com Cannibalism helps comb jellies survive harsh conditions, invade new environs By www.upi.com Published On :: Fri, 08 May 2020 14:57:57 -0400 The warty comb jelly is native to the western Atlantic, but in recent decades, it has invaded the waters of Eurasia. New research suggests cannibalism is key to the species' ability to move into new environs. Full Article
com Migration & Coronavirus: A Complicated Nexus Between Migration Management and Public Health By www.migrationpolicy.org Published On :: Thu, 19 Mar 2020 10:35:46 -0400 This webinar, organized by MPI and the Zolberg Institute on Migration and Mobility at The New School, discussed the state of play around the globe surrounding COVID-19 and examined where migration management and enforcement tools may be useful and where they may be ill-suited to advancing public health goals. Full Article
com Side-by-Side Comparison of 2013 Senate Immigration Bill with 2006 and 2007 Senate Legislation By www.migrationpolicy.org Published On :: Mon, 01 Apr 2013 00:00:00 -0400 This fact sheet compares key components of immigration reform outlined in the 2013 Senate immigration bill against provisions included in bills considered by the Senate in 2006 and 2007: border security, detention, and enforcement; worksite enforcement; visa reforms; earned legalization of unauthorized immigrants; strengthening the U.S. economy and workforce; and integration of new Americans. Full Article
com Side-by-Side Comparison of the 2013 Senate Immigration Framework with 2006 and 2007 Senate Legislation By www.migrationpolicy.org Published On :: Mon, 01 Apr 2013 00:00:00 -0400 MPI has completed an analysis of the major provisions in the 2013 framework, comparing them to provisions of the legislation the Senate considered in 2006 and 2007. This fact sheet is formatted as a chart comparing the framework of comprehensive immigration reform outlined in the 2013 Senate immigration bill against provisions included in bills considered by the Senate in 2006 and 2007. Full Article
com Side-by-Side Comparison of 2013 Senate Immigration Bill with Individual 2013 House Bills By www.migrationpolicy.org Published On :: Thu, 01 Aug 2013 00:00:00 -0400 This fact sheet offers a detailed review of the comprehensive immigration reform legislation approved by the U.S. Senate in June 2013 and compares its major provisions with those of the five targeted immigration bills approved by the House Judiciary Committee and the House Homeland Security Committee. Full Article
com Ask Ariely: On Irrational Investments and Company Complaints By danariely.com Published On :: Sat, 18 Jan 2020 12:30:17 +0000 Here’s my Q&A column from the WSJ this week — and if you have any questions for me, you can tweet them to @danariely with the hashtag #askariely, post a comment on my Ask Ariely Facebook page, or email them to AskAriely@wsj.com. ___________________________________________________ Dear Dan, One of my credit cards bears... Full Article Ask Ariely Behavioral Economics Blog advice column ask ariely Behavioral Economics & Psychology dear dan wall street journal wsj
com Watch: Pete Davidson says Bill Hader recommended him for 'SNL' By www.upi.com Published On :: Fri, 08 May 2020 09:59:32 -0400 Pete Davidson discussed on "The Tonight Show" how Bill Hader helped him land a spot on "Saturday Night Live." Full Article
com 'Community' cast reuniting for COVID-19 benefit live read By www.upi.com Published On :: Fri, 08 May 2020 13:13:20 -0400 "Community" creator Dan Harmon and cast members Joel McHale, Donald Glover, Alison Brie, Yvette Nicole Brown, Gillian Jacobs, Danny Pudi, Jim Rash and Ken Jeong will perform a table read and Q&A for charity. Full Article
com Sarah Silverman, Seth Rogen animated series coming to HBO Max By www.upi.com Published On :: Fri, 08 May 2020 15:41:35 -0400 HBO Max announced Friday that it has ordered "Santa Inc.," an adult-oriented animated series featuring the voices of Sarah Silverman and Seth Rogen. Full Article
com Entertainer Roy Horn of Siegfried & Roy dies of COVID-19 complications at 75 By www.upi.com Published On :: Sat, 09 May 2020 08:39:06 -0400 German-born entertainer Roy Uwe Ludwig Horn, one half of the stage duo Siegfried & Roy, has died of complications from the coronavirus. He was 75. Full Article
