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Nanocrystalline alloy-mediated delivery of mosaic epitope peptides for universal influenza vaccine

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB00742E, Paper
Hongyu Wang, Han Fu, Liyan Zhai, Jiaqing Le, Bohan Guo, Yuyang Zhou, Chenlin Ji, Dapeng Li, Yue Zhang
Mosaic influenza antimicrobial peptide-like epitopes (Ampitopes) co-crystalize with poly(I:C), a TLR3 agonist, into nanocrystalline vaccine, which boosts immunogenicity via multivalent toll like receptor 3 (TLR3) binding and immune activation.
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One-pot rapid preparation of long-term antioxidant and antibacterial biomedical gels based on lipoic acid and eugenol for accelerating cutaneous wound healing

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01844C, Paper
Yungang Feng, Fangrui Xie, Rui Ding, Qingrong Zhang, Youzhi Zeng, Li Li, Lianbin Wu, Yunlong Yu, Linxuan Fang
A medical antibacterial gel with long term and high antioxidant activity prepared from eugenol and lipoic acid showed good tissue repair and regeneration for burns and trauma.
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Reconfiguring the endogenous electric field of a wound through a conductive hydrogel for effective exudate management to enhance skin wound healing

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01349B, Communication
Yukun Yan, Yuanyuan Chen, Hanqing Dai, Wanlu Zhang, Ruiqian Guo
In this work, we proposed a mechanism for hydrogel-based dressings to respond to endogenous electric fields through exudate absorption and conducted a verification study using polyacrylamide and sodium alginate (PAM–SA) hydrogels.
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Sodium lanthanide tungstate-based nanoparticles as bimodal contrast agents for in vivo high-field MRI and CT imaging

J. Mater. Chem. B, 2024, 12,11123-11133
DOI: 10.1039/D4TB01157K, Paper
Open Access
Elisabet Gómez-González, Carlos Caro, Nuria O. Núñez, Daniel González-Mancebo, Jesús D. Urbano-Gámez, Maria L. García-Martín, Manuel Ocaña
NaLn(WO4)2 (Ln = Dy or Ho) nanoparticles functionalized with polyacrylic acid exhibit excellent performance as bimodal contrast agents for high-field MRI and X-ray computed tomography bioimaging and show tumor targeting ability through the EPR effect.
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A dual-functional photosensitizer for mitochondria-targeting photodynamic therapy and synchronous polarity monitoring

J. Mater. Chem. B, 2024, 12,11259-11264
DOI: 10.1039/D4TB01872A, Paper
Liu Yang, Shenglong Gan, Jie Zhang, Yin Jiang, Qingxin Chen, Hongyan Sun
A dual-functional photosensitizer was developed, exhibiting potent phototoxicity and sensitivity to polarity changes.
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Advances in osteoimmunomodulation of biomaterials after intrabone implantation: focus on surface hydrophilicity

J. Mater. Chem. B, 2024, 12,11089-11104
DOI: 10.1039/D4TB01907E, Review Article
Xinpeng Wei, Linshan Lei, Ling Luo, Ying Zhou, Zheng Zheng, Wenchuan Chen
Hydrophilicity of implantable biomaterials can facilitate osteoimmunomodulation through influencing proteins adsorption, blood clotting, neutrophils activation, macrophages polarization, angiogenesis and osteogenesis to enhance osseointegration.
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Chitosan-functionalized nanobubbles for precision oncology: advances in targeted cancer therapeutics

J. Mater. Chem. B, 2024, 12,11076-11088
DOI: 10.1039/D4TB01930J, Review Article
Vivek Pandey, Tejasvi Pandey
The convergence of nanotechnology and cancer therapeutics has opened new frontiers in the development of advanced drug delivery systems.
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Microfluidic synthesis and accurate immobilization of low-density QD-encoded magnetic microbeads for multiplex immunoassay

J. Mater. Chem. B, 2024, 12,11230-11236
DOI: 10.1039/D4TB01585A, Paper
Zhou Sha, Tianyi Ling, Wenqi Yang, Haosu Xie, Chunnan Wang, Shuqing Sun
Accurate immobilization of microbeads in the gap of nickel patterns.
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Breakthrough in cancer therapy: lutetium texaphyrin–celecoxib conjugate for immune and photodynamic treatment

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB02019G, Highlight
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Qihang Ding, Yue Wang, Pengfei Zhang, Ling Mei
Kim et al. present a small-molecule photosensitizer, LuCXB, which combines a COX-2 inhibitor (celecoxib) with a near-infrared lutetium texaphyrin photocatalyst and was loaded CD133-aptamer functionalized exosome for cancer stem cells targeting.
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A guanidiniocarbonyl-pyrrole functionalized cucurbit[7]uril derivative as a cytomembrane disruptor for synergistic antibacterial therapy

J. Mater. Chem. B, 2024, 12,11105-11109
DOI: 10.1039/D4TB01840K, Communication
Ruixue Han, Kehan Du, Shengke Li, Minzan Zuo, Ponmani Jeyakkumar, Hao Jiang, Leyong Wang, Xiao-Yu Hu
A guanidiniocarbonyl-pyrrole functionalized cucurbit[7]uril derivative as a cytomembrane disruptor has been successfully constructed for synergistic antibacterial therapy.
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An innovative electrohydrodynamics-driven SERS platform for molecular stratification and treatment monitoring of lung cancer

