plan, and a lower surface of the seat cushion has a raised portion in a region covering the seat frame, and the raised portion is raised so as not to contact the seat frame.

A method for enhancing sales of stadium seat memorabilia by utilizing a stabilizing base, with a large surface area in the shape of sports memorabilia, such as baseball bats and/or sports figures, with or without brackets, to mount and stabilize a stadium seat for use outside of the stadium, such as at home or in a commercial setting.

A safety bow assembly for a child seat comprises: a bow body that has opposite first and second ends; first and second connecting parts that are connected to the child seat, the first connecting part defining an accommodating space and having a side wall; and an engaging lever that is connected movably to the side wall, that is formed with an engaging element facing the accommodating space, and that is movable relative to the side wall between a first position, in which the engaging element is adapted to engage releasably a coupling part of the child seat, and a second position, in which the engaging element is adapted to be disengaged from the coupling part.

A vehicle seat has a longitudinal adjuster, a pair of seat rails, a releasable latching device having at least one actuating pin that projects over the second seat rail, a pivotably arranged actuating lever, and a Bowden cable. A holder is fixed on a rail and supports the actuating lever such as to be pivotable about a pivot axis at one end, and a contact surface is formed on the actuating lever, on which surface the core of the Bowden cable rests in a subarea between the end of the sheath and the end of the core. The holder secures the end of the core of the Bowden cable, and the actuating lever has a Bowden cable support on which the sheath of the Bowden cable is supported directly or indirectly.

A folding chair capable of being moved between a folded position and an unfolded position, includes: two units, each of which includes first and second tubes hinged together via a hinge pin; and a canvas sheet, where each assembly of two tubes includes a rigid part at the hinge pin thereof, said rigid part being arranged between two tubes and having: a groove for receiving a tube of the assembly without any degree of freedom; first and second cradles arranged on either side of the hinge pin, such that when the chair is in the unfolded position, the first cradle bears against the upper section of the other tube and the second cradle bears against the lower section of the other tube.

A chair including a dynamically-flexible back and seat having a shape that adjusts to the movements of a user seated in the chair to enhance user comfort. Each of the back and seat has an air gap formed therewithin and a resilient frame or liner with a spring memory. The resilient liner is adapted to flex in response to compressive forces that are generated as the user slides his body back or from side-to-side in the chair. Accordingly, some of the chair back and some of the chair seat move into respective air gaps so that the shapes of the back and seat change to conform to the movements of the user. The air gaps also establish air flow ventilation channels which run laterally through the back and seat of the chair.

A premium class passenger suite that includes a main seat positioned in the suite together with separate bed. The bed has a flexible mattress of predetermined dimensions and is movable between a stowed position to one side of the main seat and a deployed position above and separate from the main seat. A drive apparatus is provided for driving the bed between the stowed and deployed positions. The main seat is configured to be movable between a seating position when the bed is stowed, and a stowed position with a lowered seat back when the bed is deployed for use.

A chair for facilitating efficient stacking includes a seat element having a seat frame, a plurality of front legs attached to a front portion of the seat element, a plurality of rear legs attached to a back portion of the seat element, and one or more telescopic leg mechanisms disposed on at least one of the front or rear legs, wherein the telescopic leg mechanisms provide for lateral movement of the at least one of the front or rear legs with respect to the seat element.

An infant rocking seat includes a base; a track provided on the base having a first arc-shaped portion and a second arc-shaped portion meeting at a crest; a carriage having a body portion, a first pair of wheels positioned at a first end of the body portion, and a second pair of wheels positioned at a second end of the body portion; and a drive mechanism configured to move the carriage along the track. The carriage is positioned within a central portion of the base and is configured to ride along the track. A distance between the first pair of wheels and the second pair of wheels is less than a distance between centers of curvature of the first arc-shaped portion and the second arc-shaped portion.

An ergonomic back support device utilizing one or multiple vertical components that include layers (28,36), pressure distributing layers (34,38,50), and a single notched layer (48). These layers provide primary back support located behind and conforming to the Erector spinae muscles (124). The vertical components form an open channel (24) that is parallel to the prime neurological pathway of the spinal column (100). The vertical conforming support components and open channel facilitate physiological functions that promote health. The device accomplishes support without using any transverse, hard or continuous components across or against the back. Other embodiments include the following additional vertical components: a lateral pressure-adjusting device (14), heating layers (40,46), circulation stimulating layers (42,44), and massage layers (52,54). Embodiments include portable and permanently installed versions that can be utilized in the following applications, including, but not limited to, furniture, vehicles, trains, aircraft, boats, ships, and backpacks.

