b [ASAP] Design and Synthesis of Tetrazole- and Pyridine-Containing Itraconazole Analogs as Potent Angiogenesis Inhibitors By feedproxy.google.com Published On :: Mon, 13 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.9b00438 Full Article
b [ASAP] Potential Cancer Treatment by Agonists of the Stimulator of Interferon Genes By feedproxy.google.com Published On :: Mon, 13 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00117 Full Article
b [ASAP] Artemisinin Derivatives with Antimelanoma Activity Show Inhibitory Effect against Human DNA Topoisomerase 1 By feedproxy.google.com Published On :: Tue, 14 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00131 Full Article
b [ASAP] Complete Regression of Carcinoma via Combined C-RAF and EGFR Targeted Therapy By feedproxy.google.com Published On :: Tue, 14 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00159 Full Article
b [ASAP] Discovery of a Potent Dual Inhibitor of Wild-Type and Mutant Respiratory Syncytial Virus Fusion Proteins By feedproxy.google.com Published On :: Wed, 15 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00008 Full Article
b [ASAP] Sigma Receptor Ligands Carrying a Nitric Oxide Donor Nitrate Moiety: Synthesis, In Silico, and Biological Evaluation By feedproxy.google.com Published On :: Wed, 15 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.9b00661 Full Article
b [ASAP] Characterization of Specific <italic toggle="yes">N</italic>-a-Acetyltransferase 50 (Naa50) Inhibitors Identified Using a DNA Encoded Library By feedproxy.google.com Published On :: Wed, 15 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00029 Full Article
b [ASAP] Discovery of an Atropisomeric PI3Kß Selective Inhibitor through Optimization of the Hinge Binding Motif By feedproxy.google.com Published On :: Wed, 15 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00095 Full Article
b [ASAP] Can Drug Repositioning Work as a Systematical Business Model? By feedproxy.google.com Published On :: Fri, 17 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00122 Full Article
b [ASAP] Discovery of CPI-1612: A Potent, Selective, and Orally Bioavailable EP300/CBP Histone Acetyltransferase Inhibitor By feedproxy.google.com Published On :: Mon, 27 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00155 Full Article
b [ASAP] Development of Selective Steroid Inhibitors for the Glucose-6-phosphate Dehydrogenase from <italic toggle="yes">Trypanosoma cruzi</italic> By feedproxy.google.com Published On :: Wed, 29 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00106 Full Article
b [ASAP] P2Y<sub>14</sub> Receptor Antagonists Reverse Chronic Neuropathic Pain in a Mouse Model By feedproxy.google.com Published On :: Thu, 30 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00115 Full Article
b [ASAP] Discovery of Adamantane Carboxamides as Ebola Virus Cell Entry and Glycoprotein Inhibitors By feedproxy.google.com Published On :: Fri, 01 May 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00025 Full Article
b [ASAP] Benzoxazepine-Derived Selective, Orally Bioavailable Inhibitor of Human Acidic Mammalian Chitinase By feedproxy.google.com Published On :: Fri, 01 May 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00092 Full Article
b [ASAP] Scaffold Repurposing of in-House Chemical Library toward the Identification of New Casein Kinase 1 d Inhibitors By feedproxy.google.com Published On :: Mon, 04 May 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00028 Full Article
b [ASAP] Development of a Raltegravir-based Photoaffinity-Labeled Probe for Human Immunodeficiency Virus-1 Integrase Capture By feedproxy.google.com Published On :: Tue, 05 May 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00009 Full Article
b [ASAP] Substituted Azabicyclo[2.2.1]heptanes as Selective Orexin-1 Antagonists: Discovery of JNJ-54717793 By feedproxy.google.com Published On :: Tue, 05 May 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00085 Full Article
b [ASAP] Synthesis and Evaluation of <sup>11</sup>C- and <sup>18</sup>F-Labeled SOAT1 Inhibitors as Macrophage Foam Cell Imaging Agents By feedproxy.google.com Published On :: Wed, 06 May 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00127 Full Article
b [ASAP] Ligand Design for Cereblon Based Immunomodulatory Therapy By feedproxy.google.com Published On :: Fri, 08 May 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00214 Full Article
b Germany Facing Mass Blackouts Because The Wind And Solar Won’t Cooperate By latestsolarnews.com Published On :: Sat, 04 Mar 2017 19:59:09 +0000 Germany’s energy network nearly broken down in January because of poor execution from wind turbines and sun based boards, as indicated by information from a noteworthy exchange union. Wind and sunlight based power plants failed to meet expectations in January, 2017, as a result of shady climate with almost no wind, setting the phase for … The post Germany Facing Mass Blackouts Because The Wind And Solar Won’t Cooperate appeared first on LatestSolarNews. Full Article News
