Parents normally feel the need to provide well for their kids. For humans, that number of offspring is usually in the single digits, but a […]

The post The secret formula to feeding 900 babies: Scientists uncover milk composition of naked mole-rat queens appeared first on Smithsonian Insider.

The Smithsonian Conservation Biology Institute and the SVF Foundation have launched a new collaboration to strengthen rare and endangered livestock breed conservation through the preservation […]

The post Smithsonian & SVF launch rare-breed livestock conservation partnership appeared first on Smithsonian Insider.

The carabid beetle tribe Lachnophorini is the focus of an extensive new study by two Smithsonian entomologists just published in a special issue of the […]

The post New study focuses on carabid beetles appeared first on Smithsonian Insider.

Today the Smithsonian launches its Transcription Center website to the public. The website is designed to leverage the power of crowds to help the Smithsonian […]

The post Volunteers needed for massive Smithsonian digitization project appeared first on Smithsonian Insider.

Before iPhones and laptops there were human computers, some of whom worked at the Harvard College Observatory. Women like Henrietta Swan Leavitt, Williamina Fleming, and […]

The post Volunteers needed to preserve astronomical history and promote discovery appeared first on Smithsonian Insider.

Human skin and gut microbes influence processes from digestion to disease resistance. Despite the fact that tropical forests are the most biodiverse terrestrial ecosystems on […]

The post Smithsonian scientists discover tropical tree microbiome in Panama appeared first on Smithsonian Insider.

What crunchy food did Americans spend $5.5 billion on last year—with sales that spiked before snow and ice storms? If you guessed birdseed then you […]

The post Simple tips to keep your backyard birds healthy this winter appeared first on Smithsonian Insider.

The rusty-patched bumble bee (Bombus affinis), which has not been seen in the eastern United States in five years, has been found by a Smithsonian […]

The post Rare rusty-patched bumble bee discovered in Virginia survey appeared first on Smithsonian Insider.

You too can meet a kiwi! Micaela Jemison from Smithsonian Science takes us to the Smithsonian’s National Zoo where she gets up close and personal […]

The post Meet a Kiwi at the National Zoo appeared first on Smithsonian Insider.

The majestic feathers of the greater bird of paradise (Paradisaea apoda) have inspired people for thousands of years. Like many birds on the isolated island […]

The post Feathers of seduction – the connection between birds and people of New Guinea appeared first on Smithsonian Insider.

You watch the weather forecast, gear up with hat, coat, scarf and gloves, but you still get cold after just a short time in the […]

The post Keeping Warm in Winter is for the Birds appeared first on Smithsonian Insider.

How soon after the Big Bang could water have existed? Not right away, because water molecules contain oxygen and oxygen had to be formed in […]

The post Water may Have Been Abundant in First Billion Years after big bang appeared first on Smithsonian Insider.

New data just published in the journal Marine Mammal Science may help save the whales, or at least a good many of them. Using vertebrae […]

The post New study may help free whales from fishing rope entanglement appeared first on Smithsonian Insider.

The Inka Empire is one of the greatest civilizations in the Western Hemisphere, spanning from the 13th century until the Spanish invasion in 1532. To […]

The post 5 Reasons the Inka Road is one of the Greatest Achievements in Engineering appeared first on Smithsonian Insider.

Who: Wheelerodemus muhlenbergiae What: A newly discovered species of plant eating bug belonging to the family Blissidae, members of which are found worldwide. W. muhlenbergiae […]

The post Meet a new true bug: “Wheelerodemus muhlenbergiae” appeared first on Smithsonian Insider.

Like other kids at summer camp, a group of youngsters in the cities of Miami, Okla. and Fort Wayne, Ind. play games, work on crafts […]

The post Digitized, Searchable Archives Help Revive ‘Sleeping’ Languages appeared first on Smithsonian Insider.

Surplus mustard gas canisters and unexploded bombs dumped in the Pacific Ocean near Hawaii after WWII, have become, scientists say, a potential reef that is […]

The post Old bombs, chemical weapons now home for deep-sea starfish appeared first on Smithsonian Insider.

Since researchers began surveys in the 1980s, coral reefs in the Caribbean have undergone widespread change following bleaching and disease epidemics that have reduced the […]

The post Study reveals Agriculture and Fishing Cause Coral Reef Decline appeared first on Smithsonian Insider.

