y [ASAP] Scaffold Repurposing of in-House Chemical Library toward the Identification of New Casein Kinase 1 d Inhibitors By feedproxy.google.com Published On :: Mon, 04 May 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00028 Full Article
y [ASAP] Development of a Raltegravir-based Photoaffinity-Labeled Probe for Human Immunodeficiency Virus-1 Integrase Capture By feedproxy.google.com Published On :: Tue, 05 May 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00009 Full Article
y [ASAP] Substituted Azabicyclo[2.2.1]heptanes as Selective Orexin-1 Antagonists: Discovery of JNJ-54717793 By feedproxy.google.com Published On :: Tue, 05 May 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00085 Full Article
y [ASAP] De-risking Drug Discovery of Intracellular Targeting Peptides: Screening Strategies to Eliminate False-Positive Hits By feedproxy.google.com Published On :: Tue, 05 May 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00022 Full Article
y [ASAP] Synthesis and Evaluation of <sup>11</sup>C- and <sup>18</sup>F-Labeled SOAT1 Inhibitors as Macrophage Foam Cell Imaging Agents By feedproxy.google.com Published On :: Wed, 06 May 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00127 Full Article
y [ASAP] Ligand Design for Cereblon Based Immunomodulatory Therapy By feedproxy.google.com Published On :: Fri, 08 May 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00214 Full Article
y Germany Facing Mass Blackouts Because The Wind And Solar Won’t Cooperate By latestsolarnews.com Published On :: Sat, 04 Mar 2017 19:59:09 +0000 Germany’s energy network nearly broken down in January because of poor execution from wind turbines and sun based boards, as indicated by information from a noteworthy exchange union. Wind and sunlight based power plants failed to meet expectations in January, 2017, as a result of shady climate with almost no wind, setting the phase for … The post Germany Facing Mass Blackouts Because The Wind And Solar Won’t Cooperate appeared first on LatestSolarNews. Full Article News
y Tanzania turns to solar power to increase electricity connectivity By latestsolarnews.com Published On :: Mon, 17 Apr 2017 22:05:48 +0000 As many as 60 percent of the Kenyan population now has access to electricity according to official data. But in neighbouring Tanzania, the penetration rate is less than half of that and sparsely populated rural communities are especially neglected. The post Tanzania turns to solar power to increase electricity connectivity appeared first on LatestSolarNews. Full Article News
y Solar Powered Lights For The Yard By latestsolarnews.com Published On :: Wed, 26 Jul 2017 21:41:45 +0000 Reading about the various sofas reviews here and choosing amongst them to match your patio is not that difficult when compared to doing the entire electrical work of the patio. When you are lighting your patio the exact opposite thing you need to do is to be stumbling over electrical lines and attempting to put … The post Solar Powered Lights For The Yard appeared first on LatestSolarNews. Full Article installations Why Solar
y New Solar Plant In Chile To Power 13,000 Homes Per Year By latestsolarnews.com Published On :: Thu, 14 Dec 2017 01:36:55 +0000 Chile is building a brand new solar power plant that has some exciting outcome on the future. The plant is expected to provide energy on day and night as well as throughout inclement weather, to power up to 13,000 homes annually. This project will make Chile one of the top solar energy spots in the … The post New Solar Plant In Chile To Power 13,000 Homes Per Year appeared first on LatestSolarNews. Full Article solar news
y India is planning to achieve 50 GW of prodction from renewbale energy by 2028 By latestsolarnews.com Published On :: Tue, 08 Jan 2019 10:08:19 +0000 India is planning to achieve 50 gigawatt (GW) of production from renewable energy by 2028, in order to get to its goal of 40 per cent of electricity generation from non-fossil fuels by 2030, Ministry of New and Renewable Energy secretary, Anand Kumar said at the India-Norway Business Summit 2019 in New Delhi. Of this … The post India is planning to achieve 50 GW of prodction from renewbale energy by 2028 appeared first on LatestSolarNews. Full Article News india solar energy india
y A BEM syntax with UX in mind By simurai.com Published On :: Thu, 24 Oct 2013 00:00:00 +0000 At some point, while working on the MontageJS framework, the question came up what CSS naming convention we should start using. After a long discussion we settled on using the BEM methodology, but changed the syntax a bit. To keep this post short, I won’t go into detail why using BEM is a good idea, but rather explain why we chose a different syntax. Here some examples: .digit-Progress /* org-Component */ .digit-Progress-bar /* org-Component-childElement */ .digit-Progress--small /* org-Component--variation */ Note: The org- (digit-) prefix is used as a name-space so it wouldn’t conflict with other packages/libraries/frameworks. Now let’s take a look at the