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Use of and Mortality After Bilateral Mastectomy Compared With Other Surgical Treatments for Breast Cancer in California, 1998-2011

Interview with Allison W. Kurian, MD, MSc, author of Use of and Mortality After Bilateral Mastectomy Compared With Other Surgical Treatments for Breast Cancer in California, 1998-2011




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Comparison of Weight Loss Among Named Diet Programs in Overweight and Obese Adults: A Meta-analysis

Interview with Bradley C. Johnston, PhD, author of Comparison of Weight Loss Among Named Diet Programs in Overweight and Obese Adults: A Meta-analysis




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Management of Sickle Cell Disease

Interview with George R. Buchanan, MD, author of Management of Sickle Cell Disease




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Combination Long-Acting β-Agonists and Inhaled Corticosteroids Compared With Long-Acting β-Agonists Alone in Older Adults With Chronic Obstructive Pulmonary Disease

Interview with Andrea S. Gershon, MD, MSc, author of Combination Long-Acting β-Agonists and Inhaled Corticosteroids Compared With Long-Acting β-Agonists Alone in Older Adults With Chronic Obstructive Pulmonary Disease




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Clinical and Safety Outcomes Associated With Treatment of Acute Venous Thromboembolism: A Systematic Review and Meta-analysis

Interview with Marc Carrier, MD, MSc, author of Clinical and Safety Outcomes Associated With Treatment of Acute Venous Thromboembolism: A Systematic Review and Meta-analysis




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Effect of Enhanced Information, Values Clarification, and Removal of Financial Barriers on Use of Prenatal Genetic Testing

Interview with Miriam Kuppermann, PhD, MPH, author of Effect of Enhanced Information, Values Clarification, and Removal of Financial Barriers on Use of Prenatal Genetic Testing




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Acupuncture for Chronic Knee Pain: A Randomized Clinical Trial

Interview with Kim L. Bennell, PhD, author of Acupuncture for Chronic Knee Pain: A Randomized Clinical Trial




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Prevalence of Antimicrobial Use in US Acute Care Hospitals, May-September 2011

Interview with Shelley S. Magill, MD, PhD, author of Prevalence of Antimicrobial Use in US Acute Care Hospitals, May-September 2011




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Obstetric Quality Indicators and Morbidity

Interview with Elizabeth A Howell, MD, MPP, author of Durability of Benefits of an Outpatient Antimicrobial Stewardship Intervention After Discontinuation of Audit and Feedback




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Climate Change and Global Health Challenges

Interview with Jonathan A. Patz, MD, MPH, author of Climate Change: Challenges and Opportunities for Global Health




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For-Profit Status and Clinical and Economic Outcomes

Interview with Ashish K. Jha, MD, MPH, author of Association Between Hospital Conversions to For-Profit Status and Clinical and Economic Outcomes




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Nonobstructive Coronary Artery Disease and MI

Interview with Thomas M. Maddox, MD, MSc, author of Nonobstructive Coronary Artery Disease and Risk of Myocardial Infarction




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Medicare Hospice Benefit and Poor-Prognosis Cancer

Interview with Ziad Obermeyer, MD, MPhil, author of Association Between the Medicare Hospice Benefit and Health Care Utilization and Costs for Patients With Poor-Prognosis Cancer




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Inpatient STEMI and Treatment and Clinical Outcomes

Interview with George A. Stouffer, MD, author of Association of Inpatient vs Outpatient Onset of ST-Elevation Myocardial Infarction With Treatment and Clinical Outcomes




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Vascular Closure Devices vs Manual Compression

Interview with Stefanie Schulz-Schüpke, MD, author of Comparison of Vascular Closure Devices vs Manual Compression After Femoral Artery Puncture: The ISAR-CLOSURE Randomized Clinical Trial




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Preschool Full or Half Days and School Readiness

Interview with Arthur J. Reynolds, PhD, author of Association of a Full-Day vs Part-Day Preschool Intervention With School Readiness, Attendance, and Parent Involvement




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Medical Liability and Reform

Interview with Michelle M. Mello, JD, PhD, MPhil, author of The Medical Liability Climate and Prospects for Reform




