an Proteomic analysis of the S. cerevisiae response to the anticancer ruthenium complex KP1019 By feeds.rsc.org Published On :: Metallomics, 2020, Advance ArticleDOI: 10.1039/D0MT00008F, Paper Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Laura K. Stultz, Alexandra Hunsucker, Sydney Middleton, Evan Grovenstein, Jacob O’Leary, Eliot Blatt, Mary Miller, James Mobley, Pamela K. HansonProteomic analysis reveals that the anticancer ruthenium KP1019 induces proteotoxic, genotoxic, and oxidative stress responses in Saccharomyces cerevisiae.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
an Defining the mechanism of the mitochondrial Atm1p [2Fe–2S] cluster exporter By feeds.rsc.org Published On :: Metallomics, 2020, Advance ArticleDOI: 10.1039/C9MT00286C, PaperStephen A. Pearson, Christine Wachnowsky, J. A. CowanAtm1p mediated mitochondrial Fe–S cluster export is investigated, providing support for a [2Fe–2S](GS)4 cluster as a physiological substrate. A detailed mechanism of cluster export, combining kinetic, thermodynamic, and structural data is presented.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
an The first copper(II) complex with 1,10-phenanthroline and salubrinal with interesting biochemical properties By feeds.rsc.org Published On :: Metallomics, 2020, Advance ArticleDOI: 10.1039/D0MT00006J, PaperSebastiano Masuri, Enzo Cadoni, Maria Grazia Cabiddu, Francesco Isaia, Maria Giovanna Demuru, Lukáš Moráň, David Buček, Petr Vaňhara, Josef Havel, Tiziana PivettaThe novel complex Cu(phen)2(salubrinal)(ClO4)2 shows high free radical scavenging activity and good cytotoxic activity and induces cell death through ER-stress.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
an Gold(III) bis(dithiolene) complexes: from molecular conductors to prospective anticancer, antimicrobial and antiplasmodial agents By feeds.rsc.org Published On :: Metallomics, 2020, Accepted ManuscriptDOI: 10.1039/D0MT00064G, PaperDiana Fontinha, Silvia Andreia Sousa, Tânia S. Morais, Miguel Prudêncio, Jorge Leitão, Yann Le Gal, Dominique Lorcy, Rafaela Silva, Mariana Velho, Dulce Belo, Manuel Almeida, Joana Guerreiro, Teresa Pinheiro, Fernanda M. MarquesThe anticancer, antimicrobial and antiplasmodial activities of six gold(III) bis(dithiolene) complexes were studied. Complexes (1-6) showed relevant anticancer properties against A2780/A2780cisR ovarian cancer cells (IC50 values of 0.08-2 µM), also...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
an Enantiomeric Copper Based Anticancer Agents Promoting Sequence-Selective Cleavage of G-Quadruplex Telomeric DNA and non-random cleavage of plasmid DNA By feeds.rsc.org Published On :: Metallomics, 2020, Accepted ManuscriptDOI: 10.1039/D0MT00084A, PaperSabiha Parveen, J. A. Cowan, Zhen Yu, Farukh ArjmandCopper-based binuclear enantiomeric complexes 1S and 1R were synthesized as anticancer chemotherapeutic agents to target G-quadruplex rich region of DNA and thoroughly characterized by various spectroscopic and single X-ray crystal...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
an Bis(ethylmaltolato)oxidovanadium(IV) inhibited the pathogenesis of Alzheimer's disease in triple transgenic model mice By feeds.rsc.org Published On :: Metallomics, 2020, 12,474-490DOI: 10.1039/C9MT00271E, PaperZhijun He, Shuangxue Han, Chong Wu, Lina Liu, Huazhang Zhu, Ang Liu, Qiying Lu, Jingqiang Huang, Xiubo Du, Nan Li, Qinguo Xie, Lu Wan, Jiazuan Ni, Lingling Chen, Xiaogai Yang, Qiong LiuBEOV activates PPARγ to affect JAK2/STAT3/SOCS1 signaling and eventually prevents Aβ generation. Meanwhile, BEOV inactivates PTP1B to affect PI3K/Akt/GSK3β signaling and finally reduces tau hyperphosphorylation.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
an Chiral Ru(II) complexes act as a potential non-viral gene carrier for directional transportation to the nucleus and cytoplasm By feeds.rsc.org Published On :: Metallomics, 2020, 12,504-513DOI: 10.1039/C9MT00192A, PaperQiong Wu, Shuang-Yan Zhang, Si-Yan Liao, Jie-Qiong Cao, Wen-Jie Zheng, Li Li, Wen-Jie MeiA novel approach has been proposed to develop a potent gene carrier system for enantioselectivity on the self-assembly of G-quadruplex DNA promoted by chiral Ru(II) complexes, and the different assembled nanostructures of cellular uptake to the nucleus and cytoplasm.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
