and

Health Tip: Understanding Measles

Title: Health Tip: Understanding Measles
Category: Health News
Created: 8/28/2019 12:00:00 AM
Last Editorial Review: 8/28/2019 12:00:00 AM




and

AHA News: Understanding Connection Between Poverty, Childhood Trauma and Heart Disease

Title: AHA News: Understanding Connection Between Poverty, Childhood Trauma and Heart Disease
Category: Health News
Created: 8/27/2019 12:00:00 AM
Last Editorial Review: 8/28/2019 12:00:00 AM




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Thousands of Kidneys Thrown Away by U.S. Transplant Centers

Title: Thousands of Kidneys Thrown Away by U.S. Transplant Centers
Category: Health News
Created: 8/27/2019 12:00:00 AM
Last Editorial Review: 8/28/2019 12:00:00 AM




and

Jumps in Pot Use, Depression and Drinking Threaten Gains Against Smoking

Title: Jumps in Pot Use, Depression and Drinking Threaten Gains Against Smoking
Category: Health News
Created: 8/28/2019 12:00:00 AM
Last Editorial Review: 8/29/2019 12:00:00 AM




and

Frequent Hand-Washing Tough on Those With Eczema

Title: Frequent Hand-Washing Tough on Those With Eczema
Category: Health News
Created: 8/21/2020 12:00:00 AM
Last Editorial Review: 8/24/2020 12:00:00 AM




and

Play It Safe With Allergies, Asthma During Pandemic School Year

Title: Play It Safe With Allergies, Asthma During Pandemic School Year
Category: Health News
Created: 8/21/2020 12:00:00 AM
Last Editorial Review: 8/24/2020 12:00:00 AM




and

Pandemic Drove Spike in Panic Attacks

Title: Pandemic Drove Spike in Panic Attacks
Category: Health News
Created: 8/24/2020 12:00:00 AM
Last Editorial Review: 8/25/2020 12:00:00 AM




and

Your Sleep Patterns and Alzheimer's Risk

Title: Your Sleep Patterns and Alzheimer's Risk
Category: Health News
Created: 8/24/2020 12:00:00 AM
Last Editorial Review: 8/25/2020 12:00:00 AM




and

Thousands of COVID Cases Already on College Campuses

Title: Thousands of COVID Cases Already on College Campuses
Category: Health News
Created: 8/26/2020 12:00:00 AM
Last Editorial Review: 8/26/2020 12:00:00 AM




and

Many Americans Struggling to Afford Health Care in Pandemic

Title: Many Americans Struggling to Afford Health Care in Pandemic
Category: Health News
Created: 8/25/2020 12:00:00 AM
Last Editorial Review: 8/26/2020 12:00:00 AM




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One Pandemic Silver Lining: Fewer Severe Asthma Attacks in Kids

Title: One Pandemic Silver Lining: Fewer Severe Asthma Attacks in Kids
Category: Health News
Created: 8/27/2020 12:00:00 AM
Last Editorial Review: 8/28/2020 12:00:00 AM




and

Pandemic Learning Can Strain Children's Eyes

Title: Pandemic Learning Can Strain Children's Eyes
Category: Health News
Created: 8/27/2020 12:00:00 AM
Last Editorial Review: 8/28/2020 12:00:00 AM




and

Cancer Radiation Can Safely Proceed During COVID-19 Pandemic: Study

Title: Cancer Radiation Can Safely Proceed During COVID-19 Pandemic: Study
Category: Health News
Created: 8/27/2020 12:00:00 AM
Last Editorial Review: 8/28/2020 12:00:00 AM




and

FDA Warns About Hand Sanitizers in Food-Like Packaging

Title: FDA Warns About Hand Sanitizers in Food-Like Packaging
Category: Health News
Created: 8/27/2020 12:00:00 AM
Last Editorial Review: 8/28/2020 12:00:00 AM




and

How Your Medicines Make Their Way Into Rivers, Lakes and Bays

Title: How Your Medicines Make Their Way Into Rivers, Lakes and Bays
Category: Health News
Created: 8/23/2021 12:00:00 AM
Last Editorial Review: 8/23/2021 12:00:00 AM




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AHA News: After Three Strokes, He 'Overheard' the Grim Prognosis and Fought Back

