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The chafing.…

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The Inlander is a community newspaper covering news, politics, events, happy hour, everything that's happening today, things to do on the weekend, in Spokane, Coeur d'Alene, the greater Inland Northwest and beyond.

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Novel indansulfamide derivatives or a pharmaceutically acceptable salt thereof such as N-[(1S)-2,2,5,7-tetrafluoro-2,3-dihydro-1H-inden-1-yl]sulfamide, N-[(1S)-2,2,4,7-tetrafluoro-2,3-dihydro-1H-inden-1-yl]sulfamide, (+)-N-(2,2,4,6,7-pentafluoro-2,3-dihydro-1H-inden-1-yl)sulfamide, have an action of improving Seizure Severity Index (Score) in mice kindling model. Thus the compounds or the salt thereof are expected as a drug for treating epilepsy.

Processing metadata includes storing, in a data storage system, a specification for each of multiple sources, each specification including information identifying one or more data elements of the corresponding source; and processing, in a data processing system coupled to the data storage system, data elements from the sources, including generating a set of rules for each source based on a corresponding one of the stored specifications, and matching data elements of different sources and determining a quality metric characterizing a given match between a first data element of a first source and a second data element of a second source according to the set of rules generated for the first source and the set of rules generated for the second source.

A computer-implemented method is provided for statistical data learning under privacy constraints. The method includes: receiving, by a processor, a plurality of pieces of statistical information relating to a statistical object and aggregating, by the processor, the plurality of pieces of statistical information so as to provide an estimation of the statistical object. Each piece of statistical information includes an uncertainty variable, the uncertainty variable being a value determined from a function having a predetermined mean. The number of pieces of statistical information aggregated is proportional to the reliability of the estimation of the statistical object.

A modeling framework for evaluating the impact of weather conditions on farming and harvest operations applies real-time, field-level weather data and forecasts of meteorological and climatological conditions together with user-provided and/or observed feedback of a present state of a harvest-related condition to agronomic models and to generate a plurality of harvest advisory outputs for precision agriculture. A harvest advisory model simulates and predicts the impacts of this weather information and user-provided and/or observed feedback in one or more physical, empirical, or artificial intelligence models of precision agriculture to analyze crops, plants, soils, and resulting agricultural commodities, and provides harvest advisory outputs to a diagnostic support tool for users to enhance farming and harvest decision-making, whether by providing pre-, post-, or in situ-harvest operations and crop analyzes.

The present disclosure involves systems, software, and computer-implemented methods for providing process intelligence by correlating events from multiple business process systems to a single business scenario using configurable correlation strategies. An example method includes identifying a raw event associated with a sending business process and a receiving business process, identifying a sending business process attribute associated with the sending business process and a receiving business process attribute associated with the receiving business process, determining a correlation strategy for associating the raw event with a business scenario instance, the determination based at least in part on the sending business process attribute and the receiving business process attribute, and generating a visibility scenario event from the raw event according to the correlation strategy, the visibility scenario event associated with the business scenario instance.

Embodiments of the invention provide systems and methods for analyzing sequential data. The sequential data can comprise a sequence of data points arranged in a particular order and thus representing a sequence. A number of such sequences can be analyzed, for example, to identify patterns or commonalities within the sequences or portions of sequences represented by the data. According to one embodiment, a method of identifying patterns in sequences of data points can comprise reading a set of sequential data. The sequential data can comprises a plurality of sequences and each of the plurality of sequences can represent an ordered sequence of tokens. A dotplot representing matches between each sequence of the plurality sequences can be generated. One or more patterns within the sequential data can then be identified based on the dotplot.

A method, system and computer program product for generating answers to questions. In one embodiment, the method comprises receiving an input query, decomposing the input query into a plurality of different subqueries, and conducting a search in one or more data sources to identify at least one candidate answer to each of the subqueries. A ranking function is applied to each of the candidate answers to determine a ranking for each of these candidate answers; and for each of the subqueries, one of the candidate answers to the subquery is selected based on this ranking. A logical synthesis component is applied to synthesize a candidate answer for the input query from the selected the candidate answers to the subqueries. In one embodiment, the procedure applied by the logical synthesis component to synthesize the candidate answer for the input query is determined from the input query.