A child chair apparatus includes a supporting device and a seat device. The seat device is disposed on the supporting device. The seat device includes a fixing component and a seat component. The fixing component is disposed on the supporting device. The fixing component includes a first shaft and a second shaft. The seat component includes an oscillating base and an adjusting base. The oscillating base and the adjusting base are slidably connected to the first shaft and the second shaft respectively, such that the seat component is slidably disposed on the fixing component. The child chair apparatus of the present invention can be switched between the high chair and rocking chair, and has advantages of easy operation and convenient usage.

A fitting for a vehicle seat is disclosed, in particular for a motor vehicle seat. First and second fitting parts are geared with one another via a meshing gearwheel and gear rim. A peripheral eccentric is driven by a drive element for driving a relative rolling movement of the gearwheel and the gear rim, and the first fitting part receives the eccentric which is supported on the second fitting part. A blocking element blocks the eccentric in the non-driven state of the fitting via toothing on the first fitting part, and releases the eccentric when driven. The gear rim is formed on the first fitting part and the gearwheel is formed on the second fitting part.

In a fitting for a vehicle seat, a catch assembly has a pivot axis, and the catch assembly has a catch and a lever which can be pivoted relative to one another about an axis spaced from the pivot axis. The catch has a hook-like contour and in the pivoted-out position of the backrest engages with a catch locking element for locking in a punctiform or linear contact region. The catch cooperates with a spring. The lever is mounted pivotably about the pivot axis and the lever rotatably mounts the catch. In the unloaded pivoted-out position, the perpendicular in the contact region runs on one side of the pivot axis or through the pivot axis. When a return pivoting force is imposed on the backrest in the pivoted-out position, the perpendicular in the contact region runs on the opposing side of or outside of the pivot axis.

A seat cushion, in particular for an aircraft seat, the seat cushion comprising a seat part having a receiving surface adapted to receive a person and a reinforcing part supporting the seat part, wherein at least the reinforcing part contains expanded polypropylene (EPP), preferably comprising fire retardant properties. The invention further relates to a method for manufacturing such a seat cushion, a seat comprising such a seat cushion and a vehicle comprising such a seat.

A chair has a seat support (101), a seat portion (13), a back portion (15), and a supporting frame. The supporting frame is formed by a castored base (11), a height adjustment mechanism (17), and a main transom (21). The seat portion (13) is selectively moveable relative to the supporting frame, with the seat portion having a locked configuration and a released configuration. The back portion has a back frame (25) and a compliant cover (61). The back frame has hook features for receiving a portion of the compliant cover (61). The back portion (15) is reclinable relative to the supporting frame between an upright position and a reclined position. A recline mechanism has deformable members operatively connecting the seat portion and the supporting frame. A recline resistance mechanism is selectively engageable to resist movement of the back portion toward the reclined position.

One lower end portion of a belt anchor bracket is supported on a lock unit rotatably in a front-rear direction, the other lower end portion of the belt anchor bracket is fixed to a leg, and a seatbelt anchor is supported on an upper end portion of the belt anchor bracket rotatably in the front-rear direction.

An operating unit (1) for installation in an aircraft cabin comprises an operating unit front side (10) and an operating unit rear side (20), at least one operating element (12, 14) attached in the region of the operating unit front side (10) and accessible to a user, and a holding device (40) for attaching the operating unit (1) to a monument (30) accommodating the operating unit (1) in its state mounted in the aircraft cabin. The holding device (40) is designed to attach the operating unit (1) in its state mounted in the aircraft cabin to the monument (30), in a first position or in a second position, as desired, the operating element (12, 14) in the second position of the operating unit (1) being situated in a spatial position which is lowered with respect to the spatial position of the operating element (12, 14) in the first position of the operating unit (1) and/or is displaced in a direction parallel to an imaginary straight line connecting the operating unit rear side (20) to the operating unit front side (10).