com Improving Communication with Your Partner During COVID-19 Quarantine By psychcentral.com Published On :: Sun, 03 May 2020 20:30:40 +0000 Best-selling author Harville Hendrix weighs in on improving your relationships while in quarantine. Relationships are one of life’s most beautiful offerings. What may feel like a gift on some days... Full Article Publishers Relationships YourTango Communication coronavirus COVID-19 pandemic Partner quarantine
com [ Dogs ] Open Question : I've come to a conclusion,Dogs section on YA is not worth my time or energy, it is bad enough it is full of what I assume are teenagers? By answers.yahoo.com Published On :: Sat, 09 May 2020 17:14:50 +0000 playing games but now I am being repeatedly harassed and accused of being a troll named Sophie. Well you all can just keep this grimy pool. I am not wasting my time or energy. Enjoy yourselves. Full Article
com [ Investing ] Open Question : What does an investor do when his stock notifies him...the company confirms a record date for a forward two for one stock split? By answers.yahoo.com Published On :: Sat, 09 May 2020 17:16:31 +0000 Full Article
com [ United States ] Open Question : Is my $1,200 stimulus check taxable as income? By answers.yahoo.com Published On :: Sat, 09 May 2020 17:18:26 +0000 Full Article
com [ Politics ] Open Question : Is it true many British and American banks and companies(Bank of England,UIC,Prescott Bush,etc) gave money and goods to Hitler secretly? By answers.yahoo.com Published On :: Sat, 09 May 2020 17:24:02 +0000 Full Article
com [ Religion & Spirituality ] Open Question : How come there are different writers attributed to the Gospel of Mark.... why would Mark need different people to write his Gospel.? By answers.yahoo.com Published On :: Sat, 09 May 2020 17:24:57 +0000 Full Article
com Sweden: By Turns Welcoming and Restrictive in its Immigration Policy By www.migrationpolicy.org Published On :: Wed, 05 Dec 2018 18:28:24 -0500 Swedish asylum policy has taken a restrictionist turn since the country received a record-breaking number of asylum seekers in 2015 and after electoral gains by the nationalist, anti-immigration Sweden Democrats pushed the governing coalition to a harder line. Still, other aspects of the country’s migration policy remain welcoming, as this country profile explores. Full Article
com Should You Immerse Yourself in Bad News These Days or Ignore It Completely? By rss.sciam.com Published On :: Tue, 05 May 2020 11:00:00 GMT Neither approach is ideal. The best option is to temper your negative emotions by focusing on positive ones -- Read more on ScientificAmerican.com Full Article Mind Behavior & Society
com Flamingos Can Be Picky about Company By rss.sciam.com Published On :: Fri, 08 May 2020 00:58:00 GMT They don’t stand on one leg around just anybody but often prefer certain members of the flock. -- Read more on ScientificAmerican.com Full Article Mind Behavior & Society Conservation The Sciences Evolution
com The Insurgency's Psychological Component By www.washingtonpost.com Published On :: Mon, 03 Sep 2007 00:00:00 EDT At the core of this fall's debate over Iraq lies one simple question: Can an increased number of U.S. troops subdue the Iraqi insurgency? Full Article Opinions The Insurgency's Psychological Component
com With Power Comes a Selfish Point of View By www.washingtonpost.com Published On :: Mon, 26 Nov 2007 00:00:00 EST In the interest of promoting democracy, Pakistan's president, Gen. Pervez Musharraf, recently announced that he had to lock up most of his country's democracy activists. And because he wanted the Pakistani Supreme Court to independently rule on whether he could continue as president, Musharraf also... Full Article Opinions With Power Comes a Selfish Point of View
com The Science of Presidential Complexity By www.washingtonpost.com Published On :: Mon, 28 Jan 2008 00:00:00 EST Mitt Romney wants to round up 12 million illegal immigrants and deport them. John Edwards wants to put an end to lobbyists. All the Democratic and Republican presidential candidates rail against the ways of Washington. Full Article Opinions The Science of Presidential Complexity
com For Political Candidates, Saying Can Become Believing By www.washingtonpost.com Published On :: Mon, 25 Feb 2008 00:00:00 EST John McCain once called televangelists Pat Robertson and Jerry Falwell "agents of intolerance," but now the Republican senator from Arizona is currying favor with social conservatives. Sen. Hillary Rodham Clinton (D-N.Y.) now opposes the Iraq war, although she used to support it. Sen. Barack Obama... Full Article Opinions For Political Candidates Saying Can Become Believing