A computer-implemented method for classifying documents for data loss prevention may include 1) identifying training documents for a machine learning classifier configured for data loss prevention, 2) performing a semantic analysis on training documents to identify topics within the set training documents, 3) applying a similarity metric to the topics to identify at least one unrelated topic with a similarity to the other topics within the plurality of topics, as determined by the similarity metric, that falls below a similarity threshold, 4) identifying, based on the semantic analysis, at least one irrelevant training document within the set of training documents in which a predominance of the unrelated topic is above a predominance threshold, and 5) excluding the irrelevant training document from the set of training documents based on the predominance of the unrelated topic within the irrelevant training document. Various other methods, systems, and computer-readable media are also disclosed.

Methods and arrangements for conducting a search using query logs. A query log is consulted and query rewrite rules are learned automatically based on data in the query log. The learning includes obtaining click-through data present in the query log.

In one embodiment, a plurality of objects associated with a dataset and a specified number of nearest objects to be identified are received. The received objects are sorted in a structured format. Further, a key object and a number of adjacent objects corresponding to the key object are selected from the sorted plurality of objects, wherein the number of adjacent objects is selected based on the specified number of nearest objects to be identified. Furthermore, distances between the key object and the number of adjacent objects are determined to identify the specified number of nearest objects, wherein the distances are determined until the specified number of nearest objects is identified. Based on the determined distances, the specified number of nearest objects in the dataset is identified for data analysis.

Embodiments of the disclosure include a method for partitioning a deterministic finite automaton (DFA) into a plurality of groups. The method includes selecting, with a processing device, a subset of the plurality of states and mapping each state of the subset onto a group of the plurality of groups by assigning one or more transition rules associated with each state to a rule line of the group, wherein each rule line is assigned at most two transition rules and an extended address associated with one of the at most two transition rules. The method also includes iteratively processing each state of the subset mapped onto the group by removing the extended address from each rule line in the group with transition rules referring to a current state if the transition rules in the rule line branch within the group.

A data warehouse is constructed using the relational mapping of a transactional database without reconstructing the data relationships of the transactional database. First, an application programmer analyzes an object model in order to describe facts and dimensions using the objects, attributes, and paths of the object model. Each of the dimensions has an identifier that correlates an item in the transactional database to a dimension record in the data warehouse. The fact and dimension descriptions are saved to a description file. Second, a Data Warehouse Engine (DWE) then access the description file and uses the object model, fact and dimension descriptions, and object-relational mapping to map transactional data to the data warehouse.

Embodiments are described for a system and method of providing a data miner that decouples the analytic flow solution components from the data source. An analytic-flow solution then couples with the target data source through a simple set of data source connector, table and transformation objects, to perform the requisite analytic flow function. As a result, the analytic-flow solution needs to be designed only once and can be re-used across multiple target data sources. The analytic flow can be modified and updated at one place and then deployed for use on various different target data sources.

Methods, systems, and computer-readable media for providing topical search suggestions are provided. Topical search suggestions allow a user to receive search results related to the designated topic or subject matter. The present invention may generate multiple topics based on search input provided by a user. The search input may be a search prefix that includes one or more words entered into the search query box before the completed search query is submitted to the search engine. A search interface then presents the topics derived from the search prefix to a user before the user submits the query. In another embodiment, the user designates multiple search inputs. The present invention generates search results based on the search inputs and then presents topics extracted from the search results. In one embodiment, the topics are extracted by performing a natural language analysis of search result metadata.

A system and method is described for use with a data grid cluster, which uses cluster quorum to prevent split brain scenario. The data grid cluster includes a plurality of cluster nodes, each of which runs a cluster service. Each cluster service collects and maintains statistics regarding communication flow between its cluster node and the other cluster nodes in the data grid cluster. The statistics are used to determine a status associated with other cluster nodes in the data grid cluster whenever a disconnect event happens. The data grid cluster is associated with a quorum policy, which is defined in a cache configuration file, and which specifies a time period that a cluster node will wait before making a decision on whether or not to evict one or more cluster nodes from the data grid cluster.

Provided are processes for the oxidative cleavage of a double bond in an unsaturated carboxylic acid. The process includes contacting the unsaturated carboxylic acid with a mild oxidizing agent and agitating the unsaturated carboxylic acid and the mild oxidizing agent for a time sufficient to cleave a double bond of the unsaturated carboxylic acid and produce a product comprising an aldehyde. The process is typically carried out in a mill, such as a ball, hammer, attrition, or jet mill.

