us Not exclusively the activity, but the sweet spot: a dehydrogenase point mutation synergistically boosts activity, substrate tolerance, thermal stability and yield By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, 22,3009-3018DOI: 10.1039/D4OB00211C, PaperYu-Ke Cen, Lin Zhang, Yue Jiang, Xiang-Fu Meng, Yuan Li, Chao Xiang, Ya-Ping Xue, Yu-Guo ZhengA single-point mutation of 7α-HSDH achieved the highest activity and synergistically improved substrate tolerance, thermal stability, cofactor affinity, and conversion rate.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
us Selective synthesis of an elusive C-functional bis-cyclam and study of its inhibition of the CXCR4 chemokine receptor By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, 22,3059-3067DOI: 10.1039/D3OB02050A, PaperMarie M. Le Roy, Sandra Claes, Nathalie Saffon-Merceron, Dominique Schols, Thibault Troadec, Raphaël TripierA rare example of C,C'-linked bis-cyclam has been synthesized with controlled manner in mild conditions thanks to the “bis-aminal” tool, and its good CXCR4-recognition properties could be demonstated in vitro.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
us Hydrosilylation of nitriles and tertiary amides using a zinc precursor By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, 22,3053-3058DOI: 10.1039/D4OB00161C, PaperRavi Kumar, Rohan Kumar Meher, Himadri Karmakar, Tarun K. PandaA competent and selective hydrosilylation of nitriles and tertiary amides catalyzed by zinc bis(hexamethyldisilazide) [Zn(HMDS)2] under solvent-free and mild conditions are reported, as a sustainable and desirable alternative to existing methods.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
us Unusual immunosuppressive pyridine-containing bisnor- (c23), tetranor- (c21) and pentanor- (c20) sesterterpenoids from Tibetan Leucosceptrum canum By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, 22,3019-3024DOI: 10.1039/D4OB00334A, PaperMan Li, Ling Feng, Han Zhang, Yan-Chun Liu, Ting-Ting Zhou, Yu Zheng, Kai Guo, Yan Liu, Sheng-Hong LiSix unusual pyridine-containing bisnor- (C23), tetranor- (C21) and pentanor- (C20) sesterterpenoids were obtained from the medicinal plant Leucosceptrum canum of Tibetan origin. The immunosuppressive activities of these sesterterpenoids were observed.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
us Palladium-catalyzed (Z)-selective allylation of phosphine oxides with vinylethylene carbonates to construct phosphorus allyl alcohols By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, 22,3068-3072DOI: 10.1039/D4OB00354C, PaperHua Huang, Yi-Qi Wu, Lu-Yao Han, Lu Jiang, Zhuo-Zhuo Zhang, Xiang Zhang, Bo Han, Wei Huang, Jun-Long LiA general and efficient method for the highly stereoselective synthesis of (Z)-phosphorus allylalcohols has been developed using the Pd-catalyzed cross-coupling of phosphine oxides with vinylethylene carbonates.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
us Charge-transfer inclusion complex formation of the tropylium cation with prism[6]arenes By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, Advance ArticleDOI: 10.1039/D4OB00423J, CommunicationGuojiao Zhang, Channi Cheng, Zhengxiang Li, Dezhi Zhao, Chengyou HanWe report that charge-transfer (CT) inclusion complexes were formed between prism[6]arenes and tropylium cation. Additionally, the CT complex showed Cl−/Ag+ responsiveness which can be easily monitored by the naked eye.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
us TEMPO/PhI(OAc)2 promotes the α-aminophosphinoylation of alcohols with amines and H-phosphine oxides in aqueous medium By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, Advance ArticleDOI: 10.1039/D4OB00302K, CommunicationQiang Huang, Xin Jin, Lvjia Wu, Jiangdong Li, Qianlu Xing, Xianheng Wang, Changkuo ZhaoThe aminophosphinoylation of alcohols with amines and H-phosphine oxides provides an efficient and mild approach to access various α-aminoalkylphosphine oxides in good yields with good tolerance of functional groups using H2O as a clean solvent.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