com When Play Becomes Work By www.washingtonpost.com Published On :: Mon, 28 Jul 2008 00:00:00 EDT It happens all the time: Two guys in a garage come up with a cool new technology -- and dream of making it big. A thousand people take time off work to campaign for a visionary politician because they feel they are doing something to change the world. A million kids hit baseballs -- and wonder what... Full Article Opinions When Play Becomes Work
com The Computer as a Road Map to Unknowable Territory By www.washingtonpost.com Published On :: Mon, 16 Feb 2009 00:00:00 EST Last year, as the financial meltdown was getting underway, a scientist named Yaneer Bar-Yam developed a computer model of the economy. Instead of the individuals, companies and brokers that populate the real economy, the model used virtual actors. The computer world allowed Bar-Yam to do what... Full Article Opinions The Computer as a Road Map to Unknowable Territory
com Engaging Communities in Refugee Protection: The Potential of Private Sponsorship in Europe By www.migrationpolicy.org Published On :: Wed, 06 Sep 2017 17:20:24 -0400 Across Europe, grassroots efforts have emerged in the wake of crisis that draw members of the public into the process of receiving refugees and supporting their integration. This policy brief examines the many forms community-based or private sponsorship can take, what benefits such approaches may hold for European communities, and the tradeoffs policymakers face in their implementation. Full Article
com Cracked Foundation, Uncertain Future: Structural Weaknesses in the Common European Asylum System By www.migrationpolicy.org Published On :: Fri, 16 Mar 2018 18:13:48 -0400 During the 2015–16 migration crisis, European asylum systems were stretched to a breaking point. Yet many of the structural issues that contributed to failures to register newcomers, insufficient reception capacity, and growing backlogs of asylum cases existed before—and many remain unresolved. This report critically evaluates Common European Asylum System legal and operational shortcomings at a time when reform is on the table. Full Article
com Two- and three-color STORM analysis reveals higher-order assembly of leukotriene synthetic complexes on the nuclear envelope of murine neutrophils [Computational Biology] By www.jbc.org Published On :: 2020-04-24T06:08:45-07:00 Over the last several years it has become clear that higher order assemblies on membranes, exemplified by signalosomes, are a paradigm for the regulation of many membrane signaling processes. We have recently combined two-color direct stochastic optical reconstruction microscopy (dSTORM) with the (Clus-DoC) algorithm that combines cluster detection and colocalization analysis to observe the organization of 5-lipoxygenase (5-LO) and 5-lipoxygenase–activating protein (FLAP) into higher order assemblies on the nuclear envelope of mast cells; these assemblies were linked to leukotriene (LT) C4 production. In this study we investigated whether higher order assemblies of 5-LO and FLAP included cytosolic phospholipase A2 (cPLA2) and were linked to LTB4 production in murine neutrophils. Using two- and three-color dSTORM supported by fluorescence lifetime imaging microscopy we identified higher order assemblies containing 40 molecules (median) (IQR: 23, 87) of 5-LO, and 53 molecules (62, 156) of FLAP monomer. 98 (18, 154) molecules of cPLA2 were clustered with 5-LO, and 77 (33, 114) molecules of cPLA2 were associated with FLAP. These assemblies were tightly linked to LTB4 formation. The activation-dependent close associations of cPLA2, FLAP, and 5-LO in higher order assemblies on the nuclear envelope support a model in which arachidonic acid is generated by cPLA2 in apposition to FLAP, facilitating its transfer to 5-LO to initiate LT synthesis. Full Article
