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Stanley Cup champion Panthers and coach Paul Maurice agree to contract extension

The Florida Panthers have given out another big extension — this one, to their Stanley Cup-winning coach. Paul Maurice and the Panthers have agreed on an extended contract, the team announced Tuesday.



  • Sports/Hockey/NHL

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Maple Leafs legend Mats Sundin looks back on his playing career in 'Home and Away'

In his new book, former Maple Leafs captain Mats Sundin dives into the pressures and anxieties of being the first European drafted first overall to the NHL, getting traded by Quebec Nordiques to Toronto for Wendel Clark, and the turbulent end to his time with the team.



  • Sports/Hockey/NHL

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Ex-Penguins goalie Marc-André Fleury bids farewell to Pittsburgh fans on retirement tour

Marc-André Fleury stopped 26 shots in what will likely be his final game in Pittsburgh as the Minnesota Wild beat the Penguins 5-3 on Tuesday night. He spent 13 seasons with Pittsburgh and won Stanley Cups in 2009, 2016 and 2017.



  • Sports/Hockey/NHL

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Kamala Harris drinks wine and plays Connect 4 in joyful post-election pic posted by her niece

What would you do if you'd just been dealt a devastating, extremely public defeat? If your answer is "drink wine in leggings," then Vice-President and former Democratic U.S. presidential candidate Kamala Harris can do you one better: Drink wine in leggings, sporting a messy bun, while playing Connect 4.




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Crime network selling Banksy, Warhol and Picasso forgeries uncovered in Italy

Italian police have uncovered a large-scale pan-European forgery network making and selling fake artworks attributed to some of the biggest names in modern and contemporary art including Banksy, Pablo Picasso and Andy Warhol.




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Israeli strikes kill 37 as attacks intensify in central and southern Gaza

An Israeli airstrike killed seven people late Monday at a café near the southern Gaza city of Khan Younis, Palestinian medics said, bringing the death toll from Israeli strikes since Sunday night to at least 37.




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Thousands march in far-right rally to mark Poland's Independence Day

Tens of thousands of Poles including nationalist opposition chiefs walked through Warsaw on Monday in an annual Independence Day event held by the far right, some shooting red flares and carrying anti-EU, anti-Ukraine and white supremacist banners.




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Driver deliberately rams car into crowd in China, killing 35 and injuring dozens

A driver killed 35 people and severely injured another 43 when he deliberately rammed his car into people exercising at a sports centre in the southern Chinese city of Zhuhai, police said Tuesday.




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Church of England head Justin Welby resigns after sex abuse coverup controversy

An investigation found that he failed to inform police about serial physical and sexual abuse by a volunteer at Christian summer camps as soon as he became aware of it.




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Tens of thousands declare early to avoid Toronto's vacant home tax

Toronto's redesigned vacant home tax rollout has begun, with over 59,000 people filing their paperwork in the first week. Some councillors say they were left responding to complaints about the rollout, after the city's online declaration portal experienced technical problems shortly after launch.



  • News/Canada/Toronto

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Brampton reaches deal with striking city workers, mayor and union say

Brampton has reached a tentative deal with nearly 1,200 city workers who have been on strike since last week, according to Mayor Patrick Brown and the union.



  • News/Canada/Toronto

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Alberta hiring to restore land where fireguards were created in 2023 wildfire season

The provincial government is seeking contractors to restore hundreds of kilometres of land where fireguards were created during the 2023 wildfire season.



  • News/Canada/Edmonton

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2-year-old western lowland gorilla Eyare dies at Calgary Zoo

Eyare died of injuries she sustained while moving between back of house spaces, Wilder Institute director of animal care, health and welfare, Colleen Baird said Tuesday.



  • News/Canada/Calgary

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Homan and Morris' Olympic appointment is 'what every curler dreams of'

Rachel Homan and John Morris join That Curling Show fresh off the news they have been chosen to represent Canada in mixed doubles curling at the Beijing Olympics.




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Pandemic continues to impact curling events across northern Ontario

As some qualifying events in curling get cancelled, organizers in this region and across the country are starting to have to choose teams based on a ranking system to determine who gets to compete.



  • News/Canada/Sudbury

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CME Group Inc. Reports All-Time Record Revenue, Adjusted Operating Income, Adjusted Net Income and Adjusted Earnings Per Share for Q3 2024

Record revenue of $1.6 billion Record quarterly ADV of 28.3 million contracts - the second consecutive quarter of volume, open interest growth across every asset class CHICAGO, Oct. 23, 2024...