an Gene expression in mouse muscle over time after nickel pellet implantation By feeds.rsc.org Published On :: Metallomics, 2020, 12,528-538DOI: 10.1039/C9MT00289H, PaperDesmond I. Bannon, Wenjun Bao, Stephen D. Turner, Wilfred C. McCain, William Dennis, Russ Wolfinger, Ed Perkins, Roger AbounaderImplanted nickel becomes toxic when it exceeds homeostasis, initiating a range of global gene effects over time, including oxidative phosphorylation and immune responses, which are impacted in opposite directions.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
an Distribution and chemical form of selenium in Neptunia amplexicaulis from Central Queensland, Australia By feeds.rsc.org Published On :: Metallomics, 2020, 12,514-527DOI: 10.1039/C9MT00244H, PaperMaggie-Anne Harvey, Peter D. Erskine, Hugh H. Harris, Gillian K. Brown, Elizabeth A. H. Pilon-Smits, Lachlan W. Casey, Guillaume Echevarria, Antony van der EntElemental mapping of selenium in the hyperaccumulator Neptunia amplexicaulis determined whole plant and tissue level selenium distribution. The total concentrations and chemical forms of selenium are also reported for this species.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
an Lanthanum chloride impairs spatial learning and memory by inducing [Ca2+]m overload, mitochondrial fission–fusion disorder and excessive mitophagy in hippocampal nerve cells of rats By feeds.rsc.org Published On :: Metallomics, 2020, 12,592-606DOI: 10.1039/C9MT00291J, PaperMiao Yu, Jinghua Yang, Xiang Gao, Wenchang Sun, Shiyu Liu, Yarao Han, Xiaobo Lu, Cuihong Jin, Shengwen Wu, Yuan CaiLanthanum chloride damages hippocampal nerve cells of rats through inducing [Ca2+]m overload, mitochondrial fission–fusion disorder, and excessive mitophagy.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
an Heterobimetallic Ru(II)/Fe(II) complexes as potent anticancer agents against breast cancer cells, inducing apoptosis through multiple targets By feeds.rsc.org Published On :: Metallomics, 2020, 12,547-561DOI: 10.1039/C9MT00272C, PaperAdriana Pereira Mundim Guedes, Francyelli Mello-Andrade, Wanessa Carvalho Pires, Maria Alice Montes de Sousa, Paula Francinete Faustino da Silva, Mariana S. de Camargo, Hendryk Gemeiner, Menegário A. Amauri, Clever Gomes Cardoso, Paulo Roberto de Melo Reis, Elisângela de Paula Silveira-Lacerda, Alzir A. BatistaAntimetastatic activity, high selectivity and cytotoxicity for human tumor cell lines make ruthenium(II) complexes attractive for the development of new chemotherapeutic agents for cancer treatment.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
an Copper accumulation and the effect of chelation treatment on cerebral amyloid angiopathy compared to parenchymal amyloid plaques By feeds.rsc.org Published On :: Metallomics, 2020, 12,539-546DOI: 10.1039/C9MT00306A, PaperXiayoue Zhu, Tiffany W. Victor, Ashwin Ambi, Joseph K. Sullivan, Joshua Hatfield, Feng Xu, Lisa M. Miller, William E. Van NostrandMultimodal imaging studies show that Aβ amyloid in brain vessels of Tg2576 mice (green) preferentially binds copper (red) – a pathology that can be reduced with copper chelators.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
an The role of necroptosis and apoptosis through the oxidative stress pathway in the liver of selenium-deficient swine By feeds.rsc.org Published On :: Metallomics, 2020, 12,607-616DOI: 10.1039/C9MT00295B, PaperYuan Zhang, Dahai Yu, Jiuli Zhang, Jun Bao, Chaohua Tang, Ziwei ZhangNecroptosis is regarded as a new paradigm of cell death that plays a key role in the liver damage observed with selenium (Se) deficiency.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
an Multi-genomic analysis of the cation diffusion facilitator transporters from algae By feeds.rsc.org Published On :: Metallomics, 2020, 12,617-630DOI: 10.1039/D0MT00009D, PaperAniefon Ibuot, Andrew P. Dean, Jon K. PittmanCation diffusion facilitator metal transporters are widespread throughout algae and include a novel algal-specific clade. Functional analysis of Chlamydomonas reinhardtii isoforms partly validated phylogenetic prediction of substrate specificity.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