com Specificity and affinity of the N-terminal residues in staphylocoagulase in binding to prothrombin [Computational Biology] By www.jbc.org Published On :: 2020-04-24T06:08:45-07:00 In Staphylococcus aureus–caused endocarditis, the pathogen secretes staphylocoagulase (SC), thereby activating human prothrombin (ProT) and evading immune clearance. A previous structural comparison of the SC(1–325) fragment bound to thrombin and its inactive precursor prethrombin 2 has indicated that SC activates ProT by inserting its N-terminal dipeptide Ile1-Val2 into the ProT Ile16 pocket, forming a salt bridge with ProT's Asp194, thereby stabilizing the active conformation. We hypothesized that these N-terminal SC residues modulate ProT binding and activation. Here, we generated labeled SC(1–246) as a probe for competitively defining the affinities of N-terminal SC(1–246) variants preselected by modeling. Using ProT(R155Q,R271Q,R284Q) (ProTQQQ), a variant refractory to prothrombinase- or thrombin-mediated cleavage, we observed variant affinities between ∼1 and 650 nm and activation potencies ranging from 1.8-fold that of WT SC(1–246) to complete loss of function. Substrate binding to ProTQQQ caused allosteric tightening of the affinity of most SC(1–246) variants, consistent with zymogen activation through occupation of the specificity pocket. Conservative changes at positions 1 and 2 were well-tolerated, with Val1-Val2, Ile1-Ala2, and Leu1-Val2 variants exhibiting ProTQQQ affinity and activation potency comparable with WT SC(1–246). Weaker binding variants typically had reduced activation rates, although at near-saturating ProTQQQ levels, several variants exhibited limiting rates similar to or higher than that of WT SC(1–246). The Ile16 pocket in ProTQQQ appears to favor nonpolar, nonaromatic residues at SC positions 1 and 2. Our results suggest that SC variants other than WT Ile1-Val2-Thr3 might emerge with similar ProT-activating efficiency. Full Article
com What Should Successful Integration Look Like for Vulnerable Newcomers? By www.migrationpolicy.org Published On :: Wed, 08 Jan 2020 09:26:09 -0500 WASHINGTON — As host countries in Europe, North America and beyond prioritize getting refugees and other newly arrived migrants into work, another challenge has received less attention: Helping those who may never find jobs participate meaningfully in their new communities. Newcomers who are not in the workplace (particularly refugee women, migrants who are unskilled or illiterate and the elderly) are at high risk for social isolation. Full Article
com As Brussels seeks fresh ideas to reform the Common European Asylum System, innovative member state responses offer a wealth of lessons–and some caution By www.migrationpolicy.org Published On :: Wed, 04 Mar 2020 17:03:43 -0500 Brussels and Gütersloh, 05.03.2020 — Anticipated reform of the Common European Asylum System (CEAS), which was high on the agenda as nearly 2 million asylum seekers arrived at Europe’s door in 2015-16, quickly fell victim to EU Member State competing views on what constitutes equal burden-sharing, domestic politics around migration and the urgency of first addressing overtaxed national asylum systems. Full Article
com Beyond Work: Reducing Social Isolation for Refugee Women and Other Marginalized Newcomers By www.migrationpolicy.org Published On :: Fri, 03 Jan 2020 16:41:08 -0500 As migrant- and refugee-receiving countries in Europe, North America, and beyond prioritize services that are focused on employment, language instruction, and civic integration, newcomers who are not in the workplace are at high risk for social isolation. As a result, societies should reconsider what successful integration looks like for vulnerable newcomers who will never find traditional employment or who need a longer-than-average timeline to get there. Full Article
com Rebuilding Community after Crisis: Striking a New Social Contract for Diverse Societies (Transatlantic Council Statement) By www.migrationpolicy.org Published On :: Tue, 14 Jan 2020 09:52:21 -0500 Addressing the deep-rooted integration challenges unearthed by large-scale migration and rapid social change will require a combination of strategies. Governments in Europe and North America must create a new social contract for increasingly diverse societies that are confronting cycles of disruption. This report sketches a blueprint for an adaptive process oriented by skill needs rather than national origins. Full Article