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Resident Duty Hour Reforms and Patient Outcomes

Interview with Mitesh S. Patel, MD, MBA, MS, author of Association of the 2011 ACGME Resident Duty Hour Reforms With Mortality and Readmissions Among Hospitalized Medicare Patients




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Imposition of a MOC Requirement and Outcomes of Care

Interview with Bradley M. Gray, PhD, author of Association Between Imposition of a Maintenance of Certification Requirement and Ambulatory Care-Sensitive Hospitalizations and Health Care Costs




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Glycemic Index, Cardiovascular Disease, and Insulin Sensitivity

Interview with Frank M. Sacks, MD, author of Effects of High vs Low Glycemic Index of Dietary Carbohydrate on Cardiovascular Disease Risk Factors and Insulin Sensitivity




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Effect of Depth and Duration of Cooling on Neonates With HIE

Interview with Seetha Shankaran, MD, author of Effect of Depth and Duration of Cooling on Deaths in the NICU Among Neonates With Hypoxic Ischemic Encephalopathy: A Randomized Clinical Trial




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Treatment of Diabetes and Long-term Mortality

Interview with David M. Nathan, MD, author of Association Between 7 Years of Intensive Treatment of Type 1 Diabetes and Long-term Mortality




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Association Between Bariatric Surgery and Long-term Survival

Interview with David E. Arterburn, MD, MPH and Matthew L. Maciejewski, PhD, authors of Association Between Bariatric Surgery and Long-term Survival




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Breast Cancer Stage at Diagnosis and Survival

Interview with Steven A. Narod, MD, FRCPC, author of Differences in Breast Cancer Stage at Diagnosis and Cancer-Specific Survival by Race and Ethnicity in the United States




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Trends and Outcomes of Intracytoplasmic Sperm Injection

Interview with Sheree L. Boulet, DrPH, MPH, author of Trends in Use of and Reproductive Outcomes Associated With Intracytoplasmic Sperm Injection




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Hematopoietic Stem Cell Transplantation for Multiple Sclerosis

Interview with Richard K. Burt, MD, author of Association of Nonmyeloablative Hematopoietic Stem Cell Transplantation With Neurological Disability in Patients With Relapsing-Remitting Multiple Sclerosis




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MR/Ultrasound Fusion Biopsy for Prostate Cancer

Interview with Peter A. Pinto, MD, author of Comparison of MR/Ultrasound Fusion-Guided Biopsy With Ultrasound-Guided Biopsy for the Diagnosis of Prostate Cancer




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Genetic Variant and Vincristine Peripheral Neuropathy in ALL

Interview with William E. Evans, PharmD, author of Association of an Inherited Genetic Variant With Vincristine-Related Peripheral Neuropathy in Children With Acute Lymphoblastic Leukemia




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Outcomes After Transcatheter Aortic Valve Replacement

Interview with David R. Holmes Jr, MD, author of Clinical Outcomes at 1 Year Following Transcatheter Aortic Valve Replacement




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Diagnostic Concordance in Interpreting Breast Biopsies

Interview with Joann G. Elmore, MD, MPH, author of Diagnostic Concordance Among Pathologists Interpreting Breast Biopsy Specimens




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Hospital Credentialing and Privileging of Surgeons

Interview with Justin B. Dimick, MD, MPH, author of Hospital Credentialing and Privileging of Surgeons: A Potential Safety Blind Spot




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Maternal Diabetes and Autism in Offspring

Interview with Anny H. Xiang, PhD, author of Association of Maternal Diabetes With Autism in Offspring




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Oral Insulin and Immune Responses in Children at Risk for Diabetes

Interview with Ezio Bonifacio, PhD, author of Effects of High-Dose Oral Insulin on Immune Responses in Children at High Risk for Type 1 Diabetes: The Pre-POINT Randomized Clinical Trial




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Subclinical Thyroid Dysfunction and Fracture Risk

Interview with Anne R. Cappola, MD, ScM, author of Subclinical Thyroid Dysfunction and Fracture Risk: A Meta-analysis




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Antidepressant Use Late in Pregnancy and Effects on Newborn