b 4 Benefits Of Solar LED Lights For Parking Lots By latestsolarnews.com Published On :: Sun, 08 Jul 2018 21:32:34 +0000 The future is solar LED lights. You will see them in the parking lots and other large areas around a city. They are cheap and save a good deal of money on electricity bills. Nowadays, the majority of parking lots feature the conventional lights that get their power from the grid. These products are not … The post 4 Benefits Of Solar LED Lights For Parking Lots appeared first on LatestSolarNews. Full Article Power Generation
b India is planning to achieve 50 GW of prodction from renewbale energy by 2028 By latestsolarnews.com Published On :: Tue, 08 Jan 2019 10:08:19 +0000 India is planning to achieve 50 gigawatt (GW) of production from renewable energy by 2028, in order to get to its goal of 40 per cent of electricity generation from non-fossil fuels by 2030, Ministry of New and Renewable Energy secretary, Anand Kumar said at the India-Norway Business Summit 2019 in New Delhi. Of this … The post India is planning to achieve 50 GW of prodction from renewbale energy by 2028 appeared first on LatestSolarNews. Full Article News india solar energy india
b A BEM syntax with UX in mind By simurai.com Published On :: Thu, 24 Oct 2013 00:00:00 +0000 At some point, while working on the MontageJS framework, the question came up what CSS naming convention we should start using. After a long discussion we settled on using the BEM methodology, but changed the syntax a bit. To keep this post short, I won’t go into detail why using BEM is a good idea, but rather explain why we chose a different syntax. Here some examples: .digit-Progress /* org-Component */ .digit-Progress-bar /* org-Component-childElement */ .digit-Progress--small /* org-Component--variation */ Note: The org- (digit-) prefix is used as a name-space so it wouldn’t conflict with other packages/libraries/frameworks. Now let’s take a look at the reasons for choosing such a syntax. Hyphens (-) The main reason why we’re using a hyphen (-) instead of underscores (_), has to do with the fact that their behavior is different when double-clicking to select text. Try for yourself: component__element /* underscores */ component-element /* hyphen */ See how when you’re using underscores it selects the part before and after, in this case the whole component__element. But with hyphens it let’s you select only the part you double-clicked. component OR element. This let’s you quickly edit only the parts you want: camelCase Now, what if the component or child element consists of multiple words? We could use underscores like component_name-element_name. It would still be double-clickable, but readability suffers since it’s harder to see what belongs together. Better to use camelCase which groups each part visually: componentName-elementName. MainComponent OK, I think we’re getting closer. As a last rule, for the “main” component we use PascalCase. The reason for it is to add emphasis and make it easier to distinguish the main component from a child element. Also when using a namespace, the component moves to the second position, which makes it even more important to have it stick out: org-Component-childElement –variation We kept the more commonly used double hyphens (–) for variations. digit-Progress--small. It makes sense, because it pulls the variation (–small) visually more apart and makes it look like it’s something “different” than the default component. So that’s about it. For more details about this naming convention, take a look at the SUIT framework, which also started to use the same syntax and documented it really well. In the end, whatever Shade of BEM you choose to cook with probably depends on your personal taste, but thinking about a great UX by improving usability and readability won’t hurt either. Full Article
b Back to the :roots By simurai.com Published On :: Wed, 09 Sep 2015 00:00:00 +0000 The cascade in CSS is a curse and blessing at the same time. It usually works quite well, but there are issues that let people get all worked up and ask the question Do We Even Need CSS Anymore. I can somewhat relate to that - but I also think it’s not the cascade alone and also about fighting specificity. Not running into issues with specificity is hard. Almost as hard as pronouncing that word. In this post I’ll try to show a few ways how you can make the cascade be your friend and maybe reduce the need of overriding and thus encounter less fighting with specificity. Tip 1: For every CSS property that you write, try to move it up the tree as far as possible. In other words: Back to the :root. For example, our site has a side bar and we want to add a short bio to it. The markup might look something like this: <body> <main class=“Posts”> <aside class=“SideBar”> <nav class=“Nav”> <p class=“Bio”> And the CSS: .Bio { font-size: .8em; line-height: 1.5; color: #888; } That would work. But if we look at the Nav that is already in the SideBar, chances are good that some of the styles are the same. In our case it’s font-size and color. So let’s remove