Lab Chip, 2020, 20,1418-1425
DOI: 10.1039/D0LC00149J, Paper

Chun-Miao Xu, Man Tang, Jiao Feng, Hou-Fu Xia, Ling-Ling Wu, Dai-Wen Pang, Gang Chen, Zhi-Ling Zhang
A system integrating diagnostic and therapeutic functions for cancer is presented using magnetically controlled microfluidics.
The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2020, 20,1441-1448
DOI: 10.1039/D0LC00028K, Paper

Open Access

  This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Yoshiki Soda, Kye J. Robinson, Thomas J. Cherubini, Eric Bakker
A pixel-level colorimetric absorbance analysis can measure the total quantity of dye on paper, irrespective of shape and size.
The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2020, 20,1449-1460
DOI: 10.1039/C9LC01220F, Paper

Ronny Frank, Christoph Prönnecke, Ronny Azendorf, Heinz-Georg Jahnke, Annette G. Beck-Sickinger, Andrea A. Robitzki
We developed a novel 96-well microtiter plate based bioelectrochemical platform with a vertical divided cell three-electrode architecture and a 96-multipotentiostat to perform fully parallelised bioelectrocatalytic screenings on redox enzymes.
The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2020, 20,1390-1397
DOI: 10.1039/D0LC00021C, Communication

Bo Wang, Ximiao Wen, Yan Cao, Shan Huang, Hoa A. Lam, Tingyi “Leo” Liu, Pei-Shan Chung, Harold G. Monbouquette, Pei-Yu Chiou, Nigel T. Maidment
PDMS thin-film transfer and enzyme microstamping enabled 3-in-1 Si/PDMS hybrid chemtrode for multi-analyte sensing and chemical delivery in vivo.
The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2020, 20,1398-1409
DOI: 10.1039/C9LC01103J, Paper

Open Access

  This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Kartik Totlani, Jan-Willem Hurkmans, Walter M. van Gulik, Michiel T. Kreutzer, Volkert van Steijn
We developed a microfluidic droplet on-demand (DoD) generator that enables the production of droplets with a volume solely governed by the geometry of the generator for a range of operating conditions.
The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2020, 20,1503-1512
DOI: 10.1039/D0LC00103A, Paper

Juan Hu, Xiangpeng Li, Robert L. Judd, Christopher J. Easley
High temporal resolution sampling and quantitative detection of glycerol secretion dynamics from adipose tissue using our automated, droplet-based microfluidic system.
The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2020, 20,1472-1492
DOI: 10.1039/C9LC01047E, Paper

Open Access

  This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Mark Schurdak, Lawrence Vernetti, Luke Bergenthal, Quinn K. Wolter, Tong Ying Shun, Sandra Karcher, D. Lansing Taylor, Albert Gough
The Microphysiology Systems Database (MPS) is a critical tool for the design, management, analysis, and sharing of MPS study data.
The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2020, 20,1318-1357
DOI: 10.1039/C9LC00775J, Critical Review

Open Access

  This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Masoud Madadelahi, Luis F. Acosta-Soto, Samira Hosseini, Sergio O. Martinez-Chapa, Marc J. Madou
This paper focuses on theory and computational modelling of lab-on-a-disc devices of relevance for novel applications discovery and optimal designs.
The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2020, Advance Article
DOI: 10.1039/D0LC00051E, Paper

Jinxin Zhang, Jessica H. Hartman, Chuyi Chen, Shujie Yang, Qi Li, Zhenhua Tian, Po-Hsun Huang, Lin Wang, Joel N. Meyer, Tony Jun Huang
Acoustofluidic sorting of Caenorhabditis elegans in a high throughput manner.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2020, Advance Article
DOI: 10.1039/C9LC01226E, Paper