reasons for choosing such a syntax. Hyphens (-) The main reason why we’re using a hyphen (-) instead of underscores (_), has to do with the fact that their behavior is different when double-clicking to select text. Try for yourself: component__element /* underscores */ component-element /* hyphen */ See how when you’re using underscores it selects the part before and after, in this case the whole component__element. But with hyphens it let’s you select only the part you double-clicked. component OR element. This let’s you quickly edit only the parts you want: camelCase Now, what if the component or child element consists of multiple words? We could use underscores like component_name-element_name. It would still be double-clickable, but readability suffers since it’s harder to see what belongs together. Better to use camelCase which groups each part visually: componentName-elementName. MainComponent OK, I think we’re getting closer. As a last rule, for the “main” component we use PascalCase. The reason for it is to add emphasis and make it easier to distinguish the main component from a child element. Also when using a namespace, the component moves to the second position, which makes it even more important to have it stick out: org-Component-childElement –variation We kept the more commonly used double hyphens (–) for variations. digit-Progress--small. It makes sense, because it pulls the variation (–small) visually more apart and makes it look like it’s something “different” than the default component. So that’s about it. For more details about this naming convention, take a look at the SUIT framework, which also started to use the same syntax and documented it really well. In the end, whatever Shade of BEM you choose to cook with probably depends on your personal taste, but thinking about a great UX by improving usability and readability won’t hurt either. Full Article
y Moving to Jekyll By simurai.com Published On :: Sun, 02 Feb 2014 00:00:00 +0000 I haven’t redesigned my site for years, can’t even remember exactly. Also, haven’t been posting for a while. So as a New Year’s resolution I redid my site using Jekyll and am hosting it as a GitHub page. Full Article
y Styling with STRINGS By simurai.com Published On :: Sun, 04 May 2014 00:00:00 +0000 At this year’s CSSConf in Melbourne (AU) I gave a talk called “Styling with STRINGS”. The talk is about how we can use Flexbox, currentColor and __EM__s inside components to quickly style entire Web Apps straight in the browser. In case of tl:dw here some of the main points: Layout When creating mobile “App” layouts, where not the whole page is scrollable, but instead only certain parts. And you have anchored areas like header/footer and a main area that should fill out the available space, then the easiest way is to use Flexbox. This lets you easily drag around components that are set as flex items and they always position nicely. Using flex: 1; on components makes them stretch out and fill the available space. A good use case is a search input or a title. Color If you don’t specify the border-color (initial value) it will be the same value as color. Furthermore there is a color value called currentColor. As the name indicates, it’s also mapped to the current color value. We can use it as background-color for example. Not that useful when the text should be readable, since now text and background are the same color, but for some components without text it can be quite useful. Like in the example below with the slider thumb. If a component set should look similar to the “iOS 7” style then currentColor works great. Below all components have no color values at all and only use currentColor. This let’s us change everything by only changing the color value in the root html element. Size In a similar way, EMs are mapped to font-size. So if we use EMs to define only the proportions of a component, we can use font-size to scale it up/down. And if we inherit the font-size we could also control everything at once with just a single property in the root or in groups if we go deeper down the DOM tree. REMs work the same except that they are tied to the root html element only. We could use it to control the spacing of the components by using REMs for margin/padding. I wrote about this in more detail in the Sizing (Web) Components post. All together Now if we combine this all and test it in an example application, we can easily design many variations right from the DevTools/inspector in a quick and easy way. Feel free to play around with the CSSConf App yourself or check out the source on GitHub. How to save? You might wonder how you can save the changes made in the DevTools/inspector without having to manually copy them over into your CSS file. In Chrome there is a feature called Workspaces. It let’s you map a URL to a local folder. Once that is setup, all CSS changes will automatically be saved to your local disc. Here a post that explains how to setup Workspaces. It’s advised to use version control like Git, so that you can always discard all changes if you went too far and wanna start over. Conclusion Admittedly it is somewhat in between of being useful for production and just a “hack”. Especially the currentColor. But the main point of the talk is best told by this quote: “Creators need an immediate connection” — Bret Victor The examples I used are just the closest I could get using CSS alone and still keep code clean. I hope we keep that principle alive and improve on it. ps. Artist of the puppet master illustration: Unknown. pss. Here all the other videos from CSSConf. Full Article
