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Broadening the substrate range of serine palmitoyltransferase by protein engineering and applications to 3-keto-dihydrosphingosine analogs

Catal. Sci. Technol., 2024, 14,6600-6608
DOI: 10.1039/D4CY01019A, Paper
Hyunjun Choe, Minsun Cha, Ahram Kim, Jon D. Stewart
Introducing an additional mutation at position 73 dramatically increases the substrate range, allowing access to a wide variety of sphingolipid analogs.
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Boron–pyridine nitrogen cooperative catalytic conversion of carbon dioxide and epoxides to cyclic carbonates

Catal. Sci. Technol., 2024, 14,6692-6700
DOI: 10.1039/D4CY01052C, Paper
Yu-Hui Luo, Sheng Tao, Fei Chen, Zhi-Hong Du, Hao Zhang, Min Li, Ning Liu
A type of N-heterocyclic carbene (NHC)-diboron adduct in combination with tetrabutylammonium iodide (TBAI) was used as a catalyst for the synthesis of cyclic carbonates from CO2 with epoxides.
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Unspecific peroxygenase immobilization in 3D-printed microfluidics: towards tailor-made screening platforms

Catal. Sci. Technol., 2024, 14,6496-6502
DOI: 10.1039/D4CY00869C, Communication
Elena Gkantzou, Theofilia Koulopoulou, Hannah Brass, David Schönauer, Anton Glieder, Selin Kara
In the context of empowering biocatalysis, an easy-to-develop, reproducible, and easy-to-scale biocatalytic system is demonstrated as a microfluidic screening platform.
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Correction: 1D Zn(II)/2D Cu(I) halogen pyridyl coordination polymers. Band gap engineering by DFT for predicting more efficient photocatalysts in water treatment

Catal. Sci. Technol., 2024, 14,6720-6720
DOI: 10.1039/D4CY90084G, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Andrea García-Hernán, Fernando Aguilar-Galindo, Oscar Castillo, Pilar Amo-Ochoa
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Phenol Hydroxyl-Modified Imine-Based Covalent organic framework for enhanced solar-driven generation of H2O2 via Hydrogen Bonds

Catal. Sci. Technol., 2024, Accepted Manuscript
DOI: 10.1039/D4CY01096E, Paper
Lang Chen, Song Qin, Jiahui Hang, Bo Chen, Jinyang Kang, yang zhao, Shan-Yong Chen, Yongdong Jin, Hongjian Yan, Yuanhua Wang, Xia Chuanqin
Photosynthesis of H2O2 have been considered an eco-friendly strategy. However, the concentration of H2O2 in reported studies is far from industrial requirement. Herein, we present a strategy by employing phenolic...
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Material design of biodegradable primary batteries: boosting operating voltage by substituting the hydrogen evolution reaction at the cathode

Nanoscale, 2024, 16,20027-20036
DOI: 10.1039/D4NR03321C, Minireview
Shunsuke Yamada, Takashi Honda
This review highlights recent progress in increasing the operating voltage of biodegradable primary batteries by suppressing or substituting the hydrogen evolution reaction at the cathode with alternative redox reaction.
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An eco-friendly polycaprolactone/graphite composite as a robust freestanding electrode platform for supercapacitive energy storage

Nanoscale, 2024, 16,20155-20167
DOI: 10.1039/D4NR03113J, Paper
Rajeev Gupta, Monika Singhal
A novel eco-friendly composite electrode/current collector made from polycaprolactone and graphite filler offers bulk conductivity, is freestanding, cost-effective, and shows supercapacitive energy storage potential with electrodeposited polyaniline.
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Nanoscopic visualization of microgel-immobilized cytochrome P450 enzymes and their local activity