Title: AHA News: After Three Strokes, He 'Overheard' the Grim Prognosis and Fought Back
Category: Health News
Created: 8/20/2021 12:00:00 AM
Last Editorial Review: 8/23/2021 12:00:00 AM




and

No Change in Adolescent Drug, Alcohol Use During Pandemic

Title: No Change in Adolescent Drug, Alcohol Use During Pandemic
Category: Health News
Created: 8/24/2021 12:00:00 AM
Last Editorial Review: 8/24/2021 12:00:00 AM




and

Pandemic Tied to Rising Number of Fatal Opioid ODs

Title: Pandemic Tied to Rising Number of Fatal Opioid ODs
Category: Health News
Created: 8/24/2021 12:00:00 AM
Last Editorial Review: 8/24/2021 12:00:00 AM




and

Drinking at Home: Liquor Store Sales Rose During Pandemic

Title: Drinking at Home: Liquor Store Sales Rose During Pandemic
Category: Health News
Created: 8/24/2021 12:00:00 AM
Last Editorial Review: 8/24/2021 12:00:00 AM




and

Pentagon to Make COVID Vaccination Mandatory for Military

Title: Pentagon to Make COVID Vaccination Mandatory for Military
Category: Health News
Created: 8/23/2021 12:00:00 AM
Last Editorial Review: 8/24/2021 12:00:00 AM




and

Little Change in Number of Uninsured in Pandemic's First Year

Title: Little Change in Number of Uninsured in Pandemic's First Year
Category: Health News
Created: 8/23/2021 12:00:00 AM
Last Editorial Review: 8/24/2021 12:00:00 AM




and

Large-Scale Pandemics Aren't as Rare as You Think: Study

Title: Large-Scale Pandemics Aren't as Rare as You Think: Study
Category: Health News
Created: 8/25/2021 12:00:00 AM
Last Editorial Review: 8/25/2021 12:00:00 AM




and

Search for Coronavirus Origins at Standstill: WHO Team

Title: Search for Coronavirus Origins at Standstill: WHO Team
Category: Health News
Created: 8/26/2021 12:00:00 AM
Last Editorial Review: 8/26/2021 12:00:00 AM




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Record High COVID Cases and Deaths Reported in Florida

Title: Record High COVID Cases and Deaths Reported in Florida
Category: Health News
Created: 8/26/2021 12:00:00 AM
Last Editorial Review: 8/26/2021 12:00:00 AM




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Half of American Workers Support COVID Vaccination, Mask Mandates in Workplace

Title: Half of American Workers Support COVID Vaccination, Mask Mandates in Workplace
Category: Health News
Created: 8/27/2021 12:00:00 AM
Last Editorial Review: 8/27/2021 12:00:00 AM




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Fatal ODs From Illicit Tranquilizers Jumped 6-Fold During Pandemic

Title: Fatal ODs From Illicit Tranquilizers Jumped 6-Fold During Pandemic
Category: Health News
Created: 8/26/2021 12:00:00 AM
Last Editorial Review: 8/27/2021 12:00:00 AM




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AHA News: What Goes Into a Mediterranean Diet, and How to Get Started

Title: AHA News: What Goes Into a Mediterranean Diet, and How to Get Started
Category: Health News
Created: 8/23/2022 12:00:00 AM
Last Editorial Review: 8/23/2022 12:00:00 AM




and

Pandemic Brought More Woes for Kids Prone to Headaches

Title: Pandemic Brought More Woes for Kids Prone to Headaches
Category: Health News
Created: 8/9/2022 12:00:00 AM
Last Editorial Review: 8/10/2022 12:00:00 AM




and

How Long Do Potatoes Last? Raw, Cooked, and More

Title: How Long Do Potatoes Last? Raw, Cooked, and More
Category: Health and Living
Created: 8/26/2022 12:00:00 AM
Last Editorial Review: 8/26/2022 12:00:00 AM




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Insulin and Insulin Resistance: The Ultimate Guide