y Contextual styling with custom properties By simurai.com Published On :: Sun, 01 Apr 2018 00:00:00 +0000 Something I’ve been wanting for a long time, define different regions like a footer section, or side bar and not have to deal with all the contextual styling hassle. A.k.a. “Now that this button is used on a dark background, the button needs to change its colors too. Where should the styles live?”. Here an old post about struggling with contextual styling. So then the other day I was doing some experiments with using custom properties for Atom’s UI. Turns out, using custom properties might make contextual styling a bit easier. For the rest of the post, let’s switch to a more simple example. A page where the main area is light, but then has a dark hero and footer section. Like this: In the past, I probably would’ve created variations like Button--dark or overwrote it with header .Button {…}. Depends a bit on the project. Here another approach: Create themes with a set of variables, then apply the theme to the different areas. 1. Default theme First let’s define our default theme with a bunch of variables. [data-theme="default"] { --fg: hsl(0,0%,25%); --border: hsl(0,0%,75%); --bg: hsl(0,0%,95%); --button-bg: hsl(0,0%,99%); --input-bg: hsl(0,0%,90%); } Then we create some components where we use the variables defined above. [data-theme] { color: var(--fg); background-color: var(--bg); } .Button { color: var(--fg); border: 1px solid var(--border); background-color: var(--button-bg); } .Input { color: var(--fg); border: 1px solid var(--border); background-color: var(--input-bg); } And lastly we add the [data-theme="default"] attribute on the body so that our components will pick up the variables. <body data-theme="default"> If you wonder why use data-theme attributes over classes? Well, no specific reason. Maybe with attributes, it’s a hint that only one theme should be used per element and is more separated from your other classes. At this point we get this: See the Pen Contextual styling with custom properties (1/3) by simurai (@simurai) on CodePen. 2. Dark theme But our designer wants the hero and footer to be dark. Alright, let’s define another theme region. [data-theme="dark"] { --fg: hsl(0,10%,70%); --border: hsl(0,10%,10%); --bg: hsl(0,0%,20%); --button-bg: hsl(0,0%,25%); --input-bg: hsl(0,0%,15%); } And add the theme attribute to the header and footer. <header data-theme="dark"> <footer data-theme="dark"> Which gives us this: See the Pen Contextual styling with custom properties (2/3) by simurai (@simurai) on CodePen. The reason why this works is that custom properties cascade and can be overridden on nested elements, just like normal properties. 3. Hero theme A few months pass and our designer comes back with a redesigned hero section. “To make it look fresh” with a splash of color. No problem! Just like with the dark theme, we define a new “hero” theme. [data-theme="hero"] { --fg: hsl(240,50%,90%); --border: hsl(240,50%,10%); --bg: hsl(240,33%,30%); --button-bg: hsl(240,33%,40%); --input-bg: hsl(240,33%,20%); } <header data-theme="hero"> And here is that fresh hero: See the Pen Contextual styling with custom properties (3/3) by simurai (@simurai) on CodePen. It’s also not limited to colors only, could be used for sizes, fonts or anything that makes sense to define as variables. Benefits Using these theme “regions” lets your components stay context un-aware and you can use them in multiple themes. Even on the same page. Developers can add components, move components around, without having to know about in what context (theme) they live. The markup for the components stays the same. Design systems authors can create new components without worrying about where they get used, the variables used in components stay the same. Designers can define new theme regions, or change existing ones, without having to make changes to a component’s HTML or CSS, it stays the same. Less time to talk about who, how and where, more time to talk about the weather. ☔️???? Concerns Yeah, right. The big question: But does it scale? Can this be used for all use cases. Ok, I’m pretty sure it doesn’t fit all situations. There are just too many to find a single solution for them all. And I’m actually not sure how well it scales. I guess it works great in these simple demos, but I have yet to find a larger project to test it on. So if you have used (or plan to use) this approach, I’m curious to know how it went. A concern I can