Nanoscale, 2024, 16,20194-20201
DOI: 10.1039/D4NR03435J, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Lukas Schubert, Chiara Nenninger, Maximilian Nöth, Thomke Belthle, Robert Dirk de Lange, Andrij Pich, Ulrich Schwaneberg, Dominik Wöll
The distribution and local catalytic activity of Cytochrome P450 enzymes immobilized in microgels by electrostatic interaction has been determined with a combination of in situ super-resolution fluorescence microscopy experiments.
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Preparation and application of high thermal conductivity phase change microcapsules with fluorescence characteristics based on a ZnWO4 shell

Nanoscale, 2024, 16,20331-20341
DOI: 10.1039/D4NR02691H, Paper
H. Cheng, B. Tang, H. Y. Bao, F. Shan, C. X. Lu
This method produces microcapsules that possess a high thermal rate and good UV absorption and fluorescence properties, making them suitable for use in fluorescent buildings, textiles, coatings, and other applications.
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Active site engineering of intermetallic nanoparticles by the vapour–solid synthesis: carbon black supported nickel tellurides for hydrogen evolution

Nanoscale, 2024, 16,20168-20181
DOI: 10.1039/D4NR03397C, Paper
Open Access
Daniel Garstenauer, Patrick Guggenberger, Ondřej Zobač, Franz Jirsa, Klaus W. Richter
The intermetallic phases Ni3Te2, NiTe, NiTe2−x & NiTe2 were synthesized as carbon-black supported nanoparticles using the vapour–solid synthesis approach and were characterized for their performance in electrocatalytic hydrogen evolution.
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Synergistic effect of ROS-generating polydopamine on drug-induced bone tissue regeneration

Nanoscale, 2024, 16,20118-20130
DOI: 10.1039/D4NR02887B, Paper
Hyeju Han, Bongkyun Kang, Shazid Md. Sharker, Tabassum Binte Kashem, Yuejin Kim, Jeehee Lee, Minok Park, Eunjeong Kim, YunJae Jung, Jinkyu Lim, Seungwon Ryu, Kyueui Lee
The combination of PDA NPs and 1,4-DPCA leads to a synergistic effect that enhances bone tissue regeneration in vivo.
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Nano-sized metal oxide fertilizers for sustainable agriculture: balancing benefits, risks, and risk management strategies

Nanoscale, 2024, 16,19998-20026
DOI: 10.1039/D4NR01354A, Review Article
Raja Muthuramalingam Thangavelu, Washington Luis da Silva, Nubia Zuverza-Mena, Christian O. Dimkpa, Jason C. White
This critical review comprehensively analyses nano-sized metal oxide fertilizers (NMOFs) and their transformative potential in sustainable agriculture.
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Folic acid-targeted redox responsive polylactic acid-based nanoparticles co-delivering pirarubicin and salinomycin suppress breast cancer tumor growth in vivo

Nanoscale, 2024, 16,20131-20146
DOI: 10.1039/D4NR02365J, Paper
Priya Gupta, Ankushi Bansal, Harshdeep Kaur, Mohd Anees, Neetu Singh, Harpal Singh
Schematic illustration of design, administration, and mechanism of action of Pira/Sal dual-loaded FA-conjugated redox responsive [S-(PLA-b-PEG-CONH)]2 block copolymeric nanoparticles.
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“Sergeants-and-soldiers” principle in the synthesis of intrinsically chiral Au13 clusters

Nanoscale, 2024, Advance Article
DOI: 10.1039/D4NR03810J, Paper
Open Access
Katsuya Mutoh, Sonomi Kawakita, Teppei Yahagi, Takuya Nakashima
Single chiral ligand coordination effectively deracemizes intrinsically chiral Au13 clusters with binary mixed ligands of chiral and achiral diphosphines.
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Oxygen electrode catalysis in N-doped graphene: the role of nitrogen coordination and solvation effects

