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Covid-19 Factoid: India's recovery rate improves to 30% from 10% in April

By www.business-standard.com
Published On :: Sat, 09 May 2020 07:30:00 +0530

But news from Russia and Belgium is worrisome - while the former has seen an unprecedented surge in new cases, the latter's death rate has been rising rapidly


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World coronavirus dispatch: How the wealth management industry is changing

By www.business-standard.com
Published On :: Sat, 09 May 2020 07:34:00 +0530

From US-China talks to end trade deadlock, to FDA nod for Moderna drug's Phase-II trials, and an Amsterdam restaurant with 'quarantine greenhouses' - read these and more in today's world dispatch


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India coronavirus dispatch: Should healthcare be a fundamental right?

By www.business-standard.com
Published On :: Sat, 09 May 2020 07:37:00 +0530

From the role of civil society in times of crises, to returning to the office, and why Bengaluru's migrant construction workers are marching home - read these and more in today's India dispatch


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Vande Bharat: Repatriation flights, ships bring over 700 Indians back home

By www.business-standard.com
Published On :: Sat, 09 May 2020 09:00:00 +0530

Through Vande Bharat Mission, 64 flights and three Navy ships are to repatriate nearly 15,000 Indians stranded abroad


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Opposition leaders write to Prez expressing concern over workers' lives

By www.business-standard.com
Published On :: Sat, 09 May 2020 10:24:00 +0530

In their letter to the President, the Opposition leaders raised the issue of labour laws being nullified and hard-won democratic rights of a vast majority of Indian people people being compromised


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Coronavirus LIVE: Testing scaled up to 95,000 per day, says Harsh Vardhan

By www.business-standard.com
Published On :: Sat, 09 May 2020 10:39:00 +0530

Coronavirus India update: Stay tuned with Business Standard for latest news on COVID-19, world death toll, and cases across the world and in India


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Porters at Jabalpur station face financial stress amid Covid-19 lockdown

By www.business-standard.com
Published On :: Sat, 09 May 2020 11:02:00 +0530

Porters have been dependent on Ticket Collectors for their survival, as any aid from the government is yet to reach them


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Work on to neutralise remaining Styrene gas at LG Polymers' Vizag plant

By www.business-standard.com
Published On :: Sat, 09 May 2020 11:36:00 +0530

The Chief Secretary said the gas leak resulted in 12 deaths, while 454 others had to be admitted to various hospitals


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OCI card holders' entry in India to remain suspended during lockdown: Govt

By www.business-standard.com
Published On :: Sat, 09 May 2020 11:39:00 +0530

The government has kept in abeyance multiple-entry life-long visas given to OCI card holders till the time international travel resumes


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Lockdown 3.0: Odisha ups working hours to 12; staff to be paid for overtime

By www.business-standard.com
Published On :: Sat, 09 May 2020 11:48:00 +0530

No female workers should be allowed or required to work in a factory between 7 pm and 6 am, unless specifically permitted by the government in this regard, the state govt order said


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Govt issues fresh guidelines for discharge of coronavirus patients

By www.business-standard.com
Published On :: Sat, 09 May 2020 12:25:00 +0530

The ministry circular states there will be no coronavirus testing at Covid-19 facilities prior to discharge, and the patients will be advised to follow home isolation for seven days


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Karnataka govt allows restaurants, bars to sell liquor at retail prices

By www.business-standard.com
Published On :: Sat, 09 May 2020 12:39:00 +0530

According to the latest update by the state health department, total number of coronavirus cases in Karnataka is 753


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Aurangabad train accident: Raised an alarm but to no avail, says eyewitness

By www.business-standard.com
Published On :: Sat, 09 May 2020 12:40:00 +0530

As many as 16 migrant labourers were killed and five others injured when a freight train ran over them between Jalna and Aurangabad on Friday


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Vande Bharat Mission: Indians to arrive from Bangladesh, Gulf, UK today

By www.business-standard.com
Published On :: Sat, 09 May 2020 12:51:00 +0530

India had on Monday announced it would begin a phased repatriation of its citizens stranded abroad starting May 7


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Covid-19 hinterland digest: Kanpur means business, Jaipur crime rate drops

By www.business-standard.com
Published On :: Sat, 09 May 2020 17:05:00 +0530

Only half of the transport office will be allowed to open with 33 per cent of the staff


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Microfabricated electrochemical sensing devices

By feeds.rsc.org
Published On ::

Lab Chip, 2020, 20,1358-1389
DOI: 10.1039/C9LC01112A, Critical Review
Fumihiro Sassa, Gokul Chandra Biswas, Hiroaki Suzuki
Electrochemistry provides possibilities to realize smart microdevices of the next generation with high functionalities.
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Optically-controlled closable microvalves for polymeric centrifugal microfluidic devices