imagine is that the list of variables might grow quickly if themes have totally different characteristics. Like not just a bit darker or lighter backgrounds. Then you might need to have foreground and border colors for each component (or group of components) and can’t just use the general --fg and --border variables. Naming these variables is probably the hardest part. Update I @giuseppegurgone made an interesting comment: in suitcss projects I used to define component level custom props, theme variables and then create themes by mapping the former to the latter suitcss-toolkit So if I understood it correctly, by mapping theme variables to component variables, you could avoid your theme variables from growing too much and you can decide for each component how to use these theme variables. Update II If it’s too early to use custom properties in your project, @szalonna posted an example how to do something similar in SCSS. Full Article
y Unlock Your Team’s Potential With Teamstack By www.webdesignerdepot.com Published On :: Tue, 21 Apr 2020 10:45:38 +0000 Teamstack is a password manager for your whole team. Running in the cloud it allows you to manage your tools and resources, and seamlessly scale your teams’ access, from a single, easy-to-use control panel. Teamstack is powerful, and secure with multi-factor authentication, single sign-in, SAML and form-based authentication. It works with desktop and mobile apps, […] Full Article Sponsored multi-factor authentication password management secure apps secure logins team passwords Teamstack
y Email Personalization: Your Secret To Better Engagement By www.webdesignerdepot.com Published On :: Wed, 29 Apr 2020 10:45:54 +0000 One of the struggles that marketers face is how to send the right message at exactly the right time to target people in a way that will appeal to them. To solve the problem, businesses need to get themselves acquainted with new technologies and the power of personalization. In the past few years, digital marketing […] Full Article Search & Marketing customer funnel email engagement email marketing marketing tips personalized email
y Popular Design News of the Week: April 27, 2020 – May 3, 2020 By www.webdesignerdepot.com Published On :: Sun, 03 May 2020 10:45:45 +0000 Every week users submit a lot of interesting stuff on our sister site Webdesigner News, highlighting great content from around the web that can be of interest to web designers. The best way to keep track of all the great stories and news being posted is simply to check out the Webdesigner News site, however, […] Full Article News Apps Best Of Compilation CSS Design Fonts Freelancing Google Graphic Design illustration Inspiration responsive design Social Media Typography Usability ux design Web Design Web Development
y 3 Essential Design Trends, May 2020 By www.webdesignerdepot.com Published On :: Mon, 04 May 2020 10:45:56 +0000 The state of the world around us can greatly impact website design. From emotional changes that correlate to the feel of a design to information and data to deliver, the impact of the worldwide COVID-19 pandemic is making its way into projects (intentionally or not). Here’s what’s trending in design this month. 1. “Unbalanced” Use […] Full Article Community & Inspiration design inspiration design trends new design ideas trending web design web design trends
y 8 of the Top WP Multipurpose Themes That You Can Use By www.webdesignerdepot.com Published On :: Tue, 05 May 2020 10:45:00 +0000 More than a few multipurpose WordPress themes have become big sellers in recent years, and for a reason. Actually, for several reasons. One reason is they serve as excellent toolkits for web designers who have large and varied clienteles. The best multipurpose themes, like those presented here, are popular for other reasons as well. They […] Full Article Sponsored Best WordPRess themes BeTheme Top WP themes Total WordPress Theme Wordpress Themes
y Thanks to Covid-19, Website Accessibility Has Never Been More Important By www.webdesignerdepot.com Published On :: Thu, 07 May 2020 10:45:59 +0000 The first global pandemic of the digital era is upon us. We’re living in unprecedented and uncomfortable times. For our senior citizens, these past several weeks have been particularly discomforting. According to the CDC, men and women over the age of 65 are significantly more likely to develop complications from COVID-19. As we seek to […] Full Article Interactive Design a11y design for seniors older web users web design for elderly website accessibility
y Hockey | HI asks for bids to host various Nationals By www.thehindu.com Published On :: Tue, 05 May 2020 22:53:48 +0530 State units can take part across age-groups Full Article Hockey
y The matter of photography in the Americas / Natalia Brizuela and Jodi Roberts ; with contributions by Lisa Blackmore, Amy Sara Carroll, Marianela D'Aprile, María Fernanda Domínguez, Heloisa Espada, Rachel Price, Diana Ruiz, Tatiane Santa Ro By library.mit.edu Published On :: Sun, 16 Feb 2020 06:00:01 EST Rotch Library - TR184.B75 2018 Full Article