Nanoscale, 2024, Advance Article
DOI: 10.1039/D4NR03645J, Paper
Junxian Liu, Yun Wang, Yuantong Gu, Liangzhi Kou
The significance of explicit solvents in describing the adsorption behaviors of ORR/OER intermediates is emphasized. A higher HOMO level of active sites enhances binding to oxygen intermediates, thereby improving ORR/OER activity.
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Retarding anion exchanges in lead halide perovskite nanocrystals by ligand immobilization

Nanoscale, 2024, Advance Article
DOI: 10.1039/D4NR03241A, Paper
Gauri Sharma, Radha Rathod, Pralay K. Santra
Plasma treatment causes the crosslinking of passivating molecules around CsPbX3 (X = Cl, Br, I) perovskite nanocrystals (PNCs), which retards the anion exchanges.
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Macroscopic chiral symmetry breaking in gelation of Fmoc-amino acids: homochiral selective secondary nucleation promoted by the choice of solvent or stirring

Nanoscale, 2024, Advance Article
DOI: 10.1039/D4NR04011B, Communication
Kentaro Tashiro
Homochiral selective secondary nucleation, promoted by the choice of solvent or stirring, was suggested as the key process for the emergence of macroscopic chiral symmetry breaking in the gelation of Fmoc amino acids.
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Ab-initio Calculations of Vibrational Fingerprints in the Photoluminescence of Graphene Quantum Dots

Nanoscale, 2024, Accepted Manuscript
DOI: 10.1039/D4NR02458C, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Ruoyu Wu, Peng Han, Tobias Dittmann, Fu-He Wang, Yan Zhang, Gabriel Bester
We use a computational method based on ab initio (constrained) density functional theory to obtain the photoluminescence spectrum of graphene quantum dots with up to 240 carbon atoms, including the...
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Enhanced antifungal activity of siRNA-loaded anionic liposomes against the human pathogenic fungus Aspergillus fumigatus

Nanoscale, 2024, Advance Article
DOI: 10.1039/D4NR03225J, Communication
Open Access
Yidong Yu, Theresa Vogel, Sina Hirsch, Jürgen Groll, Krystyna Albrecht, Andreas Beilhack
Application of anionic liposomes co-loaded with amphotericin B and siRNA demonstrates a temporary antifungal effect lasting 3–4 days, highlighting their therapeutic potential.
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DON encapsulated carbon dot–vesicle conjugate in therapeutic intervention of lung adenocarcinoma by dual targeting of CD44 and SLC1A5

Nanoscale, 2024, Advance Article
DOI: 10.1039/D4NR00426D, Paper
Afreen Zaman, Aparajita Ghosh, Anup Kumar Ghosh, Prasanta Kumar Das
HACD–TMAV, a carbon dot–vesicle conjugate, selectively delivered glutamine inhibitor DON to CD44-enriched cancer cells, inducing ROS triggered apoptosis by dual targeting CD44 and SLC1A5 through downregulation of PI3K/AKT/mTOR signalling cascade.
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Current progress and frontiers in three-dimensional macroporous carbon-based aerogels for electromagnetic wave absorption: a review

Nanoscale, 2024, Advance Article
DOI: 10.1039/D4NR03738C, Review Article
Han Ding, Bo Hu, Yu Wang, Yunchen Du
This article provides a timely review on the construction of three-dimensional macroporous carbon-based aerogels and their application in the field of electromagnetic absorption.
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The interaction of glycogen nanoparticles with human blood

Nanoscale, 2024, Advance Article
DOI: 10.1039/D4NR03034F, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Nadiia Davydiuk, Vaidehi Londhe, Manfred F. Maitz, Carsten Werner, Andreas Fery, Quinn A. Besford
Glycogen nanoparticles are emerging biomaterials for theranostic applications. This study investigates the interactions of glycogen nanoparticles from different sources with human blood, finding that all are hemocompatible nanomaterials.
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Tailored peptide nanomaterials for receptor targeted prostate cancer imaging