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Published On ::

Lab Chip, 2020, 20,1426-1440
DOI: 10.1039/C9LC01187K, Paper
M. Shane Woolf, Leah M. Dignan, Hannah M. Lewis, Christopher J. Tomley, Aeren Q. Nauman, James P. Landers
Microvalving is a pivotal component in many microfluidic lab-on-a-chip platforms and micro-total analysis systems (μTAS).
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Colorimetric absorbance mapping and quantitation on paper-based analytical devices

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Published On ::

Lab Chip, 2020, 20,1441-1448
DOI: 10.1039/D0LC00028K, Paper
Open Access
Yoshiki Soda, Kye J. Robinson, Thomas J. Cherubini, Eric Bakker
A pixel-level colorimetric absorbance analysis can measure the total quantity of dye on paper, irrespective of shape and size.
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Advanced 96-microtiter plate based bioelectrochemical platform reveals molecular short cut of electron flow in cytochrome P450 enzyme

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Published On ::

Lab Chip, 2020, 20,1449-1460
DOI: 10.1039/C9LC01220F, Paper
Ronny Frank, Christoph Prönnecke, Ronny Azendorf, Heinz-Georg Jahnke, Annette G. Beck-Sickinger, Andrea A. Robitzki
We developed a novel 96-well microtiter plate based bioelectrochemical platform with a vertical divided cell three-electrode architecture and a 96-multipotentiostat to perform fully parallelised bioelectrocatalytic screenings on redox enzymes.
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An implantable multifunctional neural microprobe for simultaneous multi-analyte sensing and chemical delivery

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Published On ::

Lab Chip, 2020, 20,1390-1397
DOI: 10.1039/D0LC00021C, Communication
Bo Wang, Ximiao Wen, Yan Cao, Shan Huang, Hoa A. Lam, Tingyi “Leo” Liu, Pei-Shan Chung, Harold G. Monbouquette, Pei-Yu Chiou, Nigel T. Maidment
PDMS thin-film transfer and enzyme microstamping enabled 3-in-1 Si/PDMS hybrid chemtrode for multi-analyte sensing and chemical delivery in vivo.
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Droplet encapsulation improves accuracy of immune cell cytokine capture assays

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Published On ::

Lab Chip, 2020, 20,1513-1520
DOI: 10.1039/C9LC01261C, Paper
Yuan Yuan, Julie Brouchon, J. Mauricio Calvo-Calle, Jing Xia, Li Sun, Xu Zhang, Kiera L. Clayton, Fangfu Ye, David A. Weitz, John A. Heyman
In-droplet cytokine capture assays combined with FACS to accurately identify and isolate activated immune cells.
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Monitoring tissue-level remodelling during inflammatory arthritis using a three-dimensional synovium-on-a-chip with non-invasive light scattering biosensing

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Published On ::

Lab Chip, 2020, 20,1461-1471
DOI: 10.1039/C9LC01097A, Paper
Open Access
Mario Rothbauer, Gregor Höll, Christoph Eilenberger, Sebastian R. A. Kratz, Bilal Farooq, Patrick Schuller, Isabel Olmos Calvo, Ruth A. Byrne, Brigitte Meyer, Birgit Niederreiter, Seta Küpcü, Florian Sevelda, Johannes Holinka, Oliver Hayden, Sandro F. Tedde, Hans P. Kiener, Peter Ertl
We demonstrate that the integration of complex human synovial organ cultures in a lab-on-a-chip provides reproducible and reliable information on how systemic stress factors affect synovial tissue architectures using light scatter biosensing.
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Rapid lipolytic oscillations in ex vivo adipose tissue explants revealed through microfluidic droplet sampling at high temporal resolution

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Published On ::

Lab Chip, 2020, 20,1503-1512
DOI: 10.1039/D0LC00103A, Paper
Juan Hu, Xiangpeng Li, Robert L. Judd, Christopher J. Easley
High temporal resolution sampling and quantitative detection of glycerol secretion dynamics from adipose tissue using our automated, droplet-based microfluidic system.
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Mathematical modeling and computational analysis of centrifugal microfluidic platforms: a review

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Published On ::

Lab Chip, 2020, 20,1318-1357
DOI: 10.1039/C9LC00775J, Critical Review
Open Access
Masoud Madadelahi, Luis F. Acosta-Soto, Samira Hosseini, Sergio O. Martinez-Chapa, Marc J. Madou
This paper focuses on theory and computational modelling of lab-on-a-disc devices of relevance for novel applications discovery and optimal designs.
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Fluorescence-based sorting of Caenorhabditis elegans via acoustofluidics

