z Efficacy of Melatonin in Children With Postconcussive Symptoms: A Randomized Clinical Trial By pediatrics.aappublications.org Published On :: 2020-04-01T01:00:57-07:00 BACKGROUND: Approximately 25% of children with concussion have persistent postconcussive symptoms (PPCS) with resultant significant impacts on quality of life. Melatonin has significant neuroprotective properties, and promising preclinical data suggest its potential to improve outcomes after traumatic brain injury. We hypothesized that treatment with melatonin would result in a greater decrease in PPCS symptoms when compared with a placebo. METHODS: We conducted a randomized, double-blind trial of 3 or 10 mg of melatonin compared with a placebo (NCT01874847). We included youth (ages 8–18 years) with PPCS at 4 to 6 weeks after mild traumatic brain injury. Those with significant medical or psychiatric histories or a previous concussion within the last 3 months were excluded. The primary outcome was change in the total youth self-reported Post-Concussion Symptom Inventory score measured after 28 days of treatment. Secondary outcomes included change in health-related quality of life, cognition, and sleep. RESULTS: Ninety-nine children (mean age: 13.8 years; SD = 2.6 years; 58% girls) were randomly assigned. Symptoms improved over time with a median Post-Concussion Symptom Inventory change score of –21 (95% confidence interval [CI]: –16 to –27). There was no significant effect of melatonin when compared with a placebo in the intention-to-treat analysis (3 mg melatonin, –2 [95% CI: –13 to 6]; 10 mg melatonin, 4 [95% CI: –7 to 14]). No significant group differences in secondary outcomes were observed. Side effects were mild and similar to the placebo. CONCLUSIONS: Children with PPCS had significant impairment in their quality of life. Seventy-eight percent demonstrated significant recovery between 1 and 3 months postinjury. This clinical trial does not support the use of melatonin for the treatment of pediatric PPCS. Full Article
z Continuous Albuterol With Benzalkonium in Children Hospitalized With Severe Asthma By pediatrics.aappublications.org Published On :: 2020-04-01T01:00:57-07:00 BACKGROUND AND OBJECTIVES: The albuterol dropper bottle used to prepare solutions for continuous nebulization contains the preservative benzalkonium chloride (BAC). BAC, by itself, has been shown to cause bronchospasm. We hypothesized that BAC would decrease the therapeutic efficacy of albuterol in patients with acute asthma exacerbations. METHODS: We performed a retrospective cohort study comparing the clinical outcomes of patients <18 years of age receiving continuous nebulized albuterol with and without BAC. For the primary end point (duration of continuous albuterol nebulization), we compared the 2 groups with Kaplan-Meier estimate of survival curves, conducted a log-rank test of difference, and adjusted for baseline characteristics using multivariable Cox regression. A P value <.05 was considered significant. RESULTS: A total of 477 patients were included in the analysis (236 exposed to BAC and 241 controls). The duration of continuous nebulization was significantly longer in the BAC group than in the control group (median of 9 vs 6 hours; 15.7% required continuous nebulization compared to 5.8% of controls at 24 hours). The control group was 79% more likely to stop continuous nebulization at any particular point in time (hazard ratio 1.79; 95% confidence interval: 1.45 to 2.22; P < .001) and 43% more likely to stop additional respiratory support (hazard ratio 1.43; 95% confidence interval: 1.16 to 1.75; P < .001). CONCLUSIONS: BAC is a functional albuterol antagonist associated with a longer duration of continuous albuterol nebulization treatment and additional respiratory support, suggesting that preservative-free albuterol formulations are safer for use in continuous nebulization. Full Article
z Zoho Books By www.pcmag.com Published On :: Zoho Books is an excellent choice for cloud-based small business accounting, with an exceptional interface, an attractive price, and a rich set of tools. Its limited payroll offering may cause some users to look elsewhere, however. Full Article
z Leipzig v Tottenham facts By www.uefa.com Published On :: Fri, 21 Feb 2020 10:00:00 GMT Timo Werner's penalty has given Leipzig a narrow advantage, although Spurs have history when it comes to turning round a 1-0 home defeat. Full Article comp_matches
