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A high-throughput system combining microfluidic hydrogel droplets with deep learning for screening the antisolvent-crystallization conditions of active pharmaceutical ingredient

Lab Chip, 2020, Accepted Manuscript
DOI: 10.1039/D0LC00153H, Paper
Zhening Su, Jinxu He, Peipei Zhou, Lu Huang, Jianhua Zhou
Crystallization of active pharmaceutical ingredients (APIs) is a crucial process in the pharmaceutical industry due to its great impact in drug efficacy. However, conventional approaches for screening the optimal crystallization...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Evaluation of intercellular communication between breast cancer cells and adipose-derived stem cells via passive diffusion in a two-layer microfluidic device

Lab Chip, 2020, Advance Article
DOI: 10.1039/D0LC00142B, Paper
Sharif M. Rahman, Joshua M. Campbell, Rachael N. Coates, Katie M. Render, C. Ethan Byrne, Elizabeth C. Martin, Adam T. Melvin
Breast cancer cells co-cultured with adipose-derived stem cells (ASCs) in a microfluidic device exhibited enhanced growth, a more aggressive morphology and polarization towards the ASCs, and increased drug resistance.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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A Web-based Automated Machine Learning Platform to Analyze Liquid Biopsy Data

Lab Chip, 2020, Accepted Manuscript
DOI: 10.1039/D0LC00096E, Paper
Hanfei Shen, Tony Liu, Jesse Cui, Piyush Borole, Ari Benjamin, Konrad Kording, David Issadore
Liquid biopsy (LB) technologies continue to improve in sensitivity, specificity, and multiplexing and can measure an ever growing library of disease biomarkers. However, clinical interpretation of the increasingly large sets...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Liquid-liquid-liquid three-phase microsystem: hybrid slug flow-laminar flow

Lab Chip, 2020, Accepted Manuscript
DOI: 10.1039/D0LC00292E, Communication
Tao Wang, Cong Xu
Liquid-liquid-liquid three-phase microfluidics provides abundant flow patterns and attractive characteristics that substantially extend the applications of liquid-liquid two-phase microfluidics. Although the manipulation of stable interfaces between adjacent liquid phases is...
The content of this RSS Feed (c) The Royal Society of Chemistry




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First look of Netaji Subhash Chandra Bose, new debate over his death




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Express newslist: Updates on Draft National Encryption Policy, beef ban and other stories




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Express newslist: Secret letter on Netaji, Bombay HC verdict on sedition and other updates




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Express News list: Hardik surfaces after disappearance, prosecution seeks death penalty for 8 in Mumbai blasts case




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Express Newslist: Modi meets Fortune 500 CEOs, Gujarat announces Rs 1,000 cr package for EW




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Express Newslist: Modi calls IS greatest challenge, Karnataka bandh, Hawala crackdown links to Dawood




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Express Newslist: Narendra Modi at Facebook townhall, SC rejects Somnath Bharti’s bail plea




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Express Newslist: Mob kills man over beef rumours; 7/11 Mumbai blast sentencing




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Express Newslist: Mumbai blasts convict’s confession, India’s reply to Pak at UN, Mahesh Sharma on Dadri lynching




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Over 10,000 students dance to spread awareness against drugs




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Express Newslist: MHA’s ‘zero tolerance’ on Dadri Lynching, jawans killed in Kupwara encounter, Khurshid Mahmud Kasuri’s new book,




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Here are the 33 writers who returned their Sahitya Akademi awards




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Putin to Modi: Here’s Forbes’ 10 most powerful people in 2015




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7th Pay Commission recommendations: All you need to know




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Rs 90 crore: What is common with this figure?




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#ie100: Narendra Modi to Ravish Kumar, the most powerful Indians




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What is Panama Papers? Here is everything you need to know




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Today’s top news: Pinarayi to swear-in as Kerala CM, UP Governor on Bajrang Dal camp and more




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See India’s first solar-powered DEMU trains




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[ASAP] SPREAD: A Fully Automated Toolkit for Single-Particle Cryogenic Electron Microscopy Data 3D Reconstruction with Image-Network-Aided Orientation Assignment

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.9b01099




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[ASAP] What Will Computational Modeling Approaches Have to Say in the Era of Atomistic Cryo-EM Data?