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Published On ::

Lab Chip, 2020, Advance Article
DOI: 10.1039/D0LC00051E, Paper
Jinxin Zhang, Jessica H. Hartman, Chuyi Chen, Shujie Yang, Qi Li, Zhenhua Tian, Po-Hsun Huang, Lin Wang, Joel N. Meyer, Tony Jun Huang
Acoustofluidic sorting of Caenorhabditis elegans in a high throughput manner.
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ECM-based microchannel for culturing in vitro vascular tissues with simultaneous perfusion and stretch

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Published On ::

Lab Chip, 2020, Advance Article
DOI: 10.1039/D0LC00254B, Paper
Azusa Shimizu, Wei Huang Goh, Shun Itai, Michinao Hashimoto, Shigenori Miura, Hiroaki Onoe
A perfusable and stretchable gelatin-based microfluidic system that can apply both simultaneous fluidic shear stress and stretch stress to in vitro endothelial 3D tissues is presented.
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Development of two-photon polymerised scaffolds for optical interrogation and neurite guidance of human iPSC-derived cortical neuronal networks

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Published On ::

Lab Chip, 2020, Advance Article
DOI: 10.1039/C9LC01209E, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
J. A. Crowe, A. El-Tamer, D. Nagel, A. V. Koroleva, J. Madrid-Wolff, O. E. Olarte, S. Sokolovsky, E. Estevez-Priego, A.-A. Ludl, J. Soriano, P. Loza-Alvarez, B. N. Chichkov, E. J. Hill, H. R. Parri, E. U. Rafailov
We identified photopolymers for 2-photon polymerisation with biocompatibility for human iPSC-derived neural network development. Generation of microscale scaffold topologies enabled neurite guidance, demonstrating use in reproducing aligned networks.
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Development and characterisation of acoustofluidic devices using detachable electrodes made from PCB

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Published On ::

Lab Chip, 2020, Advance Article
DOI: 10.1039/C9LC01192G, Paper
Roman Mikhaylov, Fangda Wu, Hanlin Wang, Aled Clayton, Chao Sun, Zhihua Xie, Dongfang Liang, Yinhua Dong, Fan Yuan, Despina Moschou, Zhenlin Wu, Ming Hong Shen, Jian Yang, Yongqing Fu, Zhiyong Yang, Christian Burton, Rachel J. Errington, Marie Wiltshire, Xin Yang
We demonstrate a novel SAW device fabrication technique by mechanically clamping interdigital electrodes (IDEs) on the printed circuit board (PCB) to a LiNbO3 wafer. The novel PCB-SAW device is capable of performing all the functions of standard SAW devices.
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SLOCK (sensor for circadian clock): passive sweat-based chronobiology tracker

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Published On ::

Lab Chip, 2020, Advance Article
DOI: 10.1039/D0LC00134A, Paper
Sayali Upasham, Shalini Prasad
SLOCK is a sweat based platform for monitoring circadian relevant biomarkers-cortisol and DHEA, using electrochemical detection modality.
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A new microfluidic model that allows monitoring of complex vascular structures and cell interactions in a 3D biological matrix

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Published On ::

Lab Chip, 2020, Advance Article
DOI: 10.1039/D0LC00059K, Paper
Open Access
Christian G. M. van Dijk, Maarten M. Brandt, Nikolaos Poulis, Jonas Anten, Matthijs van der Moolen, Liana Kramer, Erik F. G. A. Homburg, Laura Louzao-Martinez, Jiayi Pei, Merle M. Krebber, Bas W. M. van Balkom, Petra de Graaf, Dirk J. Duncker, Marianne C. Verhaar, Regina Luttge, Caroline Cheng
We present a microfluidic vascular device. Vascular cells in a 3D-ECM environment support hemodynamic flow and enable monocyte interaction.
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Microfluidic device for high-throughput affinity-based isolation of extracellular vesicles

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Published On ::

Lab Chip, 2020, Advance Article
DOI: 10.1039/C9LC01190K, Paper
Ting-Wen Lo, Ziwen Zhu, Emma Purcell, Daniel Watza, Joyful Wang, Yoon-Tae Kang, Shruti Jolly, Deepak Nagrath, Sunitha Nagrath
Immunoaffinity based EV isolation technologies use antibodies targeting surface markers on EVs to provide higher isolation specificity and purity compared to existing approaches.
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Direct loading of blood for plasma separation and diagnostic assays on a digital microfluidic device

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Published On ::