z Seizing every opportunity By feedproxy.google.com Published On :: Fri, 02 Aug 2019 14:18:42 +0000 Buenos Aires, Argentina :: Maintenance crew share Christ's love with local welders helping repair Logos Hope. Full Article
z Hintzes commit $100,000 for emergency aid to students By news.psu.edu Published On :: Thu, 30 Apr 2020 07:58 -0400 Two of Penn State’s most generous supporters and prominent alumni leaders have made a new commitment to support students impacted by the COVID-19 crisis. Helen S. Hintz, 1960, and Edward “Ed” R. Hintz, 1959, have directed $100,000 to the Student Care and Advocacy Emergency Fund. Full Article
z Fin24.com | Gauteng, Western Cape and KZN top list for card fraud By www.fin24.com Published On :: Thu, 14 Dec 2017 13:53:42 +0200 Gauteng, the Western Cape and KwaZulu-Natal are the hot spots for card fraud in South Africa, according to a report on global fraud activity. Full Article
z COVID-19 in Children: Initial Characterization of the Pediatric Disease By pediatrics.aappublications.org Published On :: 2020-04-08 Andrea T. CruzApr 8, 2020; 0:peds.2020-0834v2-e20200834COMMENTARY Full Article
z Germany's Martinez equals UEFA finals scoring record By www.uefa.com Published On :: Mon, 21 May 2018 19:29:00 GMT Germany's Shekiera Martinez, at 16, has written herself into UEFA's record books by scoring nine goals in a final tournament. Full Article general
z Fin24.com | Coronavirus and investment: Keep your eye on the long-term prize By www.fin24.com Published On :: Sat, 04 Apr 2020 19:54:16 +0200 The "scare" reaction in the markets due to the coronavirus pandemic, has removed "froth" and returned risk markets to much fairer valuations, says an investment expert. Full Article
z The Bizarre Disdain for High School Sports By feedproxy.google.com Published On :: Mon, 18 Mar 2019 00:00:00 +0000 Students who play high school sports get better grades, select more challenging courses, and are more likely to enroll in college. Full Article Sports
z Slade recognized with Jackson Lethbridge Tolerance Award By news.psu.edu Published On :: Thu, 09 Apr 2020 06:52 -0400 Ebonie Slade, a senior majoring in biobehavioral health at Penn State Greater Allegheny, is the recipient of the 2020 Jackson Lethbridge Tolerance Award. Full Article
z Cybersecurity professional speaks to students via Zoom By news.psu.edu Published On :: Fri, 10 Apr 2020 14:17 -0400 Penn State Greater Allegheny’s current students recently joined a virtual conversation about Cybersecurity Analytics and Operations, Greater Allegheny’s newest 4-year program starting this fall. Full Article
z Seizing every opportunity By feedproxy.google.com Published On :: Fri, 02 Aug 2019 14:18:42 +0000 Buenos Aires, Argentina :: Maintenance crew share Christ's love with local welders helping repair Logos Hope. Full Article
z New Penn State Hazleton scholarship supports students in STEM By news.psu.edu Published On :: Thu, 05 Mar 2020 09:24 -0500 A new endowed scholarship has been created to support those studying science, technology, engineering or math at Penn State Hazleton. Full Article
z Penn State Hazleton fall 2019 dean's list announced By news.psu.edu Published On :: Mon, 30 Mar 2020 11:46 -0400 More than 200 students from Penn State Hazleton were recently named to the dean’s list for the fall 2019 semester. Full Article
z Hazleton native joins campus athletics department as new trainer By news.psu.edu Published On :: Thu, 09 Apr 2020 16:38 -0400 Hazleton native Megan Bobish has joined the Penn State Hazleton Athletics Department as the newest member of its team. Full Article
z Virtual services keeping Hazleton students, campus connected during crisis By news.psu.edu Published On :: Fri, 10 Apr 2020 11:54 -0400 Penn State Hazleton’s Student Services and Engagement team is continuing to forge personal connections with students while operating under the restrictions in the virtual environment created by the COVID-19 crisis. Full Article
z Couple pledges $100K estate gift to Penn State Hazleton By news.psu.edu Published On :: Sat, 11 Apr 2020 11:28 -0400 Drs. William and Jean Lovrinic have made an estate commitment to Penn State that will establish a $100,000 scholarship fund at Penn State Hazleton. Full Article