Jia Liu, Guoyun Sun, Shih-Chung Wei, Song Guo, Weikang Nicholas Lin, Chia-Hung Chen
Nanoplasmon-enhanced drop screen is developed to measure single-cell multiple miRNAs with high sensitivity of 0.1 nM, addressing cell nucleocytoplasmic profile in a throughput ∼100 cells per minute.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2020, Advance Article
DOI: 10.1039/D0LC00254B, Paper

Azusa Shimizu, Wei Huang Goh, Shun Itai, Michinao Hashimoto, Shigenori Miura, Hiroaki Onoe
A perfusable and stretchable gelatin-based microfluidic system that can apply both simultaneous fluidic shear stress and stretch stress to in vitro endothelial 3D tissues is presented.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2020, Advance Article
DOI: 10.1039/C9LC01209E, Paper

Open Access

  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

J. A. Crowe, A. El-Tamer, D. Nagel, A. V. Koroleva, J. Madrid-Wolff, O. E. Olarte, S. Sokolovsky, E. Estevez-Priego, A.-A. Ludl, J. Soriano, P. Loza-Alvarez, B. N. Chichkov, E. J. Hill, H. R. Parri, E. U. Rafailov
We identified photopolymers for 2-photon polymerisation with biocompatibility for human iPSC-derived neural network development. Generation of microscale scaffold topologies enabled neurite guidance, demonstrating use in reproducing aligned networks.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2020, Advance Article
DOI: 10.1039/C9LC01192G, Paper

Roman Mikhaylov, Fangda Wu, Hanlin Wang, Aled Clayton, Chao Sun, Zhihua Xie, Dongfang Liang, Yinhua Dong, Fan Yuan, Despina Moschou, Zhenlin Wu, Ming Hong Shen, Jian Yang, Yongqing Fu, Zhiyong Yang, Christian Burton, Rachel J. Errington, Marie Wiltshire, Xin Yang
We demonstrate a novel SAW device fabrication technique by mechanically clamping interdigital electrodes (IDEs) on the printed circuit board (PCB) to a LiNbO₃ wafer. The novel PCB-SAW device is capable of performing all the functions of standard SAW devices.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2020, Advance Article
DOI: 10.1039/D0LC00263A, Paper

Jaime L. Korner, Elanna B. Stephenson, Katherine S. Elvira
A new type of pharmacokinetic compartment model using artificial cell membranes that predicts intestinal absorption three times more accurately than the current state of the art.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2020, Advance Article
DOI: 10.1039/D0LC00134A, Paper

Sayali Upasham, Shalini Prasad
SLOCK is a sweat based platform for monitoring circadian relevant biomarkers-cortisol and DHEA, using electrochemical detection modality.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2020, Advance Article
DOI: 10.1039/D0LC00059K, Paper

Open Access

  This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Christian G. M. van Dijk, Maarten M. Brandt, Nikolaos Poulis, Jonas Anten, Matthijs van der Moolen, Liana Kramer, Erik F. G. A. Homburg, Laura Louzao-Martinez, Jiayi Pei, Merle M. Krebber, Bas W. M. van Balkom, Petra de Graaf, Dirk J. Duncker, Marianne C. Verhaar, Regina Luttge, Caroline Cheng
We present a microfluidic vascular device. Vascular cells in a 3D-ECM environment support hemodynamic flow and enable monocyte interaction.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2020, Advance Article
DOI: 10.1039/D0LC00302F, Paper

Christopher Dixon, Julian Lamanna, Aaron R. Wheeler
The integration of 3D porous membranes in a digital microfluidic device enables the generation of cell-free plasma from finger-stick volumes of blood with in-line, on-chip analysis.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2020, Advance Article
DOI: 10.1039/D0LC90036B, Correction

Open Access

  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Ewa Guzniczak, Oliver Otto, Graeme Whyte, Nicholas Willoughby, Melanie Jimenez, Helen Bridle
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2020, Advance Article
DOI: 10.1039/D0LC00069H, Paper

W. Hampton Henley, Nathan A. Siegfried, J. Michael Ramsey
Encoded beads carrying primer pairs for nucleic acid targets are used for sample preparation and multiplexed-in-space digital PCR quantification.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2020, Advance Article
DOI: 10.1039/D0LC00079E, Paper