com chocolate mousse with honeycomb and espresso sauce By www.abc.net.au Published On :: Tue, 25 Oct 2016 11:09:00 +1100 honeycomb 40 g (11/2 oz) honey 70 g (21/2 oz) glucose syrup 200 g (7 oz) caster (superfine) sugar 1 teaspoon bicarbonate of soda (baking soda), sifted mousse 200 g (7 oz/11/3 cups) chopped good-quality dark chocolate, such as couverture (see note, page 235) 40 g (11/2 oz) unsalted butter, chopped 4 eggs, separated 150 g (51/2 oz/2/3 heaped cup) sugar espresso sauce 250 ml (9 fl oz/1 cup) espresso coffee 100 g (31/2 oz/1/2 cup) sugar 2 tablespoons kahlua Full Article ABC Local northcoast Lifestyle and Leisure:Food and Cooking:All Lifestyle and Leisure:Recipes:All Lifestyle and Leisure:Recipes:Main Australia:NSW:Lismore 2480
com Welcome Wears Thin for Colombians in Ecuador as Venezuelans Become More Visible By www.migrationpolicy.org Published On :: Wed, 08 Jan 2020 19:31:49 -0500 Though Colombians displaced by a decades-long civil war found a welcome refuge in Ecuador, life has become more difficult for them in recent years, in part as a result of the influx of Venezuelans seeking safety. This article draws on surveys of migrants in Quito, comparing and contrasting the experiences of Colombians and Venezuelans, and assessing their perceptions of discrimination, victimization, trust in institutions, and hopes for the future. Full Article
com An Uneven Welcome: Latin American and Caribbean Responses to Venezuelan and Nicaraguan Migration By www.migrationpolicy.org Published On :: Mon, 03 Feb 2020 17:19:48 -0500 Large-scale displacement from Venezuela and Nicaragua is reshaping the migration landscape in much of Latin America and the Caribbean. This report, accompanied by the launch of a new Migration Portal offering research and analysis on the region, examines the immigration and integration policy responses of 11 countries, including pathways to legal status and measures to integrate newcomers into schools, health-care systems, and labor markets. Full Article
com Microvascular and Cardiovascular Outcomes According to Renal Function in Patients Treated With Once-Weekly Exenatide: Insights From the EXSCEL Trial By care.diabetesjournals.org Published On :: 2020-01-20T12:00:30-08:00 OBJECTIVE To evaluate the impact of once-weekly exenatide (EQW) on microvascular and cardiovascular (CV) outcomes by baseline renal function in the Exenatide Study of Cardiovascular Event Lowering (EXSCEL). RESEARCH DESIGN AND METHODS Least squares mean difference (LSMD) in estimated glomerular filtration rate (eGFR) from baseline between the EQW and placebo groups was calculated for 13,844 participants. Cox regression models were used to estimate effects by group on incident macroalbuminuria, retinopathy, and major adverse CV events (MACE). Interval-censored time-to-event models estimated effects on renal composite 1 (40% eGFR decline, renal replacement, or renal death) and renal composite 2 (composite 1 variables plus macroalbuminuria). RESULTS EQW did not change eGFR significantly (LSMD 0.21 mL/min/1.73 m2 [95% CI –0.27 to 0.70]). Macroalbuminuria occurred in 2.2% of patients in the EQW group and in 2.5% of those in the placebo group (hazard ratio [HR] 0.87 [95% CI 0.70–1.07]). Neither renal composite was reduced with EQW in unadjusted analyses, but renal composite 2 was reduced after adjustment (HR 0.85 [95% CI 0.74–0.98]). Retinopathy rates did not differ by treatment group or in the HbA1c-lowering or prior retinopathy subgroups. CV outcomes in those with eGFR <60 mL/min/1.73 m2 did not differ by group. Those with eGFR ≥60 mL/min/1.73 m2 had nominal risk reductions for MACE, all-cause mortality, and CV death, but interactions by renal function group were significant for only stroke (HR 0.74 [95% CI 0.58–0.93]; P for interaction = 0.035) and CV death (HR 1.08 [95% CI 0.85–1.38]; P for interaction = 0.031). CONCLUSIONS EQW had no impact on unadjusted retinopathy or renal outcomes. CV risk was modestly reduced only in those with eGFR ≥60 mL/min/1.73 m2 in analyses unadjusted for multiplicity. Full Article
com Visit-to-Visit HbA1c Variability Is Associated With Cardiovascular Disease and Microvascular Complications in Patients With Newly Diagnosed Type 2 Diabetes By care.diabetesjournals.org Published On :: 2020-01-20T12:00:30-08:00 OBJECTIVE To investigate the association between visit-to-visit HbA1c variability and cardiovascular events and microvascular complications in patients with newly diagnosed type 2 diabetes. RESEARCH DESIGN AND METHODS This retrospective cohort study analyzed patients from Tayside and Fife in the Scottish Care Information–Diabetes Collaboration (SCI-DC) who were observable from the diagnosis of diabetes and had at least five HbA1c measurements before the outcomes were evaluated. We used the