A method of making a vehicle seat assembly comprising providing a cushion having an “A” surface, a “B” surface, a central portion, and two bolster areas, with each bolster area being adjacent the central portion, the cushion having a plurality of intrusions extending from the “A” surface towards the “B” surface to form a hardness gradient between at least one of the bolster areas and the central portion of between 8% to 25%, securing the cushion to a frame, and covering cushion with a trim member.

A chair assembly for selectively charging an electronic device includes a frame. A back portion of the frame is operationally coupled to a front portion of the frame. A supporting panel is coupled to the frame. The supporting panel may support a user. A leg is coupled to the frame. The leg abuts a support surface so the leg supports the frame above the support surface. An arm rest is operationally coupled to the frame. The arm rest may support the user's arm. A bag is coupled to the arm rest. The bag may contain the electronic device. A charger is operationally coupled to the arm rest. The charger is selectively operationally coupled to the electronic device. The charger may charge the electronic device.

A seating unit that includes a linkage mechanism adapted to move the seating unit between seat-lift, closed, extended, reclined, and seat-lift positions is provided. The linkage mechanism includes a seat-mounting plate mounted to a footrest assembly, a base plate fixedly mounted to a lift assembly, a back-mounting link rotatably coupled to the seat-mounting plate, a seat-adjustment assembly with a bellcrank, and a linear actuator for automating adjustment of the linkage mechanism. In operation, a stroke in a first phase of the linear actuator generates a force on the bellcrank that translates the seat-mounting plate rearward in a consistent angle of inclination and rotates the back-mounting link from a reclined to an upright orientation. A stroke in a second phase acts to collapse the footrest assembly. A stroke in a third phase causes the lift assembly to raise and tilt the seating unit, thereby accommodating egress and ingress of an occupant.

A wire harness for a vehicle seating assembly includes a body portion having a plurality of engagement hooks adapted for engagement with a vehicle seat cushion pan. A latticework of interconnected lateral support members are bound by a peripheral frame.

A bicycle saddle comprising: a supporting frame (2), set up for connecting the saddle to a seat post; a resting base (3), connected to the supporting frame (2) and intended for transmitting the weight of the cyclist to the supporting frame (2), which is provided with a front portion (31) and with a rear portion (32); a cover (4) that covers the resting base (3) and is intended for defining the surface of contact with the cyclist; a shock-absorbing anti-sliding insert (5), interposed between the resting base (3) and the cover (4), which protrudes at least partially from the cover (4) through an opening (41) made on the cover (4).

More specifically, the crash indication system for a child safety seat includes a seat bottom. A base is provided for supporting the seat bottom, which is slidably connected to the bases so that the seat body is movable relative to the base, between a resting position and a ride down position, a position due to a change in environmental forces. The seat body is adjustably affixed to a carriage to set a recline position. An indicator member is attached to the carriage and moves therewith to visually track and monitor the movement of the seat. When ride down of the seat occurs due to a change in forces to the seat, the indicator member moves with the sliding carriage to reflect a ride down position of the seat bottom. A ratchet connection is provided to prevent the carriage from going back to its resting position.

A vehicle seating assembly includes a seatpan coupled with a track assembly that has a rail and a slide. The vehicle seating assembly also includes a cushion assembly that has a movable cushion and a base cushion with a slot. The movable cushion is slidable between a forward position and a rearward position on the seatpan. In addition, the vehicle seating assembly includes a coverstock with a first portion that is disposed over a movable cushion. The coverstock also has a second portion that is disposed between the seatpan and the cushion assembly. The second portion of the coverstock is withdrawn through the slot when the movable cushion moves to the forward position. A gap is defined by the area between the base cushion and the movable cushion in the forward position. The gap is concealed by the coverstock when the movable cushion is in the forward position.

A vehicle seat includes a seat back, a seat cushion, a connecting arm that connects the seat back with the seat cushion, a seat arranging mechanism for changing the posture of the vehicle seat, and a fixing device. The seat arranging mechanism includes a base member at which the seat arranging mechanism is mounted to the connecting arm. The fixing device fixes the connecting arm to the seat cushion and also fixes the base member of the seat arranging mechanism to the seat cushion.