Nanoscale, 2024, Advance Article
DOI: 10.1039/D4NR03273J, Paper
Fátima Santillán, Carlie L. Charron, Betty C. Galarreta, Leonard G. Luyt
This study reports on a cancer targeted nanomaterial created from cyclic octapeptides that is tailored for the optical imaging of prostate cancer. The strategy focuses on the co-assembly of four specific templates into cyclic peptide nanotubes.
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Preceramic polymer hybridized phenolic aerogels and the derived ZrC/SiC/C ceramic aerogels with ultrafine nanocrystallines

Nanoscale, 2024, Accepted Manuscript
DOI: 10.1039/D4NR03470H, Paper
Ding Nie, Hangyu Zhong, Hongli Hu, Zhenhua Luo, Boxing Zhang
Phenolic and carbon aerogels have important applications for thermal insulation and ablative resistance materials in aerospace areas. However, their antioxidant ability in long-term and high-temperature aerobic environments is facing serious...
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Biomass-derived substrates hydrogenation over Rhodium Nanoparticles Supported on Functionalized Mesoporous Silica

Nanoscale, 2024, Accepted Manuscript
DOI: 10.1039/D4NR02579B, Paper
Open Access
Israel Tonatiuh Pulido-Díaz, Draco Martínez, Karla Patricia Salas-Martin, Benjamín Portales-Martínez, Dominique Agustin, Antonio Reina, Itzel Guerrero Ríos
The use of supported rhodium nanoparticles (RhNPs) is gaining attention due to the drive for better catalyst performance and sustainability. Silica-based supports are promising for RhNP immobilization because of their...
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Nanoparticle’s shape is the game-changer for blood-brain barrier crossing and delivering through tunneling nanotubes among glioblastoma cells.

Nanoscale, 2024, Accepted Manuscript
DOI: 10.1039/D4NR03174A, Paper
Open Access
Giulia Sierri, Ines Saenz-de-Santa-Maria, Antonio Renda, Marcus Koch, Patrizia Sommi, Umberto Anselmi-Tamburini, Mario Mauri, Alessia D'Aloia, Michela Ceriani, Domenico Salerno, FRANCESCO MANTEGAZZA, Chiara Zurzolo, Francesca Re
Tunneling Nanotubes (TNTs) are thin, dynamic, long membrane protrusions that allow the intercellular exchanges of signal clues, molecules and organelles. The presence of TNTs and their involvement as drug delivery...
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Synthesis, Characterization, Genotoxicity Assessment and Antibacterial Applications of Zanthoxylum armatum Silver Nanoparticles (ZASNP) with Antibiotic Efficacy Enhancement Potential

Nanoscale, 2024, Accepted Manuscript
DOI: 10.1039/D4NR03608E, Paper
Open Access
Nikita Quadri, Manjunath M. Setty, Anshumali Awasthi, Usha Yogendra Nayak, Minakshi Singh, Sharad Sharma
The study aimed to develop alternative antibacterial treatments by combining traditional herbal knowledge with modern nanotechnology. This approach targets multiple bacterial strains, combats antibiotic resistance, and offers solutions for treating...
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Low Volume Shrinkage Alkaline Degradable UV Nanoimprint Lithography Resists Based on Acrylic Anhydride

Nanoscale, 2024, Accepted Manuscript
DOI: 10.1039/D4NR03291H, Paper
Chuan Zhe Zhao, Ya-Juan Cai, Yi-Xing Sun, Ya-Ge Wu, Kexiao Sang, Ting Yue, Zihao Yang, Jinggang Gai
The shrinkage phenomenon of UV-NIL resist during photocuring is still regarded as an important problem hindering the wide application of UV-NIL technology. We designed four degradable UV-NIL resists with low...
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Ultra-efficient delivery of CRISPR/Cas9 using ionic liquid conjugated polymers for genome editing-based tumor therapy