previously reported HbA1c variability score (HVS), calculated as the percentage of the number of changes in HbA1c >0.5% (5.5 mmol/mol) among all HbA1c measurements within an individual. The association between HVS and 10 outcomes was assessed using Cox proportional hazards models. RESULTS We included 13,111–19,883 patients in the analyses of each outcome. The patients with HVS >60% were associated with elevated risks of all outcomes compared with the lowest quintile (for example, HVS >80 to ≤100 vs. HVS ≥0 to ≤20, hazard ratio 2.38 [95% CI 1.61–3.53] for major adverse cardiovascular events, 2.4 [1.72–3.33] for all-cause mortality, 2.4 [1.13–5.11] for atherosclerotic cardiovascular death, 2.63 [1.81–3.84] for coronary artery disease, 2.04 [1.12–3.73] for ischemic stroke, 3.23 [1.76–5.93] for heart failure, 7.4 [3.84–14.27] for diabetic retinopathy, 3.07 [2.23–4.22] for diabetic peripheral neuropathy, 5.24 [2.61–10.49] for diabetic foot ulcer, and 3.49 [2.47–4.95] for new-onset chronic kidney disease). Four sensitivity analyses, including adjustment for time-weighted average HbA1c, confirmed the robustness of the results. CONCLUSIONS Our study shows that higher HbA1c variability is associated with increased risks of all-cause mortality, cardiovascular events, and microvascular complications of diabetes independently of high HbA1c. Full Article
com The Prevalence and Determinants of Cognitive Deficits and Traditional Diabetic Complications in the Severely Obese By care.diabetesjournals.org Published On :: 2020-02-20T11:55:30-08:00 OBJECTIVE To determine the prevalence of cognitive deficits and traditional diabetic complications and the association between metabolic factors and these outcomes. RESEARCH DESIGN AND METHODS We performed a cross-sectional study in severely obese individuals before bariatric surgery. Lean control subjects were recruited from a research website. Cognitive deficits were defined by the National Institutes of Health (NIH) Toolbox (<5th percentile for lean control subjects). Cardiovascular autonomic neuropathy (CAN) was defined by an expiration-to-inspiration (E-to-I) ratio of <5th percentile for lean control subjects. Retinopathy was based on retinal photographs and nephropathy on the estimated glomerular filtration rate (<60 mg/dL) and/or the albumin-to-creatinine ratio (ACR) (≥30 mg/g). NIH Toolbox, E-to-I ratio, mean deviation on frequency doubling technology testing, and ACR were used as sensitive measures of these outcomes. We used multivariable linear regression to explore associations between metabolic factors and these outcomes. RESULTS We recruited 138 severely obese individuals and 46 lean control subjects. The prevalence of cognitive deficits, CAN, retinopathy, and nephropathy were 6.5%, 4.4%, 0%, and 6.5% in lean control subjects; 22.2%, 18.2%, 0%, and 6.1% in obese participants with normoglycemia; 17.7%, 21.4%, 1.9%, and 17.9% in obese participants with prediabetes; and 25.6%, 31.9%, 6.1%, and 16.3% in obese participants with diabetes. Waist circumference was significantly associated with cognitive function (–1.48; 95% CI –2.38, –0.57) and E-to-I ratio (–0.007; 95% CI –0.012, –0.002). Prediabetes was significantly associated with retinal function (–1.78; 95% CI –3.56, –0.002). CONCLUSIONS Obesity alone is likely sufficient to cause cognitive deficits but not retinopathy or nephropathy. Central obesity is the key metabolic risk factor. Full Article
com Predicting 10-Year Risk of End-Organ Complications of Type 2 Diabetes With and Without Metabolic Surgery: A Machine Learning Approach By care.diabetesjournals.org Published On :: 2020-03-20T11:50:34-07:00 OBJECTIVE To construct and internally validate prediction models to estimate the risk of long-term end-organ complications and mortality in patients with type 2 diabetes and obesity that can be used to inform treatment decisions for patients and practitioners who are considering metabolic surgery. RESEARCH DESIGN AND METHODS A total of 2,287 patients with type 2 diabetes who underwent metabolic surgery between 1998 and 2017 in the Cleveland Clinic Health System were propensity-matched 1:5 to 11,435 nonsurgical patients with BMI ≥30 kg/m2 and type 2 diabetes who received usual care with follow-up through December 2018. Multivariable time-to-event regression and random forest machine learning models were built and internally validated using fivefold cross-validation