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.0c00123




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[ASAP] Combining Docking Pose Rank and Structure with Deep Learning Improves Protein–Ligand Binding Mode Prediction over a Baseline Docking Approach

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.9b00927




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[ASAP] What Could Go Wrong? A Practical Guide to Single-Particle Cryo-EM: From Biochemistry to Atomic Models

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.9b01178




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[ASAP] Will Cryo-Electron Microscopy Shift the Current Paradigm in Protein Structure Prediction?

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.0c00177




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[ASAP] Correction of Missing-Wedge Artifacts in Filamentous Tomograms by Template-Based Constrained Deconvolution

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.9b01111




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[ASAP] Modeling of a 14 kDa RUVBL2-Binding Domain with Medium Resolution Cryo-EM Density

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.9b01095




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[ASAP] MAINMASTseg: Automated Map Segmentation Method for Cryo-EM Density Maps with Symmetry

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.9b01110




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[ASAP] Flexible Fitting of Small Molecules into Electron Microscopy Maps Using Molecular Dynamics Simulations with Neural Network Potentials

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.9b01167




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[ASAP] Live Analysis and Reconstruction of Single-Particle Cryo-Electron Microscopy Data with CryoFLARE

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.9b01102




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[ASAP] Exploring Conformational Space with Thermal Fluctuations Obtained by Normal-Mode Analysis

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.9b01136




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[ASAP] Mechanism-Based Rational Discovery and <italic toggle="yes">In Vitro</italic> Evaluation of Novel Microtubule Stabilizing Agents with Non-Taxol-Competitive Activity

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.9b01133




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[ASAP] Brick-CFCMC: Open Source Software for Monte Carlo Simulations of Phase and Reaction Equilibria Using the Continuous Fractional Component Method

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.0c00334




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[ASAP] Discovery of Ubiquitin-Specific Protease 7 (USP7) Inhibitors with Novel Scaffold Structures by Virtual Screening, Molecular Dynamics Simulation, and Biological Evaluation

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.0c00154




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[ASAP] Ranking Molecules with Vanishing Kernels and a Single Parameter: Active Applicability Domain <italic toggle="yes">Included</italic>

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.9b01075




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[ASAP] Update to Our Reader, Reviewer, and Author Communities—April 2020

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.0c00399




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[ASAP] Context Aware Data-Driven Retrosynthetic Analysis

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.9b01141




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[ASAP] Nanomaterial Synthesis Insights from Machine Learning of Scientific Articles by Extracting, Structuring, and Visualizing Knowledge

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.0c00199




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[ASAP] BIreactive: A Machine-Learning Model to Estimate Covalent Warhead Reactivity

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.9b01058




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[ASAP] Ranking of Ligand Binding Kinetics Using a Weighted Ensemble Approach and Comparison with a Multiscale Milestoning Approach

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.9b00968




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'WTA merger with ATP not be acquisition'

Roger Federer called for a merger between the two governing bodies last month, with both Simon and ATP Tour Chairman Andrea Gaudenzi welcoming the suggestion.




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Who is the greatest tennis player?

Eight-time Grand Slam winner Ivan Lendl said whoever ends up winning the most majors among the 'Big Three' of Roger Federer, Rafa Nadal and Novak Djokovic should be considered the greatest male tennis player of the Open era. Federer, who will be 39 in August, leads the race with 20 Grand Slam singles titles, with Spaniard Nadal close on his heels with 19. Reigning world No. 1 Djokovic is three behind the Swiss with 17 majors under his belt and is the youngest of the trio - at 32 he is a year younger than Nadal.




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French Muslims in Perspective: Nationalism, Post-Colonialism and Marginalisation under the Republic / Joseph Downing

Online Resource




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Pope Francis as a global actor: where politics and theology meet / Alynna J. Lyon, Christine A. Gustafson, Paul Christopher Manuel, editors

Online Resource




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Beyond the self: conversations between Buddhism and neuroscience / Matthieu Ricard and Wolf Singer

Hayden Library - BQ4570.N48 R5313 2017




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The chosen wars: how Judaism became an American religion / Steven R. Weisman

Hayden Library - BM205.W45 2018




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The Islamic enlightenment: the struggle between faith and reason: 1798 to modern times / Christopher de Bellaigue

Hayden Library - BP166.14.M63 D42 2018