Biomater. Sci., 2024, 12,1716-1725
DOI: 10.1039/D3BM01981K, Paper
Zhongming Huang, Tongren Yang, Jie Yu, Yijian Gao, Yuhua Weng, Yuanyu Huang, Shengliang Li
Through molecular screening, ionic liquid-conjugated polymers (IL-CPs) are developed for highly efficient delivery of CRISPR/Cas9 system, which demonstrated high-performance genome editing-based tumor therapy.
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Applications of peptide-based nanomaterials in targeting cancer therapy

Biomater. Sci., 2024, 12,1630-1642
DOI: 10.1039/D3BM02026F, Review Article
Beilei Sun, Limin Zhang, Mengzhen Li, Xin Wang, Weizhi Wang
To meet the precise diagnosis and treatment as well as reduce systemic toxicity and side effects, self-assembled peptides are applied to the targeting therapy, including targeting theranostics, nanocarrier delivery, immunotherapy, and combination therapy.
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Efficient healing of diabetic wounds by MSC-EV-7A composite hydrogel via suppression of inflammation and enhancement of angiogenesis

Biomater. Sci., 2024, 12,1750-1760
DOI: 10.1039/D3BM01904G, Paper
Xinyi Long, Qian Yuan, Rui Tian, Wanting Zhang, Lang Liu, Minghui Yang, Xin Yuan, Zhujie Deng, Quanjiang Li, Ronghui Sun, Yuyi Kang, Yingying Peng, Xiubin Kuang, Lingfang Zeng, Zhengqiang Yuan
An alginate hydrogel loaded with mesenchymal stem-cell-derived extracellular vesicles (EVs) and a 7-amino-acid peptide (7A) constitutes a novel dressing for efficient healing of diabetic wounds with anti-inflammation and pro-angiogenesis mechanisms.
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Comparative analysis of supercritical fluid-based and chemical-based decellularization techniques for nerve tissue regeneration

Biomater. Sci., 2024, 12,1847-1863
DOI: 10.1039/D3BM02072J, Paper
Open Access
Beom-Seok Kim, Jeong-Uk Kim, Jae Woo Lee, Kyung Min Ryu, Rachel H. Koh, Kyoung-Ha So, Nathaniel S. Hwang
The supercritical (SC) fluid-based method were utilized for nerve tissue decellualrization. In vitrovivo assessments underscore its potential for advanced tissue engineering and regenerative applications.
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Gelatine–collagen photo-crosslinkable 3D matrixes for skin regeneration

Biomater. Sci., 2024, 12,1738-1749
DOI: 10.1039/D3BM01849K, Paper
Open Access
Gauthier Menassol, Boudewijn van der Sanden, Laetitia Gredy, Capucine Arnol, Thibaut Divoux, Donald K. Martin, Olivier Stephan
Immediate care of skin wounds and burns is essential to repair this mechanical and chemical barrier to infections.
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Sorafenib and tetrakis (4-carboxyphenyl) porphyrin assembled nanoparticles for synergistic targeted chemotherapy and sonodynamic therapy of hepatocellular carcinoma

Biomater. Sci., 2024, 12,1864-1870
DOI: 10.1039/D3BM01994B, Paper
Yongzhi Chen, Qiuxia Tan, Yuanyu Tang, E. Pang, Rui Peng, Minhuan Lan, Dousheng Bai
Hepatocellular carcinoma (HCC) is characterized by a high degree of malignancy and mortality.
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Extracellular vesicles produced by 3D cultured MSCs promote wound healing by regulating macrophage activation through ANXA1

Biomater. Sci., 2024, 12,1761-1770
DOI: 10.1039/D3BM02035E, Paper
Hao Deng, Yuheng Jiang, Junhao Deng, Feifan Chang, Junyu Chen, Xinyu Sun, Dongliang Cheng, Zhongqi Wang, Ran Li, Jiang Liu, Yi Li, Licheng Zhang, Pengbin Yin
Extracellular vesicles (EVs) produced by 3D-cultured MSCs can modulate macrophage activation through ANXA1, thereby promoting wound healing.
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Dynamic monitoring of the fibrosis disease by a collagen targeting near infrared probe