those properties from Nav and Bio and add it to the shared parent element, the SideBar. .SideBar { font-size: .8em; color: #888; } And as it turns out, that line-height: 1.5; is already defined for our Posts. So since it seems that the whole page uses the same line-height, let’s remove it from the Bio and Post elements and move it all up to the root node. :root { line-height: 1.5; } This probably sounds like common sense, but often it’s tempting to just style your new thing without even looking if some of the sibling elements define the same thing. This also happens when you copy&paste styles from another section or when pasting some snippets you found online. It might take a bit more time to refactor and seems scary, but it should keep our CSS in a healthier state. Style the branches, not each leaf Tip 2: Style certain properties always as a combo. A good example is the color and background-color combo. Unless you make only small tweaks, it’s probably a good idea to always change them together. When adding a background color to an element, it might not contain any text, but probably some child will. Therefore if we set foreground and background color together, we can always be sure we won’t run into any legibility and contrast issues. Also, next time we change a background color, we don’t have to hunt for all the text colors that need to be changed too, it’s right there in the same place. Screenshot from Colorable Tip 3: Use “dynamic” values, such as currentColor and ems. Sometimes it might make sense to use the text color for other properties. Like for border, box-shadow or for the fill of SVG icons. Instead of defining them directly you can use currentColor and it will be the same the color property. And since color inherits by default, you might can change it in only one place. Similarly ems are mapped to font-size allowing you to scale everything by just changing the :root font size. Here a few more details on currentColor and EMs. Tip 4: Override UA Styles to inherit from its parents. Form controls like buttons, inputs get styled by the browser in a certain way. Overriding them with inherit makes them adapt to your own styles. button, input, select, textarea { color: inherit; font-family: inherit; font-style: inherit; font-weight: inherit; } The example above is taken from sanitize.css. normalize.css does the same, so if you use them, you’re already covered. You can also try to restyle other inputs like a range slider, radio, checkbox etc. And as seen above, by using currentColor, make them automatically match the color property. And maybe move them from a light into a dark theme without changing anything. Conclusion That’s all nice stuff, but who is it for? Well, of course it can’t be forced upon every situation. I would say small and simple web sites benefit the most. But even when using a preprocessor, it might not hurt if it reduces the amount of CSS that gets output or when a few variables aren’t even needed. Also it seems suited for the “single purpose class” approach like Tachyons. It might reduce complexity and the amount of classes that are needed. Another interesting thing could be the upcoming custom properties a.k.a. CSS variables. Unlike variables in preprocessors, when overriding a custom property, it will only affect the current selector scope. So in a sense they will be “cascading variables”. But I still have to try that out and see how it works in practice. ps. It is possible that this post is inspired by this tweet. Full Article
b The Latest Research for Web Designers, April 2020 By www.webdesignerdepot.com Published On :: Mon, 27 Apr 2020 10:45:10 +0000 Although life hasn’t returned to normal yet, the web design and marketing space doesn’t seem to have been too badly disrupted — at least not with all the new research and surveys floating around. And thank goodness for that. If we can maintain some semblance of normalcy, I think we’ll all get through this crisis in good shape. Full Article Business & Tech cybersecurity design research ecommerce marketing technical seo web design facts web design research
b Email Personalization: Your Secret To Better Engagement By www.webdesignerdepot.com Published On :: Wed, 29 Apr 2020 10:45:54 +0000 One of the struggles that marketers face is how to send the right message at exactly the right time to target people in a way that will appeal to them. To solve the problem, businesses need to get themselves acquainted with new technologies and the power of personalization. In the past few years, digital marketing […] Full Article Search & Marketing customer funnel email engagement email marketing marketing tips personalized email
b 8 Best CMS for 2020 By www.webdesignerdepot.com Published On :: Fri, 01 May 2020 10:45:36 +0000 Content Management Systems are arguably the internet’s most powerful web development tool. In a rapidly growing market where every business under the sun requires a website that is not only fully functioning, but optimised, easy to update regularly, and implement the latest features, the right CMS is important. As a web developer it can be […] Full Article Tools & Resources Concrete5 Craft Flextype joomla Magnolia MotoCMS Umbraco Vapid