to predict the 10-year risk for four outcomes of interest. The prediction models were programmed to construct user-friendly web-based and smartphone applications of Individualized Diabetes Complications (IDC) Risk Scores for clinical use. RESULTS The prediction tools demonstrated the following discrimination ability based on the area under the receiver operating characteristic curve (1 = perfect discrimination and 0.5 = chance) at 10 years in the surgical and nonsurgical groups, respectively: all-cause mortality (0.79 and 0.81), coronary artery events (0.66 and 0.67), heart failure (0.73 and 0.75), and nephropathy (0.73 and 0.76). When a patient’s data are entered into the IDC application, it estimates the individualized 10-year morbidity and mortality risks with and without undergoing metabolic surgery. CONCLUSIONS The IDC Risk Scores can provide personalized evidence-based risk information for patients with type 2 diabetes and obesity about future cardiovascular outcomes and mortality with and without metabolic surgery based on their current status of obesity, diabetes, and related cardiometabolic conditions. Full Article
com Migration & Coronavirus: A Complicated Nexus Between Migration Management and Public Health By www.migrationpolicy.org Published On :: Tue, 24 Mar 2020 15:13:37 -0400 This webinar, organized by MPI and the Zolberg Institute on Migration and Mobility at The New School, discussed migration policy responses around the globe in response to the COVID-19 pandemic, and examined where migration management and enforcement tools may be useful and where they may be ill-suited to advancing public health goals. Full Article
com A Study of Pregnancy and Birth Outcomes among African-Born Women Living in Utah By www.migrationpolicy.org Published On :: Mon, 07 Nov 2016 14:30:31 -0500 Resettled African refugee women may experience particularly acute complications during pregnancy, birth, and the child's early infancy. Yet health care-providers and policymakers may not be aware of the particular challenges that these women and their children face. This report, examining women giving birth in Utah over a seven-year period, compares perinatal complications of the African born and a segment of the U.S. born. Full Article
com Can a Company be pro-regulation and pro-commerce? Gregg Renfrew from Beautycounter thinks so By brandleadership.wordpress.com Published On :: Fri, 19 Feb 2016 18:59:09 +0000 It’s the middle of an election year and, according to the Pew Research Center, the country hasn’t been this polarized since the Civil War. In such a climate, it would seem to be an oxymoron for a company to push for both financial growth and tighter regulations. Gregg Renfrew, CEO & Founder of Beautycounter, wouldn’t […] Full Article *Gabriela Torres Patiño Brand Strategy Business Values Customer Experience Event Marketing
com Musculoskeletal Complications of Diabetes Mellitus By clinical.diabetesjournals.org Published On :: 2001-07-01 Rachel Peterson KimJul 1, 2001; 19:Practical Pointers Full Article
com Effects of Glycemic Control on Diabetes Complications and on the Prevention of Diabetes By clinical.diabetesjournals.org Published On :: 2004-10-01 Jay S. SkylerOct 1, 2004; 22:162-166Feature Articles Full Article
com Integration of Clinical Psychology in the Comprehensive Diabetes Care Team By clinical.diabetesjournals.org Published On :: 2004-07-01 Steven B. LeichterJul 1, 2004; 22:129-131The Business of Diabetes Full Article
com Persistence of Continuous Glucose Monitoring Use in a Community Setting 1 Year After Purchase By clinical.diabetesjournals.org Published On :: 2013-07-01 James ChamberlainJul 1, 2013; 31:106-109Feature Articles Full Article
com Diabetes Self-Management in a Community Health Center: Improving Health Behaviors and Clinical Outcomes for Underserved Patients By clinical.diabetesjournals.org Published On :: 2008-01-01 Daren AndersonJan 1, 2008; 26:22-27Bridges to Excellence Full Article
com Amylin Replacement With Pramlintide in Type 1 and Type 2 Diabetes: A Physiological Approach to Overcome Barriers With Insulin Therapy By clinical.diabetesjournals.org Published On :: 2002-07-01 John B. BuseJul 1, 2002; 20:Feature Articles Full Article
com Microvascular and Macrovascular Complications of Diabetes By clinical.diabetesjournals.org Published On :: 2008-04-01 Michael J. FowlerApr 1, 2008; 26:77-82Diabetes Foundation Full Article