Kenji Akama, Hiroyuki Noji
Homogeneous digital immunoassay is a powerful analytical method for highly sensitive biomarker detection with a simple protocol. By using this method, we demonstrated the simultaneous multiple protein detection.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2020, Advance Article
DOI: 10.1039/C9LC01064E, Paper

Seungbeom Noh, Hanseup Kim
This paper reports in-air monitoring of in vitro monolayer cells under air-exposure utilizing electrochemical impedance spectroscopy (EIS).
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2020, Advance Article
DOI: 10.1039/D0LC00318B, Paper

Ren Shen, Yanwei Jia, Pui-In Mak, Rui P. Martins
A proposed DNA amplification enhancer with a “clip-to-release on amplification” mechanism reduces dye-mediated inhibition to amplification, increases fluorescence signal up to 10-fold, and eliminates false-negative results for on-chip PCR.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2020, Advance Article
DOI: 10.1039/D0LC00213E, Paper

Open Access

  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Ioannis Lignos, Hendrik Utzat, Moungi G. Bawendi, Klavs F. Jensen
We present a flow-based system coupled with an optical interferometry setup for the extraction of single nanocrystal properties.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2020, Advance Article
DOI: 10.1039/D0LC00175A, Paper

Open Access

  This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Karl Olofsson, Björn Hammarström, Martin Wiklund
A novel, simple and robust route for binary separation of viable and dead cells using a density modified medium which takes advantage of the compromised cell membrane of dead cells.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2020, Advance Article
DOI: 10.1039/D0LC00280A, Communication

Amin Mansoorifar, Anthony Tahayeri, Luiz E. Bertassoni
We proposed a novel concept for reconfiguration of hydrogel microfluidic devices, where multiple fluidic pathways could be generated via reversible manipulation of magnetic inks.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2020, Accepted Manuscript
DOI: 10.1039/D0LC00250J, Paper

Yuexiao Song, Feng Xin, Yongsheng Xu
This work develops a reliable method to achieve stratified flow in squared cross-section microchannels by endowing the four channel walls with very different wettabilities. The gas–liquid flows are studied experimentally...
The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2020, 20,1628-1638
DOI: 10.1039/C9LC01165J, Paper

Jose A. Wippold, Han Wang, Joseph Tingling, Julian L. Leibowitz, Paul de Figueiredo, Arum Han
Identifying antibodies (Abs) that neutralize infectious agents is the first step for developing therapeutics, vaccines, and diagnostic tools for these infectious agents.
The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2020, 20,1577-1585
DOI: 10.1039/D0LC00024H, Paper

Jingjing Guo, Li Lin, Kaifeng Zhao, Yanling Song, Mengjiao Huang, Zhi Zhu, Leiji Zhou, Chaoyong Yang
An automated ligand binding affinity evaluation platform using digital microfluidics with a bidirectional magnetic separation method that reduces the bead loss.
The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2020, 20,1601-1611
DOI: 10.1039/D0LC00115E, Paper

Veasna Soum, Sooyong Park, Albertus Ivan Brilian, Jae-Youl Choi, Yongwoo Lee, Wonjung Kim, Oh-Sun Kwon, Kwanwoo Shin
A precise, simple, and inexpensive method for controlling fluid flow in a photo-paper-based microfluidic device was reported.
The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2020, 20,1687-1693
DOI: 10.1039/C9LC01021A, Paper

Zongdai Liu, Dan Luo, Kun-Lin Yang
The concentration of toluene vapor is obtained based on polymer-stabilized liquid crystals by viewing a colourful gamut under a polarized optical microscope.
The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2020, 20,1562-1576
DOI: 10.1039/D0LC00121J, Paper