The present invention relates to a cationic lipid having one or more biodegradable groups located in the mid- or distal section of a lipidic moiety (e.g., a hydrophobic chain) of the cationic lipid. These cationic lipids may be incorporated into a lipid particle for delivering an active agent, such as a nucleic acid. The invention also relates to lipid particles comprising a neutral lipid, a lipid capable of reducing aggregation, a cationic lipid of the present invention, and optionally, a sterol. The lipid particle may further include a therapeutic agent such as a nucleic acid.

The present invention relates to pyridazine compounds of formulae I or II and the salts thereof, the N-oxides thereof and the salts of the N-oxides thereof, where the radical A is of the formula A, wherein # denotes the point of attachment to the remainder of formulae I or II, and wherein A1 is N or C—RA1, A2 is N or C—RA2, A3 is N or C—RA3, A4 is N or C—RA4 and A5 is N or C—RA5, provided that one or two of the variables A1, A2, A3, A4 or A5 is N; RA1, RA5, if present, are H, halogen, CN, NO2, C1-C6-alkyl, C1-C6-haloalkyl and the like; RA2, RA4, if present, are H, halogen, CN, NO2, C1-C10-alkyl, C1-C10-haloalkyl and the like; RA3, if present, is H, halogen, CN, NO2, C1-C10-alkyl, C1-C10-haloalkyl and the like; where W is N or C—RW and V is N or C—RV, provided that one of the variables W or V is N; Rt and Rw, if present, are H, halogen, methyl, C1-haloalkyl and the like; Ru and Rv, if present, are H, halogen, C1-C4-alkyl, C1-C3-haloalkyl and the like; X1 is S, O or NR1a, wherein R1a is H, C1-C10-alkyl and the like; X2 is OR2a, NR2bR2c, S(O)mR2d, wherein m is 0, 1 or 2, R2a is C1-C4-alkyl, C1-C4-haloalkyl and the like, R2b, R2c are H, C1-C4-alkyl, C1-C4-haloalkyl and the like, or R2b and R2c together with the nitrogen atom to which they are bound form a heterocycle, and R2d is C1-C4-alkyl, C1-C4-haloalkyl, C3-C6-cycloalkyl and the like; and R1 is H, CN, C1-C10-alkyl and the like. The present invention further relates to a method for controlling invertebrate pests, to a method for protecting plant propagation material and/or the plants which grow therefrom, to plant propagation material, comprising at least one compound according to the present invention, to a method for treating or protecting an animal from infestation or infection by parasites and to an agricultural composition containing at least one compound according to the present invention.

The present application is directed to solid forms of compounds of formula I: and pharmaceutically acceptable salts thereof, that inhibit bacterial gyrase and/or Topo IV and pharmaceutical compositions comprising said compounds and salts. These compounds and salts are useful in treating bacterial infections.

Disclosed is a method for preparing optically pure (+)-ambrisentan and (+)-darusentan, comprising: firstly catalyzing the asymmetric epoxidation of a β-unsaturated alkene using a chiral ketone derived from fructose or a hydrate thereof as a catalyst, and then subjecting the product to an epoxy compound ring-opening reaction and substitution reaction successively to obtain optically pure (+)-ambrisentan and (+)-darusentan.

Herbicidally active 5-amino-1-phenyl-pyrazoles, most of which are new, of the formula ##STR1##

This invention relates to a composition comprising antimony trifluoride and silica, a method for the preparation of said composition and use of said composition as a catalyst in a process for the oxidation of cyclohexanone to ε-caprolactone.

A flame retardant suitable for manufacturing a polymer composition is provided. The polymer composition is used for forming a cured film in which a balance among flame retardancy, adhesion, chemical resistance, heat resistance, and elasticity, and so on, is provided. A flame-retardant polymer composition with an excellent balance among the above properties is also provided. The flame retardant of the invention has a structure of Formula (1), (2), or (3): (in which, R1 is hydrogen or methyl, R2 is C2-20 alkylene or C2-20 alkylene in which any —CH2— is replaced by —O—, R3 and R4 are C1-20 alkyl, phenyl, and phenyl substituted by C1-5 alkyl or phenyl, R3 and R4 may also be an integrally-formed cyclic group, and p and q are 0 or 1).

According to one embodiment, a glass container may include a body formed from a Type I, Class B glass composition according to ASTM Standard E438-92. The body may have an inner surface, an outer surface and a wall thickness extending between the outer surface and the inner surface. The body may also include a compressively stressed layer extending into the wall thickness from at least one of the outer surface and the inner surface. A lubricous coating may be positioned on at least a portion of the outer surface of the body, wherein the outer surface of the body with the lubricous coating has a coefficient of friction less than or equal to 0.7.