We only have one example of a planet with life: Earth. But within the next generation, it should become possible to detect signs of life […]

The post Interstellar Seeds Could Create Oases of Life appeared first on Smithsonian Insider.

Recently crowned the “astronomy photo of the year” by Slate’s Bad Astronomy blog, a new image of a region of Orion’s belt reveals the deepest […]

The post Stunning deep space photo reveals new details of Orion nebulae appeared first on Smithsonian Insider.

New research by a team of archaeologists has revealed a curious connection between our traditional Thanksgiving dinner and the taste buds of prehistoric mammoths and […]

The post Study reveals ancient link between mammoth dung and pumpkin pie appeared first on Smithsonian Insider.

Throughout 2015 the Smithsonian Environmental Research Center (SERC) in Edgewater, Md., has marked its 50th year of operation. Now there’s another reason for SERC to […]

The post Smithsonian lab receives GreenGov Presidential Award appeared first on Smithsonian Insider.

Bei Bei, Bao Bao, Tian Tian. Many people recognize the names of the giant pandas that reside at the Smithsonian’s National Zoo. Yet Juan Rodriguez […]

The post Meet Juan Rodriguez, panda keeper at the National Zoo appeared first on Smithsonian Insider.

Through sheer coincidence, two Smithsonian researchers at the National Zoological Park have discovered that 18 percent of the white-tailed deer population in the Eastern United […]

The post Smithsonian study reveals white-tailed deer in eastern U.S. are infected with a malaria parasite appeared first on Smithsonian Insider.

On September 14, 2015, the Laser Interferometer Gravitational-wave Observatory (LIGO) detected gravitational waves from the merger of two black holes 29 and 36 times the […]

The post Ligo’s Twin Black Holes Might Have Been Born Inside a Single Star appeared first on Smithsonian Insider.

The pink-headed duck was no lucky duck. In 1948 a single specimen of this waterfowl, Rhodonessa caryophyllacea, was donated to the Division of Birds of […]

The post Carotenoid pigments make extinct duck a rare bird indeed appeared first on Smithsonian Insider.

A social media celebrity was born last week when the bright lights and camera of NOAA’s remotely operated vehicle Deep Discoverer zoomed in on a […]

The post Ghost octopod shows how little we know about deep-sea life appeared first on Smithsonian Insider.

New high-speed videos of 14 species of tiny Mecysmaucheniid “trap-jaw” spiders have revealed that some species can snap their mouth parts shut at incredibly fast […]

The post Discovery: trap-jaw spiders snap prey with super-spidey speed and power appeared first on Smithsonian Insider.

Remember the scene in Moonraker where Robert Kiel, as the steel-toothed character Jaws, bites through a tram cable that sends Roger Moore’s James Bond sprawling? […]

The post Smithsonian Discovery: 46-million-year-old beetle had zinc jaws appeared first on Smithsonian Insider.

The planet’s last stronghold of wild cheetahs (Acinonyx jubatus) is losing genetic diversity at an alarming rate according to a new study from the Smithsonian […]

The post Smithsonian Study reveals Decline of Genetic Diversity in Wild Cheetahs appeared first on Smithsonian Insider.

Thanks to a recent reassessment of specimens preserved in jars of alcohol at the Smithsonian’s National Museum of Natural History, New Hampshire is now on […]

The post Discovery in Smithsonian collection broadens understanding of rare North American leech appeared first on Smithsonian Insider.

Meet Scorpaenodes barrybrowni is a scorpionfish species newly discovered by Smithsonian scientists using a manned submersible in the deep-reef waters of the Caribbean island of Curaçao. It […]

The post New bright orange-red scorpionfish discovered deep in Caribbean appeared first on Smithsonian Insider.

With over 138 million collection objects, 2.1 million library volumes, and 137,000 cubic feet of archives, the stories of how our collections have made their […]

The post Seventeen Objects for 170 Years (Happy Birthday to us!) appeared first on Smithsonian Insider.

To surprise their prey, some species of seabirds dive into the water at speeds greater than 50 miles per hour. A human diver entering the […]

The post Study shows how birds dive safely at high speeds appeared first on Smithsonian Insider.