Lab Chip, 2020, Advance Article
DOI: 10.1039/D0LC00302F, Paper
Christopher Dixon, Julian Lamanna, Aaron R. Wheeler
The integration of 3D porous membranes in a digital microfluidic device enables the generation of cell-free plasma from finger-stick volumes of blood with in-line, on-chip analysis.
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In situ generation of plasma-activated aerosols via surface acoustic wave nebulization for portable spray-based surface bacterial inactivation

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Published On ::

Lab Chip, 2020, Advance Article
DOI: 10.1039/D0LC00001A, Paper
Kiing S. Wong, William T. H. Lim, Chien W. Ooi, Leslie Y. Yeo, Ming K. Tan
We demonstrate an efficient technique for in situ production and application of plasma-activated aerosols for surface disinfection.
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A new polymer lab-on-a-chip (LOC) based on a microfluidic capillary flow assay (MCFA) for detecting unbound cortisol in saliva

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Published On ::

Lab Chip, 2020, Advance Article
DOI: 10.1039/D0LC00071J, Paper
Vinitha T. U., Sthitodhi Ghosh, Alexander Milleman, Thinh Nguyen, Chong H. Ahn
A new polymer lab-on-a-chip with on-chip dried reagents for microfluidic capillary flow assay (MCFA) detection of unbound cortisol in saliva.
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Spatially isolated reactions in a complex array: using magnetic beads to purify and quantify nucleic acids with digital and quantitative real-time PCR in thousands of parallel microwells

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Published On ::

Lab Chip, 2020, Advance Article
DOI: 10.1039/D0LC00069H, Paper
W. Hampton Henley, Nathan A. Siegfried, J. Michael Ramsey
Encoded beads carrying primer pairs for nucleic acid targets are used for sample preparation and multiplexed-in-space digital PCR quantification.
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Open sessile droplet viscometer with low sample consumption

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Published On ::

Lab Chip, 2020, Advance Article
DOI: 10.1039/D0LC00248H, Paper
Matthias Hermann, Kyle Bachus, Graham T. T. Gibson, Richard D. Oleschuk
This paper reports a portable viscometer that requires less than 10 μL of sample for a measurement.
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In-air EIS sensor for in situ and real-time monitoring of in vitro epithelial cells under air-exposure

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Published On ::

Lab Chip, 2020, Advance Article
DOI: 10.1039/C9LC01064E, Paper
Seungbeom Noh, Hanseup Kim
This paper reports in-air monitoring of in vitro monolayer cells under air-exposure utilizing electrochemical impedance spectroscopy (EIS).
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Clip-to-release on amplification (CRoA): a novel DNA amplification enhancer on and off microfluidics

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Published On ::

Lab Chip, 2020, Advance Article
DOI: 10.1039/D0LC00318B, Paper
Ren Shen, Yanwei Jia, Pui-In Mak, Rui P. Martins
A proposed DNA amplification enhancer with a “clip-to-release on amplification” mechanism reduces dye-mediated inhibition to amplification, increases fluorescence signal up to 10-fold, and eliminates false-negative results for on-chip PCR.
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Acoustic separation of living and dead cells using high density medium

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Published On ::

Lab Chip, 2020, Advance Article
DOI: 10.1039/D0LC00175A, Paper
Open Access
Karl Olofsson, Björn Hammarström, Martin Wiklund
A novel, simple and robust route for binary separation of viable and dead cells using a density modified medium which takes advantage of the compromised cell membrane of dead cells.
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Bioinspired reconfiguration of 3D printed microfluidic hydrogels via automated manipulation of magnetic inks

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Published On ::

Lab Chip, 2020, Advance Article
DOI: 10.1039/D0LC00280A, Communication
Amin Mansoorifar, Anthony Tahayeri, Luiz E. Bertassoni
We proposed a novel concept for reconfiguration of hydrogel microfluidic devices, where multiple fluidic pathways could be generated via reversible manipulation of magnetic inks.
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Capacitive Sensing of Triglyceride Film Reactions: A Proof-of-Concept Demonstration for Sensing in Simulated Duodenal Contents with Gastrointestinal Targeting Capsule System

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Published On ::

Lab Chip, 2020, Accepted Manuscript
DOI: 10.1039/D0LC00133C, Paper
George Banis, Luke Beardslee, Justin Stine, Rajendra Mayavan Sathyam, Reza Ghodssi
Ingestible capsule systems continue evolving to overcome drawbacks associated with traditional gastrointestinal (GI) diagnostic and therapeutic processes, such as location restrictions or insufficient sensitivity measures when obtaining information on local...
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PRESCIENT: platform for the rapid evaluation of antibody success using integrated microfluidics enabled technology

