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Infra development critical for growth, achieving $5 trillion economy by FY25: FinMin report

Infra development will especially be critical for the success of the Make in India programme as manufacturing competitiveness critically depends on infrastructure, the final report of the task force submitted to Finance Minister Nirmala Sitharaman said.




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NCLT approves Ebix’s revival plan for Trimax IT Infrastructure

Ebix Software India (ESIPL) will pay upfront Rs 75 crore to acquire the company. The company owed over Rs 1,918 crore to its lenders, including about Rs 1,700 crore to financial creditors.




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Synthesis, evaluation and molecular modelling of piceatannol analogues as arginase inhibitors

RSC Med. Chem., 2020, Advance Article
DOI: 10.1039/D0MD00011F, Research Article
J. Muller, B. Cardey, A. Zedet, C. Desingle, M. Grzybowski, P. Pomper, S. Foley, D. Harakat, C. Ramseyer, C. Girard, M. Pudlo
A quantum chemistry guided optimisation (leading to piceatannol analogue 3t) with a good understanding of the catechol binding mode to the bimanganese cluster of arginase.
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The content of this RSS Feed (c) The Royal Society of Chemistry




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Recent progress on phenotype-based discovery of dengue inhibitors

RSC Med. Chem., 2020, Advance Article
DOI: 10.1039/D0MD00052C, Review Article
Fumiaki Yokokawa
The review presents the discovery of new dengue inhibitors by a phenotype-based approach.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Discovery, SAR study and ADME properties of methyl 4-amino-3-cyano-1-(2-benzyloxyphenyl)-1H-pyrazole-5-carboxylate as an HIV-1 replication inhibitor

RSC Med. Chem., 2020, Advance Article
DOI: 10.1039/D0MD00025F, Research Article
Jeanne Fichez, Cathia Soulie, Laurent Le Corre, Sophie Sayon, Stéphane Priet, Karine Alvarez, Olivier Delelis, Patrick Gizzi, Guillaume Prestat, Christine Gravier-Pelletier, Anne-Geneviève Marcelin, Vincent Calvez, Patricia Busca
Identified as an HIV-1 inhibitor in cellulo, this pyrazole does not belong to the three main classes of anti HIV-drugs, a feature of prime interest in the context of viral resistance.
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Protein—fragment complex structures derived by NMR Molecular Replacement

RSC Med. Chem., 2020, Accepted Manuscript
DOI: 10.1039/D0MD00068J, Research Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Felix Torres, Dhiman Ghosh, Dean Strotz, Celestine Chi, Ben Davis, Julien Orts
Recently we have established an NMR Molecular Replacement method, which is capable of solving the structure of the interaction site of protein-ligand complexes in a fully automated manner. While the...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Cyclic boronates as versatile scaffolds for KPC-2 β-lactamase inhibition

RSC Med. Chem., 2020, 11,491-496
DOI: 10.1039/C9MD00557A, Research Article
Catherine L. Tooke, Philip Hinchliffe, Alen Krajnc, Adrian J. Mulholland, Jürgen Brem, Christopher J. Schofield, James Spencer
Mono- (vaborbactam) and bi-cyclic (taniborbactam) boronate inhibitors bind KPC-2 similarly, but the latter is essentially irreversible.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Vascular tone and angiogenesis modulation by catecholamine coordinated to ruthenium

RSC Med. Chem., 2020, 11,497-510
DOI: 10.1039/C9MD00573K, Research Article
Jacqueline Querino Alves, Laena Pernomian, Cássia Dias Silva, Mayara Santos Gomes, Ana Maria de Oliveira, Roberto Santana da Silva
The interaction of catecholamine site to receptors drives the proangiogenic to antiangiogenic character.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Recent progress in selective estrogen receptor downregulators (SERDs) for the treatment of breast cancer

RSC Med. Chem., 2020, 11,438-454
DOI: 10.1039/C9MD00570F, Review Article
Shagufta, Irshad Ahmad, Shimy Mathew, Sofia Rahman
This article reviews the current progress in the development of SERDs as anti-breast cancer agents.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Reversing binding sensitivity to A147T translocator protein

RSC Med. Chem., 2020, 11,511-517
DOI: 10.1039/C9MD00580C, Research Article
Sophie V. Vo, Samuel D. Banister, Isaac Freelander, Eryn L. Werry, Tristan A. Reekie, Lars M. Ittner, Michael Kassiou
A loss in binding affinity at A147T relative to WT TSPO is seen with most TSPO ligands. Provision of hydrogen-bonding opportunities on indole carboxamides rescues this loss in affinity.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Arylsulfonyl histamine derivatives as powerful and selective α-glucosidase inhibitors