b Thanks to Covid-19, Website Accessibility Has Never Been More Important By www.webdesignerdepot.com Published On :: Thu, 07 May 2020 10:45:59 +0000 The first global pandemic of the digital era is upon us. We’re living in unprecedented and uncomfortable times. For our senior citizens, these past several weeks have been particularly discomforting. According to the CDC, men and women over the age of 65 are significantly more likely to develop complications from COVID-19. As we seek to […] Full Article Interactive Design a11y design for seniors older web users web design for elderly website accessibility
b Hockey | HI asks for bids to host various Nationals By www.thehindu.com Published On :: Tue, 05 May 2020 22:53:48 +0530 State units can take part across age-groups Full Article Hockey
b The matter of photography in the Americas / Natalia Brizuela and Jodi Roberts ; with contributions by Lisa Blackmore, Amy Sara Carroll, Marianela D'Aprile, María Fernanda Domínguez, Heloisa Espada, Rachel Price, Diana Ruiz, Tatiane Santa Ro By library.mit.edu Published On :: Sun, 16 Feb 2020 06:00:01 EST Rotch Library - TR184.B75 2018 Full Article
b How art can be thought: a handbook for change / Allan deSouza By library.mit.edu Published On :: Sun, 16 Feb 2020 06:00:01 EST Rotch Library - N7425.D459 2018 Full Article
b Library of light: encounters with artists and designers / Jo Joelson By library.mit.edu Published On :: Sun, 16 Feb 2020 06:00:01 EST Rotch Library - N8219.L5 J64 2019 Full Article
b Huguette Caland / edited by Anne Barlow, Sara Matson and Giles Jackson ; texts by Anne Barlow, Brigitte Caland and Negar Azimi By library.mit.edu Published On :: Sun, 16 Feb 2020 06:00:01 EST Rotch Library - N6537.C329 A4 2019 Full Article
b Legacy of the masters: painting and calligraphy of the Islamic world from the Shavleyan family collection / Will Kwiatkowski ; with contributions by John Seyller By library.mit.edu Published On :: Sun, 16 Feb 2020 06:00:01 EST Rotch Library - N6260.K87 2019 Full Article
b Usṭūrahʹhā va namādʹhā-yi āyinī dar nigārahʹhā-yi Saqānifārʹhā-yi Māzandarān / taʼlīf va gurdʹāvarī-i Muṣṭafá Rustamī, Fāṭimah Bābājānʹtabār Nashlī By library.mit.edu Published On :: Sun, 16 Feb 2020 06:00:01 EST Rotch Library - N7280.R888 2018 Full Article
b For your pleasure: Johannes Brus, photoworks and sculptures / with an essay by Clément Chéroux By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N6888.B745 A4 2018 Full Article
b Bauhaus imaginista: a school in the world / edited by Marion von Osten and Grant Watson By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N332.G33 B42724 2019 Full Article
b Anna Maria Maiolino, Entre pausas / texts by Anna Maria Maiolino, Tania Rivera and Randy Kennedy By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - NC200.M27 A4 2018 Full Article
b Leonardo da Vinci: nature and architecture / edited by Constance Moffatt, Sara Taglialagamba By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N6923.L33 M64 2019 Full Article
b Djordje Ozbolt: regaining memory loss / exhibition curator, Nicoletta Lambertucci By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N6488.I8 V433 2019 Y8 Full Article
b El nombre de un país / Mariana Telleria ; curadora, Florencia Battiti By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N6488.I8 V433 2019 A7 Full Article
b New design, neoplasticism: Nieuwe beelding / Piet Mondrian ; English translation by Harry Holtzman and Martin S. James By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N6948.5.D42 M6613 2019 Full Article
b Inventing Boston: design, production, and consumption / Edward S. Cooke, Jr By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - NK838.B67 C66 2019 Full Article
b Arnaud Vasseux: pièces non balayées. By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - NB553.V37 A4 2018 Full Article
b After illusion: Baʻad tūham / Zahrah al-Gamdi By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N6488.I8 V433 2019 S33 Full Article
b Gordon Parks: the new tide, early work, 1940-1950 / Philip Brookman ; with essays by Maurice Berger, Sarah Lewis, Richard J. Powell, Deborah Willis ; series editor, Peter W. Kunhardt, Jr By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - TR647.P37 2018 Full Article
b Heirloom / Larissa Sansour ; text by Nat Muller By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N6488.I8 V433 2019 D4 Full Article
b Art for people's sake: artists and community in Black Chicago, 1965-1975 / Rebecca Zorach By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - NX512.3.A35 Z67 2019 Full Article
b I have forgotten the night / Joël Andrianomearisoa ; curated by Rina Ralay Ranaivo and Emmanuel Daydé By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N6488.I8 V433 2019 M28 Full Article
b Herbst im paradies: The autumn of paradise / Jean-Luc Mylayne By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - TR729.B5 H47 2018 Full Article