A chair capable of allowing positions of armrests and a back plate to be simultaneously adjusted having an integrated back plate cell including a backrest portion and armrest portions extending forward from the backrest portion, a lower frame including a seat plat support portion and an armrest support portion which extends upward from the seat plat support portion and is coupled to each of the armrest portions, and a fixing lever which fixes the armrest portion to the armrest support portion, wherein the integrated back plate cell is obliquely movable relative to the lower frame.

With a fitting for a vehicle seat, in particular for a motor vehicle seat, having a first fitting part and a second fitting part, which are rotatable relative to one another and are in geared connection with each other, an enclosing ring, which axially holds together the first fitting part and the second fitting part, forming a disc-shaped unit, and which is fixed to the first fitting part and engages over the second fitting part radially outside, and a third fitting part which is pivotably mounted relative to the first fitting part and which can be locked by means of a toothed pawl with a latching element which is provided on the first fitting part, the toothed latching element is formed on the first fitting part.

A latch plate for a lock device is proposed which comprises a latch plate proper and a film that covers the latch plate proper. The latch plate proper includes upper and lower finger portions between which a striker catching recess is defined. An upper surface of the lower finger portion includes a depressed main portion located near the bottom of the striker catching recess, a raised leading end portion and a stepped portion provided between the depressed main portion and the raised leading end portion. The film covers the latch plate proper except the raised leading end portion. The film covers the depressed main portion of the upper surface in such a manner that an outer surface of the film is flush with the stepped portion. When the film is depressed by the striker, the stepped portion enhances a function is to stop a movement of the striker toward a mouth of the striker catching recess.

A mechanism for vertically adjusting a component on a shaft has a collet sleeve riding on the shaft. A spiral track of the component's hub receives a radially outwardly projecting pin on the collet sleeve. The outer surface of the collet sleeve and the inner surface of the hub are tapered so that the hub can rotated one direction to advance the hub on the collet sleeve and compress the collet sleeve onto the shaft to frictionally lock the collet sleeve to the shaft. Because the hub is joined to the collet sleeve by the pin, this also locks the vertical position of the component. Conversely, the hub can be oppositely rotated to release the compression of the collet sleeve so that the collet sleeve, and therefore the vertical component, is slidable on the shaft.

A composite chair includes a chair frame and a fastening assembly. The chair frame includes a front support portion, a rear support portion and two support seat tubes connecting the front support portion to the rear support portion. The rear support portion includes a holding portion and two locking holes. Each support seat tube has a first opening and a second opening faced the fastening hole. The fastening assembly includes two fastening elements inserted in the first openings, a support bar connected to the two fastening elements and two fasteners run through the locking holes and the second openings to fasten to the fastening elements. Each of the fastening elements includes a butting portion and a screw hole. Each of the fasteners includes a thread portion fastened to the screw hole and a detent block butting the holding portion. The composite chair thus formed can be assembled easily.

The present disclosure describes a method of manufacture and a structure for an automobile seat cover that includes a seat cover body with an outer perimeter, a seat cover skirt with a first edge sewn with an overlock stitch to the seat cover body for a majority of the outer perimeter, and a second edge, distal from the first edge, comprising a tie element extending for a majority of the second edge around a seat opening in the seat cover. A portion of the seat cover skirt and the seat cover body corresponding to a location of at least one airbag installed in an automobile seat cover over which the seat cover is to be placed are sewn together with one of a straight stitch and a lock stitch instead of the overlock stitch. In some implementations, the thread used is a brightly colored string.

Embodiments of the present invention include a vehicle seat having a frame member and a reinforcing member for reinforcing the frame member. The frame member has an elongated portion. The elongated portion is formed of resin and preferably has a flat-plate-like or bar-like configuration. The elongated portion includes a first portion, a front second portion and a rear second portion. The first portion may be arranged in a longitudinal manner with respect to the vehicle seat and extends vertically. The front second portion extends in the lateral direction of the vehicle seat from a front end of the first portion. The rear second portion extends in the lateral direction of the vehicle seat from a rear end of the first portion. The elongated portion is configured so that a neutral axis is positioned between the front and rear second portions.