In certain embodiments novel nanoparticles (nanowontons) are provided that are suitable for multimodal imaging and/or therapy. In one embodiment, the nanoparticles include a first biocompatible (e.g., gold) layer, an inner core layer (e.g., a non-biocompatible material), and a biocompatible (e.g., gold) layer. The first gold layer includes a concave surface that forms a first outer surface of the layered nanoparticle. The second gold layer includes a convex surface that forms a second outer surface of the layered nanoparticle. The first and second gold layers encapsulate the inner core material layer. Methods of fabricating such nanoparticles are also provided.

Methods and apparatus for output of high-bandwidth debug data/traces in electronic devices using embedded high-speed debug port(s). Debug data is received from multiple blocks and buffered in a buffer. The buffer's output is operatively coupled to one or more high-speed serial I/O interfaces via muxing logic during debug test operations. The buffered data is encoded as serialized data and sent over the one or more high-speed serial I/O interfaces to a logic device that receives serialized data and de-serializes it to generate parallel debug data that is provided to a debugger. The buffer may be configured as a bandwidth-adapting buffer that facilitates transfer of debug data that is received at a variable combined data rate outbound via the one or more high-speed serial I/O interfaces at a data rate corresponding to the bandwidth of the serial I/O interfaces.

Embodiments relate to a computer implemented information processing system, method and program product for data access. The information processing system includes a data store having a top tier store and at least another tier store with the top tier store including a counter for each entry of a symbol and another tier store including a representative frequency value defined for the another tier store. A sorter is also provided configured to sort the symbol in the top tier store and the another tier stores according to a value generated in the counter for the assessed symbol. The said sorter is also configured to restore entry of the symbol in the top tier store, in response to a symbol having moved from said top tier store to another tier store, by using the representative frequency value defined for said another store to which said symbol was moved.

A double data rate memory physical interface having self checking loopback logic on-chip is disclosed. Disposed on the chip is a first linear feedback shift register, which is capable of generating a set of test data values that comprise at least two data bits. Also disposed on the chip is a second linear feedback shift register. The second linear feedback shift register is capable of generating a set of expected data values that match the test data values. Further, an internal loopback error check element is disposed on the chip. The internal loopback error check element is used to compare the set of expected data values with the set of test data values.

Method and apparatus for managing data in a memory. In accordance with some embodiments, a first data object and an associated first ECC data set are generated and stored in a non-volatile (NV) main memory responsive to a first set of data blocks having a selected logical address. A second data object and an associated second ECC data set are generated responsive to receipt of a second set of data blocks having the selected logical address. The second data object and the second ECC data set are subsequently stored in the in the NV main memory responsive to a mismatch between the first ECC data set and the second ECC data set.

Within a radio communication network infrastructure transmitting data organized into a sequence of symbols to a receiving device over a plurality of radio links, data to be transmitted is encoded according to an error correction coding scheme in order to produce a set of systematic symbols and a set of corresponding redundancy symbols; the systematic symbols and a first subset of the corresponding redundancy symbols are transmitted, over a first radio link among said plurality of radio links, in broadcast mode, and a second subset of the corresponding redundancy symbols, distinct from the first one, is transmitted over a second radio link among said plurality of radio links.

A method of transmitting data according to a data transmission protocol wherein the data is transmitted as a plurality of data frames and each data frame includes an error checking field comprising at least two sub-fields, the data of the first sub-field being formed by a first error checking method performed on data of the frame and the data of the second sub-field being formed by a second error checking method performed on the said data of the frame, the first and second methods being such that the data of the first sub-field has different error checking properties from those of the data of the second sub-field.

A method includes determining a read threshold voltage corresponding to a group of storage elements in a non-volatile memory that includes a three-dimensional (3D) memory of a data storage device. The method also includes determining an error metric corresponding to data read from the group of storage elements using the read threshold voltage. The method includes comparing the read threshold voltage and the error metric to one or more criteria corresponding to a corrupting event.

Methods and systems for in-place updating original content stored in a non-volatile storage device and for yielding updated content. Some of the described embodiments illustrate the possibilities for reduction in storage operations, storage blocks, and/or update package size. Some of the described embodiments include the writing of error recovery result(s) such as XOR result(s) which enable the recovery of data in case of an interruption of the update process. In some of the described embodiments, there is re-usage of a protection buffer containing content which is required in the update process.