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Published On ::

Lab Chip, 2020, 20,1628-1638
DOI: 10.1039/C9LC01165J, Paper
Jose A. Wippold, Han Wang, Joseph Tingling, Julian L. Leibowitz, Paul de Figueiredo, Arum Han
Identifying antibodies (Abs) that neutralize infectious agents is the first step for developing therapeutics, vaccines, and diagnostic tools for these infectious agents.
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Auto-affitech: an automated ligand binding affinity evaluation platform using digital microfluidics with a bidirectional magnetic separation method

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Published On ::

Lab Chip, 2020, 20,1577-1585
DOI: 10.1039/D0LC00024H, Paper
Jingjing Guo, Li Lin, Kaifeng Zhao, Yanling Song, Mengjiao Huang, Zhi Zhu, Leiji Zhou, Chaoyong Yang
An automated ligand binding affinity evaluation platform using digital microfluidics with a bidirectional magnetic separation method that reduces the bead loss.
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Microfluidic device to study flow-free chemotaxis of swimming cells

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Published On ::

Lab Chip, 2020, 20,1639-1647
DOI: 10.1039/D0LC00045K, Paper
Nicolas Garcia-Seyda, Laurene Aoun, Victoria Tishkova, Valentine Seveau, Martine Biarnes-Pelicot, Marc Bajénoff, Marie-Pierre Valignat, Olivier Theodoly
Permeable agarose barriers allow flow-free gradient generation, applicable to adherent and non-adherent (swimming) cells, as well as co-culture experiments.
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Quantitatively controllable fluid flows with ballpoint-pen-printed patterns for programmable photo-paper-based microfluidic devices

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Published On ::

Lab Chip, 2020, 20,1601-1611
DOI: 10.1039/D0LC00115E, Paper
Veasna Soum, Sooyong Park, Albertus Ivan Brilian, Jae-Youl Choi, Yongwoo Lee, Wonjung Kim, Oh-Sun Kwon, Kwanwoo Shin
A precise, simple, and inexpensive method for controlling fluid flow in a photo-paper-based microfluidic device was reported.
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Monitoring the two-dimensional concentration profile of toluene vapors by using polymer-stabilized nematic liquid crystals in microchannels

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Published On ::

Lab Chip, 2020, 20,1687-1693
DOI: 10.1039/C9LC01021A, Paper
Zongdai Liu, Dan Luo, Kun-Lin Yang
The concentration of toluene vapor is obtained based on polymer-stabilized liquid crystals by viewing a colourful gamut under a polarized optical microscope.
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Electrostatically gated nanofluidic membrane for ultra-low power controlled drug delivery

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Published On ::

Lab Chip, 2020, 20,1562-1576
DOI: 10.1039/D0LC00121J, Paper
Open Access
Nicola Di Trani, Antonia Silvestri, Antons Sizovs, Yu Wang, Donald R. Erm, Danilo Demarchi, Xuewu Liu, Alessandro Grattoni
Control of molecular diffusion through nanofluidic channels using electrostatic gating.
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Hybrid paper and 3D-printed microfluidic device for electrochemical detection of Ag nanoparticle labels

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Published On ::

Lab Chip, 2020, 20,1648-1657
DOI: 10.1039/D0LC00276C, Paper
Charuksha Walgama, Michael P. Nguyen, Lisa M. Boatner, Ian Richards, Richard M. Crooks
A hybrid paper/plastic microfluidic device for detection of Ag nanoparticle labels at concentrations as low as 12 pM.
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Selective cell propagation via micropatterning of a thermally-activated hydrogel

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Published On ::

Lab Chip, 2020, 20,1544-1553
DOI: 10.1039/C9LC01230C, Communication
Jeffrey C. Y. Chiu, Joyce A. Teodoro, Jeong Hyun Lee, Kerryn Matthews, Simon P. Duffy, Hongshen Ma
Inverse gelation of methylcellulose enables hydrogel micropatterning to selectively propagate cells identified by microscopy.
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Matrix density drives 3D organotypic lymphatic vessel activation in a microfluidic model of the breast tumor microenvironment

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Published On ::

Lab Chip, 2020, 20,1586-1600
DOI: 10.1039/D0LC00099J, Paper
Karina M. Lugo-Cintrón, José M. Ayuso, Bridget R. White, Paul M. Harari, Suzanne M. Ponik, David J. Beebe, Max M. Gong, María Virumbrales-Muñoz
Lymphatic organotypic in vitro model allows the examination of components of the tumor microenvironment (e.g., ECM density, cancer cells) in lymphatic vessel biology in the context of cancer, providing insights into potential therapeutic targets.
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