A seat back frame includes: a first side member and a second side member each formed into an elongated shape along an up-and-down direction of a seat back so as to support each side portion of the seat back; and a belt guide portion on which tension of a seat belt is applied when the seat belt is pulled, the belt guide portion being formed in an upper portion of the first side member and guiding the seat belt having the one end retained by a seat belt retaining member. The first side member is formed of a sheet of steel plate and includes: a side member side wall portion formed in parallel to a direction of application of the tension of the seat belt on the belt guide portion and formed continuously along a longitudinal direction of the first side member; a side member front wall portion formed on a front side of the vehicle with respect to the side member side wall portion; and a side member rear wall portion formed on a rear side of the vehicle with respect to the side member side wall portion, the first side member having an open cross-sectional shape.

A cushion element for a vehicle seat or headrest comprises a non-woven layer and a fiber composite material. An insert material is arranged between the non-woven layer and the fiber composite material, and has different compression properties than the fiber composite material. The fiber composite material forms together with the insert material and the non-woven layer a one-piece material composite.

A vehicle seat includes a seat cushion, a seat back connected to the seat cushion and including a storage portion, a belt member configured to restrain an occupant while the belt member is routed from a side of the seat back to a side of the seat cushion, and a rerouter member configured to be taken out from the storage portion of the seat back and connected to the belt member to change a routing position of the belt member at a middle portion thereof. In a state where a portion of the rerouter member is stored in the storage portion, another portion of the rerouter member is exposed from the storage portion.

A vehicle seat comprises: left and right side frames (4) which constitute left and right portions of a seat back frame (2); a reinforcing frame (pipe frame 5) disposed adjacent to one side frame (4) in a lateral direction, and configured to reinforce the side frame (4); and a force-receiving member (bracket 7) disposed adjacent to the one side frame (4), provided discretely from the reinforcing frame, and configured to receive a load from another member. The force-receiving member is disposed opposite to the reinforcing frame with the side frame 4 disposed therebetween, and directly fixed to the reinforcing frame.

A resistance having a high impedance is connected between anode terminals of two variable capacitance diodes sharing a cathode, and the components described above are sealed in one package. The resistance can be formed of a diffusion region between p-regions of the variable capacitance diodes or can be formed of polysilicon and disposed on a chip. Thus, the resistance can be mounted while a chip size of the variable capacitance diode is maintained. Accordingly, it is not required that a bias resistance having a high impedance is additionally provided, whereby achieving reduction in the substrate mounting area and reduction in costs of the set.

An integrated tuner circuit has an arbitrary IF (intermediate frequency) output. The tuner includes an integrated circuit with a fixed-frequency control loop and a matched external variable capacitance Ct, to achieve tracking of a tuned LC band-pass filter with an arbitrary oscillator.

According to an example embodiment, an apparatus is provided that produces a small-step switchable capacitor, which can have steps that are smaller in value than the smallest capacitor used in the system. In one embodiment, an input signal is connected to a switchable capacitor system that includes at least one and/or a plurality of small-step, switchable capacitors. In an example embodiment, a capacitor system may be provided that includes a first capacitance block coupled in series with a second capacitance block. In an example embodiment, the second capacitance block may include one or more switchable capacitors to provide a step in capacitance for the capacitor system between a first setting and a second setting using the one or more switchable capacitors. Also, in an example embodiment, the step in capacitance of the capacitor system may be determined based, at least in part, on a ratio of the capacitance of the second capacitance block to the capacitance of the first capacitance block.

The present invention provides an apparatus for enhancing Q factor of an inductor. The apparatus includes a negative resistance generator coupled to the inductor for providing a negative resistance, and a bias circuit coupled to the negative resistance generator for biasing the negative resistance generator.

The invention provides a variable tuning circuit capable of extending a variable range in a high frequency band, ensuring the value of L of an inductor to increase the value of Q of a circuit in a low frequency band, and preventing a reduction in gain, an increase in noise, and unstable oscillation. A variable tuning circuit includes: a first parallel resonance circuit that includes a varactor diode, a capacitor connected in series to the varactor diode, and a first inductor connected in parallel to the varactor diode and the capacitor; and a second parallel resonance circuit that includes a second inductor connected in parallel to the varactor diode with a direct current cut-off capacitor interposed therebetween. When the varactor diode has a maximum capacitance, a resonant frequency of the second parallel resonance circuit is set about a lowest frequency in a variable frequency range.