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Henry Hub Futures Reach Record Open Interest as International Demand Soars

CME Group, the world's leading derivatives marketplace, today announced that open interest in its global benchmark Henry Hub futures contract reached a record 1.73 million contracts on October 30,...




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CME Group Announces Employment Agreement Extension for Chairman and Chief Executive Officer Terry Duffy

Chief Financial Officer Lynne Fitzpatrick Appointed to President and CFO Chief Operating Officer Julie Holzrichter to Step Down and Assume Advisory Role Suzanne Sprague to Succeed Holzrichter CHICAGO,




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Introduction to Techniques Used to Study Mosquito Neuroanatomy and Neural Circuitry

Mosquitoes transmit deadly pathogens from person to person as they obtain the blood meal that is essential for their life cycle. Female mosquitoes of many species are unable to reproduce without consuming protein that they obtain from blood. This developmental stage makes them highly efficient disease vectors of deadly pathogens. They can transmit pathogens between members of the same species and different species that can provide a route for evolving zoonotic viruses to jump from animals to humans. One possible way to develop novel strategies to combat pathogen transmission by mosquitoes is to study the sensory systems that drive mosquito reproductive behaviors, in particular the neural architecture and circuits of mosquito sensory afferent neurons, the central circuits that process sensory information, and the downstream circuits that drive reproductive behaviors. The study of mosquito neuroanatomy and circuitry also benefits basic neuroscience, allowing for comparative neuroanatomy in insect species, which has great value in the current model species-heavy landscape of neuroscience. Here, we introduce two important techniques that are used to study neuroanatomy and neural circuitry—namely, immunofluorescent labeling and neural tracing. We describe how to apply these approaches to study mosquito neuroanatomy and describe considerations for researchers using the techniques.




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Whole-Brain Electrophysiology and Calcium Imaging in Drosophila during Sleep and Wake

Sleep is likely a whole-brain phenomenon, with most of the brain probably benefiting from this state of decreased arousal. Recent advances in our understanding of some potential sleep functions, such as metabolite clearance and synaptic homeostasis, make it evident why the whole brain is likely impacted by sleep: All neurons have synapses, and all neurons produce waste metabolites. Sleep experiments in the fly Drosophila melanogaster suggest that diverse sleep functions appear to be conserved across all animals. Studies of brain activity during sleep in humans typically involve multidimensional data sets, such as those acquired by electroencephalograms (EEGs) or functional magnetic resonance imaging (fMRI), and these whole-brain read-outs often reveal important qualities of different sleep stages, such as changes in frequency dynamics or connectivity. Recently, various techniques have been developed that allow for the recording of neural activity simultaneously across multiple regions of the fly brain. These whole-brain-recording approaches will be important for better understanding sleep physiology and function, as they provide a more comprehensive view of neural dynamics during sleep and wake in a relevant model system. Here, we present a brief summary of some of the findings derived from sleep activity recording studies in sleeping Drosophila flies and discuss the value of electrophysiological versus calcium imaging techniques. Although these involve very different preparations, they both highlight the value of multidimensional data for studying sleep in this model system, like the use of both EEG and fMRI in humans.




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Design and Validation of Guide RNAs for CRISPR-Cas9 Genome Editing in Mosquitoes

CRISPR–Cas9 has revolutionized gene editing for traditional and nontraditional model organisms alike. This tool has opened the door to new mechanistic studies of basic mosquito biology as well as the development of novel vector control strategies based on CRISPR–Cas9, including gene drives that spread genetic elements in the population. Although the promise of the specificity, flexibility, and ease of deployment CRISPR is real, its implementation still requires empirical optimization for each new species of interest, as well as to each genomic target within a given species. Here, we provide an overview of designing and testing single-guide RNAs for the use of CRISPR-based gene editing tools.