an Correction: Bis(ethylmaltolato)oxidovanadium(IV) inhibited the pathogenesis of Alzheimer's disease in triple transgenic model mice By feeds.rsc.org Published On :: Metallomics, 2020, 12,631-631DOI: 10.1039/D0MT90008G, Correction Open Access This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Zhijun He, Shuangxue Han, Chong Wu, Lina Liu, Huazhang Zhu, Ang Liu, Qiying Lu, Jingqiang Huang, Xiubo Du, Nan Li, Qingguo Xie, Lu Wan, Jiazuan Ni, Lingling Chen, Xiaogai Yang, Qiong LiuThe content of this RSS Feed (c) The Royal Society of Chemistry Full Article
an Ruthenium(III) complexes containing thiazole-based ligands that modulate amyloid-β aggregation By feeds.rsc.org Published On :: Metallomics, 2020, 12,491-503DOI: 10.1039/D0MT00054J, PaperSamantha E. Huffman, Gideon K. Yawson, Samuel S. Fisher, Paige J. Bothwell, David C. Platt, Marjorie A. Jones, Christopher G. Hamaker, Michael I. WebbAlzheimer's Disease (AD) is a devastating neurodegenerative disorder where one of the commonly observed pathological hallmarks is extracellular deposits of the peptide amyloid-β (Aβ).The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
an Correction: Identification and determination of selenocysteine, selenosugar, and other selenometabolites in turkey liver By feeds.rsc.org Published On :: Metallomics, 2020, Advance ArticleDOI: 10.1039/D0MT90015J, Correction Open Access This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Katarzyna Bierla, Rachel M. Taylor, Joanna Szpunar, Ryszard Lobinski, Roger A. SundeTo cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
an Investigation of the impact of magnesium versus titanium implants on protein composition in osteoblast by label free quantification By feeds.rsc.org Published On :: Metallomics, 2020, Advance ArticleDOI: 10.1039/D0MT00028K, Paper Open Access This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.M. Omidi, N. Ahmad Agha, A. Müller, F. Feyerabend, H. Helmholz, R. Willumeit-Römer, H. Schlüter, B. J. C. Luthringer-FeyerabendTo our knowledge, this is the first report describing and comparing the effects of magnesium and titanium biomaterials on human osteoblast proteome.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
an Diphenyl Diselenide Protects Caenorhabditis elegans Model for Huntington's Disease by Activation of Antioxidant Pathway and Decrease in Protein Aggregation By feeds.rsc.org Published On :: Metallomics, 2020, Accepted ManuscriptDOI: 10.1039/D0MT00074D, PaperFabiane Bicca Obetine Baptista, Marina Lopes Machado, Aline da Silva Franzen, Larissa Marafiga Cordeiro, Tassia da Silveira, Leticia Arantes, Félix A. A. SoaresHuntington’s disease (HD) is an autosomal dominant, progressive neurodegenerative disease with a distinct phenotype. It occurs due to a mutation in huntingtin (or IT19) gene with abnormal CAG repeat, leading...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
an A liver-targeting Cu(I) chelator relocates Cu in hepatocytes and promotes Cu excretion in a murine model of Wilson’s disease By feeds.rsc.org Published On :: Metallomics, 2020, Accepted ManuscriptDOI: 10.1039/D0MT00069H, PaperMarie Monestier, AnaÏS M. Pujol, Aline Lamboux, Martine Cuillel, Isabelle Pignot-Paintrand, Doris Cassio, Peggy Charbonnier, Khémary Um, Amélie Harel, Sylvain BOHIC, Christelle GATEAU, Vincent Balter, Virginie Brun, Pascale Delangle, Elisabeth MintzCopper chelation is the most commonly used therapeutic strategy nowadays to treat Wilson’s disease, a genetic disorder primarily inducing a pathological accumulation of Cu in the liver. The mechanism of...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
an Linc-ROR promotes arsenite-transformed keratinocyte proliferation by inhibiting P53 activity By feeds.rsc.org Published On :: Metallomics, 2020, Advance ArticleDOI: 10.1039/D0MT00076K, PaperXinyang Li, Chao Zuo, Mei Wu, Zunzhen ZhangLinc-ROR modulates the cell proliferation in arsenite-transformed keratinocytes via inhibiting P53 activity through the PI3K/AKT pathway.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