Interview with Krista F. Huybrechts, MS, PhD, author of Antidepressant Use Late in Pregnancy and Risk of Persistent Pulmonary Hypertension of the Newborn




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The ADA and the Supreme Court

Interview with Samuel R. Bagenstos, JD, author of The ADA and the Supreme Court: A Mixed Record




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The ADA, Disability, and Identity

Interview with Eve Hill, JD, author of The ADA, Disability, and Identity




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Why the Americans With Disabilities Act Matters for Genetics

Interview with Ellen Wright Clayton, MD, JD , author of Why the Americans With Disabilities Act Matters for Genetics




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Lifetime Benefits and Costs of Colorectal Cancer Screening

Interview with Chyke A. Doubeni, MD, MPH, author of Variation in Adenoma Detection Rate and the Lifetime Benefits and Cost of Colorectal Cancer Screening: A Microsimulation Model




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Antibiotics vs Appendectomy for Uncomplicated Appendicitis Treatment

JAMA Topic Review: Edward Livingston, MD, FACS, AGAF, Deputy Editor of JAMA, explores how the study by Paulina Salminen, MD, PhD, supports treating appendicitis without surgery




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Medical Marijuana for Treatment of Chronic Pain and Other Problems

Interview with Kevin P. Hill, MD, MHS, author of Medical Marijuana for Treatment of Chronic Pain and Other Medical and Psychiatric Problems: A Clinical Review, and Deepak Cyril D'Souza, MBBS, MD, author of Medical Marijuana: Is the Cart Before the Horse?




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Duration of Oral Anticoagulation After PE

Interview with Francis Couturaud, MD, PhD, author of Six Months vs Extended Oral Anticoagulation After a First Episode of Pulmonary Embolism: The PADIS-PE Randomized Clinical Trial




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Maternal Malignancy and Noninvasive Prenatal Testing

Interview with Diana W. Bianchi, MD, author of Noninvasive Prenatal Testing and Incidental Detection of Occult Maternal Malignancies




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Cardiac Survival After Bystander and First-Responder CPR Intervention

Interview with Carolina Malta Hansen, MD, author of Association of Bystander and First-Responder Intervention With Survival After Out-of-Hospital Cardiac Arrest in North Carolina, 2010-2013




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Managing Atrial Fibrillation

Edward H. Livingston, MD discusses atrial fibrillation with Eric N. Prystowsky, MD, author of Treatment of Atrial Fibrillation. This review article reports that therapy for atrial fibrillation should include rate control for all patients, but maintenance of sinus rhythm with drugs or catheter ablation should be considered on an individual patient basis. Also on the program is a conversation about new technologies to facilitate screening for atrial fibrillation with Leslie Saxon, MD.




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Mortality, Hospitalizations, and Expenditures for the Medicare Population

Interview with Harlan M. Krumholz, MD, SM, author of Mortality, Hospitalizations, and Expenditures for the Medicare Population Aged 65 Years or Older, 1999-2013




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Medicare and Medicaid at 50 Years

Interview with Drew Altman, PhD and William Frist, MD, authors of Medicare and Medicaid at 50 Years: Perspectives of Beneficiaries, Health Care Professionals and Institutions, and Policy Makers




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Mindfulness-Based Stress Reduction for PTSD Among Veterans

Interview with Melissa A. Polusny, PhD, author of Mindfulness-Based Stress Reduction for Posttraumatic Stress Disorder Among Veterans: A Randomized Clinical Trial




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Testosterone and Atherosclerosis in Older Men

Interview with Shalender Bhasin, MBBS, author of Effects of Testosterone Administration for 3 Years on Subclinical Atherosclerosis Progression in Older Men With Low or Low-Normal Testosterone Levels: A Randomized Clinical Trial




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Referrals From Dialysis Facilities for Kidney Transplantation

Interview with Rachel E. Patzer, PhD, MPH, author of Variation in Dialysis Facility Referral for Kidney Transplantation Among Patients With End-Stage Renal Disease in Georgia. This population epidemiology study uses United States Renal Data System data to characterize dialysis facility–level referral for kidney transplant evaluation in Georgia, the US state with the lowest transplantation rates, and patient and facility factors associated with referral and waitlisting.