Open Access

  This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Nicola Di Trani, Antonia Silvestri, Antons Sizovs, Yu Wang, Donald R. Erm, Danilo Demarchi, Xuewu Liu, Alessandro Grattoni
Control of molecular diffusion through nanofluidic channels using electrostatic gating.
The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2020, 20,1648-1657
DOI: 10.1039/D0LC00276C, Paper

Charuksha Walgama, Michael P. Nguyen, Lisa M. Boatner, Ian Richards, Richard M. Crooks
A hybrid paper/plastic microfluidic device for detection of Ag nanoparticle labels at concentrations as low as 12 pM.
The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2020, 20,1658-1675
DOI: 10.1039/C9LC00811J, Paper

A. D. Rodriguez, L. F. Horowitz, K. Castro, H. Kenerson, N. Bhattacharjee, G. Gandhe, A. Raman, R. J. Monnat, R. Yeung, R. C. Rostomily, A. Folch
We have developed a digitally-manufacturable microfluidic platform that allows for multiplexed drug testing of intact tumor slices.
The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2020, 20,1586-1600
DOI: 10.1039/D0LC00099J, Paper

Karina M. Lugo-Cintrón, José M. Ayuso, Bridget R. White, Paul M. Harari, Suzanne M. Ponik, David J. Beebe, Max M. Gong, María Virumbrales-Muñoz
Lymphatic organotypic in vitro model allows the examination of components of the tumor microenvironment (e.g., ECM density, cancer cells) in lymphatic vessel biology in the context of cancer, providing insights into potential therapeutic targets.
The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2020, 20,1554-1561
DOI: 10.1039/D0LC00063A, Communication

Nianzuo Yu, Yongshun Liu, Bai Ji, Shuli Wang, Yunyun Chen, Tianmeng Sun, Junhu Zhang, Bai Yang
Blood pressure sensors are proposed to measure the value of central venous pressure, and diagnose the severity of hypertension, hypotension and arterial thrombosis.
The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2020, Advance Article
DOI: 10.1039/C9LC00999J, Paper

Open Access

  This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

A. Link, T. Franke
Novel microfluidic platform to determine the viscoelastic fingerprint of a red blood cell population using surface acoustic waves.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2020, Accepted Manuscript
DOI: 10.1039/D0LC00153H, Paper

Zhening Su, Jinxu He, Peipei Zhou, Lu Huang, Jianhua Zhou
Crystallization of active pharmaceutical ingredients (APIs) is a crucial process in the pharmaceutical industry due to its great impact in drug efficacy. However, conventional approaches for screening the optimal crystallization...
The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2020, Advance Article
DOI: 10.1039/D0LC00142B, Paper

Sharif M. Rahman, Joshua M. Campbell, Rachael N. Coates, Katie M. Render, C. Ethan Byrne, Elizabeth C. Martin, Adam T. Melvin
Breast cancer cells co-cultured with adipose-derived stem cells (ASCs) in a microfluidic device exhibited enhanced growth, a more aggressive morphology and polarization towards the ASCs, and increased drug resistance.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2020, Accepted Manuscript
DOI: 10.1039/D0LC00096E, Paper

Hanfei Shen, Tony Liu, Jesse Cui, Piyush Borole, Ari Benjamin, Konrad Kording, David Issadore
Liquid biopsy (LB) technologies continue to improve in sensitivity, specificity, and multiplexing and can measure an ever growing library of disease biomarkers. However, clinical interpretation of the increasingly large sets...
The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2020, Accepted Manuscript
DOI: 10.1039/D0LC00300J, Paper

Asmaa Khater, Osama Abdelrehim, Mehdi Mohammadi, Milad Azarmanesh, Mohsen Jonmaleki, Razieh Salahandish, AbdulMajeed Mohamad, Amir Sanati Nezhad
Droplet microfluidics has provided lab-on-a-chip platforms with the capability of bacteria encapsulation in biomaterials, controlled culture environment, and live monitoring of growth and proliferation. The droplets are mainly generated from...
The content of this RSS Feed (c) The Royal Society of Chemistry