z Fish, wine, and social media: Hazleton virtual research fair winners announced By news.psu.edu Published On :: Thu, 30 Apr 2020 10:19 -0400 Wine, fish, and excessive use of social media were a few of the topics that earned students top honors in Penn State Hazleton's first-ever virtual Undergraduate Research Fair. Full Article
z Zaragoza to stage UEFA Futsal Cup finals By www.uefa.com Published On :: Thu, 07 Dec 2017 15:01:00 GMT The 10,700-capacity Pabellón Príncipe Felipe in Zaragoza will host the UEFA Futsal Cup finals in April involving Spain's Inter FS and Barcelona plus Portugal's Sporting CP and Győr of Hungary. Full Article general
z Amazon Music Unlimited vs. Spotify: How Do They Compare? By www.pcmag.com Published On :: The big difference between Spotify and Amazon Music Unlimited is Amazon offers an affordable tier of service available on just one Echo device. Here's how else they differ. Full Article
z Velocity Micro Raptor Z55a (Ryzen 9 3950X) By www.pcmag.com Published On :: The Velocity Micro Raptor Z55a is a clean, straightforward gaming desktop with excellent performance. It's a bit pricey, though, and doesn't do a lot to differentiate itself from its rivals. Full Article
z Deals: Acer Computers, Blink XT2, 65-Inch Vizio P-Series Quantum X By www.pcmag.com Published On :: Amazon is offering up to 30 percent off Acer laptops, desktops, and monitors. Plus, you can save $930 on the 65-inch Vizio P-Series Quantum X 4K TV. Full Article
z The Best Android Launchers for Home Screen Customization By www.pcmag.com Published On :: Don't settle for the default settings on your Android device. With the right launcher, you can customize the screens and layouts of your phone. Full Article
z The 30 Best Amazon Fire Tablet Apps By www.pcmag.com Published On :: Amazon Fire is more than just an e-reader. Download some of the best apps from Amazon's Appstore to have fun, be productive, and get more organized. Full Article
z Weekend Deals: Logitech Webcam, 65-Inch Vizio, Dell Inspiron 15 5000 By www.pcmag.com Published On :: The Logitech C920 1080p webcam is back down to its Prime Day price, the 65-inch Vizio P-Series Quantum 4K TV is on sale for less than $1,000, and you can grab the new Dell Inspiron 15 5000 plus a $100 Visa prepaid card for just $600. Full Article
z Deals: Amazon Echo Dot, 55-Inch Vizio 4K Smart TV, More By www.pcmag.com Published On :: Right now you can grab an Amazon Echo Dot two-speaker bundle for just $50. Plus, the 55-inch Vizio M-Series Quantum 4K Smart TV and Anker charging accessories are on sale. Full Article
z PNY Flash Drives, Memory Cards Are Up to 64 Percent Off at Amazon By www.pcmag.com Published On :: You don't have to fork over a bunch of cash to get a bunch of storage. PNY flash drives, SD cards, and portable drives are on sale at Amazon, with prices starting as low as $5.84. Full Article
z Deals: Vizio M-Series 4K TV, XPS 15 With 4K OLED, Roborock S5 By www.pcmag.com Published On :: The 55-inch Vizio M-Series 4K TV is just $358, $40 less than its Black Friday price. Plus, Dell's XPS 15 laptop is $350 off and the Roborock S5 robot vacuum is $200 off. Full Article
z Pre-Super Bowl Deals: Vizio TVs, Samsung Soundbar, Roku Premiere By www.pcmag.com Published On :: Save on a new TV, soundbar, or media streamer for the Big Game. Plus, the best deals of the week, including discounts on AirPods, Roombas, and Dell's XPS 13 laptop, are all still available. Full Article
z Ian Blackford hits out at family's 800-mile holiday to Motherwell as Scots poke fun at bizarre trip By www.heraldscotland.com Published On :: Sat, 09 May 2020 12:07:16 +0100 A family who was fined for travelling more than 400 miles for the bank holiday weekend have been slammed online by politicians and Scots. Full Article
z Scholastic awards recognize academic excellence at Penn State Berks By news.psu.edu Published On :: Wed, 29 Apr 2020 09:15 -0400 Forty-nine Penn State Berks students received recognition for the University Scholastic awards on April 2, through personalized emails. The awards presented included the Evan Pugh Scholars Award, Full Article
z New Law Expanding Vouchers Placed on Hold in Arizona By feedproxy.google.com Published On :: Tue, 22 Aug 2017 00:00:00 +0000 Arizona's ambitious expansion of its school voucher program has officially been put on hold after opponents filed enough signatures to at least temporarily block the new law. Full Article Vouchers