an Evidence that levels of nine essential metals in post-mortem human-Alzheimer's-brain and ex vivo rat-brain tissues are unaffected by differences in post-mortem delay, age, disease staging, and brain bank location By feeds.rsc.org Published On :: Metallomics, 2020, Advance ArticleDOI: 10.1039/D0MT00048E, PaperMelissa Scholefield, Stephanie J. Church, Jingshu Xu, Sarah Kassab, Natalie J. Gardiner, Federico Roncaroli, Nigel M. Hooper, Richard D. Unwin, Garth J. S. CooperMetal findings in human Alzheimer brains are consistent despite differences in sample post-mortem delay, age, Braak stage and biobank location.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
an In vitro selenium supplementation suppresses key mediators involved in myometrial activation and rupture of fetal membranes By feeds.rsc.org Published On :: Metallomics, 2020, Advance ArticleDOI: 10.1039/D0MT00063A, PaperDineli Matheesha Kalansuriya, Ratana Lim, Martha LappasSelenium suppresses key mediators involved in preterm birth in human fetal membranes and myometrium.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
an History and Imperialism: Writings, 1963-1986 By www.wiley.com Published On :: 2020-02-26T05:00:00Z Writings on History brings together a selection of texts by Louis Althusser dating from 1963 to 1986, including essays, a lecture, notes to his collaborators, and the transcript of an informal 1963 discussion of literary history. The centrepiece of this collection is Althusser’s previously unpublished Book on Imperialism, a theorization of globalized capitalism that remained unfinished. All these writings are concerned with the place of history in Read More... Full Article
an History and Imperialism: Writings, 1963-1986 By www.wiley.com Published On :: 2020-02-26T05:00:00Z Writings on History brings together a selection of texts by Louis Althusser dating from 1963 to 1986, including essays, a lecture, notes to his collaborators, and the transcript of an informal 1963 discussion of literary history. The centrepiece of this collection is Althusser’s previously unpublished Book on Imperialism, a theorization of globalized capitalism that remained unfinished. All these writings are concerned with the place of history in Read More... Full Article
an A Companion to the Harlem Renaissance By www.wiley.com Published On :: 2020-04-13T04:00:00Z A Companion to the Harlem Renaissance presents a comprehensive collection of original essays that address the literature and culture of the Harlem Renaissance from the end of World War I to the middle of the 1930s. Read More... Full Article
an What is Literature?: A Critical Anthology By www.wiley.com Published On :: 2020-04-13T04:00:00Z An essential guide to understanding literary theory and criticism in the European traditionWhat is Literature? A Critical Anthology explores the most fundamental question in literary studies. ‘What is literature?’ is the name of a problem that emerges with the idea of literature in European modernity. This volume offers a cross-section of modern literary theory and reflects on the history of thinking about literature as a specific form. Read More... Full Article
an Reacher Said Nothing: Lee Child and the Making of Make Me By www.wiley.com Published On :: 2020-04-14T04:00:00Z It had never been attempted before, and might never be done again. One man watching another man write a novel from beginning to end. On September 1, 2014, in an 11th floor apartment in New York, Lee Child embarked on the twentieth book in his globally successful Jack Reacher series. Andy Martin was there to see him do it, sitting a couple of yards behind him, peering over his shoulder as the writer took another drag of a Camel cigarette and tapped Read More... Full Article
an Reacher Said Nothing: Lee Child and the Making of Make Me By www.wiley.com Published On :: 2020-04-14T04:00:00Z It had never been attempted before, and might never be done again. One man watching another man write a novel from beginning to end. On September 1, 2014, in an 11th floor apartment in New York, Lee Child embarked on the twentieth book in his globally successful Jack Reacher series. Andy Martin was there to see him do it, sitting a couple of yards behind him, peering over his shoulder as the writer took another drag of a Camel cigarette and tapped Read More... Full Article