RSC Med. Chem., 2020, 11,518-527
DOI: 10.1039/C9MD00559E, Research Article
M. I. Osella, M. O. Salazar, M. D. Gamarra, D. M. Moreno, F. Lambertucci, D. E. Frances, R. L. E. Furlan
N α,Nτ-Di-4-trifluorobenzenesulfonyl histamine inhibits α-glucosidase in vitro reversibly and selectively with a Ki value of 11.6 μM, and shows an in vivo hypoglycemic effect in mice.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Unveiling the active isomer of cycloalanopine, a cyclic opine from Lactobacillus rhamnosus LS8, through synthesis and analog production

RSC Med. Chem., 2020, 11,528-531
DOI: 10.1039/D0MD00033G, Research Article
Isaac Antwi, Sorina Chiorean, Marco J. van Belkum, John C. Vederas
Stereochemistry of the antimicrobial isomer of a cyclic opine was determined by synthesis using oxidative cyclisation of a bis-hydrazide.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Chemotherapy for human schistosomiasis: how far have we come? What's new? Where do we go from here?

RSC Med. Chem., 2020, 11,455-490
DOI: 10.1039/D0MD00062K, Review Article
Godwin Akpeko Dziwornu, Henrietta Dede Attram, Samuel Gachuhi, Kelly Chibale
After a century since the first antimonial-based drugs were introduced to treat the disease, anti-schistosomiasis drug development is again at a bottleneck with only one drug, praziquantel, available for treatment purposes.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Computer-aided discovery of phenylpyrazole based amides as potent S6K1 inhibitors

RSC Med. Chem., 2020, Advance Article
DOI: 10.1039/C9MD00537D, Research Article
Yan Yin, Yuxing Sun, Lianhua Zhao, Jinpeng Pan, Yangbo Feng
Ribosomal protein S6 kinase beta-1 (S6K1) is an attractive therapeutic target.
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The content of this RSS Feed (c) The Royal Society of Chemistry




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How Silverstone circuit could help F1

Silverstone managing director, Stuart Pringle made clear that everything had to be done so as not to put stress on policing or divert medical resources away from the fight against the coronavirus.




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Albon denies Leclerc a virtual F1 'trick

The Thai's victory over his Ferrari rival gave Red Bull something to celebrate on a day that should have seen the return of Max Verstappen's home Dutch Grand Prix after a 35-year absence.




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F1 teams must race to survive

Formula One managing director Ross Brawn this week outlined plans for going back to racing, with health checks and isolation in the paddock, and believed the sport could provide a safe environment.




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Reducing operational costs in composites manufacturing / by Karen Snyder Travis

Online Resource




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After net neutrality: a new deal for the digital age / Victor Pickard and David Elliot Berman

Dewey Library - HE7645.P535 2019




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Internet of vehicles: technologies and services toward smart cities: 6th International Conference, IOV 2019, Kaohsiung, Taiwan, November 18-21, 2019, Proceedings / Ching-Hsien Hsu, Sondès Kallel, Kun-Chan Lan, Zibin Zheng (eds.)

Online Resource




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Rütteldruckverdichtung als Plastodynamisches Problem: Deep vibration compaction as plastodynamic problem / W. Fellin

Online Resource




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Performance measures in snow and ice control operations / ICF with Athey Creek Consultants and Vaisala Inc

Barker Library - TE7.N275 no.889




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Reinventing business models: how firms cope with disruption / Henk Volberda, Frans van den Bosch, Kevin Heij

Dewey Library - HD30.28.V66 2018




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Hydraulic rubber dam: an effective water management technology / edited by Sabu Thomas, Ajay Vasudeo Rane, Abitha V.K., Krishnan Kanny, Aastha Dutta

Barker Library - TC540.H937 2019




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Belly-rippers, surgical innovation and the ovariotomy controversy / Sally Frampton

Hayden Library - RG481.F73 2018




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Siliciclastic reserviors of the Arabian Plate / Edited by H. R. AlAnzi, R. A. Rahmani, R. J. Steel, O. M. Soliman

Dewey Library - TN876.A1 S55 2019




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Knowledge, power, and women's reproductive health in Japan, 1690-1945 / Yuki Terazawa

Hayden Library - RG67.J3 T44 2018




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Design of concrete bridge beams prestressed with CFRP systems / Abdeldjelil Belardi, Mina Dawood, Prakash Poudel [and five others]