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01434K, Highlight
Tuotuo Zhang, Biao Dong, Huiling Wang, Shuai Zhang
A schematic electrohydrodynamics-driven SERS platform to profile four proteins on sEVs to generate a unique molecular signature for lung cancer stratification.
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Biomaterials Enhancing Localized Cancer Therapy Activated Anti-Tumor Immunity: A Review

J. Mater. Chem. B, 2024, Accepted Manuscript
DOI: 10.1039/D4TB01995D, Review Article
Jipeng Yao, Zhencun Cui, Feifei Zhang, Haidong Li, Longlong Tian
Localized cancer therapy such as radiotherapy, phototherapy, and chemotherapy are precise cancer treatment strategy, aiming to minimize systemic side effect. However, cancer metastasis remains the primary cause of cancer patients’...
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Unravelling the molecular mechanobiology by DNA-Based fluorogenic tension sensor

J. Mater. Chem. B, 2024, Accepted Manuscript
DOI: 10.1039/D4TB01858C, Review Article
Kaushik Pal
Investigation of the biological system reveals many underlying principles that govern the regular life processes. Recently, the analysis of tiny mechanical forces associated with many biological processes revels their significance...
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A water playground for peptide re-assembly from fibrils to plates

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01727G, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Simone Adorinni, Marina Kurbasic, Ana M. Garcia, Slavko Kralj, Ottavia Bellotto, Erica Scarel, Paolo Pengo, Rita De Zorzi, Michele Melchionna, Attilivio V. Vargiu, Silvia Marchesan
Water plays a key role in the irreversible transition from peptide fibrils to plates.
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Eco-Friendly Self-Clean Coatings: Fundamentals, Fabrication, Applications, and Sustainability

J. Mater. Chem. B, 2024, Accepted Manuscript
DOI: 10.1039/D4TB01392A, Review Article
Tanaji K. Chavan, Sushanta Kumar K. Sethi
Eco-friendly self-clean coatings have garnered significant attention due to their potential to address environmental concerns while offering remarkable properties. This review explores the dynamic field of such coatings, focusing on...
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Functionalities of pH-responsive DNA nanostructures in tumor-targeted strategies

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01883D, Review Article
Liyue Wen, Min Wang
Design and application of various pH-responsive DNA nanostructures for tumor-targeted strategies toward extracellular and intracellular environments are comprehensively reviewed. Their potential and challenges are also critically discussed.
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Illuminating cisplatin-induced ferroptosis in non-small-cell lung cancer with biothiol-activatable fluorescent/photoacoustic bimodal probes

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01656D, Paper
Li Xu, Hongwen Liu, Yi Kong, Lingyun Li, Jia Li, Kang Li, Shuzhi Liang, Bolin Chen
Using activatable NIR fluorescent/PA bimodal probes, we successfully monitored real-time biothiol changes during ferroptosis in NSCLC cells and tumors, revealing enhanced ferroptosis with the combined use of erastin and cisplatin.
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Dual-functional PCN-242 (Fe2Co) MOF for sensitive bacterial endotoxin detection

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01944J, Paper
Sivasankar Kulandaivel, Yung-Kang Lu, Chia-Her Lin, Yi-Chun Yeh
This work introduces a novel bimetallic MOF with superior endotoxin detection and enhanced catalytic activity for broader diagnostic applications.
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Micah Parsons insists he wasn't throwing "Mike McCarthy under the bus" with postgame comments

Cowboys edge rusher Micah Parsons pushed back against the perception he was taking a shot at coach Mike McCarthy in his postgame comments Sunday.











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If not TV, what is young India watching?

According to industry experts, television has lost the young urban viewer for English or Hindi shows. Urvi Malvania finds out what is making more and more of them turn to digital platforms like Voot and Hotstar.





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PIX: The Kaun Banega Crorepati Season 9 shoot begins

A look at the first day's pictures.




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Meet Kaun Banega Crorepati's first crorepati

'The moment he said my answer was right, I wanted to cry with happiness. But I did not want to cry in front of everyone and spoil my kajal. But I couldn't control my tears' Anamika Majumdar looks back at her winning moment on Kaun Banega Crorepati.








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Bigg Boss 11: 'It is 100% true. I love Puneesh'

'I can't fake love for the cameras.'












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Bigg Boss 16: Shalin Kisses Soundarya

With each passing day, the equations are changing and the contestants are slowly showing their true personality.




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Bigg Boss 16: Is Soundarya Dominating?

With so many equations changing everyday, the Bigg Boss game is finally beginning to seem exciting.




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Is Varun Going To Be A Daddy?

Though Archana Gautam was evicted from Bigg Boss for physically hurting Shiv Thakare, the actress-turned-politician was brought back in the game over the weekend.




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Bigg Boss 16: Why Sajid Needs To Be Punished!

Sajid Khan has never been grilled for his behaviour and it's becoming more and move evident that the makers are favouring him on the show.




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Bigg Boss 16: Will Soundarya Get Evicted? PREDICT!

After Gautam Vig, will his rumoured girlfriend Soundarya Sharma exit the Bigg Boss house?




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Actor Tunisha Sharma commits suicide on TV show set

Sharma went to the washroom on the set and did not return for a long time. When the door was broken down, she was found hanging inside, he said.




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'Women don't understand women'

'In a family, your mother-in-law or sister-in-law are your core team.''If they don't support you, it becomes very difficult.'