an IRCS State branch: observes World Red cross Day By Published On :: IRCS State branch: observes World Red cross Day Full Article
an Quarantine centres for two ACs set up By Published On :: Quarantine centres for two ACs set up Full Article
an IMC initiates cleanliness drive: at temporary market sites By Published On :: IMC initiates cleanliness drive: at temporary market sites Full Article
an TSE proprietor extends helping hand to widows, differently abled persons By Published On :: TSE proprietor extends helping hand to widows, differently abled persons Full Article
an Dr S Ranjan provides relief material again By Published On :: Dr S Ranjan provides relief material again Full Article
an Letpao flags off buses for stranded people By Published On :: Letpao flags off buses for stranded people Full Article
an Kangpokpi asks passenger vehicles not to stop midway By Published On :: Kangpokpi asks passenger vehicles not to stop midway Full Article
an Speaker inspects quarantine centre By Published On :: Speaker inspects quarantine centre Full Article
an Lack of man power dwarfs efforts at Mao Gate By Published On :: Lack of man power dwarfs efforts at Mao Gate Full Article
an Chess Online Nations Cup | Anand’s 17-move stunner in India’s 2-2 draw against Russia By www.thehindu.com Published On :: Fri, 08 May 2020 14:02:10 +0530 Viswanathan Anand, after four well-played draws, brought down Russia No. 1 Ian Nepomniachtchi in just 17 moves and then had USA’s Hikaru Nakamura on the run in their drawn encounter. Full Article Other Sports
an [ASAP] In Vitro Identification of the Hamiltonian Cycle Using a Circular Structure Assisted DNA Computer By feedproxy.google.com Published On :: Mon, 06 Apr 2020 04:00:00 GMT ACS Combinatorial ScienceDOI: 10.1021/acscombsci.9b00150 Full Article
an [ASAP] Development of Mischmetal–Fe–Co–B Permanent Magnet Alloys via High-Throughput Methods By feedproxy.google.com Published On :: Mon, 06 Apr 2020 04:00:00 GMT ACS Combinatorial ScienceDOI: 10.1021/acscombsci.9b00190 Full Article
an [ASAP] Ce(OTf)<sub>3</sub>-Catalyzed Multicomponent Reaction of Alkynyl Carboxylic Acids, <italic toggle="yes">tert</italic>-Butyl Isocyanide, and Azides for the Assembly of Triazole–Oxazole Derivatives By feedproxy.google.com Published On :: Mon, 20 Apr 2020 04:00:00 GMT ACS Combinatorial ScienceDOI: 10.1021/acscombsci.0c00012 Full Article
an [ASAP] Immobilized Carbodiimide Assisted Flow Combinatorial Protocol to Facilitate Amide Coupling and Lactamization By feedproxy.google.com Published On :: Wed, 22 Apr 2020 04:00:00 GMT ACS Combinatorial ScienceDOI: 10.1021/acscombsci.0c00001 Full Article
an [ASAP] Update to Our Reader, Reviewer, and Author Communities—April 2020 By feedproxy.google.com Published On :: Wed, 22 Apr 2020 04:00:00 GMT ACS Combinatorial ScienceDOI: 10.1021/acscombsci.0c00061 Full Article
an [ASAP] Optimized Multimetal Sensitized Phosphor for Enhanced Red Up-Conversion Luminescence by Machine Learning By feedproxy.google.com Published On :: Sun, 26 Apr 2020 04:00:00 GMT ACS Combinatorial ScienceDOI: 10.1021/acscombsci.0c00035 Full Article
an [ASAP] Magnetic Bead-Immobilized Mammalian Cells Are Effective Targets to Enrich Ligand-Displaying Yeast By feedproxy.google.com Published On :: Mon, 27 Apr 2020 04:00:00 GMT ACS Combinatorial ScienceDOI: 10.1021/acscombsci.0c00036 Full Article
an [ASAP] Experimental and Theoretical Investigation on Phase Formation and Mechanical Properties in Cr–Co–Ni Alloys Processed Using a Novel Thin-Film Quenching Technique By feedproxy.google.com Published On :: Tue, 28 Apr 2020 04:00:00 GMT ACS Combinatorial ScienceDOI: 10.1021/acscombsci.9b00170 Full Article
an Annual Report to the Nation: Overall cancer mortality continues to decline; Special section on adults ages 20 to 49 shows higher cancer incidence and mortality for women than men By feedproxy.google.com Published On :: Thu, 30 May 2019 08:00:00 -0400 The 2019 Annual Report to the Nation on the Status of Cancer finds overall cancer death rates continue to decline and cancer incidence dropped in men and remained stable in women. A special section reports on recent cancer trends in younger adults. Full Article