z Expansion of School Vouchers Gets Trounced in Arizona By feedproxy.google.com Published On :: Wed, 07 Nov 2018 00:00:00 +0000 Proposition 305 had become one of the most contentious ballot-box battles over school choice in the 2018 midterm elections. But its loss is not necessarily a defeat for school choice advocates. Full Article Vouchers
z Vouchers Expansion Battle Will Be Fought at Arizona Polls By feedproxy.google.com Published On :: Tue, 30 Oct 2018 00:00:00 +0000 A ballot measure to expand the state's eligibility for so-called education savings account is contentious and confusing. Full Article Vouchers
z Elizabeth Warren's Position on Vouchers: A Review By feedproxy.google.com Published On :: Wed, 23 Oct 2019 00:00:00 +0000 Massachusetts Sen. Elizabeth Warren's education plan landed on Monday, and among other consequences, it led to a conversation about her past statements addressing "vouchers." Full Article Vouchers
z Randomized Placebo-controlled Trial of a 42-Day Tapering Course of Dexamethasone to Reduce the Duration of Ventilator Dependency in Very Low Birth Weight Infants: Outcome of Study Participants at 1-Year Adjusted Age By pediatrics.aappublications.org Published On :: 1999-07-01 T. Michael O'SheaJul 1, 1999; 104:15-21ARTICLES Full Article
z Longitudinal Growth of Hospitalized Very Low Birth Weight Infants By pediatrics.aappublications.org Published On :: 1999-08-01 Richard A. EhrenkranzAug 1, 1999; 104:280-289ARTICLES Full Article
z Trends in Bronchiolitis Hospitalizations in the United States, 2000-2009 By pediatrics.aappublications.org Published On :: 2013-07-01 Kohei HasegawaJul 1, 2013; 132:28-36ARTICLES Full Article
z Supplemental Therapeutic Oxygen for Prethreshold Retinopathy of Prematurity (STOP-ROP), A Randomized, Controlled Trial. I: Primary Outcomes By pediatrics.aappublications.org Published On :: 2000-02-01 The STOP-ROP Multicenter Study GroupFeb 1, 2000; 105:295-310ARTICLES Full Article
z Prolonged Duration of Initial Empirical Antibiotic Treatment Is Associated With Increased Rates of Necrotizing Enterocolitis and Death for Extremely Low Birth Weight Infants By pediatrics.aappublications.org Published On :: 2009-01-01 C. Michael CottenJan 1, 2009; 123:58-66ARTICLES Full Article
z Unexpected Increased Mortality After Implementation of a Commercially Sold Computerized Physician Order Entry System By pediatrics.aappublications.org Published On :: 2005-12-01 Yong Y. HanDec 1, 2005; 116:1506-1512ARTICLES Full Article
z Palivizumab, a Humanized Respiratory Syncytial Virus Monoclonal Antibody, Reduces Hospitalization From Respiratory Syncytial Virus Infection in High-risk Infants By pediatrics.aappublications.org Published On :: 1998-09-01 The IMpact-RSV Study GroupSep 1, 1998; 102:531-537ARTICLES Full Article
z England presented with Maurice Burlaz Trophy By www.uefa.com Published On :: Wed, 06 Dec 2017 08:01:00 GMT England won the 2017 Maurice Burlaz Trophy, the prize awarded to the nation that achieved the best results in UEFA's men's youth competitions over the previous two seasons. Full Article general
z Martínez Munuera ready for final step on U19 journey By www.uefa.com Published On :: Sat, 28 Jul 2018 18:38:00 GMT "I'm sure that when I get home, I'll be a better referee than when I arrived here." - We meet U19 EURO final referee Juan Martínez Munuera. Full Article general
z Portugal pair share U19 EURO top scorers' prize By www.uefa.com Published On :: Sun, 29 Jul 2018 22:18:00 GMT U19 EURO winners Trincão Francisco and João Filipe were also winners in the race for the golden boot at the tournament, finishing tied at the top with five goals. Full Article general
z Penn State Harrisburg recognizes staff with 25 years of service By news.psu.edu Published On :: Wed, 22 Apr 2020 12:00 -0400 Penn State Harrisburg this spring recognized staff members who have served the college for 25 years. Full Article
z Penn State Harrisburg recognizes spring 2020 student marshals By news.psu.edu Published On :: Mon, 27 Apr 2020 12:50 -0400 Penn State Harrisburg has selected six graduates to represent each academic school and graduate studies as student marshals for spring 2020. Full Article
z Penn State Harrisburg recognizes student achievement By news.psu.edu Published On :: Wed, 29 Apr 2020 13:51 -0400 Penn State Harrisburg recently honored students for accomplishments in academics, service, and leadership. Full Article