us An FeCl3-catalyzed three-component reaction for the synthesis of β-(1,2,3-triazolyl)-ketones using DMF as a one-carbon source By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, Advance ArticleDOI: 10.1039/D4OB00207E, CommunicationRuilin Fang, Lei Zheng, Xuyang Chen, Can Wang, Yunfeng ChenFeCl3-catalyzed oxidative condensation of NH-1,2,3-triazoles and aryl methyl ketones and DMF has been reported.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
us Sustainable preparation of 2-acylbenzothiazoles under the cooperation of ionic liquids and microwave irradiation By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, Advance ArticleDOI: 10.1039/D4OB00315B, PaperShoushun Wang, Mengjie Liu, Yiyuan Yue, Xiude Hu, Yalin Zhang, Guodong Shen, Ruiguo Dong, Lilong Shi, Bing Yu, Xianqiang HuangA series of 2-acylbenzothiazole derivatives were sustainably synthesized for the first time under the cooperation of ionic liquids and microwave irradiation, metal- and extra-additives-free conditions.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
us Regioselective synthesis of 4-arylamino-1,2-naphthoquinones in eutectogel as a confined reaction medium using LED light By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, Advance ArticleDOI: 10.1039/D4OB00140K, CommunicationR. Vara Prasad, Yogendra Kumar, R. Arun Kumar, Tohira Banoo, Subbiah NagarajanThe use of a simple carbohydrate-derived eutectogel facilitating a LED-light-induced regioselective synthesis of 4-arylamino-1,2-naphthoquinones in good yields is reported.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
us Getting Started with CSS Shapes: Wrapping content around custom paths By www.html5rocks.com Published On :: Tue, 16 Sep 2014 00:00:00 +0000 Using CSS Shapes we can create experiences that we have never been able to create on the web before. Full Article
us Introduction to Service Worker: How to use Service Worker By www.html5rocks.com Published On :: Mon, 01 Dec 2014 00:00:00 +0000 Service Worker will revolutionize the way we build for the web. Learn about what it is, why it is important and how to use it. Full Article
us A time when hijackings were dime-a-dozen in the US By www.thehindubusinessline.com Published On :: Sun, 27 Jun 2021 13:07:20 +0530 Unthinkable in today’s hyper-security post-9/11 environment, forced diversions were commonplace in the ’60s Full Article Flight Plan
us ‘The challenge was in getting the aircraft’s custom clearance’ By www.thehindubusinessline.com Published On :: Sun, 22 Aug 2021 15:46:05 +0530 Private jet operator JetSetGo’s CEO Kanika Tekriwal describes the intricacies of directly importing and leasing an aircraft Full Article Flight Plan
us Airbus responds to COP26 By www.thehindubusinessline.com Published On :: Sun, 28 Nov 2021 18:10:46 +0530 Full Article Flight Plan
us A380: How Airbus forecast misfired By www.thehindubusinessline.com Published On :: Sun, 26 Dec 2021 18:20:55 +0530 Sinks $25 billion in the process Full Article Flight Plan
us Robust flight plans can keep airlines afloat By www.thehindubusinessline.com Published On :: Sun, 09 Jan 2022 18:02:18 +0530 Full Article Flight Plan
us Deep tech is helping airlines sustain operations during Covid By www.thehindubusinessline.com Published On :: Mon, 24 Jan 2022 09:51:21 +0530 Integrated biometric-enabled frameworks for real-time test results, travel details and vaccine status are key to making air travel safe Full Article Flight Plan
us As India builds its newest airports, it needs robust, fail-proof SOPs By www.thehindubusinessline.com Published On :: Mon, 24 Jan 2022 10:23:59 +0530 A near air mishap on Bengaluru skies that put the lives of 430 people in danger shows safety risk norms require constant refresh Full Article Flight Plan
us Next order of business for Tata Sons By www.thehindubusinessline.com Published On :: Sun, 06 Feb 2022 16:53:48 +0530 How will Tata Sons turn around all the airlines under its fold, except maybe the Kochi-based Air India Express? Full Article Flight Plan
us Aviation industry shifts focus to digital By www.thehindubusinessline.com Published On :: Sun, 03 Apr 2022 18:39:12 +0530 The pandemic has helped usher in automated touchpoints for tech-savvy flight passengers Full Article Flight Plan
us Domestic airline industry may face a rejig By www.thehindubusinessline.com Published On :: Sun, 17 Apr 2022 20:18:03 +0530 The pandemic laid bare fault-lines within India’s airlines Full Article Flight Plan