Recent underwater photographs and video from the National Marine Park of the southern Caribbean island of Bonaire has led to the discovery of a new species […]

The post Meet the candy striped hermit crab, a new Caribbean species appeared first on Smithsonian Insider.

Food is scarce in the deep, dark regions of the ocean where barbeled dragonfishes and their relatives dwell. Known as the Stomiidae, some of these […]

The post Odd anatomy: flexible joint between skull and spine allow dragonfish to open wide appeared first on Smithsonian Insider.

To fully know a species and develop sound conservation efforts, its full life cycle must be understood. But tracking small migratory birds for thousands of […]

The post Keeping Track of Kirtland’s Warbler All Year Long―A Scientific First appeared first on Smithsonian Insider.

A bizarre change occurs in the mouth of a humpback whale during its development in the womb. Several dozen tooth buds sprout in a row […]

The post Paleo-detectives energize great whale mystery: how & when baleen evolved appeared first on Smithsonian Insider.

For more than 60 years, researchers have tried to successfully cryopreserve (or freeze) the embryo of zebrafish, a species that is an important medical model […]

The post Gold nanotechnology and lasers used to successfully freeze fish embryos appeared first on Smithsonian Insider.

This animation shows how binary neutron stars warp space-time to create gravitational waves, then collide and explode into a visible kilonova, which can be detected […]

The post Astronomers see light show associated with gravitational waves appeared first on Smithsonian Insider.

A new study from the Smithsonian Conservation Biology Institute (SCBI) is helping make headway in an area of animal management that has historically proven challenging: […]

The post Early indicator of cheetah pregnancy identified appeared first on Smithsonian Insider.

“Somber” is the adjective Smithsonian beetle expert Terry Erwin uses to describe the insects he collects on the forest floor in Peru and Ecuador. “They […]

The post Meet the newest New World canopy beetle species. ‘Gazillions’ await discovery. appeared first on Smithsonian Insider.

Swimming in the frigid waters of the Arctic and surfacing in narrow gaps in the sea ice to breathe, the narwhal is one of the […]

The post Meet the world’s weirdest whale appeared first on Smithsonian Insider.

Animal species can become endangered, but what about languages? Around 80 percent of the world’s population speaks just 20 percent of its 7,000 languages. That […]

The post Why languages become endangered, and how we can keep them alive appeared first on Smithsonian Insider.

In the early 20th century, Canada geese were considered endangered in the U.S. So in the 1950s and 1960s, birds from the Midwest were released […]

The post Study of bacteria inside guts of wild Canada geese shows greater danger than earlier studies exposed appeared first on Smithsonian Insider.

Five new species of snail-eating snake, from a group of snakes affectionately known to scientists as “goo-eaters,” have been discovered by a team working in […]

The post Newly discovered snakes use curved teeth to pry snails from their shells appeared first on Smithsonian Insider.

The post The crane that fell for her keeper appeared first on Smithsonian Insider.

Death-associated protein kinase 1 (DAPK1) is a serine/threonine protein kinase that regulates apoptosis and autophagy. DAPK1 is considered to be a therapeutic target for amyloid-β deposition, endometrial adenocarcinomas and acute ischemic stroke. Here, the potent inhibitory activity of the natural anthraquinone purpurin against DAPK1 phosphorylation is shown. Thermodynamic analysis revealed that while the binding affinity of purpurin is similar to that of CPR005231, which is a DAPK1 inhibitor with an imidazopyridazine moiety, the binding of purpurin was more enthalpically favorable. In addition, the inhibition potencies were correlated with the enthalpic changes but not with the binding affinities. Crystallographic analysis of the DAPK1–purpurin complex revealed that the formation of a hydrogen-bond network is likely to contribute to the favorable enthalpic changes and that stabilization of the glycine-rich loop may cause less favorable entropic changes. The present findings indicate that purpurin may be a good lead compound for the discovery of inhibitors of DAPK1, and the observation of enthalpic changes could provide important clues for drug development.

Warner’s narrative covers the major natural sweeteners, including sugar, molasses from cane, beet sugar, corn syrup, honey and maple, as well as artificial sweeteners such as saccharin, cyclamate, aspartame and sucralose.

The post New Book: “Sweet Stuff: An American History of Sweeteners from Sugar to Sucralose” appeared first on Smithsonian Insider.