Title: Insulin and Insulin Resistance: The Ultimate Guide
Category: Health and Living
Created: 7/19/2022 12:00:00 AM
Last Editorial Review: 7/19/2022 12:00:00 AM




and

Qigong Meditation for Beginners: Techniques, Benefits, and More

Title: Qigong Meditation for Beginners: Techniques, Benefits, and More
Category: Health and Living
Created: 8/24/2022 12:00:00 AM
Last Editorial Review: 8/24/2022 12:00:00 AM




and

'News Addiction' Is Common and Can Harm Your Mental Health

Title: 'News Addiction' Is Common and Can Harm Your Mental Health
Category: Health News
Created: 8/24/2022 12:00:00 AM
Last Editorial Review: 8/25/2022 12:00:00 AM




and

People Underestimate Impact of Random Acts of Kindness

Title: People Underestimate Impact of Random Acts of Kindness
Category: Health News
Created: 8/24/2022 12:00:00 AM
Last Editorial Review: 8/25/2022 12:00:00 AM




and

Banded Squats: Benefits and 11 Ways to Do Them

Title: Banded Squats: Benefits and 11 Ways to Do Them
Category: Health and Living
Created: 8/8/2022 12:00:00 AM
Last Editorial Review: 8/8/2022 12:00:00 AM




and

As Pandemic Eases, It's Boom Times for Cosmetic Surgeons

Title: As Pandemic Eases, It's Boom Times for Cosmetic Surgeons
Category: Health News
Created: 8/24/2022 12:00:00 AM
Last Editorial Review: 8/24/2022 12:00:00 AM




and

Prostatitis (Inflammation of the Prostate Gland)

Title: Prostatitis (Inflammation of the Prostate Gland)
Category: Diseases and Conditions
Created: 12/31/1997 12:00:00 AM
Last Editorial Review: 7/29/2022 12:00:00 AM




and

Pets Have Helped People With HIV Through Two Pandemics

Title: Pets Have Helped People With HIV Through Two Pandemics
Category: Health News
Created: 6/23/2022 12:00:00 AM
Last Editorial Review: 6/23/2022 12:00:00 AM




and

HIV Testing Plummeted During Pandemic

Title: HIV Testing Plummeted During Pandemic
Category: Health News
Created: 6/27/2022 12:00:00 AM
Last Editorial Review: 6/27/2022 12:00:00 AM




and

Why is My Blood Pressure Suddenly High and Low?

Title: Why is My Blood Pressure Suddenly High and Low?
Category: Diseases and Conditions
Created: 7/6/2022 12:00:00 AM
Last Editorial Review: 7/6/2022 12:00:00 AM




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When Is Blood Pressure Lowest and Highest During the Day?

Title: When Is Blood Pressure Lowest and Highest During the Day?
Category: Diseases and Conditions
Created: 7/26/2022 12:00:00 AM
Last Editorial Review: 7/26/2022 12:00:00 AM




and

Scotland Becomes 1st Country to Provide Free Period Products

Title: Scotland Becomes 1st Country to Provide Free Period Products
Category: Health News
Created: 8/15/2022 12:00:00 AM
Last Editorial Review: 8/16/2022 12:00:00 AM




and

Your Brain Gets Tired, and Scientists Now Know Why

Title: Your Brain Gets Tired, and Scientists Now Know Why
Category: Health News
Created: 8/12/2022 12:00:00 AM
Last Editorial Review: 8/15/2022 12:00:00 AM




and

Yeast infections vs. STDs in Men and Women

Title: Yeast infections vs. STDs in Men and Women
Category: Diseases and Conditions
Created: 1/8/2020 12:00:00 AM
Last Editorial Review: 7/29/2022 12:00:00 AM




and

Salicylate Sensitivity Causes, Symptoms, and Foods to Avoid

Title: Salicylate Sensitivity Causes, Symptoms, and Foods to Avoid
Category: Health and Living
Created: 7/8/2022 12:00:00 AM
Last Editorial Review: 7/8/2022 12:00:00 AM




and

GERD (Acid Reflux) in Infants and Children

Title: GERD (Acid Reflux) in Infants and Children
Category: Diseases and Conditions
Created: 1/31/2005 12:00:00 AM
Last Editorial Review: 8/18/2022 12:00:00 AM




and

What Is the Main Cause of Leaky Gut, and How Do You Fix It?

Title: What Is the Main Cause of Leaky Gut, and How Do You Fix It?
Category: Diseases and Conditions
Created: 8/23/2022 12:00:00 AM
Last Editorial Review: 8/23/2022 12:00:00 AM




and

Treating central sleep apnoea in heart failure: is positive airway pressure and adaptive servo-ventilation in particular the gold standard?