y Design: the key concepts / D.J. Huppatz By library.mit.edu Published On :: Sun, 16 Feb 2020 06:00:01 EST Barker Library - NK1510.H87 2019 Full Article
y Library of light: encounters with artists and designers / Jo Joelson By library.mit.edu Published On :: Sun, 16 Feb 2020 06:00:01 EST Rotch Library - N8219.L5 J64 2019 Full Article
y The women of Atelier 17: modernist printmaking in midcentury New York / Christina Weyl By library.mit.edu Published On :: Sun, 16 Feb 2020 06:00:01 EST Rotch Library - NE538.N5 W49 2019 Full Article
y Huguette Caland / edited by Anne Barlow, Sara Matson and Giles Jackson ; texts by Anne Barlow, Brigitte Caland and Negar Azimi By library.mit.edu Published On :: Sun, 16 Feb 2020 06:00:01 EST Rotch Library - N6537.C329 A4 2019 Full Article
y Legacy of the masters: painting and calligraphy of the Islamic world from the Shavleyan family collection / Will Kwiatkowski ; with contributions by John Seyller By library.mit.edu Published On :: Sun, 16 Feb 2020 06:00:01 EST Rotch Library - N6260.K87 2019 Full Article
y Usṭūrahʹhā va namādʹhā-yi āyinī dar nigārahʹhā-yi Saqānifārʹhā-yi Māzandarān / taʼlīf va gurdʹāvarī-i Muṣṭafá Rustamī, Fāṭimah Bābājānʹtabār Nashlī By library.mit.edu Published On :: Sun, 16 Feb 2020 06:00:01 EST Rotch Library - N7280.R888 2018 Full Article
y For your pleasure: Johannes Brus, photoworks and sculptures / with an essay by Clément Chéroux By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N6888.B745 A4 2018 Full Article
y Bauhaus imaginista: a school in the world / edited by Marion von Osten and Grant Watson By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N332.G33 B42724 2019 Full Article
y Anna Maria Maiolino, Entre pausas / texts by Anna Maria Maiolino, Tania Rivera and Randy Kennedy By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - NC200.M27 A4 2018 Full Article
y Leonardo da Vinci: nature and architecture / edited by Constance Moffatt, Sara Taglialagamba By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N6923.L33 M64 2019 Full Article
y Djordje Ozbolt: regaining memory loss / exhibition curator, Nicoletta Lambertucci By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N6488.I8 V433 2019 Y8 Full Article
y New design, neoplasticism: Nieuwe beelding / Piet Mondrian ; English translation by Harry Holtzman and Martin S. James By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N6948.5.D42 M6613 2019 Full Article
y Arnaud Vasseux: pièces non balayées. By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - NB553.V37 A4 2018 Full Article
y Gordon Parks: the new tide, early work, 1940-1950 / Philip Brookman ; with essays by Maurice Berger, Sarah Lewis, Richard J. Powell, Deborah Willis ; series editor, Peter W. Kunhardt, Jr By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - TR647.P37 2018 Full Article
y Heirloom / Larissa Sansour ; text by Nat Muller By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N6488.I8 V433 2019 D4 Full Article
y Art for people's sake: artists and community in Black Chicago, 1965-1975 / Rebecca Zorach By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - NX512.3.A35 Z67 2019 Full Article
y I have forgotten the night / Joël Andrianomearisoa ; curated by Rina Ralay Ranaivo and Emmanuel Daydé By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N6488.I8 V433 2019 M28 Full Article
y Herbst im paradies: The autumn of paradise / Jean-Luc Mylayne By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - TR729.B5 H47 2018 Full Article
y It's about time: Pavilion of Applied Arts / curator, Ralph Rugoff ; artist, Marysia Lewandowska By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N6488.I8 V433 2019 A67 Full Article
y Failed images: photography and its counter-practices / Ernst van Alphen By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - TR183.A47 2018 Full Article
y Fields of fungus and sunflowers / [edited and designed by Tammy Nguyen ; contributions by Lovely Umayam and Adriel Luis] By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N7433.35.U6 M37 no.6 Full Article
y Land, sand, strand: activation manual / drawings by Suki Seokyeong Kang By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N6488.I8 V433 2019 K6 Full Article
y Altered states: Substanzen in der zeitgenössischen Kunst = substances in contemporary art / herausgegeben von = edited by Milena Mercer ; Texte = texts, Max Daly ... [and thirteen others] By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N8251.S555 A48 2018 Full Article
y Panos Charalambous, Eva Stefani, Zafos Xagoraris / curated by Katerina Tselou By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N6488.I8 V433 2019 G8 Full Article
y Women, art and money in late Victorian and Edwardian England: the hustle and the scramble / Maria Quirk By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N8354.Q57 2019 Full Article
y Design by accident: for a new history of design / Alexandra Midal By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - NK1175.M53 2019 Full Article