us Sustainable aviation fuels could be a game-changer By www.thehindubusinessline.com Published On :: Sun, 01 May 2022 18:55:45 +0530 But adopting it in Indian aviation could take time Full Article Flight Plan
us Thrust reversal in aircraft By www.thehindubusinessline.com Published On :: Sun, 26 Jun 2022 19:14:59 +0530 It functions by directing the thrust produced by the plane’s jet engines forward, rather than backwards Full Article Flight Plan
us Will Akasa Air’s contra bet on Boeing 737 Max instead of Airbus pay off? By www.thehindubusinessline.com Published On :: Sun, 07 Aug 2022 20:00:00 +0530 Rakesh Jhunjhunwala’s Akasa airline has gone against the tide, placing its bets on Boeing aircrafts; it now needs to carve out a niche for itself Full Article Flight Plan
us 5 things Indian airlines must do to break their way out of pandemic blues By www.thehindubusinessline.com Published On :: Sun, 21 Aug 2022 21:00:00 +0530 Post pandemic, the airlines must revamp strategies and resort to long-term measures to recover from the crisis Full Article News
us Mission to Net Zero: Aviation’s focus on making sustainable connections By www.thehindubusinessline.com Published On :: Sun, 21 Aug 2022 21:00:00 +0530 Flying the cleanest, greenest, youngest fleet possible can be a way towards the goal Full Article Flight Plan
us Reviving businesses will benefit from air cargo’s growth By www.thehindubusinessline.com Published On :: Sun, 16 Oct 2022 21:00:00 +0530 India’s air cargo industry is well positioned to scale up further, thanks to a strong airport cargo infrastructure Full Article Flight Plan
us Zomato users can now schedule order 2 days in advance By www.thehindu.com Published On :: Sat, 26 Oct 2024 12:28:47 +0530 Zomato’s order scheduling is available at more than 35,000 restaurants across 30 cities Full Article Internet
us Google brings AI-powered Gmail writing tools and ‘Polish’ to more users By www.thehindu.com Published On :: Tue, 29 Oct 2024 13:29:48 +0530 Google is expanding its generative AI-powered email drafting tools to more users with new and enhanced shortcuts on web and mobile Full Article Technology
us Google ad change could affect millions of small businesses By www.thehindu.com Published On :: Wed, 30 Oct 2024 09:22:43 +0530 Google is changing the way its Google Local Services ads work, which could affect millions of small businesses Full Article Technology
us Elon Musk's xAI in talks to raise funding valuing it at $40 billion: Report By www.thehindu.com Published On :: Wed, 30 Oct 2024 09:57:24 +0530 Earlier in October, OpenAI raised $6.6 billion in funding from investors which could value the company at $157 billion Full Article Technology
us Google Maps adds AI features to help users explore and navigate the world around them By www.thehindu.com Published On :: Fri, 01 Nov 2024 08:37:38 +0530 Google Maps is heading down a new road steered by artificial intelligence Full Article Technology
us Chinese researchers develop AI model for military use on back of Meta's Llama By www.thehindu.com Published On :: Fri, 01 Nov 2024 09:59:35 +0530 ChatBIT was fine-tuned and "optimised for dialogue and question-answering tasks in the military field", the paper said Full Article Technology
us OpenAI CEO Sam Altman says next big AI model launch pushed due to compute challenges By www.thehindu.com Published On :: Fri, 01 Nov 2024 11:49:45 +0530 Altman also said that the next update for DALL-E was still in the works with no release date yet Full Article Technology
us Karnataka government plans to start 11 medical colleges under contentious PPP model By www.thehindu.com Published On :: Sun, 20 Oct 2024 21:20:19 +0530 As of now, the State has 22 government medical colleges in 22 districts while 11 others have no government medical colleges; the PPP model however has been criticised by some experts Full Article Health
us Why did the Centre sanction a 50% hike in prices of commonly-used drugs? By www.thehindu.com Published On :: Fri, 25 Oct 2024 06:00:00 +0530 According to the government the recent 50% hike in prices of eight drugs was sanctioned keeping in mind the larger public interest and to ensure continued availability of drugs Full Article Health