Barker Library - TE7.N275 no.907




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Guide to truck activity data for emissions modeling / Christopher Porter, Timothy Grose, John Koupal, Kanok Boriboonsomsin, George Noel, Andrew Eilbert

Barker Library - TE7.N275 no.909




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Building a multimodal future: connecting real estate development and transportation demand management to ease gridlock / Justin B. Schor, Federico Tallis

Rotch Library - HE308.S36 2019




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Transportation workforce planning and development strategies / Robert Puentes, Alice Grossman, Brianne Eby, Alex Bond

Barker Library - TE7.N2755 no.543




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Global aspects of reputation and strategic management / editied by David L. Deephouse, Naomi A. Gardberg, and William Newburry

Dewey Library - HD30.28.G56 2019




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The vagina bible: the vulva and the vagina - separating the myth from the medicine / Jen Gunter, MD

Barker Library - RG268.G86 2019




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Admissibility and public availability of transit safety planning records / Committee to Review Evidentiary Protection for Public Transporation Safety Program Information, Transportation Research Board

Barker Library - TE7.N2774 no.326




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Managing state transportation research programs: a synthesis of highway practice / Donald Ludlow, Vivek Sakhrani, Camille Wu

Barker Library - TE7.N2755 no.522




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Tools to facilitate implementation of effective metropolitan freight transportation strategies / Bill Eisele [and 8 others]

Barker Library - TE7.N275 no.897




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Reinforced concrete design / Chu-Kia Wang, Charles G.Salmon, José A.Pincheira, Gustavo J.Parra-Montesinos, University of Wisconsin-Madison

Barker Library - TA683.2.W3 2018




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Performance of longitudinal barriers on curved, superelevated roadway sections / Dhafer Marzougui; Cing-Dao "Steve" Kan; Umashankar Mahadevaiah; Fadi Tahan; Christopher Story; Stefano Dolci; Alberto Moreno; Kenneth S. Opiela; Richard Powers

Barker Library - TE7.N275 no.894




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Prioritization of freight investment projects: a synthesis of highway practice / Mario M. Monsreal, Matthew Miller, Madison Metsker-Galarza, Madison Graham, Juan Carlos Villa

Barker Library - TE7.N2755 no.542




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Benchmarking and comparative meeasurement for effective performance management by transportation agencies / Joe Crossett, Anna Batista, Hyun-A Park, Hugh Louch, and Kim Voros

Barker Library - TE7.N275 no.902




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TRANSBALTICA XI: transportation science and technology: proceedings of the International Conference TRANSBALTICA, May 2-3, 2019, Vilnius, Lithuania / edited by Kasthurirangan Gopalakrishnan, Olegas Prentkovskis, Irina Jackiva, Raimundas Junevičius

Online Resource




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Emerging technologies for construction delivery / consultant, John J. Hannon

Barker Library - TE7.N2755 no.534




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Transport in shale reservoirs / Kun Sang Lee, Tae Hong Kim

Barker Library - TN858.L44 2019




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Lives on the line: how the Philippines became the world's call center capital / Jeffrey J. Sallaz

Dewey Library - HE8789.P45 S35 2019




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Organization design / edited by John Joseph (University of California, Irvine, USA), Oliver Baumann (University of Southern Denmark, Denmark), Richard Burton (Duke University, USA), Kannan Srikanth (Ohio State University, USA)

Dewey Library - HD30.28.O72 2019




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Decision-making for sustainable transport and mobility: multi actor multi criteria analysis / edited by Cathy Macharis (Professor, Vrije University Brussel-Research group MOBI (Mobility, Logistics and Automotive Technology), dep. BUTO, Belgium), Gino Baud

Rotch Library - HE305.D36 2018




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LRFD minimum flexural reinforcement requirements / Sri Sritharan, Hartanto Wibowo, Michael J. Rosenthal, Jacob N. Eull (Iowa State University) ; Jay Holombo (T.Y. Lin International)

Barker Library - TE7.N25 no.906




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Quantifying the effects of preservation treatments on pavement performance / Gonzalo R. Rada, James M. Bryce, Beth A. Visintine, R. Gary Hicks, DingXen Cheng

Barker Library - TE7.N275 no.858




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Cambridge handbook of open strategy / edited by David Seidl, Richard Whittington, Georg von Krogh

Dewey Library - HD30.28.C3479 2019




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Workforce optimization workbook for transportation construction projects / Timothy Taylor, Roy Sturgill, Steve Waddle, Ying Li, Kentucky Transportation Center; Paul Goodrum, Keith Molenaar, Sara Al-Haddad, University of Colorado Boulder

Online Resource