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Mosquito Egg Development and Eggshell Formation

Anautogenous female mosquitoes, which ingest a blood meal from warm-blooded vertebrates to produce eggs, have become a valuable model organism for investigating signaling pathways and physiological processes that occur during egg development. Different molecular pathways tightly regulate the initiation of egg development and are governed by a balance among different insect hormones. Gravid (mature egg-carrying) females deposit fully developed eggs at the end of each gonotrophic cycle, which is defined as the time interval between the ingestion of a blood meal to oviposition. An intact eggshell protects the oocyte and embryo inside from external factors such as desiccation, physical damage, etc., and the various eggshell proteins are spatially and temporary deposited during oogenesis. Additionally, follicle resorption (oosorption) during blood meal–induced mosquito ovarian follicle development is an adapted physiological process that optimizes reproductive fitness. Mosquito oocytes grow and mature synchronously throughout oogenesis; however, during the later stages of oogenesis, some oocytes may undergo oosorption if sufficient nutrients are unavailable. This introduction highlights how mosquito egg development can be used to investigate follicular resorption and identify proteins involved in eggshell formation in Aedes aegypti mosquitoes.




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Standing room only

When OM Montenegro began in 2007 with a team of three, holding a full Sunday meeting seemed a long way off—but not anymore.




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From Scotland, with love

With the help of two Scottish special-needs teachers, OM Montenegro passionately improves the lives of children with autism and the lives of their families.




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Amendments to the Listing Schedule, Delisting of Previously-Listed Contract Months and Subsequent Permanent Delisting of the U.S. Midwest #1 Busheling Ferrous Scrap (AMM) Futures Contract




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Amendments to the Floating Price Rule of the Cobalt Hydroxide CIF China (Fastmarkets) Futures Contract Commencing with the January 2026 Contract Month and Beyond




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Amendments to the Effective Date of the Delivery Eligibility Requirements of the Gold, Gold Kilo, and Gold (Enhanced Delivery) Futures Contracts




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Initial Listing of the Gulf Coast UCO (Argus) (60,000 lb) Futures and the Gulf Coast UCO (Argus) Futures Contracts




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Expansion of the Listing Schedule of the New Crop Weekly Corn and New Crop Weekly Soybean Option Contracts




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Amendments to Chapter 12 (CME Spot Call Trading – Electronic) in Connection with Spot Call Nonfat Dry Milk, Spot Call Butter, Spot Call Cheese, and Spot Call Dry Whey




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PEAK Surgical Uses SolidWorks Software to Develop Low-Temperature Surgical Cutting and Coagulation Tools

Pioneering Technology Allows Surgeons to Cut Precisely and Control Bleeding Without Causing Heat Damage to Tissue




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MAKO uses SolidWorks software to design robotics and implants for minimally invasive surgery alternative

Knee replacement doesn’t have to be ‘total’




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Aqualux drains wasted time out of shower design with SolidWorks and 3DVIA

Quick design turnaround and easy documentation process help UK-based company move products to market faster




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Microsoft and DS SolidWorks Enhance Robot Simulation

Robotics programmers can now use SolidWorks 3D CAD models for more powerful simulations




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SolidWorks World 2009 to Feature Exciting Keynotes, Success Stories, and Learning Opportunities

Sir Richard Branson, Jeff Ray, Jon Hirschtick, and World-Class Companies to Shine at World’s Largest Annual SolidWorks Gathering




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Felder accelerates design of woodworking machines with SolidWorks software and 3DVIA Composer

Austrian manufacturer also optimizes creation of assembly documentation and related bills of material




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SolidWorks 3D ContentCentral 2009 Blends Social Media and Self-Publishing Into Community for Sharing Design Knowledge

Eliminates the Cost and Complexity of Maintaining Online Parts Catalogs; Improves Search, Navigation, and Communication for Engineers Seeking 3D Part Models




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SolidWorks World: ‘Valuable’ and ‘Inspirational’

SolidWorks World 2009 Wraps Up Exhilarating Week of Learning and Networking




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DS SolidWorks Education Edition 2009 Expands Access To Advanced CAD Functionality While Boosting Performance

New Licensing, Support Programs For Certification Accompany Software Upgrades




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Wittur Group Standardizes on SolidWorks Enterprise PDM to Create Global Collaboration Network of Designers

Leading elevator components supplier implements 550 licenses of the SolidWorks PDM solution




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Same Game, Better Ice Rinks with Sport Systems Unlimited and SolidWorks Software

Maker of NHL Hockey Boards Uses SolidWorks and Robotics to Speed Production by More than 60 Percent




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National Instruments and SolidWorks Collaborate on a Virtual Prototyping Solution

Integrated Tools Make Mechatronics-Oriented Design and Seamless Deployment to Hardware Easy