us For type 2 diabetes, focusing on when you eat – not what – can help control blood sugar By www.thehindu.com Published On :: Fri, 25 Oct 2024 16:07:10 +0530 Time-restricted eating, also known as the 16:8 diet, became popular for weight loss around 2015. Studies have since shown it is also an effective way for people with type 2 diabetes to manage blood glucose Full Article Health
us OpenAI’s Whisper transcription tool used in hospitals invents things no one ever said, researchers claim By www.thehindu.com Published On :: Mon, 28 Oct 2024 08:21:00 +0530 Whisper is a popular transcription tool powered by artificial intelligence, but it has a major flaw Full Article Technology
us Roll back approval to import used medical devices, med-tech industry urges PM By www.thehindu.com Published On :: Mon, 28 Oct 2024 20:20:33 +0530 The group said the move puts at risk patient safety and undermines the domestic med-tech sector. It said that refurbished machines are not subject to stringent quality checks applicable to new devices. Full Article India
us Ayushman Bharat: All seniors above 70 can avail health coverage except those in Delhi, West Bengal By www.thehindu.com Published On :: Tue, 29 Oct 2024 14:16:54 +0530 Senior citizens eligible for PM-JAY regardless of income; Ayushman Vaya Vandana card will help cut out-of-pocket health spends; on Ayurveda Day, PM launches initiatives to validate traditional herbal medicine, promote Indian medical systems Full Article India
us Lifestyle changes a major cause for stroke, say doctors By www.thehindu.com Published On :: Tue, 29 Oct 2024 21:11:08 +0530 Speaking at a public awareness meeting organised at GRH on the occasion of World Stroke Day on Tuesday, Dr. Murugan, attributed these negative factors to a sedentary lifestyle because of the youth’s job nature and location Full Article Madurai
us Air passenger with suspected mpox symptoms isolated at Tiruchi govt. hospital By www.thehindu.com Published On :: Sat, 02 Nov 2024 12:40:52 +0530 When contacted, a senior hospital official told The Hindu that the patient’s blood sample has been sent for further testing Full Article Tamil Nadu
us Stop abuse of patent monopolies in rare diseases, say patient representatives and treatment activists By www.thehindu.com Published On :: Tue, 05 Nov 2024 19:17:18 +0530 They seek urgent intervention by government, courts, and lawmakers into the issue Full Article Health
us 'Sushant's death needs a CBI inquiry' By www.rediff.com Published On :: Wed, 08 Jul 2020 07:17:30 +0530 'This is not a fight just for Sushant, it is a fight against a system that suppresses genuine talent and forces them to take extreme steps.' Full Article Sushant Singh Rajput CBI Ashwiny Iyer Tiwari Shekhar Suman IMAGE Instagram Subhash K Jha Nitesh Tiwari Shuddh Desi Romance Adhyayan Bihar Chhichhore Patna
us EXCLUSIVE! Honey Irani: My Son Farhan Akhtar By www.rediff.com Published On :: Tue, 09 Jan 2024 15:43:35 +0530 'He was an extremely naughty child, always in trouble and creating trouble.''He wanted to fly a kite at night, and sometimes, bunk school.''When I insisted on sending him, we could get a call from school that he had fainted.' Full Article
us 'My struggle was because I'm a woman' By www.rediff.com Published On :: Tue, 30 Jan 2024 12:39:01 +0530 'You are constantly trying to get things made. You keep meeting people, knocking on their door. And time goes by.' Full Article
us 'I have no fear of failure because...' By www.rediff.com Published On :: Wed, 31 Jan 2024 10:44:01 +0530 '...when you hit rock bottom, you can't go any lower than that.'And I've been to rock bottom.''But that's what made me the actor I am today. I'm fearless.' Full Article
us 'Fireworks between Sushmita and me' By www.rediff.com Published On :: Mon, 05 Feb 2024 09:55:28 +0530 'People started noticing me again. OTT is a good platform for serious actors. In the olden days, unless you are the heroine, actors would have screen deaths. But now, there are so many good roles for women.' Full Article
us A Must Watch Film About Sexual Awakening By www.rediff.com Published On :: Mon, 05 Feb 2024 14:00:11 +0530 'I went to a school in Baroda, where if the boys harassed us, the teachers pulled the girls aside and said, "Oh, your skirts are too short".' 'They made us feel ashamed of having any sexual feelings or having bodies that were growing up to be a young women.' Full Article