Extract

We read with great interest the review article by Randerath et al. [1] recently published in the European Respiratory Review. We would like to congratulate the authors on this clearly structured review, which emphasises the urgent need for an increasingly differentiated view of central sleep apnoea (CSA) in the context of precision medicine.




and

The deadly dance of alveolar macrophages and influenza virus

Influenza A virus (IAV) is one of the leading causes of respiratory infections. The lack of efficient anti-influenza therapeutics requires a better understanding of how IAV interacts with host cells. Alveolar macrophages are tissue-specific macrophages that play a critical role in lung innate immunity and homeostasis, yet their role during influenza infection remains unclear. First, our review highlights an active IAV replication within alveolar macrophages, despite an abortive viral cycle. Such infection leads to persistent alveolar macrophage inflammation and diminished phagocytic function, alongside direct mitochondrial damage and indirect metabolic shifts in the alveolar micro-environment. We also discuss the "macrophage disappearance reaction", which is a drastic reduction of the alveolar macrophage population observed after influenza infection in mice but debated in humans, with unclear underlying mechanisms. Furthermore, we explore the dual nature of alveolar macrophage responses to IAV infection, questioning whether they are deleterious or protective for the host. While IAV may exploit immuno-evasion strategies and induce alveolar macrophage alteration or depletion, this could potentially reduce excessive inflammation and allow for the replacement of more effective cells. Despite these insights, the pathophysiological role of alveolar macrophages during IAV infection in humans remains understudied, urging further exploration to unravel their precise contributions to disease progression and resolution.




and

Impaired lung function and associated risk factors in children born prematurely: a systematic review and meta-analysis

Background

Immature lung development and respiratory morbidity place preterm-born children at high risk of long-term pulmonary sequelae. This systematic review and meta-analysis aims to quantify lung function in preterm-born children and identify risk factors for a compromised lung function.

Methods

We searched MEDLINE, Embase, Cochrane Library, Web of Science and Scopus for relevant studies published on preterm cohorts born since 1990. Studies comparing forced expiratory volume in 1 s (FEV1) in preterm-born children aged ≥5 years to term-born controls or normative data were included. Study quality was assessed using the Newcastle–Ottawa Scale for cohort studies. Standardised mean differences in FEV1 and secondary spirometry outcomes per study were pooled using meta-analysis. The impact of different demographic and neonatal variables on studies’ FEV1 effect sizes was investigated by meta-regression analyses. Certainty of evidence was assessed using the Grading of Recommendations, Assessment, Development, and Evaluations framework.

Results

We identified 42 studies with unique cohorts including 4743 preterm children and 9843 controls. Median gestational age in the studies was 28.0 weeks and age at assessment ranged from 6.7 to 16.7 years. Preterm children had lower FEV1 than controls (–0.58 sd, 95% CI –0.69– –0.47 sd, p<0.001) resulting in a relative risk of 2.9 (95% CI 2.4–3.4) for abnormal outcome, with high certainty of evidence. FEV1 was significantly associated with gestational age, birthweight, bronchopulmonary dysplasia and invasive mechanical ventilation in univariate meta-regression analyses (R2=36–96%).

Conclusion

This systematic review shows robust evidence of impaired lung function in preterm-born children with a high certainty of evidence.




and

Epidemiology of severe asthma in children: a systematic review and meta-analysis

Background

Severe asthma significantly impacts a minority of children with asthma, leading to frequent symptoms, hospitalisations and potential long-term health consequences. However, accurate global data on severe asthma epidemiology is lacking. This study aims to address this gap, providing data on severe asthma epidemiology, regional differences and associated comorbidities.

Methods

We conducted a rigorous systematic review and meta-analysis following a registered protocol (PROSPERO CRD42023472845). We searched PubMed, Scopus and Web of Science for cohort or cross-sectional studies published since 2003, evaluating severe asthma incidence and prevalence in children. Study quality and risk of bias were assessed using STROBE guidelines.

Results

Nine studies investigating European children with asthma (aged 5–18 years) were included in the meta-analysis. No significant publication bias was found. The overall severe asthma prevalence in children with asthma was 3% (95% CI 1–6; I2=99.9%; p<0.001), with no significant difference between males and females. Prevalence estimates varied significantly depending on the diagnostic criteria used (Global Initiative for Asthma: 6%; European Respiratory Society/American Thoracic Society: 1%; other: 3%). Because none of the examined studies were prospectively designed, incidence rates could not be determined.

Conclusions

This systematic review and meta-analysis provide the first robust assessment of severe asthma prevalence among European children. Our findings underscore the need for comprehensive research to address knowledge gaps in severe asthma, including determining incidence rates, standardising definitions, investigating regional differences and evaluating comorbidities and treatment strategies.