Biomater. Sci., 2024, 12,1924-1931
DOI: 10.1039/D3BM01926H, Paper
Xiaoke Zhang, Qianwen Yang, Sensen Zhou, Cheng Li, Xiqun Jiang
A H2O2-sensitive macromolecular optical probe which can effectively bind to collagen was developed for real time noninvasive visualization of fibrotic tissues.
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Self-adjuvanted L-arginine-modified dextran-based nanogels for sustained local antigenic protein delivery to antigen-presenting cells and enhanced cellular and humoral immune responses

Biomater. Sci., 2024, 12,1771-1787
DOI: 10.1039/D3BM01150J, Paper
Jin Teng Chung, Mehrnoosh Rafiei, Ying Chau
Antigens are delivered in self-adjuvanted arginine-modified dextran-based nanogels to the dendritic cells in promoting antigen specific cellular immunity.
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Fibromodulin facilitates the osteogenic effect of Masquelet's induced membrane by inhibiting the TGF-β/SMAD signaling pathway

Biomater. Sci., 2024, 12,1898-1913
DOI: 10.1039/D3BM01665J, Paper
Kai Wang, Ming Zhou, Yuanshu Zhang, Yesheng Jin, Yuan Xue, Dong Mao, Yongjun Rui
Schematic illustration of the mechanism by which an IM promotes bone formation. FMOD secreted by the IM promotes osteogenesis of BMSCs and angiogenesis of HUVECs by inhibiting the TGF-β/SMAD signaling pathway, thus facilitating bone formation.
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Janus hydrogels: merging boundaries in tissue engineering for enhanced biomaterials and regenerative therapies

Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D3BM01875J, Review Article
Yingxue Jiang, Chenhui Zhu, Xiaoxuan Ma, Daidi Fan
In recent years, the design and synthesis of Janus hydrogels have advanced significantly, overcoming single-performance material limitations and broadening applications in tissue engineering and regenerative medicine.
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Tissue-specific gelatin bioink as a rheology modifier for high printability and adjustable tissue properties

Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D3BM02111D, Paper
Open Access
Hohyeon Han, Minji Kim, Uijung Yong, Yeonggwon Jo, Yoo-mi Choi, Hye Jin Kim, Dong Gyu Hwang, Dayoon Kang, Jinah Jang
This study introduces gelatinized dECM, a tissue-specific rheological modifier, enabling high-resolution printing of flexible tissue constructs with enhanced resilience.
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Multifunctional antibacterial hydrogels for chronic wound management

Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM00155A, Review Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Yungang Hu, Lu Yu, Qiang Dai, Xiaohua Hu, Yuming Shen
Due to their distinctive physical and chemical properties as well as their biological functionalities, multifunctional antibacterial hydrogels possess significant advantages in the treatment of chronic wounds.
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A mitochondria-targeting heptamethine cyanine-chlorambucil formulated polymeric nanoparticle to potentiate native tumor chemotherapeutic efficacy

Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM00003J, Paper
Jing Liu, Jie Zhang, Yongteng Zhang, Wei Wei, Meixiao Zhan, Zhiren Zhang, Bing Liu, Xianglong Hu, Weiling He
Facile conjugation of chlorambucil with IR775 chloride can afford IR775-Cbl with mitochondria-targeting potency for tumor cells, exhibiting distinct “1 + 1 > 2” tumor inhibition.
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Correction: ECM-based bioadhesive hydrogel for sutureless repair of deep anterior corneal defects

Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM90027H, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Safieh Boroumand, Faraz Sigaroodi, Seyed Mohsen Ahmadi Tafti, Keyvan Khoshmaram, Masoud Soleimani, Mohammad-Mehdi Khani
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Exosomes encapsulated in hydrogels for effective central nervous system drug delivery

Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D3BM01055D, Review Article
Ziba Zakeri, Morteza Heiderzadeh, Azra Kocaarslan, Ecem Metin, Seyed Nasir Hosseini Karimi, Sepideh Saghati, Atay Vural, Göktuğ Akyoldaş, Kemal Baysal, Yusuf Yağcı, Yasemin Gürsoy-Özdemir, Savaş Taşoğlu, Reza Rahbarghazi, Emel Sokullu
The targeted delivery of pharmacologically active molecules, metabolites, and growth factors to the brain parenchyma has become one of the major challenges following the onset of neurodegeneration and pathological conditions.
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Macrophage membrane-camouflaged nanoclusters of ultrasmall iron oxide nanoparticles for precision glioma theranostics

Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM00357H, Paper
Bin Zhang, Rui Yang, Hongwei Yu, Yamin Peng, Haoyu Huang, Meera Moydeen Abdul Hameed, Han Wang, Guixiang Zhang, Mohamed EL-Newehy, Mingwu Shen, Xiangyang Shi, Shaojun Peng
Macrophage membrane-camouflaged nanoclusters of ultrasmall iron oxide nanoparticles can be developed to cross the blood–brain barrier for magnetic resonance imaging and chemo/chemodynamic therapy.
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Comparison study of surface-initiated hydrogel coatings with distinct side-chains for improving biocompatibility of polymeric heart valves

Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM00158C, Paper
Yiduo Chen, Yirong Guo, Xinyi Li, Yanchen Chen, Jiarong Wang, Honglin Qian, Jing Wang, Youxiang Wang, Xinyang Hu, Jian'an Wang, Jian Ji
Three surface-initiated hydrogel coatings (pMPC, pAMPS, pHEMA) are constructed on polymeric heart valves. The zwitterionic pMPC coating displays optimal performances, including durable anti-coagulation, anti-inflammation, and anti-calcification.
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Microgels for bioprinting: recent advancements and challenges

Biomater. Sci., 2024, 12,1950-1964
DOI: 10.1039/D3BM01733H, Review Article
Mingjun Xie, Ji Wang, Sufan Wu, Sheng Yan, Yong He
This review introduces different methods used to generate microgels and the microgel-based bioink for bioprinting. Besides, the further tendency of microgel development in future is predicted.
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ABCD of IA: A multi-scale agent-based model of T cell activation in inflammatory arthritis

Biomater. Sci., 2024, 12,2041-2056
DOI: 10.1039/D3BM01674A, Paper
David A. McBride, James S. Wang, Wade T. Johnson, Nunzio Bottini, Nisarg J. Shah
The study develops a computational framework to model factors that lead to the evolution of autoreactive T cells in inflammatory arthritis. The results provide a tool for planning immunomodulatory strategies focused on new disease-modifying agents.
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PET image-guided kidney injury theranostics enabled by a bipyramidal DNA framework

Biomater. Sci., 2024, 12,2086-2095
DOI: 10.1039/D3BM01575K, Paper
Open Access
Pinghui Li, Zhidie Huang, Xiaoyan Duan, Tao Wang, Shaowen Yang, Dawei Jiang, Jianbo Li
We constructed 68Ga-BDF and employed PET imaging to establish its pharmacokinetic model. BDF was eliminated from the body via the urinary system. We observed distinct imaging indicators in UUO and AKI mouse models. Furthermore, we observed the therapeutic effect of BDF on AKI.
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A nanoparticle reinforced microporous methacrylated silk fibroin hydrogel to promote bone regeneration

Biomater. Sci., 2024, 12,2121-2135
DOI: 10.1039/D3BM01901B, Paper
Ruideng Wang, Xi He, Zhengyang Chen, Shilong Su, Jinwu Bai, Haifeng Liu, Fang Zhou
A photo-crosslinked nanocomposite hydrogel was prepared by incorporating an osteo-inductive inorganic nanoparticle for endogenous bone regeneration.
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